메뉴 건너뛰기




Volumn 138, Issue 6, 2012, Pages 770-780

Molecular pathology of breast cancer: What a pathologist needs to know

Author keywords

Breast; HER2 FISH testing; Molecular diagnostics; Oncotype DX

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2;

EID: 84869213708     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCPIV9IQ1MRQMOO     Document Type: Review
Times cited : (83)

References (125)
  • 2
    • 69049088222 scopus 로고    scopus 로고
    • Tumor size is an unreliable predictor of prognosis in basal-like breast cancers and does not correlate closely with lymph node status
    • Foulkes WD, Grainge MJ, Rakha EA, et al. Tumor size is an unreliable predictor of prognosis in basal-like breast cancers and does not correlate closely with lymph node status. Breast Cancer Res Treat. 2009;117:199-204.
    • (2009) Breast Cancer Res Treat , vol.117 , pp. 199-204
    • Foulkes, W.D.1    Grainge, M.J.2    Rakha, E.A.3
  • 3
    • 81555216077 scopus 로고    scopus 로고
    • Gene expression profiling in breast cancer: Classification, prognostication, and prediction
    • Reis-Filho JS, Pusztai L. Gene expression profiling in breast cancer: classification, prognostication, and prediction. Lancet. 2011;378:1812-1823.
    • (2011) Lancet , vol.378 , pp. 1812-1823
    • Reis-Filho, J.S.1    Pusztai, L.2
  • 4
    • 33646874546 scopus 로고    scopus 로고
    • The molecular portraits of breast tumors are conserved across microarray platforms
    • Hu Z, Fan C, Oh DS, et al. The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genomics. 2006;7:96.
    • (2006) BMC Genomics , vol.7 , pp. 96
    • Hu, Z.1    Fan, C.2    Oh, D.S.3
  • 7
    • 73949136029 scopus 로고    scopus 로고
    • The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: A retrospective of the last decade
    • Weigelt B, Baehner FL, Reis-Filho JS. The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade. J Pathol. 2010;220:263-280.
    • (2010) J Pathol , vol.220 , pp. 263-280
    • Weigelt, B.1    Baehner, F.L.2    Reis-Filho, J.S.3
  • 8
    • 75649149550 scopus 로고    scopus 로고
    • Histological and molecular types of breast cancer: Is there a unifying taxonomy?
    • Weigelt B, Reis-Filho JS. Histological and molecular types of breast cancer: is there a unifying taxonomy? Nat Rev Clin Oncol. 2009;6:718-730.
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 718-730
    • Weigelt, B.1    Reis-Filho, J.S.2
  • 9
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM. Molecular portraits of human breast tumours. Nature. 2000;406:747-752.
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1
  • 12
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • The Cancer Genome Atlas Network
    • The Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature. 2012;490:61-70.
    • (2012) Nature , vol.490 , pp. 61-70
  • 13
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van't Veer LJ. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 2002;415:530-536.
    • (2002) Nature , vol.415 , pp. 530-536
    • Van't Veer, L.J.1
  • 15
    • 69749116768 scopus 로고    scopus 로고
    • Molecular classification of breast carcinomas by immunohistochemical analysis: Are we ready?
    • Tang P, Skinner KA, Hicks DG. Molecular classification of breast carcinomas by immunohistochemical analysis: are we ready? Diagn Mol Pathol. 2009;18:125-132.
    • (2009) Diagn Mol Pathol , vol.18 , pp. 125-132
    • Tang, P.1    Skinner, K.A.2    Hicks, D.G.3
  • 16
    • 66849140730 scopus 로고    scopus 로고
    • Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer
    • Cheang MC, Chia SK, Voduc D, et al. Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. J Natl Cancer Inst. 2009;101:736-750.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 736-750
    • Cheang, M.C.1    Chia, S.K.2    Voduc, D.3
  • 17
    • 51349088017 scopus 로고    scopus 로고
    • Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes
    • Desmedt C, Haibe-Kains B, Wirapati P, et al. Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes. Clin Cancer Res. 2008;14:5158-5165.
    • (2008) Clin Cancer Res , vol.14 , pp. 5158-5165
    • Desmedt, C.1    Haibe-Kains, B.2    Wirapati, P.3
  • 19
    • 58149330982 scopus 로고    scopus 로고
    • Meta-analysis of gene expression profiles in breast cancer: Toward a unified understanding of breast cancer subtyping and prognosis signatures
    • Wirapati P, Sotiriou C, Kunkel S, et al. Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures. Breast Cancer Res. 2008;10:R65.
    • (2008) Breast Cancer Res , vol.10
    • Wirapati, P.1    Sotiriou, C.2    Kunkel, S.3
  • 22
    • 33745660509 scopus 로고    scopus 로고
    • Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast
    • DOI 10.1111/j.1365-2559.2006.02453.x
    • Fulford LG, Easton DF, Reis-Filho JS, et al. Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast. Histopathology. 2006;49:22-34. (Pubitemid 43972917)
    • (2006) Histopathology , vol.49 , Issue.1 , pp. 22-34
    • Fulford, L.G.1    Easton, D.F.2    Reis-Filho, J.S.3    Sofronis, A.4    Gillett, C.E.5    Lakhani, S.R.6    Hanby, A.7
  • 27
    • 65249104546 scopus 로고    scopus 로고
    • Triple-negative breast cancer: Distinguishing between basal and nonbasal subtypes
    • Rakha EA, Elsheikh SE, Aleskandarany MA, et al. Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes. Clin Cancer Res. 2009;15:2302-2310.
    • (2009) Clin Cancer Res , vol.15 , pp. 2302-2310
    • Rakha, E.A.1    Elsheikh, S.E.2    Aleskandarany, M.A.3
  • 28
    • 79551649114 scopus 로고    scopus 로고
    • Basal-like and triple-negative breast cancers: A critical review with an emphasis on the implications for pathologists and oncologists
    • Badve S, Dabbs DJ, Schnitt SJ, et al. Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists. Mod Pathol. 2011;24:157-167.
    • (2011) Mod Pathol , vol.24 , pp. 157-167
    • Badve, S.1    Dabbs, D.J.2    Schnitt, S.J.3
  • 31
    • 34547860028 scopus 로고    scopus 로고
    • Differences in breast carcinoma characteristics in newly diagnosed African-American and Caucasian patients: A single-institution compilation compared with the national cancer institute's surveillance, epidemiology, and end results database
    • DOI 10.1002/cncr.22836
    • Morris GJ, Naidu S, Topham AK, et al. Differences in breast carcinoma characteristics in newly diagnosed African-American and Caucasian patients: a single-institution compilation compared with the National Cancer Institute's Surveillance, Epidemiology, and End Results database. Cancer. 2007;110:876-884. (Pubitemid 47257667)
    • (2007) Cancer , vol.110 , Issue.4 , pp. 876-884
    • Morris, G.J.1    Naidu, S.2    Topham, A.K.3    Guiles, F.4    Xu, Y.5    McCue, P.6    Schwartz, G.F.7    Park, P.K.8    Rosenberg, A.L.9    Brill, K.10    Mitchell, E.P.11
  • 33
    • 78650026917 scopus 로고    scopus 로고
    • Genomic signature of BRCA1 deficiency in sporadic basal-like breast tumors
    • Joosse SA, Brandwijk KI, Mulder L, et al. Genomic signature of BRCA1 deficiency in sporadic basal-like breast tumors. Genes Chromosomes Cancer. 2011;50:71-81.
    • (2011) Genes Chromosomes Cancer , vol.50 , pp. 71-81
    • Joosse, S.A.1    Brandwijk, K.I.2    Mulder, L.3
  • 34
    • 33749022506 scopus 로고    scopus 로고
    • Basal-like breast cancer and the BRCA1 phenotype
    • DOI 10.1038/sj.onc.1209876, PII 1209876
    • Turner NC, Reis-Filho JS. Basal-like breast cancer and the BRCA1 phenotype. Oncogene. 2006;25:5846-5853. (Pubitemid 44453440)
    • (2006) Oncogene , vol.25 , Issue.43 , pp. 5846-5853
    • Turner, N.C.1    Reis-Filho, J.S.2
  • 36
    • 67649540912 scopus 로고    scopus 로고
    • Basal cytokeratin and epidermal growth factor receptor expression are not predictive of BRCA1 mutation status in women with triple-negative breast cancers
    • Collins LC, Martyniak A, Kandel MJ, et al. Basal cytokeratin and epidermal growth factor receptor expression are not predictive of BRCA1 mutation status in women with triple-negative breast cancers. Am J Surg Pathol. 2009;33:1093-1097.
    • (2009) Am J Surg Pathol , vol.33 , pp. 1093-1097
    • Collins, L.C.1    Martyniak, A.2    Kandel, M.J.3
  • 38
    • 84865100704 scopus 로고    scopus 로고
    • A 50-gene intrinsic subtype classifier for prognosis and prediction of benefit from adjuvant tamoxifen
    • Chia SK, Bramwell VH, Tu D, et al. A 50-gene intrinsic subtype classifier for prognosis and prediction of benefit from adjuvant tamoxifen. Clin Cancer Res. 2012;18:4465-4472.
    • (2012) Clin Cancer Res , vol.18 , pp. 4465-4472
    • Chia, S.K.1    Bramwell, V.H.2    Tu, D.3
  • 39
    • 78049453780 scopus 로고    scopus 로고
    • A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptor-positive breast cancer
    • Nielsen TO, Parker JS, Leung S, et al. A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptor-positive breast cancer. Clin Cancer Res. 2010;16:5222-5232.
    • (2010) Clin Cancer Res , vol.16 , pp. 5222-5232
    • Nielsen, T.O.1    Parker, J.S.2    Leung, S.3
  • 40
    • 84868135433 scopus 로고    scopus 로고
    • Comparison of molecular subtyping with BluePrint, MammaPrint, and TargetPrint to local clinical subtyping in breast cancer patients
    • Nguyen B, Cusumano PG, Deck K, et al. Comparison of molecular subtyping with BluePrint, MammaPrint, and TargetPrint to local clinical subtyping in breast cancer patients. Ann Surg Oncol. 2012;19:3257-3263.
    • (2012) Ann Surg Oncol , vol.19 , pp. 3257-3263
    • Nguyen, B.1    Cusumano, P.G.2    Deck, K.3
  • 41
    • 33748578365 scopus 로고    scopus 로고
    • Molecular classification of breast cancer: Limitations and potential
    • DOI 10.1634/theoncologist.11-8-868
    • Pusztai L, Mazouni C, Anderson K, et al. Molecular classification of breast cancer: limitations and potential. Oncologist. 2006;11:868-877. (Pubitemid 44373759)
    • (2006) Oncologist , vol.11 , Issue.8 , pp. 868-877
    • Pusztai, L.1    Mazouni, C.2    Anderson, K.3    Wu, Y.4    Symmans, W.F.5
  • 42
    • 77950308839 scopus 로고    scopus 로고
    • Breast cancer molecular profiling with single sample predictors: A retrospective analysis
    • Weigelt B, Mackay A, A'Hern R, et al. Breast cancer molecular profiling with single sample predictors: a retrospective analysis. Lancet Oncol. 2010;11:339-349.
    • (2010) Lancet Oncol , vol.11 , pp. 339-349
    • Weigelt, B.1    Mackay, A.2    A'Hern, R.3
  • 43
    • 33845438621 scopus 로고    scopus 로고
    • Are clusters found in one dataset present in another dataset?
    • DOI 10.1093/biostatistics/kxj029
    • Kapp AV, Tibshirani R. Are clusters found in one dataset present in another dataset? Biostatistics. 2007;8:9-31. (Pubitemid 44906101)
    • (2007) Biostatistics , vol.8 , Issue.1 , pp. 9-31
    • Kapp, A.V.1    Tibshirani, R.2
  • 45
    • 79955391807 scopus 로고    scopus 로고
    • Microarray-based class discovery for molecular classification of breast cancer: Analysis of interobserver agreement
    • Mackay A, Weigelt B, Grigoriadis A, et al. Microarray-based class discovery for molecular classification of breast cancer: analysis of interobserver agreement. J Natl Cancer Inst. 2011;103:662-673.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 662-673
    • Mackay, A.1    Weigelt, B.2    Grigoriadis, A.3
  • 47
    • 79959654839 scopus 로고    scopus 로고
    • Systematic bias in genomic classification due to contaminating non-neoplastic tissue in breast tumor samples
    • Elloumi F, Hu Z, Li Y, et al. Systematic bias in genomic classification due to contaminating non-neoplastic tissue in breast tumor samples. BMC Medical Genomics. 2011;4:54.
    • (2011) BMC Medical Genomics , vol.4 , pp. 54
    • Elloumi, F.1    Hu, Z.2    Li, Y.3
  • 48
    • 33745445353 scopus 로고    scopus 로고
    • The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis
    • Cleator SJ, Powles TJ, Dexter T, et al. The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis. Breast Cancer Res. 2006;8:R32.
    • (2006) Breast Cancer Res , vol.8
    • Cleator, S.J.1    Powles, T.J.2    Dexter, T.3
  • 49
    • 65249138229 scopus 로고    scopus 로고
    • Tiling path genomic profiling of grade 3 invasive ductal breast cancers
    • Natrajan R, Lambros MB, Rodriguez-Pinilla SM, et al. Tiling path genomic profiling of grade 3 invasive ductal breast cancers. Clin Cancer Res. 2009;15:2711-2722.
    • (2009) Clin Cancer Res , vol.15 , pp. 2711-2722
    • Natrajan, R.1    Lambros, M.B.2    Rodriguez-Pinilla, S.M.3
  • 50
    • 77953123909 scopus 로고    scopus 로고
    • An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers
    • Natrajan R, Weigelt B, Mackay A, et al. An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers. Breast Cancer Res Treat. 2010;121:575-589.
    • (2010) Breast Cancer Res Treat , vol.121 , pp. 575-589
    • Natrajan, R.1    Weigelt, B.2    Mackay, A.3
  • 51
    • 78650028237 scopus 로고    scopus 로고
    • The molecular pathology of breast cancer progression
    • Bombonati A, Sgroi DC. The molecular pathology of breast cancer progression. J Pathol. 2011;223:307-317.
    • (2011) J Pathol , vol.223 , pp. 307-317
    • Bombonati, A.1    Sgroi, D.C.2
  • 52
    • 59449094654 scopus 로고    scopus 로고
    • Molecular characterization of breast cancer with high-resolution oligonucleotide comparative genomic hybridization array
    • Andre F, Job B, Dessen P, et al. Molecular characterization of breast cancer with high-resolution oligonucleotide comparative genomic hybridization array. Clin Cancer Res. 2009;15:441-451.
    • (2009) Clin Cancer Res , vol.15 , pp. 441-451
    • Andre, F.1    Job, B.2    Dessen, P.3
  • 53
    • 39749108733 scopus 로고    scopus 로고
    • High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer
    • Chin SF, Teschendorff AE, Marioni JC, et al. High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer. Genome Biol. 2007;8:R215.
    • (2007) Genome Biol , vol.8
    • Chin, S.F.1    Teschendorff, A.E.2    Marioni, J.C.3
  • 54
    • 78149477701 scopus 로고    scopus 로고
    • Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics
    • Jonsson G, Staaf J, Vallon-Christersson J, et al. Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics. Breast Cancer Res. 2010;12:R42.
    • (2010) Breast Cancer Res , vol.12
    • Jonsson, G.1    Staaf, J.2    Vallon-Christersson, J.3
  • 55
    • 77955837344 scopus 로고    scopus 로고
    • Breast cancer precursors revisited: Molecular features and progression pathways
    • Lopez-Garcia MA, Geyer FC, Lacroix-Triki M, et al. Breast cancer precursors revisited: molecular features and progression pathways. Histopathology. 2010;57:171-192.
    • (2010) Histopathology , vol.57 , pp. 171-192
    • Lopez-Garcia, M.A.1    Geyer, F.C.2    Lacroix-Triki, M.3
  • 56
    • 0032847233 scopus 로고    scopus 로고
    • Atypical cystic lobules: An early stage in the formation of low-grade ductal carcinoma in situ
    • DOI 10.1007/s004280050419
    • Oyama T, Maluf H, Koerner F. Atypical cystic lobules: an early stage in the formation of low-grade ductal carcinoma in situ. Virchows Arch. 1999;435:413-421. (Pubitemid 29472200)
    • (1999) Virchows Archiv , vol.435 , Issue.4 , pp. 413-421
    • Oyama, T.1    Maluf, H.2    Koerner, F.3
  • 57
    • 0030658021 scopus 로고    scopus 로고
    • Genetic alterations in lobular breast cancer by comparative genomic hybridization
    • Nishizaki T, Chew K, Chu L, et al. Genetic alterations in lobular breast cancer by comparative genomic hybridization. Int J Cancer. 1997;74:513.
    • (1997) Int J Cancer , vol.74 , pp. 513
    • Nishizaki, T.1    Chew, K.2    Chu, L.3
  • 58
    • 73649136867 scopus 로고    scopus 로고
    • The molecular underpinning of lobular histological growth pattern: A genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- And molecular subtype-matched invasive ductal carcinomas of no special type
    • Weigelt B, Kreike B, Geyer FC, et al. The molecular underpinning of lobular histological growth pattern: a genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- and molecular subtype-matched invasive ductal carcinomas of no special type. J Pathol. 2010;220:45-57.
    • (2010) J Pathol , vol.220 , pp. 45-57
    • Weigelt, B.1    Kreike, B.2    Geyer, F.C.3
  • 59
    • 13644259990 scopus 로고    scopus 로고
    • Molecular evolution of breast cancer
    • Simpson PT, Reis-Filho JS, Gale T, et al. Molecular evolution of breast cancer. J Pathol. 2005;205:248-254.
    • (2005) J Pathol , vol.205 , pp. 248-254
    • Simpson, P.T.1    Reis-Filho, J.S.2    Gale, T.3
  • 60
    • 0043155851 scopus 로고    scopus 로고
    • The diagnosis and management of pre-invasive breast disease: Genetic alterations in pre-invasive lesions
    • Reis-Filho JS, Lakhani SR. The diagnosis and management of pre-invasive breast disease: genetic alterations in pre-invasive lesions. Breast Cancer Res. 2003;5:313-319.
    • (2003) Breast Cancer Res , vol.5 , pp. 313-319
    • Reis-Filho, J.S.1    Lakhani, S.R.2
  • 62
  • 63
    • 77956218241 scopus 로고    scopus 로고
    • BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
    • Molyneux G, Geyer FC, Magnay FA, et al. BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. Cell Stem Cell. 2010;7:403-417.
    • (2010) Cell Stem Cell , vol.7 , pp. 403-417
    • Molyneux, G.1    Geyer, F.C.2    Magnay, F.A.3
  • 64
    • 33646157497 scopus 로고    scopus 로고
    • Ductal carcinoma in situ with basal-like phenotype: A possible precursor to invasive basal-like breast cancer
    • Bryan BB, Schnitt SJ, Collins LC. Ductal carcinoma in situ with basal-like phenotype: a possible precursor to invasive basal-like breast cancer. Mod Pathol. 2006;19:617-621.
    • (2006) Mod Pathol , vol.19 , pp. 617-621
    • Bryan, B.B.1    Schnitt, S.J.2    Collins, L.C.3
  • 65
    • 33847663351 scopus 로고    scopus 로고
    • P-cadherin and cytokeratin 5: Useful adjunct markers to distinguish basal-like ductal carcinomas in situ
    • DOI 10.1007/s00428-006-0334-y
    • Paredes J, Lopes N, Milanezi F, et al. P-cadherin and cytokeratin 5: useful adjunct markers to distinguish basal-like ductal carcinomas in situ. Virchows Arch. 2007;450:73-80. (Pubitemid 46360747)
    • (2007) Virchows Archiv , vol.450 , Issue.1 , pp. 73-80
    • Paredes, J.1    Lopes, N.2    Milanezi, F.3    Schmitt, F.C.4
  • 66
    • 57749118336 scopus 로고    scopus 로고
    • Comparison of molecular phenotypes of ductal carcinoma in situ and invasive breast cancer
    • Tamimi RM, Baer HJ, Marotti J, et al. Comparison of molecular phenotypes of ductal carcinoma in situ and invasive breast cancer. Breast Cancer Res. 2008;10:R67.
    • (2008) Breast Cancer Res , vol.10
    • Tamimi, R.M.1    Baer, H.J.2    Marotti, J.3
  • 68
    • 33750321934 scopus 로고    scopus 로고
    • Basal phenotype of ductal carcinoma in situ: Recognition and immunohistologic profile
    • DOI 10.1038/modpathol.3800678, PII 3800678
    • Dabbs DJ, Chivukula M, Carter G, et al. Basal phenotype of ductal carcinoma in situ: recognition and immunohistologic profile. Mod Pathol. 2006;19:1506-1511. (Pubitemid 44624171)
    • (2006) Modern Pathology , vol.19 , Issue.11 , pp. 1506-1511
    • Dabbs, D.J.1    Chivukula, M.2    Carter, G.3    Bhargava, R.4
  • 69
    • 38049051926 scopus 로고    scopus 로고
    • Immunohistochemical categorisation of ductal carcinoma in situ of the breast
    • Meijnen P, Peterse JL, Antonini N, et al. Immunohistochemical categorisation of ductal carcinoma in situ of the breast. Br J Cancer. 2008;98:137-142.
    • (2008) Br J Cancer , vol.98 , pp. 137-142
    • Meijnen, P.1    Peterse, J.L.2    Antonini, N.3
  • 70
    • 33751353068 scopus 로고    scopus 로고
    • Classification of ductal carcinoma in situ by gene expression profiling
    • Hannemann J, Velds A, Halfwerk JB, et al. Classification of ductal carcinoma in situ by gene expression profiling. Breast Cancer Res. 2006;8:R61.
    • (2006) Breast Cancer Res , vol.8
    • Hannemann, J.1    Velds, A.2    Halfwerk, J.B.3
  • 71
    • 84861550476 scopus 로고    scopus 로고
    • The life history of 21 breast cancers
    • Nik-Zainal S, Van Loo P, Wedge DC, et al. The life history of 21 breast cancers. Cell. 2012;149:994-1007.
    • (2012) Cell , vol.149 , pp. 994-1007
    • Nik-Zainal, S.1    Van Loo, P.2    Wedge, D.C.3
  • 72
    • 77949809850 scopus 로고    scopus 로고
    • Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas
    • Geyer FC, Weigelt B, Natrajan R, et al. Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas. J Pathol. 2010;220:562-573.
    • (2010) J Pathol , vol.220 , pp. 562-573
    • Geyer, F.C.1    Weigelt, B.2    Natrajan, R.3
  • 73
    • 77951139631 scopus 로고    scopus 로고
    • Genome remodelling in a basal-like breast cancer metastasis and xenograft
    • Ding L, Ellis MJ, Li S, et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature. 2010;464:999-1005.
    • (2010) Nature , vol.464 , pp. 999-1005
    • Ding, L.1    Ellis, M.J.2    Li, S.3
  • 74
    • 84862776906 scopus 로고    scopus 로고
    • Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
    • Ding L, Ley TJ, Larson DE, et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature. 2012;481:506-510.
    • (2012) Nature , vol.481 , pp. 506-510
    • Ding, L.1    Ley, T.J.2    Larson, D.E.3
  • 75
    • 84865998520 scopus 로고    scopus 로고
    • Implications of genetic heterogeneity in cancer
    • Schmitt MW, Prindle MJ, Loeb LA. Implications of genetic heterogeneity in cancer. Ann N Y Acad Sci. 2012;1267:110-116.
    • (2012) Ann N Y Acad Sci , vol.1267 , pp. 110-116
    • Schmitt, M.W.1    Prindle, M.J.2    Loeb, L.A.3
  • 76
    • 79953766940 scopus 로고    scopus 로고
    • Tumour evolution inferred by single-cell sequencing
    • Navin N, Kendall J, Troge J, et al. Tumour evolution inferred by single-cell sequencing. Nature 2011;472:90-94.
    • (2011) Nature , vol.472 , pp. 90-94
    • Navin, N.1    Kendall, J.2    Troge, J.3
  • 77
    • 70349969478 scopus 로고    scopus 로고
    • Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
    • Shah SP, Morin RD, Khattra J, et al. Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature. 2009;461:809-813.
    • (2009) Nature , vol.461 , pp. 809-813
    • Shah, S.P.1    Morin, R.D.2    Khattra, J.3
  • 78
    • 78049261497 scopus 로고    scopus 로고
    • Targeting chromosomal instability and tumour heterogeneity in HER2-positive breast cancer
    • Burrell RA, Juul N, Johnston SR, et al. Targeting chromosomal instability and tumour heterogeneity in HER2-positive breast cancer. J Cell Biochem. 2010;111:782-790.
    • (2010) J Cell Biochem , vol.111 , pp. 782-790
    • Burrell, R.A.1    Juul, N.2    Johnston, S.R.3
  • 79
    • 84856013431 scopus 로고    scopus 로고
    • Clonal evolution in cancer
    • Greaves M, Maley CC. Clonal evolution in cancer. Nature. 2012;481:306-313.
    • (2012) Nature , vol.481 , pp. 306-313
    • Greaves, M.1    Maley, C.C.2
  • 80
    • 84857568955 scopus 로고    scopus 로고
    • Prospective study evaluating the impact of tissue confirmation of metastatic disease in patients with breast cancer
    • Amir E, Miller N, Geddie W, et al. Prospective study evaluating the impact of tissue confirmation of metastatic disease in patients with breast cancer. J Clin Oncol. 2012;30:587-592.
    • (2012) J Clin Oncol , vol.30 , pp. 587-592
    • Amir, E.1    Miller, N.2    Geddie, W.3
  • 81
    • 84864085607 scopus 로고    scopus 로고
    • Clinically used breast cancer markers such as estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 are unstable throughout tumor progression
    • Lindstrom LS, Karlsson E, Wilking UM, et al. Clinically used breast cancer markers such as estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 are unstable throughout tumor progression. J Clin Oncol. 2012;30:2601-2608.
    • (2012) J Clin Oncol , vol.30 , pp. 2601-2608
    • Lindstrom, L.S.1    Karlsson, E.2    Wilking, U.M.3
  • 82
    • 60849085661 scopus 로고    scopus 로고
    • Version 3. Available at Accessed October 16, 2012
    • National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Breast Cancer Version 3.2012. Available at www.nccn.org/ professionals/physician-gls/recently-updated.asp. Accessed October 16, 2012.
    • (2012) NCCN Clinical Practice Guidelines in Oncology: Breast Cancer
  • 84
    • 34548794910 scopus 로고    scopus 로고
    • Breast carcinoma arising in microglandular adenosis: A review of the literature
    • Salarieh A, Sneige N. Breast carcinoma arising in microglandular adenosis: a review of the literature. Arch Pathol Lab Med. 2007;131:1397-1399. (Pubitemid 47427595)
    • (2007) Archives of Pathology and Laboratory Medicine , vol.131 , Issue.9 , pp. 1397-1399
    • Salarieh, A.1    Sneige, N.2
  • 85
    • 63849135922 scopus 로고    scopus 로고
    • Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma
    • Shin SJ, Simpson PT, Da Silva L, et al. Molecular evidence for progression of microglandular adenosis (MGA) to invasive carcinoma. Am J Surg Pathol. 2009;33:496-504.
    • (2009) Am J Surg Pathol , vol.33 , pp. 496-504
    • Shin, S.J.1    Simpson, P.T.2    Da Silva, L.3
  • 86
    • 82755177882 scopus 로고    scopus 로고
    • Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple-negative and basal-like breast cancers
    • Wetterskog D, Lopez-Garcia MA, Lambros MB, et al. Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple-negative and basal-like breast cancers. J Pathol. 2012;226:84-96.
    • (2012) J Pathol , vol.226 , pp. 84-96
    • Wetterskog, D.1    Lopez-Garcia, M.A.2    Lambros, M.B.3
  • 87
    • 84861527388 scopus 로고    scopus 로고
    • The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
    • Curtis C, Shah SP, Chin SF, et al. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature. 2012;486:346-352.
    • (2012) Nature , vol.486 , pp. 346-352
    • Curtis, C.1    Shah, S.P.2    Chin, S.F.3
  • 88
    • 84861576201 scopus 로고    scopus 로고
    • The landscape of cancer genes and mutational processes in breast cancer
    • Stephens PJ, Tarpey PS, Davies H, et al. The landscape of cancer genes and mutational processes in breast cancer. Nature. 2012;486:400-404.
    • (2012) Nature , vol.486 , pp. 400-404
    • Stephens, P.J.1    Tarpey, P.S.2    Davies, H.3
  • 89
    • 77953198056 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer
    • Hammond ME, Hayes DF, Dowsett M, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. Arch Pathol Lab Med. 2010;134:907-922.
    • (2010) Arch Pathol Lab Med , vol.134 , pp. 907-922
    • Hammond, M.E.1    Hayes, D.F.2    Dowsett, M.3
  • 91
    • 77955610459 scopus 로고    scopus 로고
    • Achieving 95% cross-methodological concordance in HER2 testing: Causes and implications of discordant cases
    • Grimm EE, Schmidt RA, Swanson PE, et al. Achieving 95% cross-methodological concordance in HER2 testing: causes and implications of discordant cases. Am J Clin Pathol. 2010;134:284-292.
    • (2010) Am J Clin Pathol , vol.134 , pp. 284-292
    • Grimm, E.E.1    Schmidt, R.A.2    Swanson, P.E.3
  • 92
    • 79957492068 scopus 로고    scopus 로고
    • Clinical notice for American Society of Clinical Oncology-College of American Pathologists guideline recommendations on ER/PgR and HER2 testing in breast cancer
    • Hammond ME, Hayes DF, Wolff AC. Clinical notice for American Society of Clinical Oncology-College of American Pathologists guideline recommendations on ER/PgR and HER2 testing in breast cancer. J Clin Oncol. 2011;29:e458.
    • (2011) J Clin Oncol , vol.29
    • Hammond, M.E.1    Hayes, D.F.2    Wolff, A.C.3
  • 93
    • 82655171622 scopus 로고    scopus 로고
    • Frequency of HER2 heterogeneity by fluorescence in situ hybridization according to CAP expert panel recommendations: Time for a new look at how to report heterogeneity
    • Allison KH, Dintzis SM, Schmidt RA. Frequency of HER2 heterogeneity by fluorescence in situ hybridization according to CAP expert panel recommendations: time for a new look at how to report heterogeneity. Am J Clin Pathol. 2011;136:864-871.
    • (2011) Am J Clin Pathol , vol.136 , pp. 864-871
    • Allison, K.H.1    Dintzis, S.M.2    Schmidt, R.A.3
  • 94
    • 84868207560 scopus 로고    scopus 로고
    • Genetic heterogeneity of HER2 in breast cancer: Impact on HER2 testing and its clinicopathologic significance
    • Yang YL, Fan Y, Lang RG, et al. Genetic heterogeneity of HER2 in breast cancer: impact on HER2 testing and its clinicopathologic significance. Breast Cancer Res Treat. 2012;134:1095-1102.
    • (2012) Breast Cancer Res Treat , vol.134 , pp. 1095-1102
    • Yang, Y.L.1    Fan, Y.2    Lang, R.G.3
  • 95
    • 84860459660 scopus 로고    scopus 로고
    • 'Genetic heterogeneity' in HER2/neu testing by fluorescence in situ hybridization: A study of 2,522 cases
    • Chang MC, Malowany JI, Mazurkiewicz J, et al. 'Genetic heterogeneity' in HER2/neu testing by fluorescence in situ hybridization: a study of 2,522 cases. Mod Pathol. 2012;25:683-688.
    • (2012) Mod Pathol , vol.25 , pp. 683-688
    • Chang, M.C.1    Malowany, J.I.2    Mazurkiewicz, J.3
  • 96
    • 81855170189 scopus 로고    scopus 로고
    • HER2 genetic heterogeneity in breast carcinoma
    • Ohlschlegel C, Zahel K, Kradolfer D, et al. HER2 genetic heterogeneity in breast carcinoma. J Clin Pathol. 2011;64:1112-1116.
    • (2011) J Clin Pathol , vol.64 , pp. 1112-1116
    • Ohlschlegel, C.1    Zahel, K.2    Kradolfer, D.3
  • 97
    • 84855567211 scopus 로고    scopus 로고
    • Intratumoral heterogeneity determines discordant results of diagnostic tests for human epidermal growth factor receptor (HER) 2 in gastric cancer specimens
    • Yang J, Luo H, Li Y, et al. Intratumoral heterogeneity determines discordant results of diagnostic tests for human epidermal growth factor receptor (HER) 2 in gastric cancer specimens. Cell Biochem Biophys. 2012;62:221-228.
    • (2012) Cell Biochem Biophys , vol.62 , pp. 221-228
    • Yang, J.1    Luo, H.2    Li, Y.3
  • 98
    • 84860336925 scopus 로고    scopus 로고
    • Genetic heterogeneity in HER2 testing may influence therapy eligibility
    • Bernasconi B, Chiaravalli AM, Finzi G, et al. Genetic heterogeneity in HER2 testing may influence therapy eligibility. Breast Cancer Res Treat. 2012;133:161-168.
    • (2012) Breast Cancer Res Treat , vol.133 , pp. 161-168
    • Bernasconi, B.1    Chiaravalli, A.M.2    Finzi, G.3
  • 99
    • 79961007548 scopus 로고    scopus 로고
    • Heterogeneous HER2 gene amplification: Impact on patient outcome and a clinically relevant definition
    • Bartlett AI, Starcyznski J, Robson T, et al. Heterogeneous HER2 gene amplification: impact on patient outcome and a clinically relevant definition. Am J Clin Pathol. 2011;136:266-274.
    • (2011) Am J Clin Pathol , vol.136 , pp. 266-274
    • Bartlett, A.I.1    Starcyznski, J.2    Robson, T.3
  • 100
    • 45749157664 scopus 로고    scopus 로고
    • Commercialized multigene predictors of clinical outcome for breast cancer
    • DOI 10.1634/theoncologist.2007-0248
    • Ross JS, Hatzis C, Symmans WF, et al. Commercialized multigene predictors of clinical outcome for breast cancer. Oncologist. 2008;13:477-493. (Pubitemid 351872866)
    • (2008) Oncologist , vol.13 , Issue.5 , pp. 477-493
    • Ross, J.S.1    Hatzis, C.2    Symmans, W.F.3    Pusztai, L.4    Hortobagyi, G.N.5
  • 101
    • 71249163835 scopus 로고    scopus 로고
    • Calibration and discriminatory accuracy of prognosis calculation for breast cancer with the online Adjuvant! program: A hospital-based retrospective cohort study
    • Mook S, Schmidt MK, Rutgers EJ, et al. Calibration and discriminatory accuracy of prognosis calculation for breast cancer with the online Adjuvant! program: a hospital-based retrospective cohort study. Lancet Oncol. 2009;10:1070-1076.
    • (2009) Lancet Oncol , vol.10 , pp. 1070-1076
    • Mook, S.1    Schmidt, M.K.2    Rutgers, E.J.3
  • 102
    • 73249140371 scopus 로고    scopus 로고
    • Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: A retrospective analysis of a randomised trial
    • Albain KS. Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor- positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial. Lancet Oncol. 2010;11:55-65.
    • (2010) Lancet Oncol , vol.11 , pp. 55-65
    • Albain, K.S.1
  • 104
    • 33744808550 scopus 로고    scopus 로고
    • A population-based study of tumor gene expression and risk of breast cancer death among lymph node-negative patients
    • Habel LA. A population-based study of tumor gene expression and risk of breast cancer death among lymph node-negative patients. Breast Cancer Res. 2006;8:R25.
    • (2006) Breast Cancer Res , vol.8
    • Habel, L.A.1
  • 106
    • 81155133281 scopus 로고    scopus 로고
    • Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the Genomic Health recurrence score in early breast cancer
    • Cuzick J, Dowsett M, Pineda S, et al. Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the Genomic Health recurrence score in early breast cancer. J Clin Oncol. 2011;29:4273-4278.
    • (2011) J Clin Oncol , vol.29 , pp. 4273-4278
    • Cuzick, J.1    Dowsett, M.2    Pineda, S.3
  • 108
    • 34249311296 scopus 로고    scopus 로고
    • Individualization of therapy using MammaPrint: From development to the MINDACT Trial
    • Mook S, Van't Veer LJ, Rutgers EJ, et al. Individualization of therapy using MammaPrint: from development to the MINDACT Trial. Cancer Genomics Proteomics. 2007;4:147-155.
    • (2007) Cancer Genomics Proteomics , vol.4 , pp. 147-155
    • Mook, S.1    Van'T Veer, L.J.2    Rutgers, E.J.3
  • 110
    • 33750895236 scopus 로고    scopus 로고
    • TAILORx: Trial Assigning Individualized Options for Treatment (Rx)
    • Sparano JA. TAILORx: Trial Assigning Individualized Options for Treatment (Rx). Clin Breast Cancer. 2006;7:347-350. (Pubitemid 44717771)
    • (2006) Clinical Breast Cancer , vol.7 , Issue.4 , pp. 347-350
    • Sparano, J.A.1
  • 111
    • 74849111553 scopus 로고    scopus 로고
    • The 70-gene signature as a response predictor for neoadjuvant chemotherapy in breast cancer
    • Straver ME. The 70-gene signature as a response predictor for neoadjuvant chemotherapy in breast cancer. Breast Cancer Res Treat. 2010;119:551-558.
    • (2010) Breast Cancer Res Treat , vol.119 , pp. 551-558
    • Straver, M.E.1
  • 112
    • 49649114805 scopus 로고    scopus 로고
    • Analysis of the MammaPrint breast cancer assay in a predominantly postmenopausal cohort
    • Wittner BS. Analysis of the MammaPrint breast cancer assay in a predominantly postmenopausal cohort. Clin Cancer Res. 2008;14:2988-2993.
    • (2008) Clin Cancer Res , vol.14 , pp. 2988-2993
    • Wittner, B.S.1
  • 113
    • 67649183386 scopus 로고    scopus 로고
    • The 70-gene prognosis-signature predicts disease outcome in breast cancer patients with 1-3 positive lymph nodes in an independent validation study
    • Mook S, Schmidt MK, Viale G, et al. The 70-gene prognosis-signature predicts disease outcome in breast cancer patients with 1-3 positive lymph nodes in an independent validation study. Breast Cancer Res Treat. 2009;116:295-302.
    • (2009) Breast Cancer Res Treat , vol.116 , pp. 295-302
    • Mook, S.1    Schmidt, M.K.2    Viale, G.3
  • 114
    • 77950862535 scopus 로고    scopus 로고
    • The 70-gene prognosis signature predicts early metastasis in breast cancer patients between 55 and 70 years of age
    • Mook S, Schmidt MK, Weigelt B, et al. The 70-gene prognosis signature predicts early metastasis in breast cancer patients between 55 and 70 years of age. Ann Oncol. 2010;21:717-722.
    • (2010) Ann Oncol , vol.21 , pp. 717-722
    • Mook, S.1    Schmidt, M.K.2    Weigelt, B.3
  • 115
    • 20444500954 scopus 로고    scopus 로고
    • Technology insight: Application of molecular techniques to formalin-fixed paraffin-embedded tissues from breast cancer
    • DOI 10.1038/ncponc0171
    • Paik S, Kim CY, Song YK, et al. Technology insight: application of molecular techniques to formalin-fixed paraffin-embedded tissues from breast cancer. Nat Clin Pract Oncol. 2005;2:246-254. (Pubitemid 40812455)
    • (2005) Nature Clinical Practice Oncology , vol.2 , Issue.5 , pp. 246-254
    • Paik, S.1    Kim, C.-Y.2    Song, Y.-K.3    Kim, W.-S.4
  • 116
    • 84856226700 scopus 로고    scopus 로고
    • Routine pathologic parameters can predict Oncotype DX recurrence scores in subsets of ER positive patients: Who does not always need testing?
    • Allison KH, Kandalaft PL, Sitlani CM, et al. Routine pathologic parameters can predict Oncotype DX recurrence scores in subsets of ER positive patients: who does not always need testing? Breast Cancer Res Treat. 2012;131:413-424.
    • (2012) Breast Cancer Res Treat , vol.131 , pp. 413-424
    • Allison, K.H.1    Kandalaft, P.L.2    Sitlani, C.M.3
  • 117
    • 84861455787 scopus 로고    scopus 로고
    • Assessment of the contribution of the IHC4+C score to decision making in clinical practice in early breast cancer
    • Barton S, Zabaglo L, A'Hern R, et al. Assessment of the contribution of the IHC4+C score to decision making in clinical practice in early breast cancer. Br J Cancer. 2012;106:1760-1765.
    • (2012) Br J Cancer , vol.106 , pp. 1760-1765
    • Barton, S.1    Zabaglo, L.2    A'Hern, R.3
  • 118
    • 84870656848 scopus 로고    scopus 로고
    • Comparison of prognostic values between combined immunohistochemical score of estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2, Ki-67 and the corresponding gene expression score in breast cancer
    • published online ahead of print August 24, 2012
    • Yamamoto-Ibusuki M, Yamamoto Y, Yamamoto S, et al. Comparison of prognostic values between combined immunohistochemical score of estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2, Ki-67 and the corresponding gene expression score in breast cancer [published online ahead of print August 24, 2012]. Mod Pathol.
    • Mod Pathol
    • Yamamoto-Ibusuki, M.1    Yamamoto, Y.2    Yamamoto, S.3
  • 120
    • 52549110816 scopus 로고    scopus 로고
    • Histopathologic variables predict Oncotype DX recurrence score
    • Flanagan MB, Dabbs DJ, Brufsky AM, et al. Histopathologic variables predict Oncotype DX recurrence score. Mod Pathol. 2008;21:1255-1261.
    • (2008) Mod Pathol , vol.21 , pp. 1255-1261
    • Flanagan, M.B.1    Dabbs, D.J.2    Brufsky, A.M.3
  • 121
    • 78449291165 scopus 로고    scopus 로고
    • Utility of oncotype DX risk estimates in clinically intermediate risk hormone receptor-positive, HER2-normal, grade II, lymph node-negative breast cancers
    • Kelly CM, Krishnamurthy S, Bianchini G, et al. Utility of oncotype DX risk estimates in clinically intermediate risk hormone receptor-positive, HER2-normal, grade II, lymph node-negative breast cancers. Cancer. 2010;116:5161-5167.
    • (2010) Cancer , vol.116 , pp. 5161-5167
    • Kelly, C.M.1    Krishnamurthy, S.2    Bianchini, G.3
  • 122
    • 68349160478 scopus 로고    scopus 로고
    • Complementary value of the Ki-67 proliferation index to the oncotype DX recurrence score
    • Gwin K, Pinto M, Tavassoli FA. Complementary value of the Ki-67 proliferation index to the oncotype DX recurrence score. Int J Surg Pathol. 2009;17:303-310.
    • (2009) Int J Surg Pathol , vol.17 , pp. 303-310
    • Gwin, K.1    Pinto, M.2    Tavassoli, F.A.3
  • 123
    • 0033571272 scopus 로고    scopus 로고
    • Analysis of chemical modification of RNA from formalin-fixed samples and optimization of molecular biology applications for such samples
    • DOI 10.1093/nar/27.22.4436
    • Masuda N, Ohnishi T, Kawamoto S, et al. Analysis of chemical modification of RNA from formalin-fixed samples and optimization of molecular biology applications for such samples. Nucleic Acids Res. 1999;27:4436-4443. (Pubitemid 29533185)
    • (1999) Nucleic Acids Research , vol.27 , Issue.22 , pp. 4436-4443
    • Masuda, N.1    Ohnishi, T.2    Kawamoto, S.3    Monden, M.4    Okubo, K.5
  • 124
    • 64849095162 scopus 로고    scopus 로고
    • Genetic heterogeneity in HER2 testing in breast cancer: Panel summary and guidelines
    • Vance GH, Barry TS, Bloom KJ, et al. Genetic heterogeneity in HER2 testing in breast cancer: panel summary and guidelines. Arch Pathol Lab Med. 2009;133:611-612.
    • (2009) Arch Pathol Lab Med , vol.133 , pp. 611-612
    • Vance, G.H.1    Barry, T.S.2    Bloom, K.J.3
  • 125
    • 84860595433 scopus 로고    scopus 로고
    • HER2 gene amplification in breast cancer: A rogues' gallery of challenging diagnostic cases: UKNEQAS interpretation guidelines and research recommendations
    • Starczynski J, Atkey N, Connelly Y, et al. HER2 gene amplification in breast cancer: a rogues' gallery of challenging diagnostic cases: UKNEQAS interpretation guidelines and research recommendations. Am J Clin Pathol. 2012;137:595-605.
    • (2012) Am J Clin Pathol , vol.137 , pp. 595-605
    • Starczynski, J.1    Atkey, N.2    Connelly, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.