On the Specificity of Heparin/Heparan Sulfate Binding to Proteins. Anion-Binding Sites on Antithrombin and Thrombin Are Fundamentally Different

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Mosier, Philip D ^a   Krishnasamy, Chandravel ^a   Kellogg, Glen E ^a   Desai, Umesh R ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANION; ANTITHROMBIN; ARGININE; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HEPARIN; LYSINE; PENTASACCHARIDE; SOLVENT; THROMBIN; WATER;

ARTICLE; BINDING SITE; CALCULATION; COMPUTER MODEL; COMPUTER PROGRAM; CRYSTAL STRUCTURE; EXPOSURE; MATHEMATICAL ANALYSIS; PREDICTION; PROTEIN BINDING; PROTEIN INTERACTION;

AMINO ACIDS; ANTITHROMBINS; BINDING SITES; HEPARIN; HEPARITIN SULFATE; MOLECULAR DOCKING SIMULATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS; SPECIES SPECIFICITY; THROMBIN; WATER;

EID: 84869073602     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048632     Document Type: Article

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