Macrophage migration inhibitory factor (MIF) enhances palmitic acid-and glucose-induced murine beta cell dysfunction and destruction in vitro

Growth Factors

Volumn 30, Issue 6, 2012, Pages 385-393

  Stojanovic, Ivana ^a,b   Saksida, Tamara ^a   Timotijevic, Gordana ^a   Sandler, Stellan ^b   Stosic Grujicic, Stanislava ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Apoptosis; Glucose; Macrophage migration inhibitory factor; Palmitic acid; Pancreatic islets; Type 2 diabetes

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA ACTIN; BIM PROTEIN; CASPASE 3; CASPASE 9; GLUCOSE; INSULIN; MACROPHAGE MIGRATION INHIBITION FACTOR; PALMITIC ACID; PROTEIN BAX; PROTEIN BCL XL; PROTEIN BID; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TRANSCRIPTION FACTOR PDX 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL DEATH; CELL DESTRUCTION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE SILENCING; GLUCOSE OXIDATION; IN VITRO STUDY; MALE; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MOLECULAR MIMICRY; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; OUTCOME ASSESSMENT; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE; CYTOKINES; DIABETES MELLITUS, TYPE 2; DNA FRAGMENTATION; GENE EXPRESSION PROFILING; GLUCOSE; INSULIN-SECRETING CELLS; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MALE; MICE; MICE, INBRED C57BL; PALMITIC ACID; TETRAZOLIUM SALTS; THIAZOLES;

MURINAE;

EID: 84871040863     PISSN: 08977194     EISSN: 10292292     Source Type: Journal    
DOI: 10.3109/08977194.2012.734506     Document Type: Article

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