Furo[3′,2′:3,4]naphtho[1,2-d]imidazole derivatives as potential inhibitors of inflammatory factors in sepsis

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 18, 2009, Pages 6773-6779

  Tseng, Chih Hua ^a   Lin, Chang Sheng ^a   Shih, Pin Keng ^b   Tsao, Lo Ti ^c   Wang, Jih Pyang ^c   Cheng, Chih Mei ^a   Tzeng, Cherng Chyi ^a   Chen, Yeh Long ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Anti inflammatory; Furo 3 ,2 :3,4 naphtho 1,2 d imidazole; Inducible nitric; Nitric oxide; Oxide synthase; Sepsis

Indexed keywords

2 (4 FORMYLPHENYL)FURO[3',2':3,4]NAPTHO[1,2 D]IMIDAZOLE; 2 (4 NITROPHENYL)FURO[3',2':3,4]NAPHTHO[1,2 D]IMIDAZOLE; 2 (5 NITROFURAN 2 YL)FURO[3',2':3,4]NAPHTHO[1,2 D]IMIDAZOLE; 2 [2 (5 NITROFURAN 2 YL)VINYL]FURO[3',2':3,4]NAPHTHO[1,2 D]IMIDAZOLE; 2 FURANYLFURO[3',2':3,4]NAPHTHO[1,2 D]IMIDAZOLE; 2 PHENYLFURO[3',2':3,4]NAPHTHO[1,2 D]IMIDAZOLE; ANTIINFLAMMATORY AGENT; BENZENE DERIVATIVE; BETA GLUCURONIDASE; FURO[3',2':3,4]NAPHTHO[1,2 D]IMIDAZOLE DERIVATIVE; HYDROCORTISONE; INDUCIBLE NITRIC OXIDE SYNTHASE; LAWSONE; LYSOZYME; NAPHTHO[1,2 B]FURAN 4,5 DIONE; NITROFURAN; PROSTAGLANDIN E2; TRIFLUOPERAZINE; UNCLASSIFIED DRUG; FURAN; FURAN DERIVATIVE; IMIDAZOLE DERIVATIVE; NITRIC OXIDE; PROSTAGLANDIN E; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; NONHUMAN; RAT; SEPSIS; ANIMAL; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION; GENETICS; METABOLISM; NEUTROPHIL; SPRAGUE DAWLEY RAT;

ANIMALIA; RATTUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; FURANS; GENE EXPRESSION; IMIDAZOLES; NEUTROPHILS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PROSTAGLANDINS E; RATS; RATS, SPRAGUE-DAWLEY; SEPSIS; SUPEROXIDES;

EID: 69249129139     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.07.054     Document Type: Article

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