Novel biodegradable polylactide/poly(ethylene glycol) micelles prepared by direct dissolution method for controlled delivery of anticancer drugs

Pharmaceutical Research

Volumn 26, Issue 10, 2009, Pages 2332-2342

  Yang, Liu ^a,b   Wu, Xiaohan ^a   Liu, Feng ^a   Duan, Yourong ^c   Li, Suming ^a,b  

^a FUDAN UNIVERSITY   (China)

^b UNIVERSITÉ DE MONTPELLIER   (France)

^c SHANGHAI CANCER INSTITUTE   (China)

Author keywords

Drug delivery; Micelle; Paclitaxel; Poly(ethylene glycol); Polylactide

Indexed keywords

MACROGOL; PACLITAXEL; POLYLACTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIODEGRADABILITY; COMPLEX FORMATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG RELEASE; ENCAPSULATION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBICITY; LIGHT SCATTERING; LUNG CANCER; MICELLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOCOMPATIBLE MATERIALS; CARCINOMA, LEWIS LUNG; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; MICE; MICE, INBRED C57BL; MICELLES; POLYESTERS; POLYETHYLENE GLYCOLS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 69949169645     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-9949-4     Document Type: Article

References (58)

1. MC Wani HL Taylor ME Wall P Coggon AT Mcphail 1971 Plant antitumor agents. VI. The isolation and structure of Taxol, a novel antileukemic and antitumor agent from Taxus brevifolia J Am Chem Soc. 93 2325 2327
2. PB Schiff J Fant SB Horwitz 1979 Promotion of microtubule assembly in vitro by taxol Nature. 277 665 667
3. CM Spencer D Faulds 1994 Paclitaxel-a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of cancer Drugs. 48 794 847 (Pubitemid 24304427)
4. EM Wall MC Wan 1995 Camptothecin and Taxol: discovery to clinic Cancer Res. 55 753 760
5. JD Ohnson R Arriagada N Barthelemy J Bonner P Bonomi B Enami 1997 Post-operative adjuvant therapy for non-small-cell lung cancer Lung Cancer. 17 S23 S25
6. JH Kim K Emoto M Lijima Y Nagasaki T Aoyagi T Okano Y Sakurai K Kataoka 1999 Core-stabilized polymeric micelle as potential drug carrier: increased solubilization of Taxol Polym Adv Technol. 10 647 654
7. S Feng G Huang 2001 Effects of emulsifiers on the controlled release of paclitaxel (Taxol®) from nanospheres of biodegradable polymers J Control Release. 71 53 69
8. L Han J Guo L Zhang Q Wang X Fang 2006 Pharmacokinetics and biodistribution of polymeric micelles of paclitaxel with Pluronic P123 Acta Pharm Sini. 27 747 753
9. J Wang D Mongayt VP Torchilin 2005 Polymeric micelles for delivery of poorly soluble drugs: preparation and anticancer activity in vitro of paclitaxel incorporated into mixed micelles based on poly(ethylene glycol)-lipid conjugate and positively charged lipids J Drug Targ. 13 73 80 (Pubitemid 40309464)
10. KM Huh HS Min SC Lee HJ Lee S Kim K Park 2008 A new hydrotropic block copolymer micelle system for aqueous solubilization of paclitaxel J Control Release. 126 122 129
11. P Kan ZB Chen CJ Lee IM Chu 1999 Development of nonionic surfactant/phospholipid o/w emulsion as a paclitaxel delivery system J Control Release. 58 271 278
12. P Crosasso M Ceruti P Brusa S Arpicco F Dosio L Cattel 2000 Preparation, characterization and properties of sterically stabilized paclitaxel-containing liposomes J Control Release. 63 19 30
13. S Li B Byrne J Welsh AF Palmer 2007 Self-assembled poly (butadiene)-b-poly(ethylene oxide) polymersomes as paclitaxel carriers Biotechnol Prog. 2 278 285
14. C Fonseca S Simoes R Gaspar 2002 Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity J Control Release. 83 273 286
15. Y Dong SS Feng 2004 Methoxy poly(ethylene glycol)-poly(lactide) (MPEG-PLA) nanoparticles for controlled delivery of anticancer drugs Biomaterials. 25 2843 2849
16. J Xie CH Wang 2005 Self-assembled biodegradable nanoparticles developed by direct dialysis for the delivery of paclitaxel Pharm Res. 22 2079 2090
17. P Jie SS Venkatraman F Min BYC Freddy GL Huat 2005 Micelle-like nanoparticles of star-branched PEO-PLA copolymers as chemotherapeutic carrier J Control Release. 110 20 33 (Pubitemid 41713928)
18. Z Zhang SS Feng 2006 Nanoparticles of poly(lactide)/vitamin E TPGS copolymer for cancer chemotherapy: synthesis, formulation, characterization and in vitro drug release Biomaterials. 27 262 270
19. Z Zhang SS Feng 2006 The drug encapsulation efficiency, in vitro drug release, cellular uptake and cytotoxicity of paclitaxel-loaded poly(lactide)-tocopheryl polyethylene glycol succinate nanoparticles Biomaterials. 27 4025 4033
20. RT Liggins S D'Amours JS Demetrick LS Machan HM Burt 2000 Paclitaxel loaded poly(L-lactic acid) microspheres for the prevention of intraperitoneal carcinomatosis after a surgical repair and tumor cell spill Biomaterials. 21 1959 1969
21. GS Das GHR Rao RF Wilson T Chandy 2001 Controlled delivery of taxol from poly(ethylene glycol)-coated poly(lactic acid) microspheres J Biomed Mater Res. 55 96 103
22. SY Kim YM Lee 2001 Taxol-loaded block copolymer nanospheres composed of methoxy poly(ethylene glycol) and poly(ε-caprolactone) as novel anticancer drug carriers Biomaterials. 22 1697 1704
23. SY Kim YM Lee DJ Baik JS Kang 2003 Toxic characteristics of methoxy poly(ethylene glycol)/poly(ε-caprolactone) nanospheres: in vitro and in vivo studies in the normal mice Biomaterials. 24 55 63
24. G Ruan SS Feng 2003 Preparation and characterization of poly(lactic acid)-poly(ethylene glycol)-poly(lactic acid) (PLA-PEG-PLA) microspheres for controlled release of paclitaxel Biomaterials. 24 5037 5044
25. EK Park SB Lee YM Lee 2005 Preparation and characterization of methoxy poly(ethylene glycol)/poly(ε-caprolactone) amphiphilic block copolymeric nanospheres for tumor-specific folate-mediated targeting of anticancer drugs Biomaterials. 26 1053 1061
26. H Alkan-Onyuksel S Ramakrishnan HB Chai JM Pezzuto 1994 A mixed micellar formulation suitable for the parenteral administration of Taxol Pharm Res. 11 206 212
27. A Miwa A Ishibe M Nakano T Yamahira S Itai S Jinno H Kawahara 1998 Development of novel chitosan derivatives as micellar carriers of Taxol Pharm Res. 15 1844 1850
28. RT Liggins HM Burt 2002 Polyether-polyester diblock copolymers for the preparation of paclitaxel loaded polymeric micelle formulations Adv Drug Deliv Rev. 54 191 202
29. O Soga CF van Nostrum M Fens CJF Rijcken RM Schiffelers G Storm WE Hennink 2005 Thermosensitive and biodegradable polymeric micelles for paclitaxel delivery J Control Release. 103 341 353
30. S Cai K Vijayan D Cheng EM Lima DE Discher 2007 Micelles of different morphologies-advantages of worm-like filomicelles of PEO-PCL in paclitaxel delivery Pharm Res. 24 2099 2109
31. T Ooya KM Huh M Saitoh E Tamiya K Park 2005 Self-assembly of cholesterol-hydrotropic dendrimer conjugates into micelle-like structure: preparation and hydrotropic solubilization of paclitaxel Sci Technol Adv Mater. 6 452 456
32. Z Xie T Lu X Chen C Lu Y Zheng X Jing 2007 Triblock poly(lactic acid)-b-poly(ethylene glycol)-b-poly(lactic acid)/paclitaxel conjugates: synthesis, micellization, and cytotoxicity J Appl Polym Sci. 105 2271 2279
33. Z Xie H Guan X Chen C Lu L Chen X Hu Q Shi X Jing 2007 A novel polymer-paclitaxel conjugate based on amphiphilic triblock copolymer J Control Release. 117 210 216
34. GS Kwon K Kataoka 1995 Block copolymer micelles as long-circulating drug vehicles Adv Drug Deliv Rev. 16 295 309
35. GS Kwon T Okano 1996 Polymeric micelles as new drug carriers Adv Drug Deliv Rev. 21 107 116
36. K Kataoka A Harada Y Nagasaki 2001 Block copolymer micelles for drug delivery: design, characterization and biological significance Adv Drug Deliv Rev. 47 113 131
37. L Liu C Li X Li Z Yuan Y An B He 2001 Biodegradable polylactide/ poly(ethylene glycol)/polylactide triblock copolymer micelles as anticancer drug carriers J Appl Polym Sci. 80 1976 1982
38. X Shuai T Merdan AK Schaper F Xi T Kissel 2004 Core-cross-linked polymeric micelles as paclitaxel carriers Bioconjugate Chem. 15 441 448
39. T Hamaguchi Y Matsumura M Suzuki K Shimizu R Goda I Nakamura I Nakatomi M Yokoyama K Kataoka T Kakizoe 2005 NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduced the neurotoxicity of paclitaxel Brit J Canc. 92 1240 1246
40. SA Hagan AGA Coombes MC Garnett SE Dunn MC Davies L Illum SS Davis SE Harding S Purkiss PP Gellert 1996 Polylactide-poly(ethylene glycol) copolymers as drug delivery systems. 1. Characterization of water dispersible micelle-forming systems Langmuir. 12 2153 2161
41. HM Burt X Zhang P Toleikis L Embree WL Hunter 1999 Development of copolymers of poly(D, L-lactide) and methoxypolyethylene glycol as micellar carriers of paclitaxel Colloids Surf B: Biointerfaces. 16 161 171
42. E Pierri K Avgoustakis 2005 Poly(lactide)-poly(ethylene glycol) micelles as a carrier for griseofulvin J Biomed Mater Res. 75A 639 647
43. SY Kim JH Kim D Kim JH An DS Lee SC Kim 2001 Drug-releasing kinetics of MPEG/PLLA block copolymer micelles with different PLLA block lengths J Appl Polym Sci. 82 2599 2605
44. E Blanco EA Bey Y Dong BD Weinberg DM Sutton DA Boothman J Gao 2007 β-Lapachone-containing PEG-PLA polymer micelles as novel nanotherapeutics against NQO1-overexpressing tumor cells J Control Release. 122 365 374
45. SC Kim DW Kim YH Shim JS Bang HS Oh SW Kim MH Seo 2001 In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy J Control Release. 72 191 202
46. TY Kim DW Kim JY Chung SG Shin SC Kim DS Heo NK Kim YJ Bang 2004 Phase I and pharmacokinetic study of Genexol-PM, a Cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies Clinical Cancer Res. 10 3708 3716
47. KS Lee HG Chung SA Im YH Park CS Kim SB Kim SY Rha MY Lee J Ro 2008 Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer Breast Cancer Res Treat. 108 241 250
48. X Zhang JK Jackson HM Burt 1996 Development of amphiphilic diblock copolymers as micellar carriers of taxol Int J Pharm. 132 195 206
49. T Riley T Govender S Stolnik CD Xiong MC Garnett L Illum SS Davis 1999 Colloidal stability and drug incorporation aspects of micellar-like PLA-PEG nanoparticles Colloids Surf B: Biointerfaces. 16 147 159
50. K Yasugi Y Nagasaki M Kato K Kataoka 1999 Preparation and characterization of polymer micelles from poly(ethylene glycol)-poly(D, L-lactide) block copolymers as potential drug carrier J Control Release. 62 89 100
51. SS Venkatraman P Jie F Min BYC Freddy G Leong-Huat 2005 Micelle-like nanoparticles of PLA-PEG-PLA triblock copolymer as chemotherapeutic carrier Int J Pharm. 298 219 232 (Pubitemid 40828343)
52. L Yang Z Zhao J Wei AE Ghzaoui S Li 2007 Micelles formed by self-assembling of polylactide/poly(ethylene glycol) block copolymers in aqueous solutions J Colloid Interf Sci. 314 470 477
53. C Allen D Maysinger A Eisenberg 1999 Nano-engineering block copolymer aggregates for drug delivery Colloids Surf B: Biointerfaces. 16 3 27
54. G Gaucher MH Dufresne VP Sant N Kang D Maysinger JC Leroux 2005 Block copolymer micelles: preparation, characterization and application in drug delivery J Control Release. 109 169 188
55. S Li M Vert 2003 Synthesis, characterization, and stereocomplex-induced gelation of block copolymers prepared by ring-opening polymerization of L(D)-lactide in the presence of poly(ethylene glycol) Macromolecules. 36 8008 8014
56. N Kang ME Perron RE Prud'homme Y Zhang G Gaucher JC Leroux 2005 Stereocomplex block copolymer micelles: core-shell nanostructures with enhanced stability Nano Lett. 5 315 319
57. Z Dai L Piao X Zhang M Deng X Chen X Jing 2004 Probing the micellization of diblock and triblock copolymers of poly(L-lactide) and poly(ethylene glycol) in aqueous and NaCl salt solutions Colloid Polym Sci. 282 343 350
58. SK Agrawal N Sanabria-DeLong JM Coburn GN Tew SR Bhatia 2006 Novel drug release profiles from micellar solutions of PLA-PEO-PLA triblock copolymers J Control Release. 112 64 71