메뉴 건너뛰기




Volumn 30, Issue 9, 2009, Pages 430-438

Lymphocyte proliferation in immune-mediated diseases

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; ANTIRETROVIRUS AGENT; CYCLOPHOSPHAMIDE; CYTOKINE; IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 15; INTERLEUKIN 6 ANTIBODY; INTERLEUKIN 7; INTERLEUKIN 7 ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; RECOMBINANT INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 68949166331     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2009.06.002     Document Type: Review
Times cited : (81)

References (91)
  • 1
    • 0036672918 scopus 로고    scopus 로고
    • Maintaining the norm: T-cell homeostasis
    • Jameson S.C. Maintaining the norm: T-cell homeostasis. Nat Rev Immunol 2 8 (2002) 547-556
    • (2002) Nat Rev Immunol , vol.2 , Issue.8 , pp. 547-556
    • Jameson, S.C.1
  • 2
    • 33750435941 scopus 로고    scopus 로고
    • Physiologic regulation of central and peripheral T cell tolerance: lessons for therapeutic applications
    • Li L., and Boussiotis V.A. Physiologic regulation of central and peripheral T cell tolerance: lessons for therapeutic applications. J Mol Med 84 11 (2006) 887-899
    • (2006) J Mol Med , vol.84 , Issue.11 , pp. 887-899
    • Li, L.1    Boussiotis, V.A.2
  • 3
    • 0037243278 scopus 로고    scopus 로고
    • Neonates support lymphopenia-induced proliferation
    • Min B., et al. Neonates support lymphopenia-induced proliferation. Immunity 18 1 (2003) 131-140
    • (2003) Immunity , vol.18 , Issue.1 , pp. 131-140
    • Min, B.1
  • 4
    • 16844371602 scopus 로고    scopus 로고
    • T cell homeostasis: keeping useful T cells alive and live T cells useful
    • Jameson S.C. T cell homeostasis: keeping useful T cells alive and live T cells useful. Semin Immunol 17 3 (2005) 231-237
    • (2005) Semin Immunol , vol.17 , Issue.3 , pp. 231-237
    • Jameson, S.C.1
  • 5
    • 33646016305 scopus 로고    scopus 로고
    • The generation of protective memory-like CD8+ T cells during homeostatic proliferation requires CD4+ T cells
    • Hamilton S.E., et al. The generation of protective memory-like CD8+ T cells during homeostatic proliferation requires CD4+ T cells. Nat Immunol 7 5 (2006) 475-481
    • (2006) Nat Immunol , vol.7 , Issue.5 , pp. 475-481
    • Hamilton, S.E.1
  • 6
    • 0034698931 scopus 로고    scopus 로고
    • Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation
    • Goldrath A.W., et al. Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation. J Exp Med 192 4 (2000) 557-564
    • (2000) J Exp Med , vol.192 , Issue.4 , pp. 557-564
    • Goldrath, A.W.1
  • 7
    • 0034698828 scopus 로고    scopus 로고
    • Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells
    • Cho B.K., et al. Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells. J Exp Med 192 4 (2000) 549-556
    • (2000) J Exp Med , vol.192 , Issue.4 , pp. 549-556
    • Cho, B.K.1
  • 8
    • 11144221749 scopus 로고    scopus 로고
    • The new paradigm of T-cell homeostatic proliferation-induced autoimmunity
    • Baccala R., and Theofilopoulos A.N. The new paradigm of T-cell homeostatic proliferation-induced autoimmunity. Trends Immunol 26 1 (2005) 5-8
    • (2005) Trends Immunol , vol.26 , Issue.1 , pp. 5-8
    • Baccala, R.1    Theofilopoulos, A.N.2
  • 9
    • 15744381256 scopus 로고    scopus 로고
    • A causal link between lymphopenia and autoimmunity
    • Khoruts A., and Fraser J.M. A causal link between lymphopenia and autoimmunity. Immunol Lett 98 1 (2005) 23-31
    • (2005) Immunol Lett , vol.98 , Issue.1 , pp. 23-31
    • Khoruts, A.1    Fraser, J.M.2
  • 10
    • 33746189876 scopus 로고    scopus 로고
    • Autoimmunity during lymphopenia: a two-hit model
    • Krupica Jr. T., et al. Autoimmunity during lymphopenia: a two-hit model. Clin Immunol 120 2 (2006) 121-128
    • (2006) Clin Immunol , vol.120 , Issue.2 , pp. 121-128
    • Krupica Jr., T.1
  • 11
    • 24744441702 scopus 로고    scopus 로고
    • T cell homeostasis in tolerance and immunity
    • Marleau A.M., and Sarvetnick N. T cell homeostasis in tolerance and immunity. J Leukoc Biol 78 3 (2005) 575-584
    • (2005) J Leukoc Biol , vol.78 , Issue.3 , pp. 575-584
    • Marleau, A.M.1    Sarvetnick, N.2
  • 12
    • 4444318073 scopus 로고    scopus 로고
    • Lymphopenia and autoimmune diseases
    • Schulze-Koops H. Lymphopenia and autoimmune diseases. Arthritis Res Ther 6 4 (2004) 178-180
    • (2004) Arthritis Res Ther , vol.6 , Issue.4 , pp. 178-180
    • Schulze-Koops, H.1
  • 13
    • 33645289121 scopus 로고    scopus 로고
    • CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs
    • Shiow L.R., et al. CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs. Nature 440 7083 (2006) 540-544
    • (2006) Nature , vol.440 , Issue.7083 , pp. 540-544
    • Shiow, L.R.1
  • 14
    • 34250762786 scopus 로고    scopus 로고
    • CD24: a genetic checkpoint in T cell homeostasis and autoimmune diseases
    • Liu Y., and Zheng P. CD24: a genetic checkpoint in T cell homeostasis and autoimmune diseases. Trends Immunol 28 7 (2007) 315-320
    • (2007) Trends Immunol , vol.28 , Issue.7 , pp. 315-320
    • Liu, Y.1    Zheng, P.2
  • 15
    • 58049217366 scopus 로고    scopus 로고
    • Memory-like CD8+ and CD4+ T cells cooperate to break peripheral tolerance under lymphopenic conditions
    • Le Saout C., et al. Memory-like CD8+ and CD4+ T cells cooperate to break peripheral tolerance under lymphopenic conditions. Proc Natl Acad Sci U S A 105 49 (2008) 19414-19419
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.49 , pp. 19414-19419
    • Le Saout, C.1
  • 16
    • 33747412966 scopus 로고    scopus 로고
    • Lymphopenia-driven CD8(+) T cells are resistant to antigen-induced tolerance in NOD.scid mice
    • Long B., et al. Lymphopenia-driven CD8(+) T cells are resistant to antigen-induced tolerance in NOD.scid mice. Eur J Immunol 36 8 (2006) 2003-2012
    • (2006) Eur J Immunol , vol.36 , Issue.8 , pp. 2003-2012
    • Long, B.1
  • 17
    • 18644376988 scopus 로고    scopus 로고
    • Spontaneous and homeostatic proliferation of CD4 T cells are regulated by different mechanisms
    • Min B., et al. Spontaneous and homeostatic proliferation of CD4 T cells are regulated by different mechanisms. J Immunol 174 10 (2005) 6039-6044
    • (2005) J Immunol , vol.174 , Issue.10 , pp. 6039-6044
    • Min, B.1
  • 18
    • 47249163695 scopus 로고    scopus 로고
    • Regulatory CD4+CD25+Foxp3+ T cells selectively inhibit the spontaneous form of lymphopenia-induced proliferation of naive T cells
    • Winstead C.J., et al. Regulatory CD4+CD25+Foxp3+ T cells selectively inhibit the spontaneous form of lymphopenia-induced proliferation of naive T cells. J Immunol 180 11 (2008) 7305-7317
    • (2008) J Immunol , vol.180 , Issue.11 , pp. 7305-7317
    • Winstead, C.J.1
  • 19
    • 43549090666 scopus 로고    scopus 로고
    • IL-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8+ T cells
    • Tajima M., et al. IL-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8+ T cells. J Exp Med 205 5 (2008) 1019-1027
    • (2008) J Exp Med , vol.205 , Issue.5 , pp. 1019-1027
    • Tajima, M.1
  • 20
    • 36549014534 scopus 로고    scopus 로고
    • T cell immune reconstitution following lymphodepletion
    • Williams K.M., et al. T cell immune reconstitution following lymphodepletion. Semin Immunol 19 5 (2007) 318-330
    • (2007) Semin Immunol , vol.19 , Issue.5 , pp. 318-330
    • Williams, K.M.1
  • 21
    • 1642415714 scopus 로고    scopus 로고
    • Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire
    • Min B., et al. Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire. Proc Natl Acad Sci U S A 101 11 (2004) 3874-3879
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.11 , pp. 3874-3879
    • Min, B.1
  • 22
    • 33749146781 scopus 로고    scopus 로고
    • CD25+CD4+ regulatory T cells and memory T cells prevent lymphopenia-induced proliferation of naive T cells in transient states of lymphopenia
    • Bourgeois C., and Stockinger B. CD25+CD4+ regulatory T cells and memory T cells prevent lymphopenia-induced proliferation of naive T cells in transient states of lymphopenia. J Immunol 177 7 (2006) 4558-4566
    • (2006) J Immunol , vol.177 , Issue.7 , pp. 4558-4566
    • Bourgeois, C.1    Stockinger, B.2
  • 23
    • 20144363585 scopus 로고    scopus 로고
    • Recent immune status determines the source of antigens that drive homeostatic T cell expansion
    • Kieper W.C., et al. Recent immune status determines the source of antigens that drive homeostatic T cell expansion. J Immunol 174 6 (2005) 3158-3163
    • (2005) J Immunol , vol.174 , Issue.6 , pp. 3158-3163
    • Kieper, W.C.1
  • 24
    • 22444441469 scopus 로고    scopus 로고
    • Control of peripheral T-lymphocyte tolerance in neonates and adults
    • Arnold B., et al. Control of peripheral T-lymphocyte tolerance in neonates and adults. Trends Immunol 26 8 (2005) 406-411
    • (2005) Trends Immunol , vol.26 , Issue.8 , pp. 406-411
    • Arnold, B.1
  • 25
    • 5144228026 scopus 로고    scopus 로고
    • Regulatory potential and control of Foxp3 expression in newborn CD4+ T cells
    • Dujardin H.C., et al. Regulatory potential and control of Foxp3 expression in newborn CD4+ T cells. Proc Natl Acad Sci U S A 101 40 (2004) 14473-14478
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.40 , pp. 14473-14478
    • Dujardin, H.C.1
  • 26
    • 3142743111 scopus 로고    scopus 로고
    • Neonatal adaptive immunity comes of age
    • Adkins B., et al. Neonatal adaptive immunity comes of age. Nat Rev Immunol 4 7 (2004) 553-564
    • (2004) Nat Rev Immunol , vol.4 , Issue.7 , pp. 553-564
    • Adkins, B.1
  • 27
    • 0032515016 scopus 로고    scopus 로고
    • Control of neonatal tolerance to tissue antigens by peripheral T cell trafficking
    • Alferink J., et al. Control of neonatal tolerance to tissue antigens by peripheral T cell trafficking. Science 282 5392 (1998) 1338-1341
    • (1998) Science , vol.282 , Issue.5392 , pp. 1338-1341
    • Alferink, J.1
  • 28
    • 33751303775 scopus 로고    scopus 로고
    • Infection and musculoskeletal conditions: Rheumatologic complications of HIV infection
    • Reveille J.D., and Williams F.M. Infection and musculoskeletal conditions: Rheumatologic complications of HIV infection. Best Pract Res Clin Rheumatol 20 6 (2006) 1159-1179
    • (2006) Best Pract Res Clin Rheumatol , vol.20 , Issue.6 , pp. 1159-1179
    • Reveille, J.D.1    Williams, F.M.2
  • 30
    • 0027163182 scopus 로고
    • CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells
    • Morrissey P.J., et al. CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells. J Exp Med 178 1 (1993) 237-244
    • (1993) J Exp Med , vol.178 , Issue.1 , pp. 237-244
    • Morrissey, P.J.1
  • 31
    • 43049130746 scopus 로고    scopus 로고
    • Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells
    • Monti P., et al. Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells. J Clin Invest 118 5 (2008) 1806-1814
    • (2008) J Clin Invest , vol.118 , Issue.5 , pp. 1806-1814
    • Monti, P.1
  • 32
    • 42949131224 scopus 로고    scopus 로고
    • CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity
    • Calzascia T., et al. CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity. Proc Natl Acad Sci U S A 105 8 (2008) 2999-3004
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.8 , pp. 2999-3004
    • Calzascia, T.1
  • 33
    • 44849087807 scopus 로고    scopus 로고
    • Defective positive selection results in T cell lymphopenia and increased autoimmune diabetes in ADAP-deficient BDC2
    • Zou L., et al. Defective positive selection results in T cell lymphopenia and increased autoimmune diabetes in ADAP-deficient BDC2. 5-C57BL/6 mice. Eur J Immunol 38 4 (2008) 986-994
    • (2008) 5-C57BL/6 mice. Eur J Immunol , vol.38 , Issue.4 , pp. 986-994
    • Zou, L.1
  • 34
    • 0034255127 scopus 로고    scopus 로고
    • T cell homeostasis in patients with rheumatoid arthritis
    • Koetz K., et al. T cell homeostasis in patients with rheumatoid arthritis. Proc Natl Acad Sci U S A 97 16 (2000) 9203-9208
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.16 , pp. 9203-9208
    • Koetz, K.1
  • 35
    • 32444447027 scopus 로고    scopus 로고
    • Prevention of spontaneous arthritis by inhibiting homeostatic expansion of autoreactive CD4+ T cells in the K/BxN mouse model
    • Jang E., et al. Prevention of spontaneous arthritis by inhibiting homeostatic expansion of autoreactive CD4+ T cells in the K/BxN mouse model. Arthritis Rheum 54 2 (2006) 492-498
    • (2006) Arthritis Rheum , vol.54 , Issue.2 , pp. 492-498
    • Jang, E.1
  • 36
    • 33745042388 scopus 로고    scopus 로고
    • Autoimmune arthritis associated with mutated interleukin (IL)-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+ T cells
    • Sawa S., et al. Autoimmune arthritis associated with mutated interleukin (IL)-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+ T cells. J Exp Med 203 6 (2006) 1459-1470
    • (2006) J Exp Med , vol.203 , Issue.6 , pp. 1459-1470
    • Sawa, S.1
  • 37
    • 34248176213 scopus 로고    scopus 로고
    • Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model
    • Khiong K., et al. Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model. J Clin Invest 117 5 (2007) 1270-1281
    • (2007) J Clin Invest , vol.117 , Issue.5 , pp. 1270-1281
    • Khiong, K.1
  • 38
    • 21344438431 scopus 로고    scopus 로고
    • Tumor immunity via homeostatic T cell proliferation: mechanistic aspects and clinical perspectives
    • Baccala R., et al. Tumor immunity via homeostatic T cell proliferation: mechanistic aspects and clinical perspectives. Springer Semin Immunopathol 27 1 (2005) 75-85
    • (2005) Springer Semin Immunopathol , vol.27 , Issue.1 , pp. 75-85
    • Baccala, R.1
  • 39
    • 0036076114 scopus 로고    scopus 로고
    • T cell homeostatic proliferation elicits effective antitumor autoimmunity
    • Dummer W., et al. T cell homeostatic proliferation elicits effective antitumor autoimmunity. J Clin Invest 110 2 (2002) 185-192
    • (2002) J Clin Invest , vol.110 , Issue.2 , pp. 185-192
    • Dummer, W.1
  • 40
    • 20244366111 scopus 로고    scopus 로고
    • Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
    • Dudley M.E., et al. Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J Clin Oncol 23 10 (2005) 2346-2357
    • (2005) J Clin Oncol , vol.23 , Issue.10 , pp. 2346-2357
    • Dudley, M.E.1
  • 41
    • 33749135271 scopus 로고    scopus 로고
    • Homeostatic proliferation as an isolated variable reverses CD8+ T cell anergy and promotes tumor rejection
    • Brown I.E., et al. Homeostatic proliferation as an isolated variable reverses CD8+ T cell anergy and promotes tumor rejection. J Immunol 177 7 (2006) 4521-4529
    • (2006) J Immunol , vol.177 , Issue.7 , pp. 4521-4529
    • Brown, I.E.1
  • 42
    • 25844484607 scopus 로고    scopus 로고
    • Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells
    • Gattinoni L., et al. Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells. J Exp Med 202 7 (2005) 907-912
    • (2005) J Exp Med , vol.202 , Issue.7 , pp. 907-912
    • Gattinoni, L.1
  • 43
    • 33745083070 scopus 로고    scopus 로고
    • CD8+ T-cell memory in tumor immunology and immunotherapy
    • Klebanoff C.A., et al. CD8+ T-cell memory in tumor immunology and immunotherapy. Immunol Rev 211 (2006) 214-224
    • (2006) Immunol Rev , vol.211 , pp. 214-224
    • Klebanoff, C.A.1
  • 44
    • 33846787125 scopus 로고    scopus 로고
    • Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8 T cells
    • Wrzesinski C., et al. Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8 T cells. J Clin Invest 117 2 (2007) 492-501
    • (2007) J Clin Invest , vol.117 , Issue.2 , pp. 492-501
    • Wrzesinski, C.1
  • 45
    • 0034606276 scopus 로고    scopus 로고
    • Melanocyte destruction after antigen-specific immunotherapy of melanoma: direct evidence of t cell-mediated vitiligo
    • Yee C., et al. Melanocyte destruction after antigen-specific immunotherapy of melanoma: direct evidence of t cell-mediated vitiligo. J Exp Med 192 11 (2000) 1637-1644
    • (2000) J Exp Med , vol.192 , Issue.11 , pp. 1637-1644
    • Yee, C.1
  • 46
    • 45849143648 scopus 로고    scopus 로고
    • Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity
    • Palmer D.C., et al. Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity. Proc Natl Acad Sci U S A 105 23 (2008) 8061-8066
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.23 , pp. 8061-8066
    • Palmer, D.C.1
  • 47
    • 65249149609 scopus 로고    scopus 로고
    • Melan-A-specific Cytotoxic T Cells Are Associated with Tumor Regression and Autoimmunity Following Treatment with Anti-CTLA-4
    • Klein O., et al. Melan-A-specific Cytotoxic T Cells Are Associated with Tumor Regression and Autoimmunity Following Treatment with Anti-CTLA-4. Clin Cancer Res (2009)
    • (2009) Clin Cancer Res
    • Klein, O.1
  • 48
    • 0037124362 scopus 로고    scopus 로고
    • Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells
    • Goldrath A.W., et al. Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells. J Exp Med 195 12 (2002) 1515-1522
    • (2002) J Exp Med , vol.195 , Issue.12 , pp. 1515-1522
    • Goldrath, A.W.1
  • 49
    • 0038487052 scopus 로고    scopus 로고
    • Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells
    • Seddon B., et al. Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells. Nat Immunol 4 7 (2003) 680-686
    • (2003) Nat Immunol , vol.4 , Issue.7 , pp. 680-686
    • Seddon, B.1
  • 50
    • 33644816267 scopus 로고    scopus 로고
    • Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors
    • Teague R.M., et al. Interleukin-15 rescues tolerant CD8+ T cells for use in adoptive immunotherapy of established tumors. Nat Med 12 3 (2006) 335-341
    • (2006) Nat Med , vol.12 , Issue.3 , pp. 335-341
    • Teague, R.M.1
  • 51
    • 1942453326 scopus 로고    scopus 로고
    • Homeostatic expansion of T cells during immune insufficiency generates autoimmunity
    • King C., et al. Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. Cell 117 2 (2004) 265-277
    • (2004) Cell , vol.117 , Issue.2 , pp. 265-277
    • King, C.1
  • 52
    • 52349088182 scopus 로고    scopus 로고
    • IL-21 limits peripheral lymphocyte numbers through T cell homeostatic mechanisms
    • Datta S., and Sarvetnick N.E. IL-21 limits peripheral lymphocyte numbers through T cell homeostatic mechanisms. PLoS ONE 3 9 (2008) e3118
    • (2008) PLoS ONE , vol.3 , Issue.9
    • Datta, S.1    Sarvetnick, N.E.2
  • 53
    • 52949091915 scopus 로고    scopus 로고
    • IL-21 signaling is critical for the development of type I diabetes in the NOD mouse
    • Spolski R., et al. IL-21 signaling is critical for the development of type I diabetes in the NOD mouse. Proc Natl Acad Sci U S A 105 37 (2008) 14028-14033
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.37 , pp. 14028-14033
    • Spolski, R.1
  • 54
    • 65549165290 scopus 로고    scopus 로고
    • Interleukin-21 is required for the development of type 1 diabetes in NOD mice
    • Sutherland A.P., et al. Interleukin-21 is required for the development of type 1 diabetes in NOD mice. Diabetes 58 5 (2009) 1144-1155
    • (2009) Diabetes , vol.58 , Issue.5 , pp. 1144-1155
    • Sutherland, A.P.1
  • 55
    • 0032992530 scopus 로고    scopus 로고
    • The lymphopenia mutation of the BB rat causes inappropriate apoptosis of mature thymocytes
    • Hernandez-Hoyos G., et al. The lymphopenia mutation of the BB rat causes inappropriate apoptosis of mature thymocytes. Eur J Immunol 29 6 (1999) 1832-1841
    • (1999) Eur J Immunol , vol.29 , Issue.6 , pp. 1832-1841
    • Hernandez-Hoyos, G.1
  • 56
    • 68849084141 scopus 로고    scopus 로고
    • IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab Campath-1H)
    • Jones J.L., et al. IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab Campath-1H). J Clin Invest. [Epub ahead of print] (2009)
    • (2009) J Clin Invest. [Epub ahead of print]
    • Jones, J.L.1
  • 57
    • 31044431958 scopus 로고    scopus 로고
    • Control of homeostatic proliferation by regulatory T cells
    • Shen S., et al. Control of homeostatic proliferation by regulatory T cells. J Clin Invest 115 12 (2005) 3517-3526
    • (2005) J Clin Invest , vol.115 , Issue.12 , pp. 3517-3526
    • Shen, S.1
  • 58
    • 33750833099 scopus 로고    scopus 로고
    • Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+Foxp3+ regulatory T cells
    • Brode S., et al. Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+Foxp3+ regulatory T cells. J Immunol 177 10 (2006) 6603-6612
    • (2006) J Immunol , vol.177 , Issue.10 , pp. 6603-6612
    • Brode, S.1
  • 59
    • 43449120940 scopus 로고    scopus 로고
    • Mechanisms of T regulatory cell function
    • Askenasy N., et al. Mechanisms of T regulatory cell function. Autoimmun Rev 7 5 (2008) 370-375
    • (2008) Autoimmun Rev , vol.7 , Issue.5 , pp. 370-375
    • Askenasy, N.1
  • 60
    • 17844370566 scopus 로고    scopus 로고
    • A major role for memory CD4 T cells in the control of lymphopenia-induced proliferation of naive CD4 T cells
    • Bourgeois C., et al. A major role for memory CD4 T cells in the control of lymphopenia-induced proliferation of naive CD4 T cells. J Immunol 174 9 (2005) 5316-5323
    • (2005) J Immunol , vol.174 , Issue.9 , pp. 5316-5323
    • Bourgeois, C.1
  • 61
    • 53149085302 scopus 로고    scopus 로고
    • Homeostatic proliferation in the mice with germline FoxP3 mutation and its contribution to fatal autoimmunity
    • Chang X., et al. Homeostatic proliferation in the mice with germline FoxP3 mutation and its contribution to fatal autoimmunity. J Immunol 181 4 (2008) 2399-2406
    • (2008) J Immunol , vol.181 , Issue.4 , pp. 2399-2406
    • Chang, X.1
  • 62
    • 0037097503 scopus 로고    scopus 로고
    • Cutting edge: depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease
    • McHugh R.S., and Shevach E.M. Cutting edge: depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease. J Immunol 168 12 (2002) 5979-5983
    • (2002) J Immunol , vol.168 , Issue.12 , pp. 5979-5983
    • McHugh, R.S.1    Shevach, E.M.2
  • 63
    • 34248229621 scopus 로고    scopus 로고
    • A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome
    • Marrella V., et al. A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome. J Clin Invest 117 5 (2007) 1260-1269
    • (2007) J Clin Invest , vol.117 , Issue.5 , pp. 1260-1269
    • Marrella, V.1
  • 64
    • 33847373481 scopus 로고    scopus 로고
    • No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes
    • Brusko T., et al. No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes. Diabetes 56 3 (2007) 604-612
    • (2007) Diabetes , vol.56 , Issue.3 , pp. 604-612
    • Brusko, T.1
  • 65
    • 1542619331 scopus 로고    scopus 로고
    • Suppression of CD4+ T lymphocyte effector functions by CD4+CD25+ cells in vivo
    • Martin B., et al. Suppression of CD4+ T lymphocyte effector functions by CD4+CD25+ cells in vivo. J Immunol 172 6 (2004) 3391-3398
    • (2004) J Immunol , vol.172 , Issue.6 , pp. 3391-3398
    • Martin, B.1
  • 66
    • 44849105008 scopus 로고    scopus 로고
    • Homeostatic proliferation of lymphocytes results in augmented memory-like function and accelerated allograft rejection
    • Moxham V.F., et al. Homeostatic proliferation of lymphocytes results in augmented memory-like function and accelerated allograft rejection. J Immunol 180 6 (2008) 3910-3918
    • (2008) J Immunol , vol.180 , Issue.6 , pp. 3910-3918
    • Moxham, V.F.1
  • 67
    • 34547629044 scopus 로고    scopus 로고
    • Interleukin-2 administration alters the CD4+FOXP3+ T-cell pool and tumor trafficking in patients with ovarian carcinoma
    • Wei S., et al. Interleukin-2 administration alters the CD4+FOXP3+ T-cell pool and tumor trafficking in patients with ovarian carcinoma. Cancer Res 67 15 (2007) 7487-7494
    • (2007) Cancer Res , vol.67 , Issue.15 , pp. 7487-7494
    • Wei, S.1
  • 68
    • 30744458573 scopus 로고    scopus 로고
    • Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells
    • Zhang H., et al. Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells. Nat Med 11 11 (2005) 1238-1243
    • (2005) Nat Med , vol.11 , Issue.11 , pp. 1238-1243
    • Zhang, H.1
  • 69
    • 49649121241 scopus 로고    scopus 로고
    • Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma
    • Kline J., et al. Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma. Clin Cancer Res 14 10 (2008) 3156-3167
    • (2008) Clin Cancer Res , vol.14 , Issue.10 , pp. 3156-3167
    • Kline, J.1
  • 70
    • 34247559064 scopus 로고    scopus 로고
    • Inability to mediate prolonged reduction of regulatory T Cells after transfer of autologous CD25-depleted PBMC and interleukin-2 after lymphodepleting chemotherapy
    • Powell Jr. D.J., et al. Inability to mediate prolonged reduction of regulatory T Cells after transfer of autologous CD25-depleted PBMC and interleukin-2 after lymphodepleting chemotherapy. J Immunother 30 4 (2007) 438-447
    • (2007) J Immunother , vol.30 , Issue.4 , pp. 438-447
    • Powell Jr., D.J.1
  • 71
    • 44449162969 scopus 로고    scopus 로고
    • Autoimmunity in severe combined immunodeficiency (SCID): lessons from patients and experimental models
    • Milner J.D., et al. Autoimmunity in severe combined immunodeficiency (SCID): lessons from patients and experimental models. J Clin Immunol 28 Suppl 1 (2008) S29-33
    • (2008) J Clin Immunol 28 Suppl , vol.1
    • Milner, J.D.1
  • 72
    • 39449126502 scopus 로고    scopus 로고
    • The Foxp3+ regulatory T cell: a jack of all trades, master of regulation
    • Tang Q., and Bluestone J.A. The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat Immunol 9 3 (2008) 239-244
    • (2008) Nat Immunol , vol.9 , Issue.3 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 73
    • 43049174722 scopus 로고    scopus 로고
    • Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
    • Tang Q., et al. Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity 28 5 (2008) 687-697
    • (2008) Immunity , vol.28 , Issue.5 , pp. 687-697
    • Tang, Q.1
  • 74
    • 35748959365 scopus 로고    scopus 로고
    • IL-21 induces apoptosis of antigen-specific CD8+ T lymphocytes
    • Barker B.R., et al. IL-21 induces apoptosis of antigen-specific CD8+ T lymphocytes. J Immunol 179 6 (2007) 3596-3603
    • (2007) J Immunol , vol.179 , Issue.6 , pp. 3596-3603
    • Barker, B.R.1
  • 75
    • 65549122918 scopus 로고    scopus 로고
    • Autoantibodies against galectin-8: their specificity, association with lymphopenia in systemic lupus erythematosus and detection in rheumatoid arthritis and acute inflammation
    • Massardo L., et al. Autoantibodies against galectin-8: their specificity, association with lymphopenia in systemic lupus erythematosus and detection in rheumatoid arthritis and acute inflammation. Lupus 18 6 (2009) 539-546
    • (2009) Lupus , vol.18 , Issue.6 , pp. 539-546
    • Massardo, L.1
  • 76
    • 0035657302 scopus 로고    scopus 로고
    • Lymphopenia in occupational pulmonary silicosis with or without autoimmune disease
    • Subra J.F., et al. Lymphopenia in occupational pulmonary silicosis with or without autoimmune disease. Clin Exp Immunol 126 3 (2001) 540-544
    • (2001) Clin Exp Immunol , vol.126 , Issue.3 , pp. 540-544
    • Subra, J.F.1
  • 77
    • 58149247985 scopus 로고    scopus 로고
    • Rheumatologic and autoimmune manifestations of primary immunodeficiency disorders
    • Goyal R., et al. Rheumatologic and autoimmune manifestations of primary immunodeficiency disorders. Curr Opin Rheumatol 21 1 (2009) 78-84
    • (2009) Curr Opin Rheumatol , vol.21 , Issue.1 , pp. 78-84
    • Goyal, R.1
  • 78
    • 56349102675 scopus 로고    scopus 로고
    • Breakdown of T cell tolerance and autoimmunity in primary immunodeficiency - lessons learned from monogenic disorders in mice and men
    • Westerberg L.S., et al. Breakdown of T cell tolerance and autoimmunity in primary immunodeficiency - lessons learned from monogenic disorders in mice and men. Curr Opin Immunol 20 6 (2008) 646-654
    • (2008) Curr Opin Immunol , vol.20 , Issue.6 , pp. 646-654
    • Westerberg, L.S.1
  • 79
    • 33947330461 scopus 로고    scopus 로고
    • Viral infections as potential triggers of type 1 diabetes
    • van der Werf N., et al. Viral infections as potential triggers of type 1 diabetes. Diabetes Metab Res Rev 23 3 (2007) 169-183
    • (2007) Diabetes Metab Res Rev , vol.23 , Issue.3 , pp. 169-183
    • van der Werf, N.1
  • 80
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot J.D., et al. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4 4 (2003) 330-336
    • (2003) Nat Immunol , vol.4 , Issue.4 , pp. 330-336
    • Fontenot, J.D.1
  • 81
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S., et al. Control of regulatory T cell development by the transcription factor Foxp3. Science 299 5609 (2003) 1057-1061
    • (2003) Science , vol.299 , Issue.5609 , pp. 1057-1061
    • Hori, S.1
  • 82
    • 36249022697 scopus 로고    scopus 로고
    • Competition for cytokines: T(reg) cells take all
    • Scheffold A., et al. Competition for cytokines: T(reg) cells take all. Nat Immunol 8 12 (2007) 1285-1287
    • (2007) Nat Immunol , vol.8 , Issue.12 , pp. 1285-1287
    • Scheffold, A.1
  • 83
    • 33846287885 scopus 로고    scopus 로고
    • Lymphopenic mice reconstituted with limited repertoire T cells develop severe, multiorgan, Th2-associated inflammatory disease
    • Milner J.D., et al. Lymphopenic mice reconstituted with limited repertoire T cells develop severe, multiorgan, Th2-associated inflammatory disease. Proc Natl Acad Sci U S A 104 2 (2007) 576-581
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.2 , pp. 576-581
    • Milner, J.D.1
  • 84
    • 0035162560 scopus 로고    scopus 로고
    • Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
    • Brunkow M.E., et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet 27 1 (2001) 68-73
    • (2001) Nat Genet , vol.27 , Issue.1 , pp. 68-73
    • Brunkow, M.E.1
  • 85
    • 33846485153 scopus 로고    scopus 로고
    • Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
    • Kim J.M., et al. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat Immunol 8 2 (2007) 191-197
    • (2007) Nat Immunol , vol.8 , Issue.2 , pp. 191-197
    • Kim, J.M.1
  • 86
    • 33846423147 scopus 로고    scopus 로고
    • Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease
    • Lahl K., et al. Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease. J Exp Med 204 1 (2007) 57-63
    • (2007) J Exp Med , vol.204 , Issue.1 , pp. 57-63
    • Lahl, K.1
  • 87
    • 0037446531 scopus 로고    scopus 로고
    • Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells
    • Mottet C., et al. Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells. J Immunol 170 8 (2003) 3939-3943
    • (2003) J Immunol , vol.170 , Issue.8 , pp. 3939-3943
    • Mottet, C.1
  • 88
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S., et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 155 3 (1995) 1151-1164
    • (1995) J Immunol , vol.155 , Issue.3 , pp. 1151-1164
    • Sakaguchi, S.1
  • 89
    • 26844476814 scopus 로고    scopus 로고
    • The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis
    • Chang X., et al. The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis. J Exp Med 202 8 (2005) 1141-1151
    • (2005) J Exp Med , vol.202 , Issue.8 , pp. 1141-1151
    • Chang, X.1
  • 90
    • 45949099261 scopus 로고    scopus 로고
    • Cutting edge: Broad expression of the FoxP3 locus in epithelial cells: a caution against early interpretation of fatal inflammatory diseases following in vivo depletion of FoxP3-expressing cells
    • Chen G.Y., et al. Cutting edge: Broad expression of the FoxP3 locus in epithelial cells: a caution against early interpretation of fatal inflammatory diseases following in vivo depletion of FoxP3-expressing cells. J Immunol 180 8 (2008) 5163-5166
    • (2008) J Immunol , vol.180 , Issue.8 , pp. 5163-5166
    • Chen, G.Y.1
  • 91
    • 33947427514 scopus 로고    scopus 로고
    • Lack of Foxp3 function and expression in the thymic epithelium
    • Liston A., et al. Lack of Foxp3 function and expression in the thymic epithelium. J Exp Med 204 3 (2007) 475-480
    • (2007) J Exp Med , vol.204 , Issue.3 , pp. 475-480
    • Liston, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.