Suppression of urokinase expression and invasion by a soybean Kunitz trypsin inhibitor are mediated through inhibition of Src-dependent signaling pathways

Journal of Biological Chemistry

Volumn 280, Issue 36, 2005, Pages 31428-31437

  Inagaki, Kiyokazu ^a   Kobayashi, Hiroshi ^b   Yoshida, Ryuji ^c   Kanada, Yasufumi ^c   Fukuda, Yoichi ^c   Yagyu, Tatsno ^a   Kondo, Toshiharu ^d   Kurita, Noriyuki ^e   Kitanaka, Takashi ^f   Yamada, Yoshihiko ^f   Sakamoto, Yoshiharu ^f   Suzuki, Mika ^b   Kanayama, Naohiro ^b   Terao, Toshihiko ^b  

^a NetForce Co Ltd   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c FUJI OIL CO LTD   (Japan)

^d Computer Technology Integration Co Ltd ^*  (Japan)

^e TOYOHASHI UNIVERSITY OF TECHNOLOGY   (Japan)

^f NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION; GENETIC ENGINEERING;

CONSTITUTIVELY ACTIVE (CA); KUNITZ TRYPSIN INHIBITOR (KTI); UROKINASE EXPRESSION; UROKINASE-TYPE PLASMINOGEN ACTIVATOR (UPA);

ENZYMES;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; APROTININ; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; TRANSFORMING GROWTH FACTOR BETA1; TRYPSIN INHIBITOR; UROKINASE; UROKINASE RECEPTOR; WORTMANNIN;

ARTICLE; CELL INVASION; CONTROLLED STUDY; GENE; GENETIC ANALYSIS; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; REGULATORY MECHANISM; SOYBEAN; UPA GENE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL LINE, TUMOR; ENZYME REPRESSION; FEMALE; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; SIGNAL TRANSDUCTION; SOYBEANS; SRC-FAMILY KINASES; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRYPSIN INHIBITOR, KUNITZ SOYBEAN; UP-REGULATION; URINARY PLASMINOGEN ACTIVATOR;

GLYCINE MAX;

EID: 24744445796     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M501406200     Document Type: Article

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