Epitope-specific CD8+ T cells play a differential pathogenic role in the development of a viral disease model for multiple sclerosis

Journal of Virology

Volumn 86, Issue 24, 2012, Pages 13717-13728

  Myoung, Jinjong ^a,b   Kang, Hyun Seok ^a   Hou, Wanqiu ^a   Meng, Liping ^a   Dal Canto, Mauro C ^a   Kim, Byung S ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 22; MESSENGER RNA; PROTEIN VP3; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RESPONSE; ENCEPHALOMYELITIS; FEMALE; IMMUNOCYTOTOXICITY; IMMUNOPATHOGENESIS; IMMUNOSTIMULATION; INTERFERON PRODUCTION; MULTIPLE SCLEROSIS; MURINE ENCEPHALOMYELITIS VIRUS; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; VIRUS LOAD; VIRUS REPLICATION;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; CRICETINAE; DISEASE MODELS, ANIMAL; EPITOPES; MICE; MULTIPLE SCLEROSIS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VIRUS DISEASES; VIRUS REPLICATION;

MUS; THEILER'S ENCEPHALOMYELITIS VIRUS;

EID: 84870664698     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01733-12     Document Type: Article

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