-
1
-
-
8144228952
-
Friends or foes: Bipolar effects of the tumour stroma in cancer
-
Mueller, M. M., and N. E. Fusenig. 2004. Friends or foes: bipolar effects of the tumour stroma in cancer. Nat. Rev. Cancer 4: 839-849.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 839-849
-
-
Mueller, M.M.1
Fusenig, N.E.2
-
2
-
-
33645739790
-
Tumor stroma and regulation of cancer development
-
Tlsty, T. D., and L. M. Coussens. 2006. Tumor stroma and regulation of cancer development. Annu. Rev. Pathol. 1: 119-150.
-
(2006)
Annu. Rev. Pathol.
, vol.1
, pp. 119-150
-
-
Tlsty, T.D.1
Coussens, L.M.2
-
3
-
-
51349092937
-
Tumor stroma as a target in cancer
-
Ahmed, F., J. C. Steele, J. M. Herbert, N. M. Steven, and R. Bicknell. 2008. Tumor stroma as a target in cancer. Curr. Cancer Drug Targets 8: 447-453.
-
(2008)
Curr. Cancer Drug Targets
, vol.8
, pp. 447-453
-
-
Ahmed, F.1
Steele, J.C.2
Herbert, J.M.3
Steven, N.M.4
Bicknell, R.5
-
4
-
-
44349150012
-
Inhibitory B7-family molecules in the tumour microenvironment
-
Zou, W., and L. Chen. 2008. Inhibitory B7-family molecules in the tumour microenvironment. Nat. Rev. Immunol. 8: 467-477.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 467-477
-
-
Zou, W.1
Chen, L.2
-
5
-
-
33747029250
-
Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment
-
Budhu, A., M. Forgues, Q. H. Ye, H. L. Jia, P. He, K. A. Zanetti, U. S. Kammula, Y. Chen, L. X. Qin, Z. Y. Tang, and X. W. Wang. 2006. Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment. Cancer Cell 10: 99-111.
-
(2006)
Cancer Cell
, vol.10
, pp. 99-111
-
-
Budhu, A.1
Forgues, M.2
Ye, Q.H.3
Jia, H.L.4
He, P.5
Zanetti, K.A.6
Kammula, U.S.7
Chen, Y.8
Qin, L.X.9
Tang, Z.Y.10
Wang, X.W.11
-
6
-
-
67449110979
-
Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1
-
Kuang, D. M., Q. Zhao, C. Peng, J. Xu, J. P. Zhang, C. Wu, and L. Zheng. 2009. Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1. J. Exp. Med. 206: 1327-1337.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1327-1337
-
-
Kuang, D.M.1
Zhao, Q.2
Peng, C.3
Xu, J.4
Zhang, J.P.5
Wu, C.6
Zheng, L.7
-
7
-
-
73449111925
-
Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells
-
Kuang, D. M., C. Peng, Q. Zhao, Y. Wu, M. S. Chen, and L. Zheng. 2010. Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells. Hepatology 51: 154-164.
-
(2010)
Hepatology
, vol.51
, pp. 154-164
-
-
Kuang, D.M.1
Peng, C.2
Zhao, Q.3
Wu, Y.4
Chen, M.S.5
Zheng, L.6
-
9
-
-
64549108462
-
Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients
-
Zhang, J. P., J. Yan, J. Xu, X. H. Pang, M. S. Chen, L. Li, C. Wu, S. P. Li, and L. Zheng. 2009. Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients. J. Hepatol. 50: 980-989.
-
(2009)
J. Hepatol.
, vol.50
, pp. 980-989
-
-
Zhang, J.P.1
Yan, J.2
Xu, J.3
Pang, X.H.4
Chen, M.S.5
Li, L.6
Wu, C.7
Li, S.P.8
Zheng, L.9
-
10
-
-
67650495415
-
IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
-
Wang, L., T. Yi, M. Kortylewski, D. M. Pardoll, D. Zeng, and H. Yu. 2009. IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J. Exp. Med. 206: 1457-1464.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1457-1464
-
-
Wang, L.1
Yi, T.2
Kortylewski, M.3
Pardoll, D.M.4
Zeng, D.5
Yu, H.6
-
11
-
-
69849107597
-
Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments
-
Kryczek, I., M. Banerjee, P. Cheng, L. Vatan, W. Szeliga, S. Wei, E. Huang, E. Finlayson, D. Simeone, T. H. Welling, et al. 2009. Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood 114: 1141-1149.
-
(2009)
Blood
, vol.114
, pp. 1141-1149
-
-
Kryczek, I.1
Banerjee, M.2
Cheng, P.3
Vatan, L.4
Szeliga, W.5
Wei, S.6
Huang, E.7
Finlayson, E.8
Simeone, D.9
Welling, T.H.10
-
12
-
-
51549091457
-
Tumor-educated tolerogenic dendritic cells induce CD3epsilon down-regulation and apoptosis of T cells through oxygen-dependent pathways
-
Kuang, D. M., Q. Zhao, J. Xu, J. P. Yun, C. Wu, and L. Zheng. 2008. Tumor-educated tolerogenic dendritic cells induce CD3epsilon down-regulation and apoptosis of T cells through oxygen-dependent pathways. J. Immunol. 181: 3089-3098.
-
(2008)
J. Immunol.
, vol.181
, pp. 3089-3098
-
-
Kuang, D.M.1
Zhao, Q.2
Xu, J.3
Yun, J.P.4
Wu, C.5
Zheng, L.6
-
13
-
-
34347241756
-
Human macrophages promote the motility and invasiveness of osteopontin-knockdown tumor cells
-
Cheng, J., D. H. Huo, D. M. Kuang, J. Yang, L. Zheng, and S. M. Zhuang. 2007. Human macrophages promote the motility and invasiveness of osteopontin-knockdown tumor cells. Cancer Res. 67: 5141-5147.
-
(2007)
Cancer Res.
, vol.67
, pp. 5141-5147
-
-
Cheng, J.1
Huo, D.H.2
Kuang, D.M.3
Yang, J.4
Zheng, L.5
Zhuang, S.M.6
-
14
-
-
34547113798
-
Tumor-derived hyaluronan induces formation of immunosuppressive macrophages through transient early activation of monocytes
-
Kuang, D. M., Y. Wu, N. Chen, J. Cheng, S. M. Zhuang, and L. Zheng. 2007. Tumor-derived hyaluronan induces formation of immunosuppressive macrophages through transient early activation of monocytes. Blood 110: 587-595.
-
(2007)
Blood
, vol.110
, pp. 587-595
-
-
Kuang, D.M.1
Wu, Y.2
Chen, N.3
Cheng, J.4
Zhuang, S.M.5
Zheng, L.6
-
15
-
-
0036172653
-
Detection of mycoplasma in leukemia-lymphoma cell lines using polymerase chain reaction
-
Uphoff, C. C., and H. G. Drexler. 2002. Detection of mycoplasma in leukemia-lymphoma cell lines using polymerase chain reaction. Leukemia 16: 289-293.
-
(2002)
Leukemia
, vol.16
, pp. 289-293
-
-
Uphoff, C.C.1
Drexler, H.G.2
-
16
-
-
42649115767
-
TH17 cells in development: An updated view of their molecular identity and genetic programming
-
Dong, C. 2008. TH17 cells in development: an updated view of their molecular identity and genetic programming. Nat. Rev. Immunol. 8: 337-348.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 337-348
-
-
Dong, C.1
-
18
-
-
44049104564
-
H-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
-
H-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat. Immunol. 9: 641-649.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
19
-
-
54549100120
-
Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells
-
Zhang, F., G. Meng, and W. Strober. 2008. Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells. Nat. Immunol. 9: 1297-1306.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1297-1306
-
-
Zhang, F.1
Meng, G.2
Strober, W.3
-
20
-
-
70350459594
-
The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity
-
Klotz, L., S. Burgdorf, I. Dani, K. Saijo, J. Flossdorf, S. Hucke, J. Alferink, N. Nowak, and M. Beyer, G. Mayer et al. 2009. The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity. J. Exp. Med. 206: 2079-2089.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2079-2089
-
-
Klotz, L.1
Burgdorf, S.2
Dani, I.3
Saijo, K.4
Flossdorf, J.5
Hucke, S.6
Alferink, J.7
Nowak, N.8
Beyer, M.9
Mayer, G.10
-
21
-
-
0035257205
-
Lymphocyte traffic control by chemokines
-
Moser, B., and P. Loetscher. 2001. Lymphocyte traffic control by chemokines. Nat. Immunol. 2: 123-128.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 123-128
-
-
Moser, B.1
Loetscher, P.2
-
22
-
-
5644277476
-
Interleukin-17 family members and inflammation
-
Kolls, J. K., and A. Lindén. 2004. Interleukin-17 family members and inflammation. Immunity 21: 467-476.
-
(2004)
Immunity
, vol.21
, pp. 467-476
-
-
Kolls, J.K.1
Lindén, A.2
-
23
-
-
38849187386
-
IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation
-
Ma, H. L., S. Liang, J. Li, L. Napierata, T. Brown, S. Benoit, M. Senices, D. Gill, K. Dunussi-Joannopoulos, M. Collins, et al. 2008. IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. J. Clin. Invest. 118: 597-607.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 597-607
-
-
Ma, H.L.1
Liang, S.2
Li, J.3
Napierata, L.4
Brown, T.5
Benoit, S.6
Senices, M.7
Gill, D.8
Dunussi-Joannopoulos, K.9
Collins, M.10
-
24
-
-
58149269348
-
Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis
-
Kim, S., H. Takahashi, W. W. Lin, P. Descargues, S. Grivennikov, Y. Kim, J. L. Luo, and M. Karin. 2009. Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis. Nature 457: 102-106.
-
(2009)
Nature
, vol.457
, pp. 102-106
-
-
Kim, S.1
Takahashi, H.2
Lin, W.W.3
Descargues, P.4
Grivennikov, S.5
Kim, Y.6
Luo, J.L.7
Karin, M.8
-
25
-
-
34247464330
-
Swords into plowshares: IL-23 repurposes tumor immune surveillance
-
Langowski, J. L., R. A. Kastelein, and M. Oft. 2007. Swords into plowshares: IL-23 repurposes tumor immune surveillance. Trends Immunol. 28: 207-212.
-
(2007)
Trends Immunol.
, vol.28
, pp. 207-212
-
-
Langowski, J.L.1
Kastelein, R.A.2
Oft, M.3
-
27
-
-
73349101421
-
Tc17 CD8 T cells: Functional plasticity and subset diversity
-
Yen, H. R., T. J. Harris, S. Wada, J. F. Grosso, D. Getnet, M. V. Goldberg, K. L. Liang, T. C. Bruno, K. J. Pyle, S. L. Chan, et al. 2009. Tc17 CD8 T cells: functional plasticity and subset diversity. J. Immunol. 183: 7161-7168.
-
(2009)
J. Immunol.
, vol.183
, pp. 7161-7168
-
-
Yen, H.R.1
Harris, T.J.2
Wada, S.3
Grosso, J.F.4
Getnet, D.5
Goldberg, M.V.6
Liang, K.L.7
Bruno, T.C.8
Pyle, K.J.9
Chan, S.L.10
-
28
-
-
34547734621
-
Phenotypic and functional features of human Th17 cells
-
Annunziato, F., L. Cosmi, V. Santarlasci, L. Maggi, F. Liotta, B. Mazzinghi, E. Parente, L. Filì, S. Ferri, F. Frosali, et al. 2007. Phenotypic and functional features of human Th17 cells. J. Exp. Med. 204: 1849-1861.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1849-1861
-
-
Annunziato, F.1
Cosmi, L.2
Santarlasci, V.3
Maggi, L.4
Liotta, F.5
Mazzinghi, B.6
Parente, E.7
Filì, L.8
Ferri, S.9
Frosali, F.10
-
30
-
-
43549090666
-
+ T cells
-
+ T cells. J. Exp. Med. 205: 1019-1027.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1019-1027
-
-
Tajima, M.1
Wakita, D.2
Noguchi, D.3
Chamoto, K.4
Yue, Z.5
Fugo, K.6
Ishigame, H.7
Iwakura, Y.8
Kitamura, H.9
Nishimura, T.10
-
31
-
-
65449145937
-
Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge
-
Hamada, H., Mde. L. Garcia-Hernandez, J. B. Reome, S. K. Misra, T. M. Strutt, K. K. McKinstry, A. M. Cooper, S. L. Swain, and R. W. Dutton. 2009. Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge. J. Immunol. 182: 3469-3481.
-
(2009)
J. Immunol.
, vol.182
, pp. 3469-3481
-
-
Hamada, H.1
Garcia-Hernandez, M.L.2
Reome, J.B.3
Misra, S.K.4
Strutt, T.M.5
McKinstry, K.K.6
Cooper, A.M.7
Swain, S.L.8
Dutton, R.W.9
-
32
-
-
47949096781
-
Cancer-related inflammation
-
Mantovani, A., P. Allavena, A. Sica, and F. Balkwill. 2008. Cancer-related inflammation. Nature 454: 436-444.
-
(2008)
Nature
, vol.454
, pp. 436-444
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
Balkwill, F.4
-
33
-
-
77950196277
-
H17 cells in tumour immunity and immunotherapy
-
H17 cells in tumour immunity and immunotherapy. Nat. Rev. Immunol. 10: 248-256.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 248-256
-
-
Zou, W.1
Restifo, N.P.2
-
34
-
-
17144398046
-
Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection
-
Guiducci, C., A. P. Vicari, S. Sangaletti, G. Trinchieri, and M. P. Colombo. 2005. Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection. Cancer Res. 65: 3437-3446.
-
(2005)
Cancer Res.
, vol.65
, pp. 3437-3446
-
-
Guiducci, C.1
Vicari, A.P.2
Sangaletti, S.3
Trinchieri, G.4
Colombo, M.P.5
-
35
-
-
47949090079
-
The role of myeloid cells in the promotion of tumour angiogenesis
-
Murdoch, C., M. Muthana, S. B. Coffelt, and C. E. Lewis. 2008. The role of myeloid cells in the promotion of tumour angiogenesis. Nat. Rev. Cancer 8: 618-631.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 618-631
-
-
Murdoch, C.1
Muthana, M.2
Coffelt, S.B.3
Lewis, C.E.4
|