IL-7 abrogates suppressive activity of human CD4+ CD25 + FOXP3+ regulatory T cells and allows expansion of alloreactive and autoreactive T cells

Journal of Immunology

Volumn 189, Issue 12, 2012, Pages 5649-5658

  Heninger, Anne Kristin ^a   Theil, Anke ^a   Wilhelm, Carmen ^a   Petzold, Cathleen ^a   Huebel, Nicole ^a   Kretschmer, Karsten ^a   Bonifacio, Ezio ^a   Monti, Paolo ^a  

^a CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; AUTOANTIGEN; INTERLEUKIN 2 RECEPTOR GAMMA; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; STAT5 PROTEIN; TRANSCRIPTION FACTOR FOXP3;

ALLOIMMUNITY; ARTICLE; BINDING AFFINITY; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL ASSAY; CELL EXPANSION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; HOMEOSTASIS; IMMUNOREGULATION; INTRACELLULAR SIGNALING; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD4; AUTOANTIGENS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; IMMUNOPHENOTYPING; INTERLEUKIN-10; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; INTERLEUKIN-7; ISOANTIGENS; LYMPHOCYTE ACTIVATION; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY;

EID: 84871152858     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201286     Document Type: Article

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