Understanding pharmacokinetic food effects using molecular dynamics simulation coupled with physiologically based pharmacokinetic modeling

Biopharmaceutics and Drug Disposition

Volumn 33, Issue 9, 2012, Pages 510-521

  Turner, David C ^a   Yin, Fuchang ^b   Kindt, James T ^b   Zhang, Hailing ^a  

^a MERCER UNIVERSITY   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

food effects; MD simulation; oral absorption; PBPK

Indexed keywords

ARTICLE; COLON; COMPUTER INTERFACE; DIFFUSION COEFFICIENT; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG FORMULATION; FOOD DRUG INTERACTION; GASTROINTESTINAL ABSORPTION; MICELLE; MICELLIZATION; MOLECULAR DYNAMICS; SIMULATION; SMALL INTESTINE; STOMACH;

ALGORITHMS; FOOD-DRUG INTERACTIONS; INTESTINAL ABSORPTION; INTESTINES; MICELLES; MODELS, BIOLOGICAL; MOLECULAR DYNAMICS SIMULATION; PHARMACEUTICAL PREPARATIONS;

EID: 84871017732     PISSN: 01422782     EISSN: 1099081X     Source Type: Journal    
DOI: 10.1002/bdd.1818     Document Type: Article

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