Crystal structures of nitroalkane oxidase: Insights into the reaction mechanism from a covalent complex of the flavoenzyme trapped during turnover

Biochemistry

Volumn 45, Issue 4, 2006, Pages 1138-1150

  Nagpal, Akanksha ^a   Valley, Michael P ^b   Fitzpatrick, Paul F ^b   Orville, Allen M ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; CARRIER CONCENTRATION; CRYSTAL STRUCTURE; DEHYDROGENATION; ENZYMES; HYDROPHOBICITY; KETONES; OXIDATION; PROTEINS; SUBSTRATES;

ACYL-COA DEHYDROGENASE (ACAD); NITROALKANE OXIDASE (NAO); SPACE GROUPS; SUBSTRATE MOLECULES;

ENZYME KINETICS;

ACYL COENZYME A DEHYDROGENASE; ALDEHYDE; ASPARTIC ACID; ETHANE; FLAVINE ADENINE NUCLEOTIDE; FLAVOPROTEIN; GLUTAMIC ACID; HYDROGEN PEROXIDE; KETONE; N5 (2 NITROBUTYL) 1,5 DIHYDROFLAVINE ADENINE NUCLEOTIDE; NITRITE; NITROALKANE; NITROALKANE OXIDASE; NITROETHANE; OXIDOREDUCTASE; OXIDOREDUCTASE INHIBITOR; PROTON; SPERMINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CATALYST; COVALENT BOND; CRYSTAL STRUCTURE; ELECTRON; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME METABOLISM; ENZYME SUBSTRATE COMPLEX; FUSARIUM OXYSPORUM; HYDROGEN BOND; HYDROPHOBICITY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; REACTION ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

ACYL-COA DEHYDROGENASES; AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLIZATION; DIOXYGENASES; ENZYME STABILITY; ESCHERICHIA COLI; FLAVIN-ADENINE DINUCLEOTIDE; FLAVINS; FLAVOPROTEINS; FUSARIUM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SPERMINE; SUBSTRATE SPECIFICITY;

FUSARIUM OXYSPORUM;

EID: 31544467044     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051966w     Document Type: Article

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