Structural basis for dual inhibitory role of tamarind Kunitz inhibitor (TKI) against factor Xa and trypsin

FEBS Journal

Volumn 279, Issue 24, 2012, Pages 4547-4564

  Patil, Dipak N ^a   Chaudhary, Anshul ^a   Sharma, Ashwani K ^a   Tomar, Shailly ^a   Kumar, Pravindra ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

Author keywords

factor Xa inhibitor; protein protein interaction; tamarind Kunitz type inhibitor; versatile reactive site; X ray structure

Indexed keywords

ARGININE; ASPARAGINE; BLOOD CLOTTING FACTOR 10A; TAMARIND KUNITZ INHIBITOR; TRYPSIN; TRYPSIN INHIBITOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BLOOD CLOTTING TIME; COMPLEX FORMATION; CRYSTAL STRUCTURE; MOLECULAR INTERACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; TAMARIND;

AMINO ACID SEQUENCE; FACTOR XA; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEASE INHIBITORS; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; TRYPSIN INHIBITORS;

GLYCINE MAX; LOTUS; SUS; TAMARINDUS INDICA;

EID: 84870509033     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12042     Document Type: Article

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