Structural mechanisms of allostery and autoinhibition in JNK family kinases

Structure

Volumn 20, Issue 12, 2012, Pages 2174-2184

  Laughlin, John D ^a   Nwachukwu, Jerome C ^a   Figuera Losada, Mariana ^a   Cherry, Lisa ^a   Nettles, Kendall W ^a   Lograsso, Philip V ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 12; STRESS ACTIVATED PROTEIN KINASE;

ALLOSTERISM; ARTICLE; CALORIMETRY; ENZYME ACTIVATION; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME STRUCTURE; FLUORESCENCE RESONANCE ENERGY TRANSFER; MOLECULAR LIBRARY; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

ACTIVATING TRANSCRIPTION FACTOR 2; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALLOSTERIC REGULATION; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 10; MITOGEN-ACTIVATED PROTEIN KINASE 8; MODELS, MOLECULAR; OLIGOPEPTIDES; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PROTEIN STRUCTURE, SECONDARY; SUBSTRATE SPECIFICITY;

EID: 84870535838     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2012.09.021     Document Type: Article

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