Induction of Nitric-oxide Synthase and Activation of NF-κ B by Interleukin-12 p40 in Microglial Cells

Journal of Biological Chemistry

Volumn 276, Issue 11, 2001, Pages 7899-7905

  Pahan, Kalipada ^a   Sheikh, Faruk G ^c   Liu, Xiaojuan ^a   Hilger, Shilo ^a   McKinney, Michael ^b   Petro, Thomas M ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b MAYO CLINIC   (United States)

^c WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; DISEASES; DNA; NEUROLOGY; PATHOLOGY; PATIENT MONITORING; PHYSIOLOGY; RNA;

NUCLEAR LOCALIZATION; TRANSCRIPTIONAL ACTIVITIES;

NITROGEN OXIDES;

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN P35; PROTEIN P40; PROTEIN P50; INDUCIBLE NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, MOUSE; PROTEIN SUBUNIT;

ANIMAL CELL; ARTICLE; ASTROCYTE; ENZYME ACTIVITY; ENZYME INDUCTION; GLIA CELL; INFLAMMATION; MICROGLIA; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL LINE; DRUG EFFECT; GENETICS; METABOLISM;

ANIMALIA;

ANIMALS; ASTROCYTES; CELL LINE; ENZYME INDUCTION; INTERLEUKIN-12; MACROPHAGES, PERITONEAL; MICE; MICROGLIA; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROTEIN SUBUNITS;

EID: 0035896521     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008262200     Document Type: Article

References (56)

1. Galea, E., Feinstein, D. L., and Reis, D. J. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 10945-10949
2. Koprowski, H., Zheng, Y. M., Heber-Katz, E., Fraser, N., Rorke, L., Fu, Z. F., Hanlon, C., and Dietzshold, B. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 3024-3027
3. Mitrovic, B., Ignarro, L. J., Montestruque, S., Smoll, A., and Merril, J. E. (1994) Neurosci. 61, 575-585
4. Bo, L., Dawson, T. M., Wesselingh, S., Mork, S., Choi, S., Kong, P. A., Hanley, D., and Trapp, B. D. (1994) Ann. Neurol. 36, 778-786
5. Merrill, J. E., Ignarro, L. J., Sherman, M. P., Melinek, J., and Lane, T. E. (1993) J. Immunol. 151, 2132-2141
6. Kolb, H., and Kolb-Bachofen, V. (1992) Immunol. Today 13, 157-160
7. McCatney-Francis, N., Allen, J. B., Mizel, D. E., Albina, J. E., Xie, Q-W, Nathan, C. F., and Wahl, S. M. (1993) J. Ex. Med. 178, 749-754
8. Pahan, K., Sheikh, F. G., Namboodiri, A. M. S., and Singh, I. (1998) J. Biol. Chem. 273, 12219-12226
9. Johnson, A. W., Land, J. M., Thompson, E. J., Bolanos, J. P., Clark, J. B., and Heales, S. J. R. (1995) J. Neurol. Neurosurg. Psychiatry 58, 107-115
10. Brenner, T., Brocke, S., Szafer, F., Sobel, R. A., Parkinson, J. F., Perez, D. H., and Steinman, L. (1997) J. Immunol. 158, 2940-2946
11. Hooper, D. C., Scott, G. S., Zborek, A., Mikheeva, T., Kean, R. B., Koprowski, H., and Spitsin, S. V. (2000) FASEB. J. 14, 691-698
12. Brosan, C. F., Battistini, L., Raine, C. S., Dickson, D. W., Casadevall, A., and Lee, S. C. (1994) Dev. Neurosci. 16, 152-161
13. Hu, S. X., Sheng, W. S., Peterson, P. K., and Chao, C. C. (1995) Glia 15, 491-494
14. Hsieh, C. S., Macatonia, S. E., Tripp, C. S., Wolf, S. F., O'Garra, A., and Murphy, K. M. (1993) Science 260, 547-549
15. Constantinescu, C. S., Goodman, D. B., Hilliard, B., Wysocka, M., and Cohen, J. A. (2000) Neurosci. Lett. 287, 171-174
16. Zipris, D., Greiner, D. L., Malkani, S., Whalen, B., Mordes, J. P., and Rossini, A. A. (1996) J. Immunol. 156, 1315-1321
17. Wolf, S. F., Temple, P. A., Kobayashi, M., Young, D., Dicig, M., Lowe, L., Dzialo, R., Fitz, L., Ferenz, C., and Hewick, R. M. (1991) J. Immunol. 146, 3074-3081
18. Schoenhaut, D. S., Chua, A. O., et al. (1992) J. Immunol. 148, 3433-3440
19. Gately, M. K., Renzetti, L. M., Magram, J., Stern, A. S., Adorini, L., Gubler, U., and Presky, D. H. (1998) Annu. Rev. Immunol. 16, 495-521
20. van Boxel-Dezaire, A. H., Hoff, S. C., et al. (1999) Ann. Neurol. 45, 695-703
21. Fassbender, K., Ragoschke, A., Rossol, S., Schwartz, A., Mielke, O., Paulig, A., and Hennerici, M. (1998) Neurology 51, 753-758
22. Bright, J. J., Musuro, B. F., Du, C., and Sriram, S. (1998) J. Neuroimmunol. 82, 22-30
23. McCarthy, K., and DeVellis, J. (1980) J. Cell Biol. 85, 890-902
24. Giulian, D., and Baker, T. J. (1986) J. Neurosci. 6, 2163-2178
25. Pahan, K., Sheikh, F. G., Namboodiri, A. M. S., and Singh, I. (1998) Free Rad. Biol. Med. 24, 39-48
26. Pahan, K., Liu, X., Wood, C., and Raymond, J. R. (2000) FEBS Lett. 472, 203-207
27. Pahan, K., Liu, X., McKinney, M. J., Wood, C., Sheikh, F. G., and Raymond, J. R. (2000) J. Neurochem. 74, 2288-2295
28. Feinstein, D. L., Galea, E., Roberts, S., Berquist, H., Wang, H., and Reis, D. J. (1994) J. Neurochem. 62, 315-321
29. Pahan, K., Namboodiri, A. M. S., Sheikh, F. G., Smith, B. T., and Singh, I. (1997) J. Biol. Chem. 272, 7786-7791
30. Pahan, K., Sheikh, F. G., Khan, M., Namboodiri, A. M. S., and Singh, I. (1998) J. Biol. Chem. 273, 2591-2600
31. Pahan, K., Raymond, J. R., and Singh, I. (1999) J. Biol. Chem. 274, 7528-7536
32. Bradford, M. (1976) Anal. Biochem. 72, 248-254
33. Dignam, J. D., Lebovitz, R. M., and Roeder, R. G. (1983) Nucleic Acids Res. 11, 1475-1489
34. Aloisi, F., Penna, G., Cerase, J., Menendez Iglesias, B., and Adorini, L. (1997) J. Immunol. 159, 1604-1612
35. Suzumura, A., Sawada, M., and Takayanagi, T. (1998) Brain Res. 787, 139-142
36. Xie, Q., Kashiwabara, Y., and Nathan, C. (1994) J. Biol. Chem. 269, 4705-4708
37. Pahan, K., Sheikh, F. G., Namboodiri, A. M. S., and Singh, I. (1997) J. Clin. Invest. 100, 2671-2679
38. Lin, Y-Z., Yao, S. Y., Veach, R. A., Torgerson, T. R., and Hawiger, J. (1995) J. Biol. Chem. 270, 14255-14258
39. Germann, T., Rude, E., Mattner, F., and Gately, M. K. (1995) Immunol. Today 16, 500-501
40. Stefanova, I., M. L. Corcoran, E. M. Horak, L. M. Wahl, J. B. Bolen, and I. D. Horak. (1993) J. Biol. Chem. 268, 20725-20728
41. Salkowski, C. A., Detore, G., McNally, R., van Rooijen, N., and Vogel, S. N. (1997) J. Immunol. 158, 905-912
42. Beg, A. A., Ruben, S. M., Scheinman, R. I., Haskil, S., Rosen, C. A., and Baldwin, A. S., Jr. (1992) Genes Dev. 6, 1899-1913
43. DiDonato, J. A., Hayakawa, M., Rothwarf, D. M., Zandi, E., and Karin, M. (1997) Nature 388, 548-554
44. Maniatis, T. (1997) Science 278, 818-819
45. Mercurio, F., Zhu, H., Murray, B. W., et al. (1997) Science 278, 860-866
46. Sun, S.-C., Ganchi, P. A., Ballard, D. W., and Greene, W. C. (1993) Science 259, 1912-1915
47. Brown, K., Gerstberger, S., Carlson, L., Franzoso, G., and Siebenlist, U. (1995) Science 267, 1485-1488
48. Qin, Z. H., Wang, Y., Nakai, M., and Chase, T. N. (1998) Mol. Pharmacol. 53, 33-42
49. Wang, X., Wilkinson, V. L., Podlaski, F. J., Wu, C., Stern, A. S., Presky, D. H., and Magram, J. (1999) Eur. J. Immunol. 29, 2007-2013
50. Presky, D. H., Yang, H., Minetti, L. J., Chua, A. O., Nabavi, N., Wu, C. Y., Gately, M. K., and Gubler, U. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 14002-14007
51. Nathan, C. (1992) FASEB. J. 6, 3051-3064
52. Jaffrey, S. R., and Snyder, S. H. (1995) Annu. Rev. Cell Dev. Biol. 11, 417-440
53. Dawson, V. L., Dawson, T. M., London, E. D., Bredt, D. T., and Snyder, S. H. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 6368-6371
54. Drapier, J-C., and Hibbs, J. B. (1988) J. Immunol. 140, 2829-2838
55. Radi, R., Beckman, J. S., Bush, K. M., and Freeman. B. A. (1991) J. Biol. Chem. 266, 4244-4250
56. Wink, D. A., Kasprazak, K. S., et al. (1991) Science 254, 1001-1003