Taurine prevents cardiomyocyte death by inhibiting NADPH oxidase-mediated calpain activation

Free Radical Biology and Medicine

Volumn 46, Issue 1, 2009, Pages 51-61

  Li, Ying ^a,b   Arnold, J Malcolm O ^a,b   Pampillo, Macarena ^b,c   Babwah, Andy V ^b,c   Peng, Tianqing ^a,b  

^a LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c Children's Health Research Institute   (Canada)

Author keywords

Apoptosis; Calpain; Cardiomyocytes; Free radicals; NADPH oxidase; Taurine

Indexed keywords

BETA ALANINE; CALPAIN; CALPASTATIN; CASPASE 3; HYDROGEN PEROXIDE; NORADRENALIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TAURINE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; HEART MUSCLE CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; CALCIUM-BINDING PROTEINS; CALPAIN; CELL DEATH; CELLS, CULTURED; CYTOPROTECTION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEART VENTRICLES; HYDROGEN PEROXIDE; MALE; MICROSCOPY, CONFOCAL; MYOCYTES, CARDIAC; NADPH OXIDASE; NOREPINEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; TAURINE; TRANSGENES;

RATTUS;

EID: 57449119867     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2008.09.025     Document Type: Article

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