-
1
-
-
77952555038
-
Exciting new advances in neurooncology: The avenue to a cure for malignant glioma
-
VanMeir E, Hadjipanayis C, Norden A, Shu H,Wen P, Olson J. Exciting new advances in neurooncology: the avenue to a cure for malignant glioma. CA Cancer J Clin 2010; 60: 166-193.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 166-193
-
-
Vanmeir, E.1
Hadjipanayis, C.2
Norden, A.3
Shu, H.4
Wen, P.5
Olson, J.6
-
2
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason W, van den Bent M, Weller M, Fisher B, Taphoorn M et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005; 352: 987-996.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.2
Van Den Bent, M.3
Weller, M.4
Fisher, B.5
Taphoorn, M.6
-
3
-
-
33748043985
-
Temozolomidemediated radiation enhancement in glioblastoma: A report on underlying mechanisms
-
Chakravarti A, Erkkinen M, Nestler U, Stupp R, Mehta M, Aldape K et al. Temozolomidemediated radiation enhancement in glioblastoma: a report on underlying mechanisms. Clin Cancer Res 2006; 12: 4738-4746.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4738-4746
-
-
Chakravarti, A.1
Erkkinen, M.2
Nestler, U.3
Stupp, R.4
Mehta, M.5
Aldape, K.6
-
4
-
-
33845931293
-
Fractionated ionizing radiation exposure induces apoptosis through caspase-3 activation and reactive oxygen species generation
-
Bucci B, Misiti S, Cannizzaro A, Marchese R, Raza G, Miceli R et al. Fractionated ionizing radiation exposure induces apoptosis through caspase-3 activation and reactive oxygen species generation. Anticancer Res 2006; 26: 4549-4557.
-
(2006)
Anticancer Res
, vol.26
, pp. 4549-4557
-
-
Bucci, B.1
Misiti, S.2
Cannizzaro, A.3
Marchese, R.4
Raza, G.5
Miceli, R.6
-
5
-
-
0037428798
-
Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids
-
Günther W, Pawlak E, Damasceno R, Arnold H, Terzis A. Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids. Br J Cancer 2007; 88: 463-469.
-
(2007)
Br J Cancer
, vol.88
, pp. 463-469
-
-
Günther, W.1
Pawlak, E.2
Damasceno, R.3
Arnold, H.4
Terzis, A.5
-
6
-
-
0842281645
-
Cell death: Critical control points
-
Danial N, Korsmeyer S. Cell death: critical control points. Cell 2004; 116: 205-219.
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.1
Korsmeyer, S.2
-
7
-
-
34247533289
-
Bax activation and mitochondrial insertion during apoptosis
-
Lalier L, Cartron P, Juin P, Nedelkina S, Manon S, Bechinger B et al. Bax activation and mitochondrial insertion during apoptosis. Apoptosis 2007; 12: 887-896.
-
(2007)
Apoptosis
, vol.12
, pp. 887-896
-
-
Lalier, L.1
Cartron, P.2
Juin, P.3
Nedelkina, S.4
Manon, S.5
Bechinger, B.6
-
8
-
-
33745957572
-
Proapoptotic multidomain Bcl-2/Bax-family proteins: Mechanisms, physiological roles, and therapeutic opportunities
-
Reed J. Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities. Cell Death Differ 2006; 13: 1378-1386.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1378-1386
-
-
Reed, J.1
-
10
-
-
33646354381
-
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
-
Certo M, Del Gaizo Moore V, Nishino M, Wei G, Korsmeyer S, Armstrong S et al. Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members. Cancer Cell 2006; 9: 351-365.
-
(2006)
Cancer Cell
, vol.9
, pp. 351-365
-
-
Certo, M.1
Del Gaizo Moore, V.2
Nishino, M.3
Wei, G.4
Korsmeyer, S.5
Armstrong, S.6
-
11
-
-
17044421611
-
Bcl-2 expression in acute myelogenous leukemia: The relation to myeloid antigen expression and response to therapy in Iranian patients
-
Daneshbod Y, Amirghofran Z, Tabei S. Bcl-2 expression in acute myelogenous leukemia: the relation to myeloid antigen expression and response to therapy in Iranian patients. Neoplasma 2005; 52: 109-114.
-
(2005)
Neoplasma
, vol.52
, pp. 109-114
-
-
Daneshbod, Y.1
Amirghofran, Z.2
Tabei, S.3
-
12
-
-
0037608711
-
Chemotherapy-induced apoptosis and Bcl-2 levels correlate with breast cancer response to chemotherapy
-
Buchholz T, Davis D, McConkey D, Symmans W, Valero V, Jhingran A et al. Chemotherapy-induced apoptosis and Bcl-2 levels correlate with breast cancer response to chemotherapy. Cancer J 2003; 9: 33-41.
-
(2003)
Cancer J
, vol.9
, pp. 33-41
-
-
Buchholz, T.1
Davis, D.2
McConkey, D.3
Symmans, W.4
Valero, V.5
Jhingran, A.6
-
13
-
-
77955801655
-
Expression of Bcl-2 family proteins and association with clinicopathological characteristics of oral squamous cell carcinoma
-
Coutinho-Camillo C, Lourenço S, Nishimoto I, Kowalski L, Soares F. Expression of Bcl-2 family proteins and association with clinicopathological characteristics of oral squamous cell carcinoma. Histopathology 2010; 57: 304-316.
-
(2010)
Histopathology
, vol.57
, pp. 304-316
-
-
Coutinho-Camillo, C.1
Lourenço, S.2
Nishimoto, I.3
Kowalski, L.4
Soares, F.5
-
14
-
-
80053018164
-
The role of BH3-Only proteins in tumor cell development, signaling, and treatment
-
Elkholi R, Floros K, Chipuk J. The role of BH3-Only proteins in tumor cell development, signaling, and treatment. Genes Cancer 2011; 2: 523-537.
-
(2011)
Genes Cancer
, vol.2
, pp. 523-537
-
-
Elkholi, R.1
Floros, K.2
Chipuk, J.3
-
15
-
-
0036097786
-
Keeping killers on a tight leash: Transcriptional and posttranslational control of the pro-apoptotic activity of BH3-only proteins
-
Puthalakath H, Strasser A. Keeping killers on a tight leash: transcriptional and posttranslational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ 2002; 9: 505-512.
-
(2002)
Cell Death Differ
, vol.9
, pp. 505-512
-
-
Puthalakath, H.1
Strasser, A.2
-
16
-
-
32844469134
-
Posttranslational modifications of Bcl2 family members - A potential therapeutic target for human malignancy
-
Basu A, DuBois G, Haldar S. Posttranslational modifications of Bcl2 family members - a potential therapeutic target for human malignancy. Front Biosci 2006; 11: 1508-1521.
-
(2006)
Front Biosci
, vol.11
, pp. 1508-1521
-
-
Basu, A.1
Dubois, G.2
Haldar, S.3
-
17
-
-
1842333237
-
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
-
del Peso L, González-García M, Page C, Herrera R, Nuñez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 1997; 278: 687-689.
-
(1997)
Science
, vol.278
, pp. 687-689
-
-
Del Peso, L.1
González-García, M.2
Page, C.3
Herrera, R.4
Nuñez, G.5
-
18
-
-
0038482050
-
Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim
-
Ley R, Balmanno K, Hadfield K, Weston C, Cook S. Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. J Biol Chem 2003; 278: 18811-18816.
-
(2003)
J Biol Chem
, vol.278
, pp. 18811-18816
-
-
Ley, R.1
Balmanno, K.2
Hadfield, K.3
Weston, C.4
Cook, S.5
-
19
-
-
13644254794
-
Molecular mechanisms of drug resistance
-
Longley D, Johnston P. Molecular mechanisms of drug resistance. J Pathol 2005; 205: 275-292.
-
(2005)
J Pathol
, vol.205
, pp. 275-292
-
-
Longley, D.1
Johnston, P.2
-
20
-
-
0027725154
-
Comparison between western blotting, immunohistochemical and ELISA assay for p185neu quantitation in breast cancer specimens
-
Dittadi R, Catozzi L, Gion M, Brazzale A, Capitanio G, Gelli M et al. Comparison between western blotting, immunohistochemical and ELISA assay for p185neu quantitation in breast cancer specimens. Anticacer res 1993; 13: 1821-1824.
-
(1993)
Anticacer Res
, vol.13
, pp. 1821-1824
-
-
Dittadi, R.1
Catozzi, L.2
Gion, M.3
Brazzale, A.4
Capitanio, G.5
Gelli, M.6
-
21
-
-
0034917808
-
Expression of bcl-2, bax and bcl-xl in human gliomas: A re-appraisal
-
Martin S, Toquet C, Oliver L, Cartron P, Perrin P, Meflah K et al. Expression of bcl-2, bax and bcl-xl in human gliomas: a re-appraisal. J Neurooncol 2001; 52: 129-139.
-
(2001)
J Neurooncol
, vol.52
, pp. 129-139
-
-
Martin, S.1
Toquet, C.2
Oliver, L.3
Cartron, P.4
Perrin, P.5
Meflah, K.6
-
22
-
-
38149096186
-
Bim expression is reduced in human cutaneous melanomas
-
Dai D, Wang Y, Liu M, Martinka M, Li G. Bim expression is reduced in human cutaneous melanomas. J Invest Dermatol 2008; 128: 403-407.
-
(2008)
J Invest Dermatol
, vol.128
, pp. 403-407
-
-
Dai, D.1
Wang, Y.2
Liu, M.3
Martinka, M.4
Li, G.5
-
23
-
-
48249116801
-
Proapoptotic Bad and Bid protein expression predict survival in stages II and III colon cancers
-
Sinicrope F, Rego R, Foster N, Thibodeau S, Alberts S, Windschitl H et al. Proapoptotic Bad and Bid protein expression predict survival in stages II and III colon cancers. Clin Cancer Res 2008; 14: 4128-4133.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4128-4133
-
-
Sinicrope, F.1
Rego, R.2
Foster, N.3
Thibodeau, S.4
Alberts, S.5
Windschitl, H.6
-
24
-
-
53249088373
-
Prognostic impact of bim, puma, and noxa expression in human colon carcinomas
-
Sinicrope F, Rego R, Okumura K, Foster N, O'Connell M, Sargent D et al. Prognostic impact of bim, puma, and noxa expression in human colon carcinomas. Clin Cancer Res 2008; 14: 5810-5818.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5810-5818
-
-
Sinicrope, F.1
Rego, R.2
Okumura, K.3
Foster, N.4
O'Connell, M.5
Sargent, D.6
-
25
-
-
79953067256
-
Impact of the DNA methyltransferases expression on the methylation status of apoptosis-associated genes in glioblastoma multiforme
-
Hervouet E, Vallette F, Cartron P. Impact of the DNA methyltransferases expression on the methylation status of apoptosis-associated genes in glioblastoma multiforme. Cell Death Dis 2010; 1: e8.
-
(2010)
Cell Death Dis
, vol.1
-
-
Hervouet, E.1
Vallette, F.2
Cartron, P.3
-
26
-
-
34547933338
-
Reciprocal protection of Mcl-1 and Bim from ubiquitin-proteasome degradation
-
Wuilleme-Toumi S, Trichet V, Gomez-Bougie P, Gratas C, Bataille R, Amiot M. Reciprocal protection of Mcl-1 and Bim from ubiquitin-proteasome degradation. Biochem Biophys Res Commun 2007; 361: 865-869.
-
(2007)
Biochem Biophys Res Commun
, vol.361
, pp. 865-869
-
-
Wuilleme-Toumi, S.1
Trichet, V.2
Gomez-Bougie, P.3
Gratas, C.4
Bataille, R.5
Amiot, M.6
-
27
-
-
0242410719
-
P53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
-
Villunger A, Michalak E, Coultas L, Müllauer F, Böck G, Ausserlechner M et al. p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 2003; 302: 1036-1038.
-
(2003)
Science
, vol.302
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.2
Coultas, L.3
Müllauer, F.4
Böck, G.5
Ausserlechner, M.6
-
28
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T, Reed J. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1999; 80: 293-299.
-
(1999)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.2
-
29
-
-
78650510699
-
O6-methylguanine DNA methyltransferase gene promoter methylation status in gliomas and its correlation with other molecular alterations: First Indian report with review of challenges for use in customized treatment
-
Jha P, Suri V, Jain A, Sharma M, Pathak P, Jha P et al. O6-methylguanine DNA methyltransferase gene promoter methylation status in gliomas and its correlation with other molecular alterations: first Indian report with review of challenges for use in customized treatment. Neurosurgery 2010; 67: 1681-1691.
-
(2010)
Neurosurgery
, vol.67
, pp. 1681-1691
-
-
Jha, P.1
Suri, V.2
Jain, A.3
Sharma, M.4
Pathak, P.5
Jha, P.6
-
30
-
-
73349103157
-
Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: A prospective translational study of the German Glioma Network
-
Weller M, Felsberg J, Hartmann C, Berger H, Steinbach J, Schramm J et al. Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network. J Clin Oncol 2009; 27: 5743-5750.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5743-5750
-
-
Weller, M.1
Felsberg, J.2
Hartmann, C.3
Berger, H.4
Steinbach, J.5
Schramm, J.6
-
31
-
-
79952195737
-
MGMT promoter hypermethylation is a frequent, early, and consistent event in astrocytoma progression, and not correlated with TP53 mutation
-
Groenendijk F, Taal W, Dubbink H, Haarloo C, Kouwenhoven M, van den Bent M et al. MGMT promoter hypermethylation is a frequent, early, and consistent event in astrocytoma progression, and not correlated with TP53 mutation. J Neurooncol 2011; 101: 405-417.
-
(2011)
J Neurooncol
, vol.101
, pp. 405-417
-
-
Groenendijk, F.1
Taal, W.2
Dubbink, H.3
Haarloo, C.4
Kouwenhoven, M.5
Van Den Bent, M.6
-
32
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, Goodman SN, Hidalgo OF, Vanaclocha V et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 2000; 343: 1350-1354.
-
(2000)
N Engl J Med
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
Goodman, S.N.4
Hidalgo, O.F.5
Vanaclocha, V.6
|