A new Factor Xa inhibitor from Amblyomma cajennense with a unique domain composition

Archives of Biochemistry and Biophysics

Volumn 493, Issue 2, 2010, Pages 151-156

  Batista, I F C ^a   Ramos, O H P ^a   Ventura, J S ^a   Junqueira de Azevedo, I L M ^a   Ho, P L ^a   Chudzinski Tavassi, A M ^a  

^a INSTITUTO BUTANTAN   (Brazil)

Author keywords

Anticoagulant; FXa inhibitor; Kunitz; Molecular dynamics; Molecular modeling

Indexed keywords

AMBLYOMIN X; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 10A INHIBITOR; COMPLEMENTARY DNA; UNCLASSIFIED DRUG;

AMBLYOMMA; AMBLYOMMA CAJENNENSE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD CLOTTING TIME; CARBOXY TERMINAL SEQUENCE; CHEMICAL COMPOSITION; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; ESCHERICHIA COLI; EX VIVO STUDY; FEMALE; MOLECULAR CLONING; MOLECULAR DYNAMICS; MOLECULAR MODEL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTHROMBIN TIME; SEQUENCE ANALYSIS;

ANIMALS; CLONING, MOLECULAR; DNA, COMPLEMENTARY; FACTOR XA; HUMANS; IXODIDAE; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

AMBLYOMMA CAJENNENSE; ESCHERICHIA COLI; IXODIDA;

EID: 72949116561     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2009.10.009     Document Type: Article

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