Leukotriene D4 stimulates the migration but not proliferation of endothelial cells mediated by the cysteinyl leukotriene cyslti receptor via the extracellular signal-regulated kinase pathway

Journal of Pharmacological Sciences

Volumn 109, Issue 2, 2009, Pages 285-292

  Yuan, Yu Mei ^a,b   Fang, San Hua ^a   Qian, Xiao Dong ^b   Liu, Li Ying ^a   Xu, Li Hua ^a   Shi, Wen Zhen ^a   Zhang, Li Hui ^c   Lu, Yun Bi ^a   Zhang, Wei Ping ^a   Wei, Er Qing ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b HUZHOU CENTRAL HOSPITAL   (China)

^c HANGZHOU NORMAL UNIVERSITY   (China)

Author keywords

Cysteinyl leukotriene receptor 1 (CysLTi); Endothelial cell; Extracellular signal regulated kinase (ERK) 1 2; Migration; Proliferation

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 6 (4 CARBOXYPHENYLTHIO) 5 HYDROXY 7,9,11,14 ICOSATETRAENOIC ACID; CELL PROTEIN; LEUKOTRIENE D4; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONTELUKAST; PROTEIN CYSLT1 RECEPTOR; PROTEIN CYSLT2 RECEPTOR; UNCLASSIFIED DRUG; 1,3 BUTADIENE DERIVATIVE; ACETIC ACID DERIVATIVE; DRUG DERIVATIVE; ENZYME INHIBITOR; LEUKOTRIENE D4 RECEPTOR; LEUKOTRIENE RECEPTOR; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MITOGEN ACTIVATED PROTEIN KINASE; NITRILE; QUINOLINE DERIVATIVE; SLOW REACTING SUBSTANCE;

ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; CELL LINE; CELL MOTION; METABOLISM;

ACETATES; BUTADIENES; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; ENDOTHELIAL CELLS; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LEUKOTRIENE ANTAGONISTS; LEUKOTRIENE D4; NITRILES; QUINOLINES; RECEPTORS, LEUKOTRIENE; SRS-A;

EID: 65449181610     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.08321FP     Document Type: Article

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