Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity

Journal of Medicinal Chemistry

Volumn 55, Issue 23, 2012, Pages 10729-10734

  Aboye, Teshome L ^a   Ha, Helen ^a   Majumder, Subhabrata ^b   Christ, Frauke ^c   Debyser, Zeger ^c   Shekhtman, Alexander ^b   Neamati, Nouri ^a   Camarero, Julio A ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; CYCLOTIDE; MCO CVX DERIVATIVE; RALTEGRAVIR; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CRYSTAL STRUCTURE; CYCLIZATION; DRUG ACTIVITY; DRUG DESIGN; DRUG STABILITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MOMORDICA COCHINCHINENSIS; SERUM; VIRUS ENTRY; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; CYCLOTIDES; HIV-1; MOLECULAR SEQUENCE DATA; RECEPTORS, CXCR4;

EID: 84871019068     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301468k     Document Type: Article

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