Bee venom suppresses PMA-mediated MMP-9 gene activation via JNK/p38 and NF-κB-dependent mechanisms

Journal of Ethnopharmacology

Volumn 127, Issue 3, 2010, Pages 662-668

  Cho, Hyun Ji ^a,b   Jeong, Yun Jeong ^a   Park, Kwan Kyu ^a   Park, Yoon Yub ^a   Chung, Il Kyung ^a   Lee, Kwang Gill ^c   Yeo, Joo Hong ^c   Han, Sang Mi ^c   Bae, Young Seuk ^b   Chang, Young Chae ^a  

^a Catholic University of Daegu   (South Korea)

^b Kyungpook National University   (South Korea)

^c National Institute of Animal Science   (South Korea)

Author keywords

Bee venom; MCF 7 cells; MMP 9; NF B; Phospho JNK; Phospho p38

Indexed keywords

ANTIMETASTATIC AGENT; APAMIN; BEE VENOM; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRIGEL; MELITTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPASE A2; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER INVASION; CELL INVASION; CELL MIGRATION; CELL STRAIN MCF 7; CELL VIABILITY; CONTROLLED STUDY; DRUG DNA BINDING; DRUG MECHANISM; DRUG SCREENING; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GEL MOBILITY SHIFT ASSAY; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE INACTIVATION; HUMAN; HUMAN CELL; METASTASIS; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ZYMOGRAPHY;

ANTINEOPLASTIC AGENTS; APITHERAPY; BEE VENOMS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DNA; FEMALE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MATRIX METALLOPROTEINASE 9; MELITTEN; NEOPLASM INVASIVENESS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTIONAL ACTIVATION;

APOIDEA;

EID: 76149144313     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.12.007     Document Type: Article

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