Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells

Cancer Research

Volumn 60, Issue 4, 2000, Pages 1121-1128

  O Charoenrat, Pornchai ^a,c,d   Modjtahedi, Helmout ^b   Rhys Evans, Peter ^c   Court, William J ^a   Box, Gary M ^a   Eccles, Suzanne A ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF SURREY   (United Kingdom)

^c ROYAL MARSDEN HOSPITAL   (United Kingdom)

^d MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIREGULIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE A; GELATINASE B; HEPARIN BINDING PROTEIN; LIGAND; ONCOPROTEIN; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CERVICAL LYMPH NODE; CONTROLLED STUDY; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; LYMPH NODE METASTASIS; ONCOGENE C ERB; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RECEPTOR DENSITY; SQUAMOUS CELL CARCINOMA;

ANTIBODIES, MONOCLONAL; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; EPIDERMAL GROWTH FACTOR; HEAD AND NECK NEOPLASMS; HUMANS; LIGANDS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0034652487     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Vokes, E. E., Weichselbaum, R. R., Lippman, S. M., and Hong, W. K. Head and neck cancer. N. Engl, J. Med., 328: 184-194, 1993.
2. Mork, J. Forty years of monitoring head and neck cancer in Norway: no good news. Anticancer Res., 18: 3705-3708, 1998.
3. Modjtahedi, H., and Dean, C. The receptor for EGF and its ligands: expression, prognostic value and target for therapy in cancer. Int. J. Oncol., 4: 277-296, 1994.
4. Issing, W. J., Liehich, C., Wustrow, T. P., and Ullrich, A. Coexpression of epidermal growth factor receptor and TGF-α and survival in upper aerodigestive tract cancer. Anticancer Res., 16: 283-288, 1996.
5. Grandis, J. R., Melhem, M. F., Gooding, W. E., Day, R., Holst, V. A., Wagener, M. M., Drenning, S. D., and Tweardy, D. J. Levels of TGF-α and EGFR protein in head and neck squamous cell carcinoma and patient survival. J. Natl. Cancer Inst., 90: 824-832, 1998.
6. Cohen, S. Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. J. Biol. Chem., 237: 1555-1562, 1962.
7. Todaro, G. J., De Larco, J. E., and Cohen, S. Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells. Nature (Lond.), 264: 26-31, 1976.
8. Shing, Y., Christofori, G., Hanahan, D., Ono, Y., Sasada, R., Igarashi, K., and Folkman, J. Betacellulin: a mitogen from pancreatic β cell tumors. Science (Washington DC), 259: 1604-1607, 1993.
9. Higashiyama, S., Abraham, J. A., Miller, J. L., Fiddes, J. C., and Klagsbrun. M. A heparin-binding growth factor secreted by macrophage-like cell that is related to EGF. Science (Washington DC), 251: 936-939, 1991.
10. Shoyab, M., McDonald, V. L., Bradley, G., and Todaro, G. T. Amphiregulin: a bifunctional growth-modulating glycoprolein produced by the phorbol 12-myristate-treated human breast adenocarcinoma cell line MCF-7. Proc. Natl. Acad. Sci. USA., 85: 6528-6532, 1988.
11. Toyoda, H., Komurasaki, T., Ikeda, Y., Yoshimoto, M., and Morimoto, S. Molecular cloning of mouse epiregulin, a novel epidermal growth factor-related protein, expressed in the early stage of development. FEBS Lett., 377: 403-407, 1995.
12. Shirasuna, K., Hayashido, Y., Sugiyama, M., Yoshioka, H., and Matsuya, T. Immunohistochemical localization of epidermal growth factor (EGF) and EGF receptor in human oral mucosa and its malignancy. Virchows Arch. A Pathol. Anat. Histopathol., 418: 349-353, 1991.
13. Prime, S. S., Game, S. M., Matthews, J. B., Stone, A., Donnelly, M. J., Yeudall, W. A., Patel, V., Sposto, R., Silverthorne, A., and Scully, C. Epidermal growth factor and transforming growth factor α characteristics of human oral carcinoma cell lines. Br. J. Cancer, 69: 8-15, 1994.
14. Liotta, A., and Stetler-Stevenson, W. G. Invasion and metastasis: an imbalance of positive and negative regulation. Cancer Res., 51 (Suppl.): 5054s-5059s, 1991.
15. Boyd, D. D., and Nicolson, G. L. Mechanisms of invasion by head and neck cancers. Cancer Treat Res., 74: 117-130, 1995.
16. Himelstein, B. P., Canete Soler, R., Bernhard, E. J., Dilks, D. W., and Muschel, R. J. Metalloproteinases in tumor progression: the contribution of MMP-9. Invasion Metastasis, 14: 246-258, 1994.
17. Jones, J. L., and Walker, R. A. Control of matrix metalloproteinase activity in cancer. J. Pathol., 183: 377-379, 1997.
18. Thomas, G. T., Lewis, M. P., and Speight, P. M. Matrix metalloproteinases and oral cancer. Oral Oncol., 35: 227-233, 1999.
19. Juarez, J., Clayman, G., Nakajima, M., Tanabe, K. K., Saya, H., Nicolson, G. L., and Boyd, D. Role and regulation of expression of 92-kDa type-IV collagenase (MMP-9) in 2 invasive squamous-cell-carcinoma cell lines of the oral cavity. Int. J. Cancer, 55: 10-18, 1993.
20. Kawamata, H., Uchida, D., Hamano, H., Kimura Yanagawa, T., Nakashiro, K. I., Hino, S., Omotehara, F., Yoshida, H., and Sato, M. Active-MMP2 in cancer cell nests of oral cancer patients: correlation with lymph node metastasis. Int. J. Oncol., 13: 699-704, 1998.
21. Cazorla, M., Hernandez, L., Nadal, A., Balbin, M., Lopez, J. M., Vizoso, F., Fernandez, P. L., Iwata, K., Cardesa, A., Lopez Otin, C., and Campo, E. Collagenase-3 expression is associated with advanced local invasion in human squamous cell carcinomas of the larynx. J. Pathol., 186: 144-150, 1998.
22. Chen, L. L., Narayanan, R., Hibbs, M. S., Benn, P. A., Clawson, M. L., Lu. G., Rhim, J. S., Greenberg, B., and Mendelsohn, J. Altered epidermal growth factor signal transduction in activated Ha-ras-transformed human keratinocytes. Biochem. Biophys. Res. Commun., 193: 167-174, 1993.
23. Rosenthal, E. L., Johnson, T. M., Allen, E. D., Apel, I. J., Punturieri, A., and Weiss, S. J. Role of the plasminogen activator and matrix metalloproteinase systems in epidermal growth factor-and scatter factor-stimulated invasion of carcinoma cells. Cancer Res., 58: 5221-5230, 1998.
24. McCawley, L. J., O'Brien, P., and Hudson, L. G. Epidermal growth factor (EGF)-and scatter factor/hepatocyle growth factor (SF/HGF)-mediated keratinocyte migration is coincident with induction of matrix metalloproteinase (MMP)-9. J. Cell Physiol., 176: 255-265, 1998.
25. Hyuga, S., Nishikawa, Y., Sakata, K., Tanaka, H., Yamagata, S., Sugita, K., Saga, S., Matsuyama, M., and Shimizu, S. Autocrine factor enhancing the secretion of M, 95,000 gelatinase (MMP-9) in serum-free medium conditioned with murine metastatic colon carcinoma cells. Cancer Res., 54: 3611-3616, 1994.
26. Kondapaka, S. B., Fridman, R., and Reddy, K. B. Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells. Int. J. Cancer, 70: 722-726, 1997.
27. Modjtahedi, H., Styles, J., Box, G., Eccles, S., Gusterson, B., and Dean, C. Antitumor activity of rat mAbs to the human receptor for EGF. In: A. A. Epenetos and N. R. Lemoine (eds.), Mutant Oncogenes: Targets for Therapy? pp. 35-47. London, United Kingdom: Chapman Hall, 1993.
28. Modjtahedi, H., Cohen, B. D., and Dean, C. Monoclonal antibodies against the EGF receptor show differential bindings of amphiregulin and EGF to the EGF receptor. Int. J. Oncol., 10: 339-347, 1997.
29. Styles, J. M., Harrison, S., Gusterson, B. A., and Dean, C. J. Rat monoclonal antibodies to the external domain of the product of the C-erbB-2 proto-oncogene. Int. J. Cancer, 45: 320-324, 1990.
30. O-charoenrat, P., Rhys-Evans, P., Modjtahedi, H., Court, W., Box, G., and Eccles, S. Overexpression of epidermal growth factor receptor in human head and neck squamous carcinoma cell lines correlates with matrix metalloproteinase-9 expression and in vitro invasion. Int. J. Cancer, in press, 2000.
31. Kleiner, D, E., and Stetler-Stcvenson, W. G. Quantitative zymography: detection of picogram quantities of gelatinases. Anal. Biochem., 218: 325-329, 1994.
32. Modjtahedi, H., Styles, J., and Dean, C. The growth response of human tumor cell lines expressing the EGF receptor to treatment with EGF and/or Mabs that block ligand binding. Int. J. Oncol., 3: 237-243, 1993.
33. Albini, A., Iwamoto, Y., Kleinman, H. K., Martin, G. R., Aaronson, S. A., Kozlowski, J. M., and McEwan, R. N. A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res., 47: 3239-3245, 1987.
34. Ramos-DeSimone, N., Moll, U. M., Quigley, J. P., and French, D. L. Inhibition of matrix metalloproteinase activation by a specific monoclonal antibody. Hybridoma, 12: 349-363, 1993.
35. Eccles, S. A., Modjtahedi, H., Box, G., Court, W., Sandle, J., and Dean, C. Significance of the c-erbB family of receptor tyrosine kinases in metastatic cancer and their potential as targets for immunotherapy. Invasion Metastasis, 14: 337-348, 1994.
36. Arrihas, J., Coodly, L., Vollmer, P., Kishimoto, T., Rose-John, S., and Massague, J. Diverse cell surface protein ectodomains are shed by a system sensitive to metalloproteinase inhibitors. J. Biol. Chem., 271: 11376-11382, 1996.
37. Lund-Johansen, M., Bjerkvig, R., Humphrey, P. A., Bigner, S. H., Bigner, D. D., and Laerum, O. D. Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro. Cancer Res., 50: 6039-6044, 1990.
38. Mizoguchi, H., Komiyama, S., Matsui, K., Hamanaka, R., Ono, M., Kiue, A., Kobayashi, M., Shimizu, N., Welgus, H. G., and Kuwano, M. The response to epidermal growth factor of human maxillary tumor cells in terms of tumor growth, invasion and expression of proteinase inhibitors. Int. J. Cancer, 49: 738-743, 1991.
39. Hoelting, T., Siperstein, A. E., Clark, O. H., and Duh, Q. Y. Epidermal growth factor enhances proliferation, migration, and invasion of follicular and papillary thyroid cancer in vitro and in vivo. J. Clin. Endocrinol. Metab., 79: 401-408, 1994.
40. Shima, I., Sasaguri, Y., Kusukawa, J., Nakano, R., Yamana, H., Fujita, H., Kakegawa, T., and Morimatsu, M. Production of matrix metalloproteinase 9 (92-kDa gelatinase) by human oesophageal squamous cell carcinoma in response to epidermal growth factor. Br. J. Cancer, 67: 721-727, 1993.
41. Huhtala, P., Tuuttila, A., Chow, L. T., Lohi, J., Keski-Oja, J., and Tryggvason, K. Complete structure of the human gene for 92-kDa type IV collagenase. Divergent regulation of expression for the 92-and 72-kilodalton enzyme genes in HT-1080 cells. J. Biol. Chem., 266: 16485-16490, 1991.
42. Brandt, B., Vogt, U., Schlotter, C. M., Jackisch, C., Werkmeister, R., Thomas, M., von Eiff, M., Bosse, U., Assmann, G., and Zanker, K. S. Prognostic relevance of aberrations in the erbB oncogenes from breast, ovarian, oral and lung cancers: double-differential polymerase chain reaction (ddPCR) for clinical diagnosis. Gene (Amst.), 159: 35-42, 1995.
43. Ibrahim, S. O., Vasstrand, E. N., Liavaag, P. G., Johannessen, A. C., and Lillehaug, J. R. Expression of c-erhB proto-oncogene family members in squamous cell carcinoma of the head and neck. Anticancer Res., 17: -4539-4546, 1997.
44. Funayama, T., Nakanishi, T., Takahashi, K., Taniguchi, S., Takigawa, M., and Matsumura, T. Overexpression of c-erbB-3 in various stages of human squamous cell carcinomas. Oncology (Basel), 55: 161-167, 1998.
45. Tzahar, E., Pinkas-Kramarski, R., Moyer, J. D., Klapper, L. N., Alroy, I., Levkowitz, G., Shelly, M., Henis, S., Eisenstein, M., Ratzkin, B. J., Sela, M., Andrews, G. C. and Yarden, Y. Bivalence of EGF-like ligands drives the ErbB signaling network. EMBO J., 16: 4938-4950, 1997.
46. Riese, D., II, Bermingham, Y., van Raaij, T., Buckley, S., Plowman, G., and Stern, D. Betacellulin activates the epidermal growth factor receptor and erbB-4 and induces cellular response patterns distinct from those stimulated by epidermal growth factor or neuregulin-β. Oncogene, 12: 345-353, 1996.