메뉴 건너뛰기




Volumn 287, Issue 16, 2012, Pages 13291-13302

Enzyme kinetics and interaction studies for human JNK1β1 and substrates Activating Transcription Factor 2 (ATF2) and c-Jun N-terminal kinase (c-Jun)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; BIOCHEMICAL CHARACTERIZATION; C-JUN N-TERMINAL KINASE; ENZYMATIC ACTIVITIES; GLUCOSE INTOLERANCE; INSULIN RESISTANCE; INTERACTION KINETICS; JNK-INTERACTING PROTEIN-1; KINETIC MECHANISM; REGULATORY PROTEIN; SEQUENTIAL MECHANISM; STRESS SIGNALS; TERNARY COMPLEX;

EID: 84859744067     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.323766     Document Type: Article
Times cited : (20)

References (51)
  • 2
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • DOI 10.1016/0092-8674(94)90380-8
    • Dérijard, B., Hibi, M., Wu, I. H., Barrett, T., Su, B., Deng, T., Karin, M., and Davis, R. J. (1994) JNK1, a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76, 1025-1037 (Pubitemid 24106383)
    • (1994) Cell , vol.76 , Issue.6 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.-H.3    Barrett, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.J.8
  • 4
    • 0030198344 scopus 로고    scopus 로고
    • Protein kinase cascades activated by stress and inflammatory cytokines
    • Kyriakis, J. M., and Avruch, J. (1996) Protein kinase cascades activated by stress and inflammatory cytokines. Bioessays 18, 567-577 (Pubitemid 26311096)
    • (1996) BioEssays , vol.18 , Issue.7 , pp. 567-577
    • Kyriakis, J.M.1    Avruch, J.2
  • 5
    • 0028130213 scopus 로고
    • Tumor necrosis factor α stimulates AP-1 activity through prolonged activation of the c-Jun kinase
    • Westwick, J. K., Weitzel, C., Minden, A., Karin, M., and Brenner, D. A. (1994) Tumor necrosis factor α stimulates AP-1 activity through prolonged activation of the c-Jun kinase. J. Biol. Chem. 269, 26396-26401 (Pubitemid 24328461)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.42 , pp. 26396-26401
    • Westwick, J.K.1    Weitzel, C.2    Minden, A.3    Karin, M.4    Brenner, D.A.5
  • 6
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis, R. J. (2000) Signal transduction by the JNK group of MAP kinases. Cell 103, 239-252
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 7
    • 0028061674 scopus 로고
    • Signal transduction by tumor necrosis factor mediated by JNK protein kinases
    • Sluss, H. K., Barrett, T., Dérijard, B., and Davis, R. J. (1994) Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Mol. Cell Biol. 14, 8376-8384 (Pubitemid 24373586)
    • (1994) Molecular and Cellular Biology , vol.14 , Issue.12 , pp. 8376-8384
    • Sluss, H.K.1    Barrett, T.2    Derijard, B.3    Davis, R.J.4
  • 8
    • 0028609209 scopus 로고
    • JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation
    • Kallunki, T., Su, B., Tsigelny, I., Sluss, H. K., Dérijard, B., Moore, G., Davis, R., and Karin, M. (1994) JNK2 contains a specificity- determining region responsible for efficient c-Jun binding and phosphorylation. Genes Dev. 8, 2996-3007
    • (1994) Genes Dev. , vol.8 , pp. 2996-3007
    • Kallunki, T.1    Su, B.2    Tsigelny, I.3    Sluss, H.K.4    Dérijard, B.5    Moore, G.6    Davis, R.7    Karin, M.8
  • 9
    • 0028984151 scopus 로고
    • p493F12 kinase. A novel MAP kinase expressed in a subset of neurons in the human nervous system
    • Mohit, A. A., Martin, J. H., and Miller, C. A. (1995) p493F12 kinase. A novel MAP kinase expressed in a subset of neurons in the human nervous system. Neuron 14, 67-78
    • (1995) Neuron , vol.14 , pp. 67-78
    • Mohit, A.A.1    Martin, J.H.2    Miller, C.A.3
  • 10
    • 0029885419 scopus 로고    scopus 로고
    • Selective interaction of JNK protein kinase isoforms with transcription factors
    • Gupta, S., Barrett, T., Whitmarsh, A. J., Cavanagh, J., Sluss, H. K., Dérijard, B., and Davis, R. J. (1996) Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J. 15, 2760-2770 (Pubitemid 26176253)
    • (1996) EMBO Journal , vol.15 , Issue.11 , pp. 2760-2770
    • Gupta, S.1    Barrett, T.2    Whitmarsh, A.J.3    Cavanagh, J.4    Sluss, H.K.5    Derijard, B.6    Davis, R.J.7
  • 14
    • 0346037264 scopus 로고    scopus 로고
    • JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins
    • DOI 10.1016/S1534-5807(03)00094-7, PII S1534580703000947
    • Chang, L., Jones, Y., Ellisman, M. H., Goldstein, L. S., and Karin, M. (2003) JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins. Dev. Cell 4, 521-533 (Pubitemid 36437559)
    • (2003) Developmental Cell , vol.4 , Issue.4 , pp. 521-533
    • Chang, L.1    Jones, Y.2    Ellisman, M.H.3    Goldstein, L.S.B.4    Karin, M.5
  • 15
    • 0032509479 scopus 로고    scopus 로고
    • Defective T cell differentiation in the absence of Jnk1
    • DOI 10.1126/science.282.5396.2092
    • Dong, C., Yang, D. D., Wysk, M., Whitmarsh, A. J., Davis, R. J., and Flavell, R. A. (1998) Defective T cell differentiation in the absence of Jnk1. Science 282, 2092-2095 (Pubitemid 29001267)
    • (1998) Science , vol.282 , Issue.5396 , pp. 2092-2095
    • Dong, C.1    Yang, D.D.2    Wysk, M.3    Whitmarsh, A.J.4    Davis, R.J.5    Flavell, R.A.6
  • 16
    • 10044247350 scopus 로고    scopus 로고
    • c-Jun N-terminal protein kinase 1 (JNK1), but not JNK2, is essential for tumor necrosis factor alpha-induced c-Jun kinase activation and apoptosis
    • DOI 10.1128/MCB.24.24.10844-10856.2004
    • Liu, J., Minemoto, Y., and Lin, A. (2004) c-Jun N-terminal protein kinase 1 (JNK1), but not JNK2, is essential for tumor necrosis factor α-induced c-Jun kinase activation and apoptosis. Mol. Cell. Biol. 24, 10844-10856 (Pubitemid 39603140)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.24 , pp. 10844-10856
    • Liu, J.1    Minemoto, Y.2    Lin, A.3
  • 17
    • 4444341881 scopus 로고    scopus 로고
    • Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation
    • DOI 10.1016/j.molcel.2004.08.028, PII S1097276504005143
    • Sabapathy, K., Hochedlinger, K., Nam, S. Y., Bauer, A., Karin, M., and Wagner, E. F. (2004) Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation. Mol. Cell 15, 713-725 (Pubitemid 39194902)
    • (2004) Molecular Cell , vol.15 , Issue.5 , pp. 713-725
    • Sabapathy, K.1    Hochedlinger, K.2    Nam, S.Y.3    Bauer, A.4    Karin, M.5    Wagner, E.F.6
  • 19
    • 0030780804 scopus 로고    scopus 로고
    • Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
    • DOI 10.1038/39899
    • Yang, D. D., Kuan, C. Y., Whitmarsh, A. J., Rincón, M., Zheng, T. S., Davis, R. J., Rakic, P., and Flavell, R. A. (1997) Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature 389, 865-870 (Pubitemid 27462982)
    • (1997) Nature , vol.389 , Issue.6653 , pp. 865-870
    • Yang, D.D.1    Kuan, C.-Y.2    Whitmarsh, A.J.3    Rincon, M.4    Zheng, T.S.5    Davis, R.J.6    Rakic, P.7    Flavell, R.A.8
  • 20
    • 0034724978 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase (JNK) and JNK interacting protein response in rat brain after transient middle cerebral artery occlusion
    • DOI 10.1016/S0304-3940(00)01024-7, PII S0304394000010247
    • Hayashi, T., Sakai, K., Sasaki, C., Zhang, W. R., Warita, H., and Abe, K. (2000) c-Jun N-terminal kinase (JNK) and JNK interacting protein response in rat brain after transient middle cerebral artery occlusion. Neurosci. Lett. 284, 195-199 (Pubitemid 30204546)
    • (2000) Neuroscience Letters , vol.284 , Issue.3 , pp. 195-199
    • Hayashi, T.1    Sakai, K.-I.2    Sasaki, C.3    Zhang, W.R.4    Warita, H.5    Abe, K.6
  • 21
    • 0034918203 scopus 로고    scopus 로고
    • JNK3 contributes to c-Jun activation and apoptosis but not oxidative stress in nerve growth factor-deprived sympathetic neurons
    • DOI 10.1046/j.1471-4159.2001.00400.x
    • Bruckner, S. R., Tammariello, S. P., Kuan, C. Y., Flavell, R. A., Rakic, P., and Estus, S. (2001) JNK3 contributes to c-Jun activation and apoptosis but not oxidative stress in nerve growth factor-deprived sympathetic neurons, J. Neurochem. 78, 298-303 (Pubitemid 32664411)
    • (2001) Journal of Neurochemistry , vol.78 , Issue.2 , pp. 298-303
    • Bruckner, S.R.1    Tammariello, S.P.2    Kuan, C.-Y.3    Flavell, R.A.4    Rakic, P.5    Estus, S.6
  • 22
    • 34347259974 scopus 로고    scopus 로고
    • Activation of c-Jun N-terminal protein kinase is a common mechanism underlying paraquat- and rotenone-induced dopaminergic cell apoptosis
    • DOI 10.1093/toxsci/kfm029
    • Klintworth, H., Newhouse, K., Li, T., Choi, W. S., Faigle, R., and Xia, Z. (2007) Activation of c-Jun N-terminal protein kinase is a common mechanism underlying paraquat- and rotenone-induced dopaminergic cell apoptosis. Toxicol. Sci. 97, 149-162 (Pubitemid 47072164)
    • (2007) Toxicological Sciences , vol.97 , Issue.1 , pp. 149-162
    • Klintworth, H.1    Newhouse, K.2    Li, T.3    Choi, W.-S.4    Faigle, R.5    Xia, Z.6
  • 23
    • 0035478618 scopus 로고    scopus 로고
    • β-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of fas ligand
    • Morishima, Y., Gotoh, Y., Zieg, J., Barrett, T., Takano, H., Flavell, R., Davis, R. J., Shirasaki, Y., and Greenberg, M. E. (2001) β-Amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand. J. Neurosci. 21, 7551-7560 (Pubitemid 32904954)
    • (2001) Journal of Neuroscience , vol.21 , Issue.19 , pp. 7551-7560
    • Morishima, Y.1    Gotoh, Y.2    Zieg, J.3    Barrett, T.4    Takano, H.5    Flavell, R.6    Davis, R.J.7    Shirasaki, Y.8    Greenberg, M.E.9
  • 24
    • 0035339885 scopus 로고    scopus 로고
    • 1
    • Dreskin, S. C., Thomas, G. W., Dale, S. N., and Heasley, L. E. (2001) Isoforms of Jun kinase are differentially expressed and activated in human monocyte/macrophage (THP-1) cells. J. Immunol. 166, 5646-5653 (Pubitemid 32374188)
    • (2001) Journal of Immunology , vol.166 , Issue.9 , pp. 5646-5653
    • Dreskin, S.C.1    Thomas, G.W.2    Dale, S.N.3    Heasley, L.E.4
  • 27
    • 50349089225 scopus 로고    scopus 로고
    • Mechanistic characterization for c-Jun N-terminal kinase 1α1
    • Ember, B., and LoGrasso, P. (2008) Mechanistic characterization for c-Jun N-terminal kinase 1α1. Arch. Biochem. Biophys. 477, 324-329
    • (2008) Arch. Biochem. Biophys. , vol.477 , pp. 324-329
    • Ember, B.1    LoGrasso, P.2
  • 28
    • 40549109546 scopus 로고    scopus 로고
    • Kinetic mechanism and inhibitor characterization for c-jun-N-terminal kinase 3α1
    • DOI 10.1021/bi701852z
    • Ember, B., Kamenecka, T., and LoGrasso, P. (2008) Kinetic mechanism and inhibitor characterization for c-Jun N-terminal kinase 3α1. Biochemistry 47, 3076-3084 (Pubitemid 351364901)
    • (2008) Biochemistry , vol.47 , Issue.10 , pp. 3076-3084
    • Ember, B.1    Kamenecka, T.2    LoGrasso, P.3
  • 29
    • 34247517344 scopus 로고    scopus 로고
    • Kinetic characterization of human JNK2α2 reaction mechanism using substrate competitive inhibitors
    • DOI 10.1021/bi602423e
    • Niu, L., Chang, K. C., Wilson, S., Tran, P., Zuo, F., and Swinney, D. C. (2007) Kinetic characterization of human JNK2α2 reaction mechanism using substrate competitive inhibitors. Biochemistry 46, 4775-4784 (Pubitemid 46651200)
    • (2007) Biochemistry , vol.46 , Issue.16 , pp. 4775-4784
    • Niu, L.1    Chang, K.-C.2    Wilson, S.3    Tran, P.4    Zuo, F.5    Swinney, D.C.6
  • 30
    • 0034696630 scopus 로고    scopus 로고
    • Activation of JNK3α1 requires both MKK4 and MKK7. Kinetic characterization of in vitro phosphorylated JNK3α1
    • Lisnock, J., Griffin, P., Calaycay, J., Frantz, B., Parsons, J., O'Keefe, S. J., and LoGrasso, P. (2000) Activation of JNK3α1 requires both MKK4 and MKK7. Kinetic characterization of in vitro phosphorylated JNK3α1. Biochemistry 39, 3141-3148
    • (2000) Biochemistry , vol.39 , pp. 3141-3148
    • Lisnock, J.1    Griffin, P.2    Calaycay, J.3    Frantz, B.4    Parsons, J.5    O'Keefe, S.J.6    LoGrasso, P.7
  • 31
    • 0011756062 scopus 로고    scopus 로고
    • 5 Ed., Erithacus Software Limited, Surrey, United Kingdom
    • Leatherbarrow, R. J. (2001) GraFit, 5 Ed., Erithacus Software Limited, Surrey, United Kingdom
    • (2001) GraFit
    • Leatherbarrow, R.J.1
  • 32
    • 0037192843 scopus 로고    scopus 로고
    • Identification of the critical features of a small peptide inhibitor of JNK activity
    • DOI 10.1074/jbc.M107565200
    • Barr, R. K., Kendrick, T. S., and Bogoyevitch, M. A. (2002) Identification of the critical features of a small peptide inhibitor of JNK activity. J. Biol. Chem. 277, 10987-10997 (Pubitemid 34952855)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.13 , pp. 10987-10997
    • Barr, R.K.1    Kendrick, T.S.2    Bogoyevitch, M.A.3
  • 33
    • 0003518480 scopus 로고
    • Wiley-Interscience, New York
    • Segel, I. H. (1975) Enzyme Kinetics, Wiley-Interscience, New York
    • (1975) Enzyme Kinetics
    • Segel, I.H.1
  • 34
    • 34250159508 scopus 로고    scopus 로고
    • Necrotic death of neurons following an excitotoxic insult is prevented by a peptide inhibitor of c-jun N-terminal kinase
    • DOI 10.1111/j.1471-4159.2007.04618.x
    • Arthur, P. G., Matich, G. P., Pang, W. W., Yu, D. Y., and Bogoyevitch, M. A. (2007) Necrotic death of neurons following an excitotoxic insult is prevented by a peptide inhibitor of c-Jun N-terminal kinase. J. Neurochem. 102, 65-76 (Pubitemid 46906274)
    • (2007) Journal of Neurochemistry , vol.102 , Issue.1 , pp. 65-76
    • Arthur, P.G.1    Matich, G.P.2    Pang, W.W.3    Yu, D.-Y.4    Bogoyevitch, M.A.5
  • 41
    • 0042915882 scopus 로고    scopus 로고
    • The structure of JNK3 in complex with small molecule inhibitors: Structural basis for potency and selectivity
    • DOI 10.1016/S1074-5521(03)00159-5
    • Scapin, G., Patel, S. B., Lisnock, J., Becker, J. W., and LoGrasso, P. V. (2003) The structure of JNK3 in complex with small molecule inhibitors. Structural basis for potency and selectivity. Chem. Biol. 10, 705-712 (Pubitemid 37089845)
    • (2003) Chemistry and Biology , vol.10 , Issue.8 , pp. 705-712
    • Scapin, G.1    Patel, S.B.2    Lisnock, J.3    Becker, J.W.4    LoGrasso, P.V.5
  • 43
    • 0029939283 scopus 로고    scopus 로고
    • Interpretation of deviations from pseudo-first-order kinetic behavior in the characterization of ligand binding by biosensor technology
    • DOI 10.1006/abio.1996.0167
    • O'Shannessy, D. J., and Winzor, D. J. (1996) Interpretation of deviations from pseudo-first order kinetic behavior in the characterization of ligand binding by biosensor technology. Anal. Biochem. 236, 275-283 (Pubitemid 26136106)
    • (1996) Analytical Biochemistry , vol.236 , Issue.2 , pp. 275-283
    • O'Shannessy, D.J.1    Winzor, D.J.2
  • 44
    • 43049120226 scopus 로고    scopus 로고
    • Determining kinetics and affinities of protein interactions using a parallel real-time label-free biosensor, the Octet
    • Abdiche, Y., Malashock, D., Pinkerton, A., and Pons, J. (2008) Determining kinetics and affinities of protein interactions using a parallel real-time label-free biosensor, the Octet. Anal. Biochem. 377, 209-217
    • (2008) Anal. Biochem. , vol.377 , pp. 209-217
    • Abdiche, Y.1    Malashock, D.2    Pinkerton, A.3    Pons, J.4
  • 45
    • 0018882953 scopus 로고
    • The use of the avidin-biotin complex as a tool in molecular biology
    • Bayer, E. A., and Wilchek, M. (1980) The use of the avidin-biotin complex as a tool in molecular biology. Methods Biochem. Anal. 26, 1-45
    • (1980) Methods Biochem. Anal. , vol.26 , pp. 1-45
    • Bayer, E.A.1    Wilchek, M.2
  • 50
    • 24944490193 scopus 로고    scopus 로고
    • The ERK cascade: A prototype of MAPK signaling
    • DOI 10.1385/MB:31:2:151
    • Rubinfeld, H., and Seger, R. (2005) The ERK cascade. A prototype of MAPK signaling. Mol. Biotechnol. 31, 151-174 (Pubitemid 41306584)
    • (2005) Molecular Biotechnology , vol.31 , Issue.2 , pp. 151-174
    • Rubinfeld, H.1    Seger, R.2
  • 51
    • 78951491639 scopus 로고    scopus 로고
    • Quantitative analysis of ERK2 interactions with substrate proteins. Roles for kinase docking domains and activity in determining binding affinity
    • Burkhard, K. A., Chen, F., and Shapiro, P. (2011) Quantitative analysis of ERK2 interactions with substrate proteins. Roles for kinase docking domains and activity in determining binding affinity. J. Biol. Chem. 286, 2477-2485
    • (2011) J. Biol. Chem. , vol.286 , pp. 2477-2485
    • Burkhard, K.A.1    Chen, F.2    Shapiro, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.