The Polymorphic Pseudokinase ROP5 Controls Virulence in Toxoplasma gondii by Regulating the Active Kinase ROP18

PLoS Pathogens

Volumn 8, Issue 11, 2012, Pages

  Behnke, Michael S ^a   Fentress, Sarah J ^a   Mashayekhi, Mona ^a   Li, Lucy X ^a   Taylor, Gregory A ^b,c   Sibley, L David ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c DURHAM VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GUANOSINE TRIPHOSPHATASE; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 6; LUCIFERASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN KINASE; PROTEIN KINASE ROP18; PSEUDOKINASE ROP5; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOLUMINESCENCE; CONTROLLED STUDY; ELISA KIT; ENZYME ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; MACROPHAGE; MICROARRAY ANALYSIS; MONOCYTE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE CLEARANCE; PARASITE VIRULENCE; PROTEIN EXPRESSIONS; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; TOXOPLASMA GONDII; WESTERN BLOTTING;

ANIMALS; ENZYME ACTIVATION; GENE DELETION; INTERFERON-GAMMA; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; TOXOPLASMA; TOXOPLASMOSIS;

MUS; TOXOPLASMA GONDII;

EID: 84870848874     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002992     Document Type: Article

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