Methylalpinumisoflavone inhibits lipopolysaccharide-induced inflammation in microglial cells by the NF-kappaB and MAPK signaling pathway

Phytotherapy Research

Volumn 26, Issue 12, 2012, Pages 1948-1956

  Lim, Ji Youn ^a   Hwang, Bang Yeon ^b   Hwang, Kwang Woo ^c   Park, So Young ^d  

^a Korea University College of Medicine   (South Korea)

^b Chungbuk National University   (South Korea)

^c Chung Ang University   (South Korea)

^d Dankook University   (South Korea)

Author keywords

anti inflammatory effect; BV2 cells; MAPKs; methylalpinumisoflavone; NF B

Indexed keywords

CYCLOOXYGENASE 2; FLAVONE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; METHYLALPINUMISOFLAVONE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; PROSTAGLANDIN E2; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CUDRANIA TRICUSPIDATA; CYTOKINE PRODUCTION; CYTOPLASM; DOSE RESPONSE; DRUG DETERMINATION; DRUG EFFICACY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; GENE TRANSLOCATION; MICROGLIA; MORACEAE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CYCLOOXYGENASE 2; CYTOKINES; DINOPROSTONE; INFLAMMATION; ISOFLAVONES; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MICE; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II;

MACLURA TRICUSPIDATA;

EID: 84871327749     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4810     Document Type: Article

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