메뉴 건너뛰기




Volumn 147, Issue 4, 2002, Pages 543-551

Efficacy of 1400 W, a novel inhibitor of inducible nitric oxide synthase, in preventing interleukin-1β-induced suppression of pancreatic islet function in vitro and multiple low-dose streptozotocin-induced diabetes in vivo

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GLUCOSE; INSULIN; LIPOPOLYSACCHARIDE; N [3 (AMINOMETHYL)BENZYL]ACETAMIDINE; NITRATE; NITRIC OXIDE SYNTHASE INHIBITOR; NITRITE; RECOMBINANT INTERLEUKIN 1BETA; STREPTOZOCIN; UNCLASSIFIED DRUG;

EID: 0036773013     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1470543     Document Type: Article
Times cited : (34)

References (35)
  • 1
    • 0028982203 scopus 로고
    • Insulin-dependent diabetes mellitus as a β-cell targeted disease of immunoregulation
    • Bach J. Insulin-dependent diabetes mellitus as a β-cell targeted disease of immunoregulation. Journal of Autoimmunity 1995 8 439-463.
    • (1995) Journal of Autoimmunity , vol.8 , pp. 439-463
    • Bach, J.1
  • 2
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthases: Structure, function and inhibition
    • Alderton WK, Cooper CE & Knowles RG. Nitric oxide synthases: structure, function and inhibition. Biochemical Journal 2001 357 593-615.
    • (2001) Biochemical Journal , vol.357 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 3
    • 0028810841 scopus 로고
    • Isoforms of nitric oxide synthase. Properties, cellular distribution and expressional control
    • Förstermann U, Gath I, Schwarz P, Closs EI & Kleinert H. Isoforms of nitric oxide synthase. Properties, cellular distribution and expressional control. Biochemical Pharmacology 1995 50 1321-1332.
    • (1995) Biochemical Pharmacology , vol.50 , pp. 1321-1332
    • Förstermann, U.1    Gath, I.2    Schwarz, P.3    Closs, E.I.4    Kleinert, H.5
  • 4
    • 0026684463 scopus 로고
    • Type 1 (Insulin dependent) diabetes mellitus and nitric oxide
    • Kolb H & Kolb-Bachofen V. Type 1 (Insulin dependent) diabetes mellitus and nitric oxide. Diabetologia 1992 35 796-797.
    • (1992) Diabetologia , vol.35 , pp. 796-797
    • Kolb, H.1    Kolb-Bachofen, V.2
  • 5
    • 0026683354 scopus 로고
    • Does nitric oxide mediate autoimmune destruction of β-cells?
    • Corbett JA & McDaniel ML. Does nitric oxide mediate autoimmune destruction of β-cells? Diabetes 1992 41 897-903.
    • (1992) Diabetes , vol.41 , pp. 897-903
    • Corbett, J.A.1    McDaniel, M.L.2
  • 6
    • 0032171420 scopus 로고    scopus 로고
    • Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide
    • Wink D & Mitchell JB. Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide. Free Radical Biology and Medicine 1998 25 434-456.
    • (1998) Free Radical Biology and Medicine , vol.25 , pp. 434-456
    • Wink, D.1    Mitchell, J.B.2
  • 7
    • 0028900805 scopus 로고
    • Intraislet release of interleukin 1 inhibits β cell function by inducing β cell expression of inducible nitric oxide synthase
    • Corbett JA & McDaniel ML. Intraislet release of interleukin 1 inhibits β cell function by inducing β cell expression of inducible nitric oxide synthase. Journal of Experimental Medicine 1995 181 559-568.
    • (1995) Journal of Experimental Medicine , vol.181 , pp. 559-568
    • Corbett, J.A.1    McDaniel, M.L.2
  • 9
    • 0029989197 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase (iNOS) in pancreatic islets of non-obese diabetic mice: Identification of iNOS expressing cells and relationships to cytokines expressed in the islets
    • Rabinovitch A, Suarez-Pinzon W Sorensen O & Bleackley RC. Inducible nitric oxide synthase (iNOS) in pancreatic islets of non-obese diabetic mice: identification of iNOS expressing cells and relationships to cytokines expressed in the islets. Endocrinology 1996 137 2093-2099.
    • (1996) Endocrinology , vol.137 , pp. 2093-2099
    • Rabinovitch, A.1    Suarez-Pinzon, W.2    Sorensen, O.3    Bleackley, R.C.4
  • 10
    • 0027164671 scopus 로고
    • Transcription and translation of inducible nitric oxide synthase in the pancreas of prediabetic BB rats
    • Kleemann R, Rothe H, Kolb-Bachofen V, Me Q, Nathan CN, Martin S et al. Transcription and translation of inducible nitric oxide synthase in the pancreas of prediabetic BB rats. FEBS Letters 1993 328 9-12.
    • (1993) FEBS Letters , vol.328 , pp. 9-12
    • Kleemann, R.1    Rothe, H.2    Kolb-Bachofen, V.3    Me, Q.4    Nathan, C.N.5    Martin, S.6
  • 11
    • 0033041283 scopus 로고    scopus 로고
    • Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes
    • Flodström M, Tyrberg B, Eizirik DL & Sandler S. Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes. Diabetes 1999 42 706-713.
    • (1999) Diabetes , vol.42 , pp. 706-713
    • Flodström, M.1    Tyrberg, B.2    Eizirik, D.L.3    Sandler, S.4
  • 12
  • 15
    • 0014978068 scopus 로고
    • An improved fluorometric assay for DNA
    • Hinegardner RT. An improved fluorometric assay for DNA. Analytical Biochemistry 1971 39 197-201.
    • (1971) Analytical Biochemistry , vol.39 , pp. 197-201
    • Hinegardner, R.T.1
  • 16
    • 0018821862 scopus 로고
    • Long-term exposure of isolated pancreatic islets to mannoheptulose: Evidence for insulin degradation in the β-cell
    • Halban PA, Wollheim CB, Blondel B & Renold AE. Long-term exposure of isolated pancreatic islets to mannoheptulose: evidence for insulin degradation in the β-cell. Biochemical Pharmacology 1980 29 2625-2633.
    • (1980) Biochemical Pharmacology , vol.29 , pp. 2625-2633
    • Halban, P.A.1    Wollheim, C.B.2    Blondel, B.3    Renold, A.E.4
  • 20
    • 0030068610 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha and interferon-gamma inhibit insulin secretion and cause DNA damage in unweaned rat islets. Extent of nitric oxide involvement
    • Dunger A, Cunningham JM, Delaney CA, Lowe JE, Green MH, Bone AJ et al. Tumor necrosis factor-alpha and interferon-gamma inhibit insulin secretion and cause DNA damage in unweaned rat islets. Extent of nitric oxide involvement. Diabetes 1996 45 183-189.
    • (1996) Diabetes , vol.45 , pp. 183-189
    • Dunger, A.1    Cunningham, J.M.2    Delaney, C.A.3    Lowe, J.E.4    Green, M.H.5    Bone, A.J.6
  • 21
    • 0034808955 scopus 로고    scopus 로고
    • Cytokine-induced inhibition of insulin release from mouse pancreatic β-cells deficient in inducible nitric oxide synthase
    • Andersson AK, Flodström M & Sandler S. Cytokine-induced inhibition of insulin release from mouse pancreatic β-cells deficient in inducible nitric oxide synthase. Biochemical and Biophysical Research Communications 2001 281 396-403.
    • (2001) Biochemical and Biophysical Research Communications , vol.281 , pp. 396-403
    • Andersson, A.K.1    Flodström, M.2    Sandler, S.3
  • 22
    • 0027243274 scopus 로고
    • What are the types and cellular sources of free radicals in the pathogenesis of type 1 (insulin dependent) diabetes mellitus?
    • Mandrup-Poulsen T, Corbett JA, McDaniel ML, & Nerup J. What are the types and cellular sources of free radicals in the pathogenesis of type 1 (insulin dependent) diabetes mellitus? Diabetologia 1993 36 470-471.
    • (1993) Diabetologia , vol.36 , pp. 470-471
    • Mandrup-Poulsen, T.1    Corbett, J.A.2    McDaniel, M.L.3    Nerup, J.4
  • 25
    • 0000435224 scopus 로고
    • Suppression of low dose streptozotocin induced diabetes in mice by administration of a nitric oxide synthase inhibitor
    • Kolb H, Kiesel U, Kröncke K-D & Kolb-Bachofen V. Suppression of low dose streptozotocin induced diabetes in mice by administration of a nitric oxide synthase inhibitor. Life Sciences 1991 49 PL213-PL217.
    • (1991) Life Sciences , vol.49
    • Kolb, H.1    Kiesel, U.2    Kröncke, K.-D.3    Kolb-Bachofen, V.4
  • 26
    • 0028942484 scopus 로고
    • Administration of a nitric oxide synthase inhibitor does not suppress low-dose streptozotocin-induced diabetes in mice
    • Papaccio G, Esposito V, Latronico MV & Pisanti FA. Administration of a nitric oxide synthase inhibitor does not suppress low-dose streptozotocin-induced diabetes in mice. International Journal of Pancreatology 1995 17 63-68.
    • (1995) International Journal of Pancreatology , vol.17 , pp. 63-68
    • Papaccio, G.1    Esposito, V.2    Latronico, M.V.3    Pisanti, F.A.4
  • 27
    • 0027771348 scopus 로고
    • Aminoguanidine, an inhibitor of nitric oxide formation, fails to protect against insulitis and hyperglycemia induced by multiple low dose streptozotocin injections in mice
    • Holstad M & Sandler S. Aminoguanidine, an inhibitor of nitric oxide formation, fails to protect against insulitis and hyperglycemia induced by multiple low dose streptozotocin injections in mice. Autoimmunity 1993 15 311-314.
    • (1993) Autoimmunity , vol.15 , pp. 311-314
    • Holstad, M.1    Sandler, S.2
  • 28
    • 0028956376 scopus 로고
    • G-monomethyl-L-arginine on the onset of diabetes in the spontaneously diabetic BB rat
    • G-monomethyl-L-arginine on the onset of diabetes in the spontaneously diabetic BB rat. Diabetes 1995 44 360-364.
    • (1995) Diabetes , vol.44 , pp. 360-364
    • Wu, G.1
  • 30
    • 0027489210 scopus 로고
    • Nitric oxide production in islets of nonobese diabetic mice: Aminoguanidine-sensitive and -resistant stages in the immunological diabetic process
    • Corbett JA, Mikhael A, Shimizu J, Frederick K, Misko TP, McDaniel ML et al. Nitric oxide production in islets of nonobese diabetic mice: aminoguanidine-sensitive and -resistant stages in the immunological diabetic process. PNAS 1993 90 8992-8995.
    • (1993) PNAS , vol.90 , pp. 8992-8995
    • Corbett, J.A.1    Mikhael, A.2    Shimizu, J.3    Frederick, K.4    Misko, T.P.5    McDaniel, M.L.6
  • 31
    • 0001112593 scopus 로고
    • Pharmacokinetic and therapeutic analysis of aminoguanidine (AG) in non-obese diabetic (NOD) mice
    • Bowman M, Simell O. Look Z, Luchetta R & Atkinson M. Pharmacokinetic and therapeutic analysis of aminoguanidine (AG) in non-obese diabetic (NOD) mice. Diabetes 1994 43 (Suppl. 1) 235A.
    • (1994) Diabetes , vol.43 , Issue.SUPPL. 1
    • Bowman, M.1    Simell, O.2    Look, Z.3    Luchetta, R.4    Atkinson, M.5
  • 32
    • 0028819008 scopus 로고
    • Comparison of mRNA contents of interleukin-1β and nitric oxide synthase in pancreatic islets isolated from female and male nonobese diabetic mice
    • Welsh M, Welsh N, Bendtzen K, Mares J, Strandell E, Öberg C et al. Comparison of mRNA contents of interleukin-1β and nitric oxide synthase in pancreatic islets isolated from female and male nonobese diabetic mice. Diabetologia 1995 38 153-160.
    • (1995) Diabetologia , vol.38 , pp. 153-160
    • Welsh, M.1    Welsh, N.2    Bendtzen, K.3    Mares, J.4    Strandell, E.5    Öberg, C.6
  • 33
    • 0029989197 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase (iNOS) in pancreatic islets of non-obese diabetic mice: Identification of iNOS-expressing cells and relationships to cytokines expressed in the islets
    • Rabinovitch A, Suarez-Pinzon WL, Sorensen O & Bleackley RC. Inducible nitric oxide synthase (iNOS) in pancreatic islets of non-obese diabetic mice: identification of iNOS-expressing cells and relationships to cytokines expressed in the islets. Endocrinology 1996 137 2093-2099.
    • (1996) Endocrinology , vol.137 , pp. 2093-2099
    • Rabinovitch, A.1    Suarez-Pinzon, W.L.2    Sorensen, O.3    Bleackley, R.C.4
  • 34
    • 2142754958 scopus 로고    scopus 로고
    • Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry
    • McMillan K, Adler M, Auld DS, Baldwin JJ, Blasko E, Browne LJ et al. Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry. PNAS 2000 97 1506-1511.
    • (2000) PNAS , vol.97 , pp. 1506-1511
    • McMillan, K.1    Adler, M.2    Auld, D.S.3    Baldwin, J.J.4    Blasko, E.5    Browne, L.J.6
  • 35
    • 0028049833 scopus 로고
    • Major species differences between humans and rodents in the susceptibility to pancreatic β-cell injury
    • Eizirik DL, Pipeleers DG, Ling Z, Welsh N, Hellerström C & Andersson A. Major species differences between humans and rodents in the susceptibility to pancreatic β-cell injury. PNAS 1994 91 9253-9256.
    • (1994) PNAS , vol.91 , pp. 9253-9256
    • Eizirik, D.L.1    Pipeleers, D.G.2    Ling, Z.3    Welsh, N.4    Hellerström, C.5    Andersson, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.