Rational design of conformationally constrained cyclopentapeptide antagonists for C-X-C chemokine receptor 4 (CXCR4)

Journal of Medicinal Chemistry

Volumn 55, Issue 22, 2012, Pages 10287-10291

  Mungalpara, Jignesh ^a   Thiele, Stefanie ^b   Eriksen, Øystein ^a   Eksteen, Johann ^a,c,d   Rosenkilde, Mette M ^b   Våbenø, Jon ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c LYTIX BIOPHARMA AS   (Norway)

^d Northern Research Institute Tromsø   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; CYCLOPENTAPEPTIDE AGONIST; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG BINDING; DRUG DESIGN; STRUCTURE ACTIVITY RELATION;

DRUG DESIGN; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PEPTIDES, CYCLIC; PEPTIDOMIMETICS; PROTEIN CONFORMATION; RECEPTORS, CXCR4;

EID: 84869990168     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300926y     Document Type: Article

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