ERK1/2 and p38 mitogen-activated protein kinase mediate iNOS-induced spinal neuron degeneration after acute traumatic spinal cord injury

Life Sciences

Volumn 79, Issue 20, 2006, Pages 1895-1905

  Xu, Zhen ^a   Wang, Bai Ren ^a   Wang, Xi ^a   Kuang, Fang ^a   Duan, Xiao Li ^a   Jiao, Xi Ying ^a   Ju, Gong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Inducible nitric oxide synthase; Macrophages; Microglia; Mitogen activated protein kinase; Neuron; Rat; Spinal cord injury

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MICROGLIA; MORPHOLOGY; NERVE DEGENERATION; NICK END LABELING; NONHUMAN; PHOSPHORYLATION; RAT; RAT STRAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD INJURY; SPINAL CORD NERVE CELL; SPINAL CORD NERVE DEGENERATION; STATISTICAL SIGNIFICANCE; SYNTHESIS; VERTEBRA; WESTERN BLOTTING;

ANIMALS; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE DEGENERATION; NEURONS; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SPINAL CORD INJURIES; UP-REGULATION;

EID: 33749257099     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.06.023     Document Type: Article

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