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Volumn 68, Issue 2, 2000, Pages 577-583

Neutrophils play a protective nonphagocytic role in systemic Mycobacterium tuberculosis infection of mice

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MONOCLONAL ANTIBODY; NITRIC OXIDE SYNTHASE;

EID: 0033958803     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.2.577-583.2000     Document Type: Article
Times cited : (229)

References (53)
  • 1
    • 0026684453 scopus 로고
    • Interferon-gamma (IFN-γ) and macrophage inflammatory proteins (MIP)-1 and -2 are involved in the regulation of the T cell-dependent chronic peritoneal neutrophilia of mice infected with mycobacteria
    • Appelberg, R. 1992. Interferon-gamma (IFN-γ) and macrophage inflammatory proteins (MIP)-1 and -2 are involved in the regulation of the T cell-dependent chronic peritoneal neutrophilia of mice infected with mycobacteria. Clin. Exp. Immunol. 89:269-273.
    • (1992) Clin. Exp. Immunol. , vol.89 , pp. 269-273
    • Appelberg, R.1
  • 2
    • 0026717745 scopus 로고
    • T cell regulation of the chronic peritoneal neutrophilia during mycobacterial infections
    • Appelberg, R. 1992. T cell regulation of the chronic peritoneal neutrophilia during mycobacterial infections. Clin. Exp. Immunol. 89:120-125.
    • (1992) Clin. Exp. Immunol. , vol.89 , pp. 120-125
    • Appelberg, R.1
  • 3
    • 0029121416 scopus 로고
    • Susceptibility of beige mice to Mycobacterium avium: Role of neutrophils
    • Appelberg, R., A. G. Castro, S. Gomes, J. Pedrosa, and M. T. Silva. 1995. Susceptibility of beige mice to Mycobacterium avium: role of neutrophils. Infect. Immun. 63:3381-3387.
    • (1995) Infect. Immun. , vol.63 , pp. 3381-3387
    • Appelberg, R.1    Castro, A.G.2    Gomes, S.3    Pedrosa, J.4    Silva, M.T.5
  • 4
    • 0028139111 scopus 로고
    • Neutrophils as effector cells of T-cell-mediated, acquired immunity in murine listeriosis
    • Appelberg, R., A. G. Castro, and M. T. Silva. 1994. Neutrophils as effector cells of T-cell-mediated, acquired immunity in murine listeriosis. Immunology 83:302-307.
    • (1994) Immunology , vol.83 , pp. 302-307
    • Appelberg, R.1    Castro, A.G.2    Silva, M.T.3
  • 5
    • 0026073001 scopus 로고
    • Host and bacterial factors control the Mycobacterium avium-induced chronic peritoneal granulocytosis in mice
    • Appelberg, R., J. M. Pedrosa, and M. T. Silva. 1991. Host and bacterial factors control the Mycobacterium avium-induced chronic peritoneal granulocytosis in mice. Clin. Exp. Immunol. 83:231-236.
    • (1991) Clin. Exp. Immunol. , vol.83 , pp. 231-236
    • Appelberg, R.1    Pedrosa, J.M.2    Silva, M.T.3
  • 6
    • 0029976839 scopus 로고    scopus 로고
    • Role of neutrophils in controlling early stages of a Chlamydia trachomatis infection
    • Barteneva, N., I. Theodor, E. M. Peterson, and L. M. de la Maza. 1996. Role of neutrophils in controlling early stages of a Chlamydia trachomatis infection. Infect. Immun. 64:4830-4833.
    • (1996) Infect. Immun. , vol.64 , pp. 4830-4833
    • Barteneva, N.1    Theodor, I.2    Peterson, E.M.3    De La Maza, L.M.4
  • 7
    • 0030890603 scopus 로고    scopus 로고
    • Mouse CD1-specific NK1 T cells: Development, specificity, and function
    • Bendelac, A., M. N. Rivera, S. H. Park, and J. H. Roark. 1997. Mouse CD1-specific NK1 T cells: development, specificity, and function. Annu. Rev. Immunol. 15:535-562.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 535-562
    • Bendelac, A.1    Rivera, M.N.2    Park, S.H.3    Roark, J.H.4
  • 8
    • 0033564304 scopus 로고    scopus 로고
    • Human polymorphonuclear leukocytes produce IL-12, TNF-alpha, and the chemokines macrophage-inflammatory protein-1 alpha and -1 beta in response to Toxoplasma gondii antigens
    • Bliss, S. K., A. J. Marshall, Y. Zhang, and E. Y. Denkers. 1999. Human polymorphonuclear leukocytes produce IL-12, TNF-alpha, and the chemokines macrophage-inflammatory protein-1 alpha and -1 beta in response to Toxoplasma gondii antigens. J. Immunol. 162:7369-7375.
    • (1999) J. Immunol. , vol.162 , pp. 7369-7375
    • Bliss, S.K.1    Marshall, A.J.2    Zhang, Y.3    Denkers, E.Y.4
  • 9
    • 0033567090 scopus 로고    scopus 로고
    • Murine neutrophil stimulation by Toxoplasma gondii antigen drives high level production of IFN-γ-independent IL-12
    • Bliss, S. K., Y. Zhang, and E. Y. Denkers. 1999. Murine neutrophil stimulation by Toxoplasma gondii antigen drives high level production of IFN-γ-independent IL-12. J. Immunol. 163:2081-2088.
    • (1999) J. Immunol. , vol.163 , pp. 2081-2088
    • Bliss, S.K.1    Zhang, Y.2    Denkers, E.Y.3
  • 10
    • 0023550258 scopus 로고
    • Capacity of human neutrophils to kill Mycobacterium tuberculosis
    • Brown, A. E. 1987. Capacity of human neutrophils to kill Mycobacterium tuberculosis. J. Infect. Dis. 156:985-989.
    • (1987) J. Infect. Dis. , vol.156 , pp. 985-989
    • Brown, A.E.1
  • 12
    • 0028894398 scopus 로고
    • The production of cytokines by polymorphonuclear neutrophils
    • Cassatella, M. A. 1995. The production of cytokines by polymorphonuclear neutrophils. Immunol. Today 16:21-26.
    • (1995) Immunol. Today , vol.16 , pp. 21-26
    • Cassatella, M.A.1
  • 14
    • 0029162723 scopus 로고
    • Endogenously produced IL-12 is required for the induction of protective T cells during Mycobacterium avium infections in mice
    • Castro, A. G., R. A. Silva, and R. Appelberg. 1995. Endogenously produced IL-12 is required for the induction of protective T cells during Mycobacterium avium infections in mice. J. Immunol. 155:2013-2019.
    • (1995) J. Immunol. , vol.155 , pp. 2013-2019
    • Castro, A.G.1    Silva, R.A.2    Appelberg, R.3
  • 15
    • 0031027463 scopus 로고    scopus 로고
    • Critical roles of neutrophils in host defense against experimental systemic infections of mice by Listeria monocytogenes, Salmonella typhimurium, and Yersinia enterocolitico
    • Conlan, J. W. 1997. Critical roles of neutrophils in host defense against experimental systemic infections of mice by Listeria monocytogenes, Salmonella typhimurium, and Yersinia enterocolitico. Infect. Immun. 65:630-635.
    • (1997) Infect. Immun. , vol.65 , pp. 630-635
    • Conlan, J.W.1
  • 16
    • 0028157125 scopus 로고
    • Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibody
    • Conlan, J. W., and R. J. North. 1994. Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibody. J. Exp. Med. 179:259-268.
    • (1994) J. Exp. Med. , vol.179 , pp. 259-268
    • Conlan, J.W.1    North, R.J.2
  • 17
    • 0031460924 scopus 로고    scopus 로고
    • Expression of memory immunity in the lung following re-exposure to Mycobacterium tuberculosis
    • Cooper, A. M., J. E. Callahan, M. Keen, J. T. Belisle, and I. M. Orme. 1997. Expression of memory immunity in the lung following re-exposure to Mycobacterium tuberculosis. Tuber. Lung Dis. 78:67-73.
    • (1997) Tuber. Lung Dis. , vol.78 , pp. 67-73
    • Cooper, A.M.1    Callahan, J.E.2    Keen, M.3    Belisle, J.T.4    Orme, I.M.5
  • 19
    • 0030790652 scopus 로고    scopus 로고
    • Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with Mycobacterium tuberculosis
    • Cooper, A. M., J. Magram, J. Ferrante, and I. M. Orme. 1997. Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with Mycobacterium tuberculosis. J. Exp. Med. 186:39-45.
    • (1997) J. Exp. Med. , vol.186 , pp. 39-45
    • Cooper, A.M.1    Magram, J.2    Ferrante, J.3    Orme, I.M.4
  • 20
    • 0028947010 scopus 로고
    • The role of interleukin-12 in acquired immunity to Mycobacterium tuberculosis infection
    • Cooper, A. M., A. D. Roberts, E. R. Rhoades, J. E. Calahan, D. M. Getzy, and I. M. Orme. 1995. The role of interleukin-12 in acquired immunity to Mycobacterium tuberculosis infection. Immunology 84:423-432.
    • (1995) Immunology , vol.84 , pp. 423-432
    • Cooper, A.M.1    Roberts, A.D.2    Rhoades, E.R.3    Calahan, J.E.4    Getzy, D.M.5    Orme, I.M.6
  • 21
    • 0028266104 scopus 로고
    • Administration of anti-granulocyte mAb RB6-8C5 impairs the resistance of mice to Listeria monocytogenes infection
    • Czuprynski, C. J., J. F. Brown, N. Maroushek, R. D. Wagner, and H. Steinberg. 1994. Administration of anti-granulocyte mAb RB6-8C5 impairs the resistance of mice to Listeria monocytogenes infection. J. Immunol. 156:1836-1846.
    • (1994) J. Immunol. , vol.156 , pp. 1836-1846
    • Czuprynski, C.J.1    Brown, J.F.2    Maroushek, N.3    Wagner, R.D.4    Steinberg, H.5
  • 22
    • 0028089787 scopus 로고
    • Administration of antigranulocyte monoclonal antibody RB6-8C5 prevents expression of acquired resistance to Listeria monocytogenes infection in previously immunized mice
    • Czuprynski, C. J., J. F. Brown, R. D. Wagner, and H. Steinberg. 1994. Administration of antigranulocyte monoclonal antibody RB6-8C5 prevents expression of acquired resistance to Listeria monocytogenes infection in previously immunized mice. Infect. Immun. 62:5161-5163.
    • (1994) Infect. Immun. , vol.62 , pp. 5161-5163
    • Czuprynski, C.J.1    Brown, J.F.2    Wagner, R.D.3    Steinberg, H.4
  • 23
    • 0027240219 scopus 로고
    • Interleukin 10 (IL-10) inhibits human lymphocyte Interferon gamma-production by suppressing natural killer cell stimulatory factor/ IL-12 synthesis in accessory cells
    • D'Andrea, A., M. Aste-Amezaga, N. M. Valiante, X. Ma, M. Kubin, and G. Trinchieri. 1993. Interleukin 10 (IL-10) inhibits human lymphocyte Interferon gamma-production by suppressing natural killer cell stimulatory factor/ IL-12 synthesis in accessory cells. J. Exp. Med. 178:1041-1048.
    • (1993) J. Exp. Med. , vol.178 , pp. 1041-1048
    • D'Andrea, A.1    Aste-Amezaga, M.2    Valiante, N.M.3    Ma, X.4    Kubin, M.5    Trinchieri, G.6
  • 24
    • 0025762359 scopus 로고
    • Human neutrophils, activated with cytokines or not, do not kill virulent Mycobacterium tuberculosis
    • Denis, M. 1991. Human neutrophils, activated with cytokines or not, do not kill virulent Mycobacterium tuberculosis. J. Infect. Dis. 163:919-920.
    • (1991) J. Infect. Dis. , vol.163 , pp. 919-920
    • Denis, M.1
  • 25
    • 0023733047 scopus 로고
    • Monocyte retention and migration in pulmonary inflammation. Requirement for neutrophils
    • Doherty, D. E., G. P. Downey, G. S. Worthen, C. Haslett, and P. M. Henson. 1988. Monocyte retention and migration in pulmonary inflammation. Requirement for neutrophils. Lab. Invest. 59:200-213.
    • (1988) Lab. Invest. , vol.59 , pp. 200-213
    • Doherty, D.E.1    Downey, G.P.2    Worthen, G.S.3    Haslett, C.4    Henson, P.M.5
  • 26
    • 0023231451 scopus 로고
    • Immunosuppression by activated human neutrophils. Dependence on the myeloperoxidase system
    • El-Hag, A., and R. A. Clark. 1987. Immunosuppression by activated human neutrophils. Dependence on the myeloperoxidase system. J. Immunol. 139: 2406-2413.
    • (1987) J. Immunol. , vol.139 , pp. 2406-2413
    • El-Hag, A.1    Clark, R.A.2
  • 27
    • 0027360333 scopus 로고
    • An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection
    • Flynn, J. L., J. Chan, K. J. Triebold, D. K. Dalton, T. A. Stewart, and B. R. Bloom. 1993. An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 178:2249-2254.
    • (1993) J. Exp. Med. , vol.178 , pp. 2249-2254
    • Flynn, J.L.1    Chan, J.2    Triebold, K.J.3    Dalton, D.K.4    Stewart, T.A.5    Bloom, B.R.6
  • 28
    • 0027264849 scopus 로고
    • Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts
    • Gazzinelli, R. T., S. Hieny, T. A. Wynn, S. Wolf, and A. Sher. 1993. Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts. Proc. Natl. Acad. Sci. USA 90:6115-6119.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6115-6119
    • Gazzinelli, R.T.1    Hieny, S.2    Wynn, T.A.3    Wolf, S.4    Sher, A.5
  • 29
    • 0018946065 scopus 로고
    • Expression of peroxidase-dependent iodonation by macrophages ingesting neutrophil debris
    • Heifets, L., K. Imai, and M. B. Goren. 1980. Expression of peroxidase-dependent iodonation by macrophages ingesting neutrophil debris. J. Reticuloendothel. Soc. 28:391-404.
    • (1980) J. Reticuloendothel. Soc. , vol.28 , pp. 391-404
    • Heifets, L.1    Imai, K.2    Goren, M.B.3
  • 30
    • 0027956689 scopus 로고
    • The role of phagocytic cells in resistance to disseminated candidiasis in granulocytopenic mice
    • Jensen, J., T. Warner, and E. Balish. 1994. The role of phagocytic cells in resistance to disseminated candidiasis in granulocytopenic mice. J. Infect. Dis. 170:900-905.
    • (1994) J. Infect. Dis. , vol.170 , pp. 900-905
    • Jensen, J.1    Warner, T.2    Balish, E.3
  • 31
    • 0025118297 scopus 로고
    • Killing of Mycobacterium tuberculosis by neutrophils: A nonoxidative process
    • Jones, G. S., H. J. Amirault, and B. R. Andersen. 1990. Killing of Mycobacterium tuberculosis by neutrophils: a nonoxidative process. J. Infect. Dis. 162:700-704.
    • (1990) J. Infect. Dis. , vol.162 , pp. 700-704
    • Jones, G.S.1    Amirault, H.J.2    Andersen, B.R.3
  • 32
    • 0029831666 scopus 로고    scopus 로고
    • High level IL-12 production by murine dendritic cells: Upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10
    • Koch, F., U. Stanzl, P. Jennewein, K. Janke, C. Heufler, E. Kampgen, N. Romani, and G. Schuler. 1996. High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10. J. Exp. Med. 184:741-746.
    • (1996) J. Exp. Med. , vol.184 , pp. 741-746
    • Koch, F.1    Stanzl, U.2    Jennewein, P.3    Janke, K.4    Heufler, C.5    Kampgen, E.6    Romani, N.7    Schuler, G.8
  • 33
    • 0024438603 scopus 로고
    • Uptake and utilization of human polymorphonuclear leucocyte granule myeloperoxidase
    • Leung, K. P., and M. B. Goren. 1989. Uptake and utilization of human polymorphonuclear leucocyte granule myeloperoxidase. Cell Tissue Res. 257:653-656.
    • (1989) Cell Tissue Res. , vol.257 , pp. 653-656
    • Leung, K.P.1    Goren, M.B.2
  • 34
    • 0021878455 scopus 로고
    • Lactoferrin effects on phagocytic cells function. I. Increased uptake and killing of an intracellular parasite by murine macrophages and human monocytes
    • Lima, M. F., and F. Kierszenbaum. 1985. Lactoferrin effects on phagocytic cells function. I. Increased uptake and killing of an intracellular parasite by murine macrophages and human monocytes. J. Immunol. 134:4176-4183.
    • (1985) J. Immunol. , vol.134 , pp. 4176-4183
    • Lima, M.F.1    Kierszenbaum, F.2
  • 35
    • 0029154538 scopus 로고
    • Exogenous myeloperoxidase enhances bacterial phagocytosis and intracellular killing by macrophages
    • Lincoln, J. A., D. L. Lefkowitz, A. Castro, S. S. Lefkowitz, N. Moguilevsky, and A. Bollen. 1995. Exogenous myeloperoxidase enhances bacterial phagocytosis and intracellular killing by macrophages. Infect. Immun. 63:3042-3047.
    • (1995) Infect. Immun. , vol.63 , pp. 3042-3047
    • Lincoln, J.A.1    Lefkowitz, D.L.2    Castro, A.3    Lefkowitz, S.S.4    Moguilevsky, N.5    Bollen, A.6
  • 37
    • 0025310338 scopus 로고
    • CAP37, a human neutrophil-derived chemotactic factor with monocyte specific activity
    • Pereira, H. A., W. M. Shafer, J. Pohl, L. E. Martin, and J. K. Spitznagel. 1990. CAP37, a human neutrophil-derived chemotactic factor with monocyte specific activity. J. Clin. Invest. 85:1468-1476.
    • (1990) J. Clin. Invest. , vol.85 , pp. 1468-1476
    • Pereira, H.A.1    Shafer, W.M.2    Pohl, J.3    Martin, L.E.4    Spitznagel, J.K.5
  • 38
    • 0033004698 scopus 로고    scopus 로고
    • Neutrophils from Mycobacterium avium-infected mice produce TNF-α, IL-12, and IL-1ß and have a putative role in early host response
    • Petrofsky, M., and L. E. Bermudez. 1999. Neutrophils from Mycobacterium avium-infected mice produce TNF-α, IL-12, and IL-1ß and have a putative role in early host response. Clin. Immunol. 91:354-358.
    • (1999) Clin. Immunol. , vol.91 , pp. 354-358
    • Petrofsky, M.1    Bermudez, L.E.2
  • 39
    • 0030777041 scopus 로고    scopus 로고
    • Chemokine secretion by human polymorphonuclear granulocytes after stimulation with Mycobacterium tuberculosis and lipoarabinomannan
    • Riedel, D. D., and S. H. Kaufmann. 1997. Chemokine secretion by human polymorphonuclear granulocytes after stimulation with Mycobacterium tuberculosis and lipoarabinomannan. Infect. Immun. 65:4620-4623.
    • (1997) Infect. Immun. , vol.65 , pp. 4620-4623
    • Riedel, D.D.1    Kaufmann, S.H.2
  • 40
    • 0027360893 scopus 로고
    • Neutrophils are involved in acute, nonspecific resistance to Listeria monocytogenes in mice
    • Rogers, H. W., and E. R. Unanue. 1993. Neutrophils are involved in acute, nonspecific resistance to Listeria monocytogenes in mice. Infect. Immun. 61:5090-5096.
    • (1993) Infect. Immun. , vol.61 , pp. 5090-5096
    • Rogers, H.W.1    Unanue, E.R.2
  • 43
    • 0029845257 scopus 로고    scopus 로고
    • Intranasal infection of beige mice with Mycobacterium avium complex: Role of neutrophils and natural killer cells
    • Saunders, B. M., and C. Cheers. 1996. Intranasal infection of beige mice with Mycobacterium avium complex: role of neutrophils and natural killer cells. Infect. Immun. 64:4236-4241.
    • (1996) Infect. Immun. , vol.64 , pp. 4236-4241
    • Saunders, B.M.1    Cheers, C.2
  • 44
    • 0029116788 scopus 로고
    • Endogenous interleukin-12 is involved in resistance of mice to Mycobacterium avium complex infection
    • Saunders, B. M., Y. Zhan, and C. Cheers. 1995. Endogenous interleukin-12 is involved in resistance of mice to Mycobacterium avium complex infection. Infect. Immun. 63:4011-4015.
    • (1995) Infect. Immun. , vol.63 , pp. 4011-4015
    • Saunders, B.M.1    Zhan, Y.2    Cheers, C.3
  • 45
    • 1842308284 scopus 로고    scopus 로고
    • Exacerbation of toxoplasmosis in neutrophil-depleted mice
    • Sayles, P. C., and L. L. Johnson. 1996. Exacerbation of toxoplasmosis in neutrophil-depleted mice. Nat. Immun. 15:249-258.
    • (1996) Nat. Immun. , vol.15 , pp. 249-258
    • Sayles, P.C.1    Johnson, L.L.2
  • 47
    • 0024375661 scopus 로고
    • Neutrophil-macrophage cooperation in the host defence against mycobacterial infections
    • Silva, M. T., M. N. T. Silva, and R. Appelberg. 1989. Neutrophil-macrophage cooperation in the host defence against mycobacterial infections. Microb. Pathog. 6:369-380.
    • (1989) Microb. Pathog. , vol.6 , pp. 369-380
    • Silva, M.T.1    Silva, M.N.T.2    Appelberg, R.3
  • 48
    • 0032533852 scopus 로고    scopus 로고
    • Evaluation of IL-12 in immunotherapy and vaccine design in experimental Mycobacterium avium infections
    • Silva, R. A., T. Pais, and R. Appelberg. 1998. Evaluation of IL-12 in immunotherapy and vaccine design in experimental Mycobacterium avium infections. J. Immunol. 161:5578-5585.
    • (1998) J. Immunol. , vol.161 , pp. 5578-5585
    • Silva, R.A.1    Pais, T.2    Appelberg, R.3
  • 49
    • 0028301218 scopus 로고
    • Neutrophils are critical for host defense against primary infection with the facultative intracellular bacterium Francisella tularensis in mice and participate in defense against reinfection
    • Sjostedt, A., J. W. Conlan, and R. J. North. 1994. Neutrophils are critical for host defense against primary infection with the facultative intracellular bacterium Francisella tularensis in mice and participate in defense against reinfection. Infect. Immun. 62:2779-2783.
    • (1994) Infect. Immun. , vol.62 , pp. 2779-2783
    • Sjostedt, A.1    Conlan, J.W.2    North, R.J.3
  • 50
    • 0024797674 scopus 로고
    • Monocyte-chemotactic activity of defensins from human neutrophils
    • Territo, M. C., T. Ganz, M. E. Selsted, and R. Lehrer. 1989. Monocyte-chemotactic activity of defensins from human neutrophils. J. Clin. Invest. 84:2017-2020.
    • (1989) J. Clin. Invest. , vol.84 , pp. 2017-2020
    • Territo, M.C.1    Ganz, T.2    Selsted, M.E.3    Lehrer, R.4
  • 51
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri, G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251-276.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 52
    • 0029973242 scopus 로고    scopus 로고
    • Immunoregulation by interleukin-12
    • Trinchieri, G., and F. Gerosa. 1996. Immunoregulation by interleukin-12. J. Leukoc. Biol. 59:505-511.
    • (1996) J. Leukoc. Biol. , vol.59 , pp. 505-511
    • Trinchieri, G.1    Gerosa, F.2
  • 53
    • 0027260963 scopus 로고
    • Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni
    • Wynn, T. A., I. Eltoum, A. W. Cheever, F. A. Lewis, W. C. Gause, and A. Sher. 1993. Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. J. Immunol. 151:1430-1440.
    • (1993) J. Immunol. , vol.151 , pp. 1430-1440
    • Wynn, T.A.1    Eltoum, I.2    Cheever, A.W.3    Lewis, F.A.4    Gause, W.C.5    Sher, A.6


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