Mapping spatial approximations between the amino terminus of secretin and each of the extracellular loops of its receptor using cysteine trapping

FASEB Journal

Volumn 26, Issue 12, 2012, Pages 5092-5105

  Dong, Maoqing ^a   Xu, Xiequn ^a,f   Ball, Alicja M ^a   Makhoul, Joshua A ^a   Lam, Polo C H ^b   Pinon, Delia I ^a   Orry, Andrew ^b   Sexton, Patrick M ^c,d   Abagyan, Ruben ^b,d,e   Miller, Laurence J ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b MOLSOFT LLC   (United States)

^c MONASH UNIVERSITY   (Australia)

^d MONASH UNIVERSITY   (Australia)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

Class B GPCRs; Ligand binding; Molecular modeling

Indexed keywords

CYSTEINE; SECRETIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CONTROLLED STUDY; DISULFIDE BOND; EXTRACELLULAR LOOP; FEMALE; FLOW CYTOMETRY; MOLECULAR DYNAMICS; MUTAGENESIS; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE;

ANIMALS; BINDING, COMPETITIVE; CERCOPITHECUS AETHIOPS; CHO CELLS; COS CELLS; CRICETINAE; CRICETULUS; CYSTEINE; DISULFIDES; HUMANS; LIGANDS; MODELS, MOLECULAR; MUTATION; PEPTIDES; PHENYLALANINE; PROLINE; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, GASTROINTESTINAL HORMONE; SECRETIN; TRYPTOPHAN;

RUMEX;

EID: 84870352082     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-212399     Document Type: Article

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