Stereochemical Studies of the Type II Isopentenyl Diphosphate-Dimethylallyl Diphosphate Isomerase Implicate the FMN Coenzyme in Substrate Protonation

ChemBioChem

Volumn 13, Issue 1, 2012, Pages 42-46

  Calveras, Jordi ^a   Thibodeaux, Christopher J ^a   Mansoorabadi, Steven O ^a   Liu, Hung wen ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Chiral methyl analysis; Enzyme catalysis; FMN; Proton inventory; Reaction mechanisms

Indexed keywords

DIMETHYLALLYL DIPHOSPHATE ISOMERASE; FLAVINE MONONUCLEOTIDE; ISOMERASE; ISOPENTENYL DIPHOSPHATE DELTA ISOMERASE; UNCLASSIFIED DRUG;

ARTICLE; BIOCATALYST; CHIRALITY; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTON TRANSPORT; STEADY STATE; STEREOCHEMISTRY; TURNOVER TIME;

BIOCATALYSIS; CARBON-CARBON DOUBLE BOND ISOMERASES; COENZYMES; FLAVIN MONONUCLEOTIDE; LUCIFERASES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTONS; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 84155174687     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201100694     Document Type: Article

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