Three distinct epitopes on the extracellular face of the glucagon receptor determine specificity for the glucagon amino terminus

Journal of Biological Chemistry

Volumn 278, Issue 30, 2003, Pages 28005-28010

  Runge, Steffen ^a,b   Gram, Christian ^a,b   Bräuner Osborne, Hans ^a   Madsen, Kjeld ^a   Knudsen, Lotte B ^a   Wulff, Birgitte S ^a  

^a NOVO NORDISK A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; HORMONES; MEMBRANES; PROTEINS;

PROTEIN-COUPLED RECEPTORS;

BIOCHEMISTRY;

ALANINE; EPITOPE; GLUCAGON LIKE PEPTIDE 1; GLUCAGON RECEPTOR; GLUTAMINE; LYSINE; SERINE; TYROSINE; VALINE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; EMBRYO; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ASPARTIC ACID; CELL LINE; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITOPES; GENES, REPORTER; GLUCAGON; GLUTAMIC ACID; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, GLUCAGON; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0041344589     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M301085200     Document Type: Article

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