Therapeutic delivery of siRNA silencing HIF-1 alpha with micellar nanoparticles inhibits hypoxic tumor growth

Molecular Pharmaceutics

Volumn 9, Issue 10, 2012, Pages 2863-2874

  Liu, Xi Qiu ^a   Xiong, Meng Hua ^a   Shu, Xiao Ting ^a   Tang, Rui Zhi ^a   Wang, Jun ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COPOLYMER; DOXORUBICIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MICELLAR NANOPARTICLE; MULTIDRUG RESISTANCE PROTEIN 1; NANOPARTICLE; POLY(EPSILON CAPROLACTONE) BLOCK POLY (2 AMINOETHYLETHYLENE PHOSPHATE); POLY(EPSILON CAPROLACTONE) BLOCK POLY(ETHYLENE GLYCOL); SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL MIGRATION; CELL PROLIFERATION; CHEMICAL INTERACTION; CONTROLLED STUDY; DOWN REGULATION; DRUG DELIVERY SYSTEM; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; TUMOR GENE; TUMOR MICROENVIRONMENT; TUMOR VOLUME; TUMOR XENOGRAFT;

EID: 84870197971     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300193f     Document Type: Article

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