Spatial proximity between the VPAC1 receptor and the amino terminus of agonist and antagonist peptides reveals distinct sites of interaction

FASEB Journal

Volumn 26, Issue 5, 2012, Pages 2060-2071

  Ceraudo, Emilie ^a   Hierso, Régine ^a   Tan, Yossan Var ^a   Murail, Samuel ^b   Rouyer Fessard, Christiane ^a   Nicole, Pascal ^a   Robert, Jean Claude ^a   Jamin, Nadège ^b   Neumann, Jean Michel ^b   Robberecht, Patrick ^c   Laburthe, Marc ^a   Couvineau, Alain ^a  

^a INSERM   (France)

^b SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

^c UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Binding site; GPCR; Inflammatory diseases; VIP

Indexed keywords

HISTIDINE; PG 97 269; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE ANTAGONIST; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CONTROLLED STUDY; HORMONE RECEPTOR INTERACTION; HUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE MAPPING; PEPTIDES; PHOTOAFFINITY LABELS; RECEPTORS, VASOACTIVE INTESTINAL POLYPEPTIDE, TYPE I; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84860908751     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-196444     Document Type: Article

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