Inhibition of EGF/EGFR activation with naphtho[1,2-b]furan-4,5-dione blocks migration and invasion of MDA-MB-231 cells

Toxicology in Vitro

Volumn 27, Issue 1, 2013, Pages 1-10

  Hsieh, Chi Ying ^a   Tsai, Pei Chien ^a   Tseng, Chih Hua ^a   Chen, Yeh long ^a   Chang, Long Sen ^b   Lin, Shinne Ren ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

EGF EGFR; MDA MB 231 cells; NFD; PI3K Akt

Indexed keywords

ANTIMETASTATIC AGENT; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE B; NAPHTH[1,2 B]FURAN 4,5 DIONE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN C FOS; PROTEIN C JUN; PROTEIN KINASE B; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ARTICLE; CELL INVASION; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; METASTASIS INHIBITION; MIGRATION INHIBITION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ANDROSTADIENES; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; EPIDERMAL GROWTH FACTOR; FEMALE; HUMANS; MATRIX METALLOPROTEINASE 9; NAPHTHOQUINONES; NEOPLASM INVASIVENESS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; TRANSCRIPTION FACTOR AP-1; WOUND HEALING;

AVICENNIA MARINA;

EID: 84869424352     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.10.001     Document Type: Article

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