My journey into the world of sphingolipids and sphingolipidoses

Proceedings of the Japan Academy Series B: Physical and Biological Sciences

Volumn 88, Issue 10, 2012, Pages 554-582

  Sandhoff, Konrad ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Endocytosis of membrane lipids; Ganglioside metabolism; Lipid binding proteins; Lipid storage diseases; Lipids regulate endolysosomal proteins; Lysosomal digestion

Indexed keywords

SPHINGOLIPID; SPHINGOLIPID ACTIVATOR PROTEIN;

ANIMAL; BIOSYNTHESIS; BRAIN; CHEMISTRY; ENDOCYTOSIS; ENZYMOLOGY; GENETICS; HUMAN; LIPIDOSIS; LYSOSOME; METABOLISM; PATHOLOGY; REVIEW;

ANIMALS; BRAIN; ENDOCYTOSIS; HUMANS; LYSOSOMES; SPHINGOLIPID ACTIVATOR PROTEINS; SPHINGOLIPIDOSES; SPHINGOLIPIDS;

MUS;

EID: 84871368269     PISSN: 03862208     EISSN: 13492896     Source Type: Journal    
DOI: 10.2183/pjab.88.554     Document Type: Review

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260. Schuette, C.G., Doering, T., Kolter, T. and Sandhoff, K. (1999) The glycosphingolipidosesfrom disease to basic principles of metabolism. Biol. Chem. 380, 759-766.
261. Kwon, H.J., Abi-Mosleh, L., Wang, M.L., Deisenhofer, J., Goldstein, J.L., Brown, M.S. and Infante, R.E. (2009) Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol. Cell 137, 1213-1224.