Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 23, 2011, Pages 9631-9636

  Behnke, Michael S ^a   Khan, Asis ^a   Wootton, John C ^b   Dubey, Jitender P ^c   Tang, Keliang ^a   Sibley, L David ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

Copy number variation; Genetic mapping; Parasite; Quantitative trait locus mapping

Indexed keywords

PHOSPHOTRANSFERASE; PROTEIN SERINE THREONINE KINASE;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSOCIATION; ATTENUATION; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CATALYSIS; CELL LINEAGE; CLONE; CLUSTER ANALYSIS; CONTROLLED STUDY; FEMALE; GENE DISRUPTION; GENETIC CROSS; GENETICS; GENOME; HUMAN; HUMAN CELL; LETHALITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PHYLOGENY; POPULATION STRUCTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; QUANTITATIVE TRAIT LOCUS; TOXOPLASMA GONDII;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATS; CHROMOSOME MAPPING; FEMALE; GENE EXPRESSION PROFILING; GENETIC COMPLEMENTATION TEST; GENETIC VARIATION; GENOME, PROTOZOAN; MICE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MUTATION; PHYLOGENY; POLYMORPHISM, GENETIC; PROTEIN-SERINE-THREONINE KINASES; PROTOZOAN PROTEINS; QUANTITATIVE TRAIT LOCI; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECIES SPECIFICITY; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL; VIRULENCE;

TOXOPLASMA; TOXOPLASMA GONDII;

EID: 79959348595     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1015338108     Document Type: Article

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