Macrophage migration inhibitory factor deficiency protects pancreatic islets from palmitic acid-induced apoptosis

Immunology and Cell Biology

Volumn 90, Issue 7, 2012, Pages 688-698

  Saksida, Tamara ^a   Stosic Grujicic, Stanislava ^a   Timotijevic, Gordana ^a   Sandler, Stellan ^b   Stojanovic, Ivana ^a,b  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

apoptosis; b cells; macrophage migration inhibitory factor; obesity; palmitic acid; type 2 diabetes

Indexed keywords

ADENOSINE TRIPHOSPHATE; BIM PROTEIN; CASPASE; CASPASE 3; CASPASE 9; INSULIN; MACROPHAGE MIGRATION INHIBITION FACTOR; MESSENGER RNA; PALMITIC ACID; PROTEIN BAX; PROTEIN BCL 2; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; GENE DELETION; GLUCOSE INTOLERANCE; GLUCOSE OXIDATION; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; MALE; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PROTEIN EXPRESSION; PROTEIN SECRETION; RNA INTERFERENCE; WEIGHT GAIN;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOOD GLUCOSE; CASPASE 9; CELL LINE, TUMOR; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; INSULIN; ISLETS OF LANGERHANS; ISOXAZOLES; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PALMITIC ACID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRIGLYCERIDES; UP-REGULATION;

MUS;

EID: 84864859658     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2011.89     Document Type: Article

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