Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis

FASEB Journal

Volumn 26, Issue 4, 2012, Pages 1640-1651

  Bosmann, Markus ^a   Sarma, J Vidya ^a   Atefi, Gelareh ^a   Zetoune, Firas S ^a   Ward, Peter A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

C5L2; Endotoxic shock; Interleukin 10; Macrophages

Indexed keywords

CD11B ANTIGEN; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; INTERLEUKIN 17; INTERLEUKIN 23; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CD4+ T LYMPHOCYTE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTOXEMIA; ENZYME ACTIVATION; GAMMA DELTA T LYMPHOCYTE; IN VITRO STUDY; INFLAMMATION; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; SEPTIC SHOCK;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD11B; ANTIGENS, DIFFERENTIATION; COMPLEMENT C5A; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; IMMUNITY, INNATE; INTERLEUKIN-10; INTERLEUKIN-17; INTERLEUKIN-23; INTERLEUKIN-23 SUBUNIT P19; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MAP KINASE KINASE 1; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

MUS;

EID: 84860902599     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-199216     Document Type: Article

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