Systematic Bias in genomic classification due to contaminating non-neoplastic tissue in breast tumor samples

BMC Medical Genomics

Volumn 4, Issue , 2011, Pages

  Elloumi, Fathi ^a   Hu, Zhiyuan ^a   Li, Yan ^a   Parker, Joel S ^a   Gulley, Margaret L ^a,b   Amos, Keith D ^a,b   Troester, Melissa A ^a,c  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c IL   (United States)

Author keywords

bias; biomarker validation; breast cancer; genomic assays; normal tissue

Indexed keywords

ADULT; ARTICLE; BREAST CANCER; CANCER CLASSIFICATION; CANCER RELAPSE; CANCER TISSUE; CONTAMINATION; CONTROLLED STUDY; DISEASE FREE SURVIVAL; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PREDICTION; PREDICTIVE VALUE; PRIORITY JOURNAL; PROCESS MODEL; QUALITY CONTROL; RECURRENCE RISK; RELIABILITY; SCORING SYSTEM; SENSITIVITY ANALYSIS; SYSTEMATIC ERROR; TISSUE CONTAMINATION; BREAST; BREAST TUMOR; CLASSIFICATION; COMPUTER SIMULATION; EPIDEMIOLOGY; FEMALE; GENETICS; GENOMICS; HUMAN GENOME; METHODOLOGY; MICROARRAY ANALYSIS; NEOPLASM; PATHOLOGY; REPRODUCIBILITY;

BIAS (EPIDEMIOLOGY); BREAST; BREAST NEOPLASMS; COMPUTER SIMULATION; FEMALE; GENOME, HUMAN; GENOMICS; HUMANS; MICROARRAY ANALYSIS; NEOPLASMS; REPRODUCIBILITY OF RESULTS;

EID: 79959654839     PISSN: None     EISSN: 17558794     Source Type: Journal    
DOI: 10.1186/1755-8794-4-54     Document Type: Article

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