Accumulation of sphingolipids in SAP-precursor (prosaposin)-deficient fibroblasts occurs as intralysosomal membrane structures and can be completely reversed by treatment with human SAP-precursor

European Journal of Cell Biology

Volumn 73, Issue 1, 1997, Pages 10-18

  Burkhardt, Janis K ^a   Hüttler, Silke ^b   Klein, Andreas ^b   Möbius, Wiebke ^b   Habermann, Anja ^a   Griffiths, Gareth ^a   Sandhoff, Konrad ^b  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Endocytosis; Glycosphingolipids; Intralysosomal vesicles; Lysosomal storage disease; SAP precursor

Indexed keywords

BOVINE SERUM ALBUMIN; CARBON 14; CATION; COLLOIDAL GOLD; FERRITIN; GLYCOSPHINGOLIPID; HYDROLASE; OLIGOSACCHARIDE; PROTEIN PRECURSOR; SPHINGOLIPID; SPHINGOLIPID ACTIVATOR PROTEIN;

ARTICLE; CELL ORGANELLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENDOCYTOSIS; ENDOSOME; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; IMMUNOGOLD STAINING; LYSOSOME MEMBRANE; MEMBRANE VESICLE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN SYNTHESIS;

BOVINAE;

EID: 0343052042     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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