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Volumn 192, Issue 4, 2012, Pages 1235-1248

Insertional mutagenesis by a hybrid piggyBac and Sleeping Beauty transposon in the rat

Author keywords

[No Author keywords available]

Indexed keywords

MONOPHENOL MONOOXYGENASE; PIGGYBAC TRANSPOSASE; SLEEPING BEAUTY TRANSPOSASE; TRANSPOSASE; UNCLASSIFIED DRUG;

EID: 84870664332     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.112.140855     Document Type: Article
Times cited : (23)

References (71)
  • 2
    • 0033529654 scopus 로고    scopus 로고
    • The protein CTCF is required for the enhancer blocking activity of vertebrate insulators
    • Bell, A. C., A. G. West, and G. Felsenfeld, 1999. The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell 98: 387-396
    • (1999) Cell , vol.98 , pp. 387-396
    • Bell, A.C.1    West, A.G.2    Felsenfeld, G.3
  • 3
    • 84865651952 scopus 로고    scopus 로고
    • Culture parameters for stable expansion, genetic modification and germline transmission of rat pluripotent stem cells
    • Blair, K., H. G. Leitch, W. Mansfield, C. E. Dumeau, P. Humphreys et al., 2012. Culture parameters for stable expansion, genetic modification and germline transmission of rat pluripotent stem cells. Biol. Open 1: 58-65
    • (2012) Biol. Open , vol.1 , pp. 58-65
    • Blair, K.1    Leitch, H.G.2    Mansfield, W.3    Dumeau, C.E.4    Humphreys, P.5
  • 4
    • 15944411408 scopus 로고    scopus 로고
    • A Tyrosinase missense mutation causes albinism in the Wistar rat
    • Blaszczyk, W. M., L. Arning, K. P. Hoffmann, and J. T. Epplen, 2005. A Tyrosinase missense mutation causes albinism in the Wistar rat. Pigment Cell Res. 18: 144-145
    • (2005) Pigment Cell Res , vol.18 , pp. 144-145
    • Blaszczyk, W.M.1    Arning, L.2    Hoffmann, K.P.3    Epplen, J.T.4
  • 5
    • 0025914813 scopus 로고
    • RNA-protein interactions within the internal translation initiation region of encephalomyocarditis virus RNA
    • Borovjagin, A. V., M. V. Ezrokhi, V. M. Rostapshov, T. Y. Ugarova, T. F. Bystrova et al., 1991. RNA-protein interactions within the internal translation initiation region of encephalomyocarditis virus RNA. Nucleic Acids Res. 19: 4999-5005
    • (1991) Nucleic Acids Res , vol.19 , pp. 4999-5005
    • Borovjagin, A.V.1    Ezrokhi, M.V.2    Rostapshov, V.M.3    Ugarova, T.Y.4    Bystrova, T.F.5
  • 6
    • 57649181379 scopus 로고    scopus 로고
    • Capture of authentic embryonic stem cells from rat blastocysts
    • Buehr, M., S. Meek, K. Blair, J. Yang, J. Ure et al., 2008. Capture of authentic embryonic stem cells from rat blastocysts. Cell 135: 1287-1298
    • (2008) Cell , vol.135 , pp. 1287-1298
    • Buehr, M.1    Meek, S.2    Blair, K.3    Yang, J.4    Ure, J.5
  • 7
    • 34547638572 scopus 로고    scopus 로고
    • Generation of an inducible and optimized piggyBac transposon system
    • Cadinanos, J., and A. Bradley, 2007. Generation of an inducible and optimized piggyBac transposon system. Nucleic Acids Res. 35: e87
    • (2007) Nucleic Acids Res , vol.35
    • Cadinanos, J.1    Bradley, A.2
  • 9
    • 0035847075 scopus 로고    scopus 로고
    • Transgenic monkeys produced by retroviral gene transfer into mature oocytes
    • Chan, A.W., K. Y. Chong, C. Martinovich, C. Simerly, and G. Schatten, 2001. Transgenic monkeys produced by retroviral gene transfer into mature oocytes. Science 291: 309-312
    • (2001) Science , vol.291 , pp. 309-312
    • Chan, A.W.1    Chong, K.Y.2    Martinovich, C.3    Simerly, C.4    Schatten, G.5
  • 10
    • 77954187597 scopus 로고    scopus 로고
    • PiggyBac transposon-mediated, reversible gene transfer in human embryonic stem cells
    • Chen, Y. T., K. Furushima, P. S. Hou, A. T. Ku, J. M. Deng et al., 2010. PiggyBac transposon-mediated, reversible gene transfer in human embryonic stem cells. Stem Cells Dev. 19: 763-771
    • (2010) Stem Cells Dev , vol.19 , pp. 763-771
    • Chen, Y.T.1    Furushima, K.2    Hou, P.S.3    Ku, A.T.4    Deng, J.M.5
  • 11
    • 0034889110 scopus 로고    scopus 로고
    • The paired homeodomain protein DRG11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord
    • Chen, Z. F., S. Rebelo, F. White, A. B. Malmberg, H. Baba et al., 2001. The paired homeodomain protein DRG11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord. Neuron 31: 59-73
    • (2001) Neuron , vol.31 , pp. 59-73
    • Chen, Z.F.1    Rebelo, S.2    White, F.3    Malmberg, A.B.4    Baba, H.5
  • 12
    • 78651322138 scopus 로고    scopus 로고
    • Targeted integration in rat and mouse embryos with zinc-finger nucleases
    • Cui, X., D. Ji, D. A. Fisher, Y. Wu, D. M. Briner et al., 2011. Targeted integration in rat and mouse embryos with zinc-finger nucleases. Nat. Biotechnol. 29: 64-67
    • (2011) Nat. Biotechnol , vol.29 , pp. 64-67
    • Cui, X.1    Ji, D.2    Fisher, D.A.3    Wu, Y.4    Briner, D.M.5
  • 13
    • 0242636324 scopus 로고    scopus 로고
    • The outs and ins of transposition: From mu to kangaroo
    • Curcio, M. J., and K. M. Derbyshire, 2003. The outs and ins of transposition: from mu to kangaroo. Nat. Rev. Mol. Cell Biol. 4: 865-877
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 865-877
    • Curcio, M.J.1    Derbyshire, K.M.2
  • 14
    • 23744479962 scopus 로고    scopus 로고
    • Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice
    • Ding, S., X. Wu, G. Li, M. Han, and Y. Zhuang, 2005. Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell 122: 473-483
    • (2005) Cell , vol.122 , pp. 473-483
    • Ding, S.1    Wu, X.2    Li, G.3    Han, M.4    Zhuang, Y.5
  • 15
    • 77749233778 scopus 로고    scopus 로고
    • The knockout rat pack
    • Dolgin, E., 2010. The knockout rat pack. Nat. Med. 16: 254-257
    • (2010) Nat. Med , vol.16 , pp. 254-257
    • Dolgin, E.1
  • 16
    • 0034964286 scopus 로고    scopus 로고
    • Transposition and gene disruption in the male germline of the mouse
    • Dupuy, A. J., S. Fritz, and D. A. Largaespada, 2001. Transposition and gene disruption in the male germline of the mouse. Genesis 30: 82-88
    • (2001) Genesis , vol.30 , pp. 82-88
    • Dupuy, A.J.1    Fritz, S.2    Largaespada, D.A.3
  • 18
    • 33751541779 scopus 로고    scopus 로고
    • Advances in transgenic rat production
    • Filipiak, W. E., and T. L. Saunders, 2006. Advances in transgenic rat production. Transgenic Res. 15: 673-686
    • (2006) Transgenic Res , vol.15 , pp. 673-686
    • Filipiak, W.E.1    Saunders, T.L.2
  • 19
    • 0035810931 scopus 로고    scopus 로고
    • Regulated transposition of a fish transposon in the mouse germ line
    • Fischer, S. E., E. Wienholds, and R. H. Plasterk, 2001. Regulated transposition of a fish transposon in the mouse germ line. Proc. Natl. Acad. Sci. USA 98: 6759-6764
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 6759-6764
    • Fischer, S.E.1    Wienholds, E.2    Plasterk, R.H.3
  • 20
    • 33749416026 scopus 로고    scopus 로고
    • Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers
    • Geurts, A. M., L. S. Collier, J. L. Geurts, L. L. Oseth, M. L. Bell et al., 2006. Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers. PLoS Genet. 2: e156
    • (2006) PLoS Genet , vol.2
    • Geurts, A.M.1    Collier, L.S.2    Geurts, J.L.3    Oseth, L.L.4    Bell, M.L.5
  • 21
    • 67749106611 scopus 로고    scopus 로고
    • Knockout rats via embryo microinjection of zinc-finger nucleases
    • Geurts, A. M., G. J. Cost, Y. Freyvert, B. Zeitler, J. C. Miller et al., 2009. Knockout rats via embryo microinjection of zinc-finger nucleases. Science 325: 433
    • (2009) Science , vol.325 , pp. 433
    • Geurts, A.M.1    Cost, G.J.2    Freyvert, Y.3    Zeitler, B.4    Miller, J.C.5
  • 22
    • 77953132759 scopus 로고    scopus 로고
    • Comparative analysis of transposable element vector systems in human cells
    • Grabundzija, I., M. Irgang, L. Mátés, E. Belay, J. Matrai et al., 2010. Comparative analysis of transposable element vector systems in human cells. Mol. Ther. 18: 1200-1209
    • (2010) Mol. Ther , vol.18 , pp. 1200-1209
    • Grabundzija, I.1    Irgang, M.2    Mátés, L.3    Belay, E.4    Matrai, J.5
  • 23
    • 0033160190 scopus 로고    scopus 로고
    • A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection
    • Holcik, M., C. Lefebvre, C. Yeh, T. Chow, and R. G. Korneluk, 1999. A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection. Nat. Cell Biol. 1: 190-192
    • (1999) Nat. Cell Biol , vol.1 , pp. 190-192
    • Holcik, M.1    Lefebvre, C.2    Yeh, C.3    Chow, T.4    Korneluk, R.G.5
  • 24
    • 12644290240 scopus 로고    scopus 로고
    • Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior
    • Homanics, G. E., T. M. DeLorey, L. L. Firestone, J. J. Quinlan, A. Handforth et al., 1997. Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior. Proc. Natl. Acad. Sci. USA 94: 4143-4148
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4143-4148
    • Homanics, G.E.1    DeLorey, T.M.2    Firestone, L.L.3    Quinlan, J.J.4    Handforth, A.5
  • 25
    • 34249080888 scopus 로고    scopus 로고
    • Characterization of the serotonin transporter knockout rat: A selective change in the functioning of the serotonergic system
    • Homberg, J. R., J. D. Olivier, B. M. Smits, J. D. Mul, J. Mudde et al., 2007. Characterization of the serotonin transporter knockout rat: a selective change in the functioning of the serotonergic system. Neuroscience 146: 1662-1676
    • (2007) Neuroscience , vol.146 , pp. 1662-1676
    • Homberg, J.R.1    Olivier, J.D.2    Smits, B.M.3    Mul, J.D.4    Mudde, J.5
  • 26
    • 68549103450 scopus 로고    scopus 로고
    • Complete knockout of the nociceptin/orphanin FQ receptor in the rat does not induce compensatory changes in mu, delta and kappa opioid receptors
    • Homberg, J. R., J. D. Mul, E. de Wit, and E. Cuppen, 2009. Complete knockout of the nociceptin/orphanin FQ receptor in the rat does not induce compensatory changes in mu, delta and kappa opioid receptors. Neuroscience 163: 308-315
    • (2009) Neuroscience , vol.163 , pp. 308-315
    • Homberg, J.R.1    Mul, J.D.2    de Wit, E.3    Cuppen, E.4
  • 27
    • 0035979255 scopus 로고    scopus 로고
    • Efficient chromosomal transposition of a Tc1/marinerlike transposon Sleeping Beauty in mice
    • Horie, K., A. Kuroiwa, M. Ikawa, M. Okabe, G. Kondoh et al., 2001. Efficient chromosomal transposition of a Tc1/marinerlike transposon Sleeping Beauty in mice. Proc. Natl. Acad. Sci. USA 98: 9191-9196
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9191-9196
    • Horie, K.1    Kuroiwa, A.2    Ikawa, M.3    Okabe, M.4    Kondoh, G.5
  • 28
    • 10744231615 scopus 로고    scopus 로고
    • Characterization of Sleeping Beauty transposition and its application to genetic screening in mice
    • Horie, K., K. Yusa, K. Yae, J. Odajima, S. E. Fischer et al., 2003. Characterization of Sleeping Beauty transposition and its application to genetic screening in mice. Mol. Cell. Biol. 23: 9189-9207
    • (2003) Mol. Cell. Biol , vol.23 , pp. 9189-9207
    • Horie, K.1    Yusa, K.2    Yae, K.3    Odajima, J.4    Fischer, S.E.5
  • 29
    • 0030662074 scopus 로고    scopus 로고
    • Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells
    • Ivics, Z., P. B. Hackett, R. H. Plasterk, and Z. Izsvak, 1997. Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells. Cell 91: 501-510
    • (1997) Cell , vol.91 , pp. 501-510
    • Ivics, Z.1    Hackett, P.B.2    Plasterk, R.H.3    Izsvak, Z.4
  • 30
    • 10744227295 scopus 로고    scopus 로고
    • Healing the wounds inflicted by sleeping beauty transposition by double-strand break repair in mammalian somatic cells
    • Izsvák, Z., E. E. Stüwe, D. Fiedler, A. Katzer, P. A. Jeggo et al., 2004. Healing the wounds inflicted by sleeping beauty transposition by double-strand break repair in mammalian somatic cells. Mol. Cell 13: 279-290
    • (2004) Mol. Cell , vol.13 , pp. 279-290
    • Izsvák, Z.1    Stüwe, E.E.2    Fiedler, D.3    Katzer, A.4    Jeggo, P.A.5
  • 31
    • 77953025048 scopus 로고    scopus 로고
    • Generating knockout rats by transposon mutagenesis in spermatogonial stem cells
    • Izsvák, Z., J. Fröhlich, I. Grabundzija, J. R. Shirley, H. M. Powell et al., 2010. Generating knockout rats by transposon mutagenesis in spermatogonial stem cells. Nat. Methods 7: 443-445
    • (2010) Nat. Methods , vol.7 , pp. 443-445
    • Izsvák, Z.1    Fröhlich, J.2    Grabundzija, I.3    Shirley, J.R.4    Powell, H.M.5
  • 33
    • 0028210480 scopus 로고
    • Position-effect variegation and the new biology of heterochromatin
    • Karpen, G. H., 1994. Position-effect variegation and the new biology of heterochromatin. Curr. Opin. Genet. Dev. 4: 281-291
    • (1994) Curr. Opin. Genet. Dev , vol.4 , pp. 281-291
    • Karpen, G.H.1
  • 34
    • 77956294479 scopus 로고    scopus 로고
    • Generation of genetically modified rats from embryonic stem cells
    • Kawamata, M., and T. Ochiya, 2010. Generation of genetically modified rats from embryonic stem cells. Proc. Natl. Acad. Sci. USA 107: 14223-14228
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 14223-14228
    • Kawamata, M.1    Ochiya, T.2
  • 36
    • 57649245579 scopus 로고    scopus 로고
    • Germline competent embryonic stem cells derived from rat blastocysts
    • Li, P., C. Tong, R. Mehrian-Shai, L. Jia, N. Wu et al., 2008. Germline competent embryonic stem cells derived from rat blastocysts. Cell 135: 1299-1310
    • (2008) Cell , vol.135 , pp. 1299-1310
    • Li, P.1    Tong, C.2    Mehrian-Shai, R.3    Jia, L.4    Wu, N.5
  • 37
    • 0034790136 scopus 로고    scopus 로고
    • The minimum internal and external sequence requirements for transposition of the eukaryotic transformation vector piggyBac
    • Li, X., N. Lobo, C. A. Bauser, and M. J. Fraser Jr., 2001. The minimum internal and external sequence requirements for transposition of the eukaryotic transformation vector piggyBac. Mol. Genet. Genomics 266: 190-198
    • (2001) Mol. Genet. Genomics , vol.266 , pp. 190-198
    • Li, X.1    Lobo, N.2    Bauser, C.A.3    Fraser Jr., M.J.4
  • 38
    • 70349176337 scopus 로고    scopus 로고
    • Chromosomal mobilization and reintegration of Sleeping Beauty and PiggyBac transposons
    • Liang, Q., J. Kong, J. Stalker, and A. Bradley, 2009. Chromosomal mobilization and reintegration of Sleeping Beauty and PiggyBac transposons. Genesis 47: 404-408
    • (2009) Genesis , vol.47 , pp. 404-408
    • Liang, Q.1    Kong, J.2    Stalker, J.3    Bradley, A.4
  • 39
    • 0036468677 scopus 로고    scopus 로고
    • Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
    • Lois, C., E. J. Hong, S. Pease, E. J. Brown, and D. Baltimore, 2002. Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science 295: 868-872
    • (2002) Science , vol.295 , pp. 868-872
    • Lois, C.1    Hong, E.J.2    Pease, S.3    Brown, E.J.4    Baltimore, D.5
  • 40
    • 34547102476 scopus 로고    scopus 로고
    • Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system
    • Lu, B., A. M. Geurts, C. Poirier, D. C. Petit, W. Harrison et al., 2007. Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system. Mamm. Genome 18: 338-346
    • (2007) Mamm. Genome , vol.18 , pp. 338-346
    • Lu, B.1    Geurts, A.M.2    Poirier, C.3    Petit, D.C.4    Harrison, W.5
  • 42
    • 77749273530 scopus 로고    scopus 로고
    • Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases
    • Mashimo, T., A. Takizawa, B. Voigt, K. Yoshimi, H. Hiai et al., 2010. Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases. PLoS ONE 5: e8870
    • (2010) PLoS ONE , vol.5
    • Mashimo, T.1    Takizawa, A.2    Voigt, B.3    Yoshimi, K.4    Hiai, H.5
  • 43
    • 0031800261 scopus 로고    scopus 로고
    • Gene trap integrations expressed in the developing heart: Insertion site affects splicing of the PT1-ATG vector
    • McClive, P., G. Pall, K. Newton, M. Lee, J. Mullins et al., 1998. Gene trap integrations expressed in the developing heart: insertion site affects splicing of the PT1-ATG vector. Dev. Dyn. 212: 267-276
    • (1998) Dev. Dyn , vol.212 , pp. 267-276
    • McClive, P.1    Pall, G.2    Newton, K.3    Lee, M.4    Mullins, J.5
  • 44
    • 54949102311 scopus 로고    scopus 로고
    • Regulation of spermatogonial stem cell self-renewal in mammals
    • Oatley, J. M., and R. L. Brinster, 2008. Regulation of spermatogonial stem cell self-renewal in mammals. Annu. Rev. Cell Dev. Biol. 24: 263-286
    • (2008) Annu. Rev. Cell Dev. Biol , vol.24 , pp. 263-286
    • Oatley, J.M.1    Brinster, R.L.2
  • 45
    • 40949084721 scopus 로고    scopus 로고
    • A study in male and female 5-HT transporter knockout rats: An animal model for anxiety and depression disorders
    • Olivier, J. D., M. G. Van Der Hart, R. P. Van Swelm, P. J. Dederen, J. R. Homberg et al., 2008. A study in male and female 5-HT transporter knockout rats: an animal model for anxiety and depression disorders. Neuroscience 152: 573-584
    • (2008) Neuroscience , vol.152 , pp. 573-584
    • Olivier, J.D.1    Van Der Hart, M.G.2    van Swelm, R.P.3    Dederen, P.J.4    Homberg, J.R.5
  • 46
    • 84941046878 scopus 로고    scopus 로고
    • Factors affecting transgenic animal production
    • Ed. 2, edited by C. A. Pinkert. Elsevier Science, New York
    • Overbeek, P. A., 2002. Factors affecting transgenic animal production, pp. 72-111 in Transgenic Animal Technology: A Laboratory Handbook, Ed. 2, edited by C. A. Pinkert. Elsevier Science, New York
    • (2002) Transgenic Animal Technology: A Laboratory Handbook , pp. 72-111
    • Overbeek, P.A.1
  • 48
    • 0032530174 scopus 로고    scopus 로고
    • Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators
    • Pikaart, M. J., F. Recillas-Targa, and G. Felsenfeld, 1998. Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators. Genes Dev. 12: 2852-2862
    • (1998) Genes Dev , vol.12 , pp. 2852-2862
    • Pikaart, M.J.1    Recillas-Targa, F.2    Felsenfeld, G.3
  • 49
    • 1842684068 scopus 로고    scopus 로고
    • Genome sequence of the Brown Norway rat yields insights into mammalian evolution
    • Rat Genome Sequencing Consortium
    • Rat Genome Sequencing Consortium, 2004. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature 428: 493-521
    • (2004) Nature , vol.428 , pp. 493-521
  • 51
    • 79953176250 scopus 로고    scopus 로고
    • Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor
    • Ruf, S., O. Symmons, V. V. Uslu, D. Dolle, C. Hot et al., 2011. Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor. Nat. Genet. 43: 379-386
    • (2011) Nat. Genet , vol.43 , pp. 379-386
    • Ruf, S.1    Symmons, O.2    Uslu, V.V.3    Dolle, D.4    Hot, C.5
  • 52
    • 0002437748 scopus 로고
    • Molecular Cloning: A Laboratory Manual
    • edited by J. Sambrook, E. F. Fritsch, and T. Maniatis. Press, Cold Spring Harbor, NY
    • Sambrook, J., E. F. Fritsch, and T. Maniatis, 1989. Molecular Cloning: A Laboratory Manual, edited by J. Sambrook, E. F. Fritsch, and T. Maniatis. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • (1989) Cold Spring Harbor Laboratory
    • Sambrook, J.1    Fritsch, E.F.2    Maniatis, T.3
  • 53
    • 66449106662 scopus 로고    scopus 로고
    • Generation of transgenic non-human primates with germline transmission
    • Sasaki, E., H. Suemizu, A. Shimada, K. Hanazawa, R. Oiwa et al., 2009. Generation of transgenic non-human primates with germline transmission. Nature 459: 523-527
    • (2009) Nature , vol.459 , pp. 523-527
    • Sasaki, E.1    Suemizu, H.2    Shimada, A.3    Hanazawa, K.4    Oiwa, R.5    et al6
  • 54
    • 25444525667 scopus 로고    scopus 로고
    • Identification of a rat model for usher syndrome type 1B by N-ethyl-N-nitrosourea mutagenesis-driven forward genetics
    • Smits, B. M., T. A. Peters, J. D. Mul, H. J. Croes, J. A. Fransen et al., 2005. Identification of a rat model for usher syndrome type 1B by N-ethyl-N-nitrosourea mutagenesis-driven forward genetics. Genetics 170: 1887-1896
    • (2005) Genetics , vol.170 , pp. 1887-1896
    • Smits, B.M.1    Peters, T.A.2    Mul, J.D.3    Croes, H.J.4    Fransen, J.A.5
  • 55
    • 33644601589 scopus 로고    scopus 로고
    • Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis
    • Smits, B. M., J. B. Mudde, J. van de Belt, M. Verheul, J. Olivier et al., 2006. Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis. Pharmacogenet. Genomics 16: 159-169
    • (2006) Pharmacogenet. Genomics , vol.16 , pp. 159-169
    • Smits, B.M.1    Mudde, J.B.2    van de Belt, J.3    Verheul, M.4    Olivier, J.5
  • 56
    • 0035873786 scopus 로고    scopus 로고
    • Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice
    • Sur, C., K. A. Wafford, D. S. Reynolds, K. L. Hadingham, F. Bromidge et al., 2001. Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice. J. Neurosci. 21: 3409-3418
    • (2001) J. Neurosci , vol.21 , pp. 3409-3418
    • Sur, C.1    Wafford, K.A.2    Reynolds, D.S.3    Hadingham, K.L.4    Bromidge, F.5
  • 57
    • 79961196358 scopus 로고    scopus 로고
    • Knockout rats generated by embryo microinjection of TALENs
    • Tesson, L, C. Usal, S. Ménoret, E. Leung, B. J. Niles et al., 2011. Knockout rats generated by embryo microinjection of TALENs. Nat. Biotechnol. 29: 695-696
    • (2011) Nat. Biotechnol , vol.29 , pp. 695-696
    • Tesson, L.C.1    Usal, S.2    Ménoret, E.3    Leung, B.J.4    Niles5
  • 58
    • 77956524118 scopus 로고    scopus 로고
    • Production of p53 gene knockout rats by homologous recombination in embryonic stem cells
    • Tong, C., P. Li, N. L. Wu, Y. Yan, and Q. L. Ying, 2010. Production of p53 gene knockout rats by homologous recombination in embryonic stem cells. Nature 467: 211-213
    • (2010) Nature , vol.467 , pp. 211-213
    • Tong, C.1    Li, P.2    Wu, N.L.3    Yan, Y.4    Ying, Q.L.5
  • 59
    • 84863100905 scopus 로고    scopus 로고
    • Rapid and cost-effective gene targeting in rat embryonic stem cells by TALENs
    • Tong, C., G. Huang, C. Ashton, H. Wu, H. Yan et al., 2012. Rapid and cost-effective gene targeting in rat embryonic stem cells by TALENs. J. Genet. Genomics 39: 275-280
    • (2012) J. Genet. Genomics , vol.39 , pp. 275-280
    • Tong, C.1    Huang, G.2    Ashton, C.3    Wu, H.4    Yan, H.5
  • 60
    • 77952369001 scopus 로고    scopus 로고
    • Helper-independent piggyBac plasmids for gene delivery approaches: Strategies for avoiding potential genotoxic effects
    • Urschitz, J., M. Kawasumi, J. Owens, K. Morozumi, H. Yamashiro et al., 2010. Helper-independent piggyBac plasmids for gene delivery approaches: strategies for avoiding potential genotoxic effects. Proc. Natl. Acad. Sci. USA 107: 8117-8122
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 8117-8122
    • Urschitz, J.1    Kawasumi, M.2    Owens, J.3    Morozumi, K.4    Yamashiro, H.5
  • 61
    • 54049093244 scopus 로고    scopus 로고
    • Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals
    • van Boxtel, R., P. W. Toonen, M. Verheul, H. S. van Roekel, I. J. Nijman et al., 2008. Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals. BMC Genomics 9: 460
    • (2008) BMC Genomics , vol.9 , pp. 460
    • van Boxtel, R.1    Toonen, P.W.2    Verheul, M.3    van Roekel, H.S.4    Nijman, I.J.5
  • 62
    • 77449094451 scopus 로고    scopus 로고
    • ENU mutagenesis to generate genetically modified rat models
    • van Boxtel, R., M. N. Gould, E. Cuppen, and B. M. Smits, 2010. ENU mutagenesis to generate genetically modified rat models. Methods Mol. Biol. 597: 151-167
    • (2010) Methods Mol. Biol , vol.597 , pp. 151-167
    • van Boxtel, R.1    Gould, M.N.2    Cuppen, E.3    Smits, B.M.4
  • 63
    • 0018688932 scopus 로고
    • Comparison of total sequence of a cloned rabbit betaglobin gene and its flanking regions with a homologous mouse sequence
    • van Ooyen, A., J. van den Berg, N. Mantei, and C. Weissmann, 1979. Comparison of total sequence of a cloned rabbit betaglobin gene and its flanking regions with a homologous mouse sequence. Science 206: 337-344
    • (1979) Science , vol.206 , pp. 337-344
    • van Ooyen, A.1    van den Berg, J.2    Mantei, N.3    Weissmann, C.4
  • 64
    • 0031748836 scopus 로고    scopus 로고
    • Compensation for a gene trap mutation in the murine microtubule-associated protein 4 locus by alternative polyadenylation and alternative splicing
    • Voss, A. K., T. Thomas, and P. Gruss, 1998. Compensation for a gene trap mutation in the murine microtubule-associated protein 4 locus by alternative polyadenylation and alternative splicing. Dev. Dyn. 212: 258-266
    • (1998) Dev. Dyn , vol.212 , pp. 258-266
    • Voss, A.K.1    Thomas, T.2    Gruss, P.3
  • 65
    • 48249130858 scopus 로고    scopus 로고
    • Chromosomal transposition of PiggyBac in mouse embryonic stem cells
    • Wang, W., C. Lin, D. Lu, Z. Ning, T. Cox et al., 2008. Chromosomal transposition of PiggyBac in mouse embryonic stem cells. Proc. Natl. Acad. Sci. USA 105: 9290-9295
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 9290-9295
    • Wang, W.1    Lin, C.2    Lu, D.3    Ning, Z.4    Cox, T.5
  • 66
    • 64749083939 scopus 로고    scopus 로고
    • PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
    • Woltjen, K., I. P. Michael, P. Mohseni, R. Desai, M. Mileikovsky et al., 2009. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458: 766-770
    • (2009) Nature , vol.458 , pp. 766-770
    • Woltjen, K.1    Michael, I.P.2    Mohseni, P.3    Desai, R.4    Mileikovsky, M.5
  • 67
    • 33750060436 scopus 로고    scopus 로고
    • PiggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cells
    • Wu, S. C., Y. J. Meir, C. J. Coates, A. M. Handler, P. Pelczar et al., 2006. piggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cells. Proc. Natl. Acad. Sci. USA 103: 15008-15013
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 15008-15013
    • Wu, S.C.1    Meir, Y.J.2    Coates, C.J.3    Handler, A.M.4    Pelczar, P.5
  • 68
    • 4744374701 scopus 로고    scopus 로고
    • Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: Critical residues for DNA binding and hyperactivity in mammalian cells
    • Yant, S. R., J. Park, Y. Huang, J. G. Mikkelsen, and M. A. Kay, 2004. Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cells. Mol. Cell. Biol. 24: 9239-9247
    • (2004) Mol. Cell. Biol , vol.24 , pp. 9239-9247
    • Yant, S.R.1    Park, J.2    Huang, Y.3    Mikkelsen, J.G.4    Kay, M.A.5
  • 69
    • 0029865895 scopus 로고    scopus 로고
    • Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells
    • Yeom, Y. I., G. Fuhrmann, C. E. Ovitt, A. Brehm, K. Ohbo et al., 1996. Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells. Development 122: 881-
    • (1996) Development , vol.122
    • Yeom, Y.I.1    Fuhrmann, G.2    Ovitt, C.E.3    Brehm, A.4    Ohbo, K.5
  • 70
    • 0025679209 scopus 로고
    • Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice
    • Yokoyama, T., D. W. Silversides, K. G. Waymire, B. S. Kwon, T. Takeuchi et al., 1990. Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice. Nucleic Acids Res. 18: 7293-7298
    • (1990) Nucleic Acids Res , vol.18 , pp. 7293-7298
    • Yokoyama, T.1    Silversides, D.W.2    Waymire, K.G.3    Kwon, B.S.4    Takeuchi, T.5
  • 71
    • 0037685273 scopus 로고    scopus 로고
    • Production of knockout rats using ENU mutagenesis and a yeast-based screening assay
    • Zan, Y., J. D. Haag, K. S. Chen, L. A. Shepel, D. Wigington et al., 2003. Production of knockout rats using ENU mutagenesis and a yeast-based screening assay. Nat. Biotechnol. 21: 645-651
    • (2003) Nat. Biotechnol , vol.21 , pp. 645-651
    • Zan, Y.1    Haag, J.D.2    Chen, K.S.3    Shepel, L.A.4    Wigington, D.5


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