Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4)

Journal of Medicinal Chemistry

Volumn 55, Issue 3, 2012, Pages 977-994

  Choi, Won Tak ^a   Duggineni, Srinivas ^b   Xu, Yan ^b   Huang, Ziwei ^b   An, Jing ^b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 [(4 AMINOBUTYL)(2 BENZIMIDAZOLYLMETHYL)AMINO] 1,2,3,4 TETRAHYDROQUINOLINE; [5 (4 METHYL 1 PIPERAZINYL)] 2 [[[METHYL(5,6,7,8 TETRAHYDRO 8 QUINOLINYL)AMINO]METHYL]IMIDAZO[1,2 A]PYRIDIN 3 YL]METHANOL; ALPHA N ACETYLNONA DEXTRO ARGININE AMIDE; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; CTCE 9908; FC 131; FC 31; GSK 812397; KRH 1636; KRH 3955; N (6 AMINOHEXYL)GLYCYL N (3 GUANIDINOPROPYL)GLYCYL N (3 GUANIDINOPROPYL)GLYCYL N BENZYLGLYCYL N (3 GUANIDINOPROPYL)GLYCYL DEXTRO LYSYL DEXTRO LYSYL DEXTRO ARGINYL DEXTRO PROLINAMIDE; N [1,4,8,11 TETRAAZACYCLOTETRADECANYL 1,4 PHENYLENEBIS(METHYLENE)] 2 (AMINOMETHYL)PYRIDINE; N1,N4 DI 2 PYRIDINYL 1,4 BENZENEDIMETHANAMINE; PLERIXAFOR; POL 6326; POL 6362; RCP 168; T 140; T 22; TC 14012; UNCLASSIFIED DRUG; WZ 811;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ALLERGIC ASTHMA; ANTIVIRAL ACTIVITY; ARTICLE; CANCER CELL; CELL MIGRATION; CRYSTAL STRUCTURE; DIMERIZATION; DRUG BINDING SITE; DRUG BIOAVAILABILITY; DRUG RECEPTOR BINDING; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; LIGAND BINDING; MULTIPLE MYELOMA; NEURAL STEM CELL; NONHODGKIN LYMPHOMA; NONHUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); PROTEIN FUNCTION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; VIRUS ENTRY; VIRUS REPLICATION; VIRUS RESISTANCE;

ANIMALS; ANTI-HIV AGENTS; ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; ARTHRITIS, RHEUMATOID; ASTHMA; CELL MOVEMENT; DRUG DISCOVERY; HEMATOLOGIC NEOPLASMS; HIV-1; HUMANS; NEOPLASM INVASIVENESS; RECEPTORS, CXCR4; STEM CELLS; VIRUS INTERNALIZATION;

EID: 84863118617     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200568c     Document Type: Article

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