The enzyme-binding region of human GM2-activator protein

FEBS Journal

Volumn 273, Issue 5, 2006, Pages 982-991

  Wendeler, Michaela ^a   Werth, Norbert ^a   Maier, Timm ^b   Schwarzmann, Guenter ^a   Kolter, Thomas ^a   Schoeniger, Maike ^a   Hoffmann, Daniel ^c   Lemm, Thorsten ^a   Saenger, Wolfram ^b   Sandhoff, Konrad ^a  

^a UNIVERSITY OF BONN   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c CENTER OF ADVANCED EUROPEAN STUDIES AND RESEARCH CAESAR   (Germany)

Author keywords

hexosaminidase A; Ganglioside degradation; GM2 activator; Lipid transfer; Lysosome

Indexed keywords

4 METHYLUMBELLIFERYL 2 ACETAMIDO 2 DEOXY 6 SULFO BETA DEXTRO GLUCOPYRANOSIDE; ANION; BETA N ACETYLHEXOSAMINIDASE A; DETERGENT; GANGLIOSIDE GM2 ACTIVATOR PROTEIN; GLUCOPYRANOSIDE; LIPOSOME; UNCLASSIFIED DRUG;

ALPHA HELIX; ANIMAL CELL; ARTICLE; BINDING SITE; BIOPHYSICS; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); DONOR; ENZYME ACTIVATION; ENZYME BINDING; ENZYME MECHANISM; ENZYME SUBUNIT; EVALUATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; FUNCTIONAL ASSESSMENT; GANGLIOSIDOSIS; LIPID BILAYER; LIPID SOLUBILITY; LIPID TRANSPORT; LIPID VESICLE; MEMBRANE STRUCTURE; MOLECULAR DYNAMICS; MUTATION; NEUROLOGIC DISEASE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEFICIENCY; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN IMMOBILIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN VARIANT; SOLUBILIZATION; STORAGE DISEASE; SURFACE PLASMON RESONANCE; WILD TYPE;

ANIMALS; BETA-N-ACETYLHEXOSAMINIDASE; BINDING SITES; CELL LINE; CIRCULAR DICHROISM; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; G(M2) ACTIVATOR PROTEIN; G(M2) GANGLIOSIDE; HUMANS; LIPID BILAYERS; LIPOSOMES; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; MUTAGENESIS, SITE-DIRECTED; RECOMBINANT PROTEINS; SPODOPTERA; SURFACE PLASMON RESONANCE;

ANIMALIA;

EID: 33644941436     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2006.05126.x     Document Type: Article

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