메뉴 건너뛰기




Volumn 6, Issue 6, 2011, Pages

The IFN-γ-inducible GTPase, irga6, protects mice against toxoplasma gondii but not against plasmodium berghei and some other intracellular pathogens

(22)  Liesenfeld, Oliver a,j   Parvanova, Iana b,k   Zerrahn, Jens c,l   Han, Seong Ji a,m   Heinrich, Frederik a,n   Muñoz, Melba a,o   Kaiser, Frank c,p   Aebischer, Toni c,q   Buch, Thorsten b,r   Waisman, Ari b,e,r   Reichmann, Gaby d,s   Utermöhlen, Olaf b   von Stebut, Esther e   von Loewenich, Friederike D f   Bogdan, Christian f,g,t   Specht, Sabine h   Saeftel, Michael h,u   Hoerauf, Achim h   Mota, Maria M i   Könen Waisman, Stephanie b   more..


Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON GAMMA INDUCIBLE GUANOSINE TRIPHOSPHATASE; IRGA6 PROTEIN; PROTEIN; UNCLASSIFIED DRUG; GUANOSINE TRIPHOSPHATASE; IIGP1 PROTEIN, MOUSE;

EID: 79959228478     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020568     Document Type: Article
Times cited : (62)

References (56)
  • 3
    • 0030792813 scopus 로고    scopus 로고
    • Safe haven: the cell biology of nonfusogenic pathogen vacuoles
    • Sinai AP, Joiner KA, (1997) Safe haven: the cell biology of nonfusogenic pathogen vacuoles. Annu Rev Microbiol 51: 415-462.
    • (1997) Annu Rev Microbiol , vol.51 , pp. 415-462
    • Sinai, A.P.1    Joiner, K.A.2
  • 4
    • 33745327590 scopus 로고    scopus 로고
    • Cutting edge: dendritic cells are essential for in vivo IL-12 production and development of resistance against Toxoplasma gondii infection in mice
    • Liu CH, Fan YT, Dias A, Esper L, Corn RA, et al. (2006) Cutting edge: dendritic cells are essential for in vivo IL-12 production and development of resistance against Toxoplasma gondii infection in mice. J Immunol 177: 31-35.
    • (2006) J Immunol , vol.177 , pp. 31-35
    • Liu, C.H.1    Fan, Y.T.2    Dias, A.3    Esper, L.4    Corn, R.A.5
  • 5
    • 0031736936 scopus 로고    scopus 로고
    • Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection
    • Denkers EY, Gazzinelli RT, (1998) Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection. Clin Microbiol Rev 11: 569-588.
    • (1998) Clin Microbiol Rev , vol.11 , pp. 569-588
    • Denkers, E.Y.1    Gazzinelli, R.T.2
  • 6
    • 0037083175 scopus 로고    scopus 로고
    • Host resistance in the brain against Toxoplasma gondii
    • Suzuki Y, (2002) Host resistance in the brain against Toxoplasma gondii. J Infect Dis 185 (Suppl 1): S58-65.
    • (2002) J Infect Dis , vol.185 , Issue.SUPPL. 1 , pp. 58-65
    • Suzuki, Y.1
  • 7
    • 0024438401 scopus 로고
    • Importance of endogenous IFN-gamma for prevention of toxoplasmic encephalitis in mice
    • Suzuki Y, Conley FK, Remington JS, (1989) Importance of endogenous IFN-gamma for prevention of toxoplasmic encephalitis in mice. J Immunol 143: 2045-2050.
    • (1989) J Immunol , vol.143 , pp. 2045-2050
    • Suzuki, Y.1    Conley, F.K.2    Remington, J.S.3
  • 8
    • 0023895411 scopus 로고
    • Interferon-gamma: the major mediator of resistance against Toxoplasma gondii
    • Suzuki Y, Orellana MA, Schreiber RD, Remington JS, (1988) Interferon-gamma: the major mediator of resistance against Toxoplasma gondii. Science 240: 516-518.
    • (1988) Science , vol.240 , pp. 516-518
    • Suzuki, Y.1    Orellana, M.A.2    Schreiber, R.D.3    Remington, J.S.4
  • 9
    • 18144435991 scopus 로고    scopus 로고
    • Immune and inflammatory responses in the CNS: modulation by astrocytes
    • Aschner M, (1998) Immune and inflammatory responses in the CNS: modulation by astrocytes. Toxicol Lett 102-103: 283-287.
    • (1998) Toxicol Lett , vol.102-103 , pp. 283-287
    • Aschner, M.1
  • 10
    • 0033485283 scopus 로고    scopus 로고
    • Differential development of Toxoplasma gondii in neural cells
    • Fagard R, Van Tan H, Creuzet C, Pelloux H, (1999) Differential development of Toxoplasma gondii in neural cells. Parasitol Today 15: 504-507.
    • (1999) Parasitol Today , vol.15 , pp. 504-507
    • Fagard, R.1    van Tan, H.2    Creuzet, C.3    Pelloux, H.4
  • 12
    • 0037446524 scopus 로고    scopus 로고
    • TCR V beta 8+ T cells prevent development of toxoplasmic encephalitis in BALB/c mice genetically resistant to the disease
    • Kang H, Liesenfeld O, Remington JS, Claflin J, Wang X, et al. (2003) TCR V beta 8+ T cells prevent development of toxoplasmic encephalitis in BALB/c mice genetically resistant to the disease. J Immunol 170: 4254-4259.
    • (2003) J Immunol , vol.170 , pp. 4254-4259
    • Kang, H.1    Liesenfeld, O.2    Remington, J.S.3    Claflin, J.4    Wang, X.5
  • 13
    • 0036890722 scopus 로고    scopus 로고
    • Immunopathogenesis of cerebral toxoplasmosis
    • Suzuki Y, (2002) Immunopathogenesis of cerebral toxoplasmosis. J Infect Dis 186 (Suppl 2): S234-240.
    • (2002) J Infect Dis , vol.186 , Issue.SUPPL. 2 , pp. 234-240
    • Suzuki, Y.1
  • 14
  • 15
    • 34047256441 scopus 로고    scopus 로고
    • IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens
    • Taylor GA, (2007) IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens. Cell Microbiol 9: 1099-1107.
    • (2007) Cell Microbiol , vol.9 , pp. 1099-1107
    • Taylor, G.A.1
  • 16
    • 33744509713 scopus 로고    scopus 로고
    • The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage
    • Bekpen C, Hunn JP, Rohde C, Parvanova I, Guethlein L, et al. (2005) The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage. Genome Biol 6: R92.
    • (2005) Genome Biol , vol.6
    • Bekpen, C.1    Hunn, J.P.2    Rohde, C.3    Parvanova, I.4    Guethlein, L.5
  • 17
    • 0028835390 scopus 로고
    • Isolation of a gene encoding a developmentally regulated T cell-specific protein with a guanine nucleotide triphosphate-binding motif
    • Carlow DA, Marth J, Clark-Lewis I, Teh HS, (1995) Isolation of a gene encoding a developmentally regulated T cell-specific protein with a guanine nucleotide triphosphate-binding motif. J Immunol 154: 1724-1734.
    • (1995) J Immunol , vol.154 , pp. 1724-1734
    • Carlow, D.A.1    Marth, J.2    Clark-Lewis, I.3    Teh, H.S.4
  • 18
    • 0026552954 scopus 로고
    • The IRG-47 gene is IFN-gamma induced in B cells and encodes a protein with GTP-binding motifs
    • Gilly M, Wall R, (1992) The IRG-47 gene is IFN-gamma induced in B cells and encodes a protein with GTP-binding motifs. J Immunol 148: 3275-3281.
    • (1992) J Immunol , vol.148 , pp. 3275-3281
    • Gilly, M.1    Wall, R.2
  • 19
    • 0032534733 scopus 로고    scopus 로고
    • Two families of GTPases dominate the complex cellular response to interferon-gamma
    • Boehm U, Guethlein L, Klamp T, Ozbek K, Schaub A, et al. (1998) Two families of GTPases dominate the complex cellular response to interferon-gamma. J Immunol 161: 6715-6723.
    • (1998) J Immunol , vol.161 , pp. 6715-6723
    • Boehm, U.1    Guethlein, L.2    Klamp, T.3    Ozbek, K.4    Schaub, A.5
  • 20
    • 0028837679 scopus 로고
    • Identification of an endotoxin and IFN-inducible cDNA: possible identification of a novel protein family
    • Sorace JM, Johnson RJ, Howard DL, Drysdale BE, (1995) Identification of an endotoxin and IFN-inducible cDNA: possible identification of a novel protein family. J Leukoc Biol 58: 477-484.
    • (1995) J Leukoc Biol , vol.58 , pp. 477-484
    • Sorace, J.M.1    Johnson, R.J.2    Howard, D.L.3    Drysdale, B.E.4
  • 21
    • 0029832205 scopus 로고    scopus 로고
    • Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma
    • Taylor GA, Jeffers M, Largaespada DA, Jenkins NA, Copeland NG, et al. (1996) Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma. J Biol Chem 271: 20399-20405.
    • (1996) J Biol Chem , vol.271 , pp. 20399-20405
    • Taylor, G.A.1    Jeffers, M.2    Largaespada, D.A.3    Jenkins, N.A.4    Copeland, N.G.5
  • 22
    • 0036893663 scopus 로고    scopus 로고
    • The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and nonhematopoietic cellular compartments
    • Collazo CM, Yap GS, Hieny S, Caspar P, Feng CG, et al. (2002) The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and nonhematopoietic cellular compartments. Infect Immun 70: 6933-6939.
    • (2002) Infect Immun , vol.70 , pp. 6933-6939
    • Collazo, C.M.1    Yap, G.S.2    Hieny, S.3    Caspar, P.4    Feng, C.G.5
  • 23
    • 0034681123 scopus 로고    scopus 로고
    • Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP
    • Taylor GA, Collazo CM, Yap GS, Nguyen K, Gregorio TA, et al. (2000) Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP. Proc Natl Acad Sci U S A 97: 751-755.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 751-755
    • Taylor, G.A.1    Collazo, C.M.2    Yap, G.S.3    Nguyen, K.4    Gregorio, T.A.5
  • 24
    • 79951552359 scopus 로고    scopus 로고
    • The Immunity-Related GTPases in mammals - a fast evolving cell-autonomous resistance system against intracellular pathogens
    • Hunn JP, Feng CG, Sher A, Howard JC, (2011) The Immunity-Related GTPases in mammals- a fast evolving cell-autonomous resistance system against intracellular pathogens. Mammalian Genome 22: 43-54.
    • (2011) Mammalian Genome , vol.22 , pp. 43-54
    • Hunn, J.P.1    Feng, C.G.2    Sher, A.3    Howard, J.C.4
  • 25
    • 77957687715 scopus 로고    scopus 로고
    • The Mouse Resistance Protein Irgm1 (LRG-47): A regulator or an effector of pathogen defense?
    • Hunn JP, Howard JC, (2010) The Mouse Resistance Protein Irgm1 (LRG-47): A regulator or an effector of pathogen defense? PLoS Pathog 6: e1001008.
    • (2010) PLoS Pathog , vol.6
    • Hunn, J.P.1    Howard, J.C.2
  • 26
    • 49649126253 scopus 로고    scopus 로고
    • Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases
    • Martens S, Parvanova I, Zerrahn J, Griffiths G, Schell G, et al. (2005) Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases. PLoS Pathog 1: e24.
    • (2005) PLoS Pathog , vol.1
    • Martens, S.1    Parvanova, I.2    Zerrahn, J.3    Griffiths, G.4    Schell, G.5
  • 27
    • 77954430293 scopus 로고    scopus 로고
    • Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole
    • Khaminets A, Hunn JP, Konen-Waisman S, Zhao YO, Preukschat D, et al. (2010) Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole. Cell Microbiol 12: 939-961.
    • (2010) Cell Microbiol , vol.12 , pp. 939-961
    • Khaminets, A.1    Hunn, J.P.2    Konen-Waisman, S.3    Zhao, Y.O.4    Preukschat, D.5
  • 28
    • 31344463467 scopus 로고    scopus 로고
    • Transcriptional responses in mouse lungs induced by vaccination with Mycobacterium bovis BCG and infection with Mycobacterium tuberculosis
    • Mollenkopf HJ, Hahnke K, Kaufmann SH, (2006) Transcriptional responses in mouse lungs induced by vaccination with Mycobacterium bovis BCG and infection with Mycobacterium tuberculosis. Microbes Infect 8: 136-144.
    • (2006) Microbes Infect , vol.8 , pp. 136-144
    • Mollenkopf, H.J.1    Hahnke, K.2    Kaufmann, S.H.3
  • 29
    • 0035669096 scopus 로고    scopus 로고
    • A lipophosphoglycan-independent method for isolation of infective Leishmania metacyclic promastigotes by density gradient centrifugation
    • Spath GF, Beverley SM, (2001) A lipophosphoglycan-independent method for isolation of infective Leishmania metacyclic promastigotes by density gradient centrifugation. Exp Parasitol 99: 97-103.
    • (2001) Exp Parasitol , vol.99 , pp. 97-103
    • Spath, G.F.1    Beverley, S.M.2
  • 30
    • 0041488744 scopus 로고    scopus 로고
    • Interleukin 1alpha promotes Th1 differentiation and inhibits disease progression in Leishmania major-susceptible BALB/c mice
    • Von Stebut E, Ehrchen JM, Belkaid Y, Kostka SL, Molle K, et al. (2003) Interleukin 1alpha promotes Th1 differentiation and inhibits disease progression in Leishmania major-susceptible BALB/c mice. J Exp Med 198: 191-199.
    • (2003) J Exp Med , vol.198 , pp. 191-199
    • von Stebut, E.1    Ehrchen, J.M.2    Belkaid, Y.3    Kostka, S.L.4    Molle, K.5
  • 31
    • 0030798399 scopus 로고    scopus 로고
    • Antigenic diversity of granulocytic Ehrlichia isolates from humans in Wisconsin and New York and a horse in California
    • Asanovich KM, Bakken JS, Madigan JE, Aguero-Rosenfeld M, Wormser GP, et al. (1997) Antigenic diversity of granulocytic Ehrlichia isolates from humans in Wisconsin and New York and a horse in California. J Infect Dis 176: 1029-1034.
    • (1997) J Infect Dis , vol.176 , pp. 1029-1034
    • Asanovich, K.M.1    Bakken, J.S.2    Madigan, J.E.3    Aguero-Rosenfeld, M.4    Wormser, G.P.5
  • 32
    • 3442897088 scopus 로고    scopus 로고
    • Control of Anaplasma phagocytophilum, an obligate intracellular pathogen, in the absence of inducible nitric oxide synthase, phagocyte NADPH oxidase, tumor necrosis factor, Toll-like receptor (TLR)2 and TLR4, or the TLR adaptor molecule MyD88
    • von Loewenich FD, Scorpio DG, Reischl U, Dumler JS, Bogdan C, (2004) Control of Anaplasma phagocytophilum, an obligate intracellular pathogen, in the absence of inducible nitric oxide synthase, phagocyte NADPH oxidase, tumor necrosis factor, Toll-like receptor (TLR)2 and TLR4, or the TLR adaptor molecule MyD88. Eur J Immunol 34: 1789-1797.
    • (2004) Eur J Immunol , vol.34 , pp. 1789-1797
    • von Loewenich, F.D.1    Scorpio, D.G.2    Reischl, U.3    Dumler, J.S.4    Bogdan, C.5
  • 33
    • 64249144461 scopus 로고    scopus 로고
    • A small molecule inhibitor of signal peptide peptidase inhibits Plasmodium development in the liver and decreases malaria severity
    • Parvanova I, Epiphanio S, Fauq A, Golde TE, Prudencio M, et al. (2009) A small molecule inhibitor of signal peptide peptidase inhibits Plasmodium development in the liver and decreases malaria severity. PLoS One 4: e5078.
    • (2009) PLoS One , vol.4
    • Parvanova, I.1    Epiphanio, S.2    Fauq, A.3    Golde, T.E.4    Prudencio, M.5
  • 34
    • 4043065683 scopus 로고    scopus 로고
    • Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis
    • Martens S, Sabel K, Lange R, Uthaiah R, Wolf E, et al. (2004) Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis. J Immunol 173: 2594-2606.
    • (2004) J Immunol , vol.173 , pp. 2594-2606
    • Martens, S.1    Sabel, K.2    Lange, R.3    Uthaiah, R.4    Wolf, E.5
  • 35
    • 0028269705 scopus 로고
    • Demonstration of heat-shock protein 70 in the sporozoite stage of malaria parasites
    • Tsuji M, Mattei D, Nussenzweig RS, Eichinger D, Zavala F, (1994) Demonstration of heat-shock protein 70 in the sporozoite stage of malaria parasites. Parasitol Res 80: 16-21.
    • (1994) Parasitol Res , vol.80 , pp. 16-21
    • Tsuji, M.1    Mattei, D.2    Nussenzweig, R.S.3    Eichinger, D.4    Zavala, F.5
  • 36
    • 23044530313 scopus 로고    scopus 로고
    • Studying trafficking of intracellular pathogens in antigen presenting cells
    • In: Zychlinski A, Sansonnetti P, editors, New York, Academic Press
    • Schaible UE, Kaufmann SH, (2002) Studying trafficking of intracellular pathogens in antigen presenting cells. In: Zychlinski A, Sansonnetti P, editors. Methods in Microbiology New York Academic Press pp. 343-360.
    • (2002) Methods in Microbiology , pp. 343-360
    • Schaible, U.E.1    Kaufmann, S.H.2
  • 37
  • 38
    • 9644270367 scopus 로고    scopus 로고
    • Atovaquone maintenance therapy prevents reactivation of toxoplasmic encephalitis in a murine model of reactivated toxoplasmosis
    • Dunay IR, Heimesaat MM, Bushrab FN, Muller RH, Stocker H, et al. (2004) Atovaquone maintenance therapy prevents reactivation of toxoplasmic encephalitis in a murine model of reactivated toxoplasmosis. Antimicrob Agents Chemother 48: 4848-4854.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 4848-4854
    • Dunay, I.R.1    Heimesaat, M.M.2    Bushrab, F.N.3    Muller, R.H.4    Stocker, H.5
  • 39
    • 0032534733 scopus 로고    scopus 로고
    • Two families of GTPases dominate the complex cellular response to IFN-gamma
    • Boehm U, Guethlein L, Klamp T, Ozbek K, Schaub A, et al. (1998) Two families of GTPases dominate the complex cellular response to IFN-gamma. J Immunol 161: 6715-6723.
    • (1998) J Immunol , vol.161 , pp. 6715-6723
    • Boehm, U.1    Guethlein, L.2    Klamp, T.3    Ozbek, K.4    Schaub, A.5
  • 40
    • 69449108432 scopus 로고    scopus 로고
    • A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1) in mouse liver
    • Zeng J, Parvanova IA, Howard JC, (2009) A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1) in mouse liver. PLoS ONE 4: e6787.
    • (2009) PLoS ONE , vol.4
    • Zeng, J.1    Parvanova, I.A.2    Howard, J.C.3
  • 41
    • 33750140518 scopus 로고    scopus 로고
    • The silent path to thousands of merozoites: the Plasmodium liver stage. Nat Rev Microbiol
    • Prudencio M, Rodriguez A, Mota MM, (2006) The silent path to thousands of merozoites: the Plasmodium liver stage. Nat Rev Microbiol. 4 (11): 849-56.
    • (2006) , vol.4 , Issue.11 , pp. 849-856
    • Prudencio, M.1    Rodriguez, A.2    Mota, M.M.3
  • 42
    • 44449088023 scopus 로고    scopus 로고
    • Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10
    • Coers J, Bernstein-Hanley I, Grotsky D, Parvanova I, Howard JC, et al. (2008) Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10. J Immunol 180: 6237-6245.
    • (2008) J Immunol , vol.180 , pp. 6237-6245
    • Coers, J.1    Bernstein-Hanley, I.2    Grotsky, D.3    Parvanova, I.4    Howard, J.C.5
  • 44
    • 84864290306 scopus 로고    scopus 로고
    • IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy
    • Al-Zeer MA, Al-Younes HM, Braun PR, Zerrahn J, Meyer TF, (2009) IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy. PLoS ONE 4: e4588.
    • (2009) PLoS ONE , vol.4
    • Al-Zeer, M.A.1    Al-Younes, H.M.2    Braun, P.R.3    Zerrahn, J.4    Meyer, T.F.5
  • 45
    • 61449117883 scopus 로고    scopus 로고
    • Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death
    • Zhao YO, Khaminets A, Hunn JP, Howard JC, (2009) Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death. PLoS Pathog 5: e1000288.
    • (2009) PLoS Pathog , vol.5
    • Zhao, Y.O.1    Khaminets, A.2    Hunn, J.P.3    Howard, J.C.4
  • 46
    • 65449163019 scopus 로고    scopus 로고
    • Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages
    • Zhao Y, Ferguson DJ, Wilson DC, Howard JC, Sibley LD, et al. (2009) Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages. J Immunol 182 (6): 3775-81.
    • (2009) J Immunol , vol.182 , Issue.6 , pp. 3775-3781
    • Zhao, Y.1    Ferguson, D.J.2    Wilson, D.C.3    Howard, J.C.4    Sibley, L.D.5
  • 47
    • 78650194774 scopus 로고    scopus 로고
    • Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence.
    • Fentress SJ, Behnke MS, Dunay IR, Mashayekhi M, Rommereim LM, et al. (2010) Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence.Cell Host Microbe Dec 16;8 (6): 484-95.
    • (2010) Cell Host Microbe Dec 16 , vol.8 , Issue.6 , pp. 484-495
    • Fentress, S.J.1    Behnke, M.S.2    Dunay, I.R.3    Mashayekhi, M.4    Rommereim, L.M.5
  • 48
    • 78650210471 scopus 로고    scopus 로고
    • Phosphorylation of IRG resistance proteins is an evasion strategy for virulent T. gondii strains
    • doi:10.1371/journal.pbio.1000576
    • Steinfeldt T, Könen-Waisman S, Tong L, Pawlowski N, Lamkemeyer T, et al. (2010) Phosphorylation of IRG resistance proteins is an evasion strategy for virulent T. gondii strains. PLoS Biology 8 (12): e1000576 doi:10.1371/journal.pbio.1000576.
    • (2010) PLoS Biology , vol.8 , Issue.12
    • Steinfeldt, T.1    Könen-Waisman, S.2    Tong, L.3    Pawlowski, N.4    Lamkemeyer, T.5
  • 49
    • 0035898464 scopus 로고    scopus 로고
    • Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection
    • Collazo CM, Yap GS, Sempowski GD, Lusby KC, Tessarollo L, et al. (2001) Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection. J Exp Med 194: 181-188.
    • (2001) J Exp Med , vol.194 , pp. 181-188
    • Collazo, C.M.1    Yap, G.S.2    Sempowski, G.D.3    Lusby, K.C.4    Tessarollo, L.5
  • 50
    • 53549109432 scopus 로고    scopus 로고
    • Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii
    • Hunn JP, Koenen-Waisman S, Papic N, Schroeder N, Pawlowski N, et al. (2008) Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii. Embo J 27: 2495-2509.
    • (2008) Embo J , vol.27 , pp. 2495-2509
    • Hunn, J.P.1    Koenen-Waisman, S.2    Papic, N.3    Schroeder, N.4    Pawlowski, N.5
  • 51
    • 61449240361 scopus 로고    scopus 로고
    • Modeling infectious disease in mice: co-adaptation and the role of host-specific IFNgamma responses
    • Coers J, Starnbach MN, Howard JC, (2009) Modeling infectious disease in mice: co-adaptation and the role of host-specific IFNgamma responses. PLoS Pathog 5: e1000333.
    • (2009) PLoS Pathog , vol.5
    • Coers, J.1    Starnbach, M.N.2    Howard, J.C.3
  • 52
    • 0036533657 scopus 로고    scopus 로고
    • The IFN-inducible Golgi- and endoplasmic reticulum- associated 47-kDa GTPase IIGP is transiently expressed during listeriosis
    • Zerrahn J, Schaible UE, Brinkmann V, Guhlich U, Kaufmann SH, (2002) The IFN-inducible Golgi- and endoplasmic reticulum- associated 47-kDa GTPase IIGP is transiently expressed during listeriosis. J Immunol 168: 3428-3436.
    • (2002) J Immunol , vol.168 , pp. 3428-3436
    • Zerrahn, J.1    Schaible, U.E.2    Brinkmann, V.3    Guhlich, U.4    Kaufmann, S.H.5
  • 53
    • 0023150598 scopus 로고
    • HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells
    • Hooper M, Hardy K, Handyside A, Hunter S, Monk M, (1987) HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells. Nature 326: 292-295.
    • (1987) Nature , vol.326 , pp. 292-295
    • Hooper, M.1    Hardy, K.2    Handyside, A.3    Hunter, S.4    Monk, M.5
  • 54
    • 0036859318 scopus 로고    scopus 로고
    • DNA polymerase kappa deficiency does not affect somatic hypermutation in mice
    • Schenten D, Gerlach VL, Guo C, Velasco-Miguel S, Hladik CL, et al. (2002) DNA polymerase kappa deficiency does not affect somatic hypermutation in mice. Eur J Immunol 32: 3152-3160.
    • (2002) Eur J Immunol , vol.32 , pp. 3152-3160
    • Schenten, D.1    Gerlach, V.L.2    Guo, C.3    Velasco-Miguel, S.4    Hladik, C.L.5
  • 56
    • 0029566108 scopus 로고
    • A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
    • Schwenk F, Baron U, Rajewsky K, (1995) A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res 23: 5080-5081.
    • (1995) Nucleic Acids Res , vol.23 , pp. 5080-5081
    • Schwenk, F.1    Baron, U.2    Rajewsky, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.