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Volumn 32, Issue 46, 2012, Pages 16181-16192

β-secretase cleavage of the fly amyloid precursor protein is required for glial survival

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; MESSENGER RNA; NEU DIFFERENTIATION FACTOR; VOLTAGE GATED SODIUM CHANNEL;

EID: 84869029962     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0228-12.2012     Document Type: Article
Times cited : (27)

References (44)
  • 2
    • 0000064419 scopus 로고
    • Behavioral mutants of Drosophila isolated by countercurrent distripution
    • CrossRef Medline
    • Benzer S (1967) Behavioral mutants of Drosophila isolated by countercurrent distripution. Proc Natl Acad Sci U S A 58:1112-1119. CrossRef Medline
    • (1967) Proc Natl Acad Sci U S A , vol.58 , pp. 1112-1119
    • Benzer, S.1
  • 3
    • 18244384190 scopus 로고    scopus 로고
    • Disruption of the MAP1B-related protein FUTSCH leads to changes in the neuronal cytoskeleton, axonal transport defects, and progressive neurodegeneration in Drosophila
    • CrossRef Medline
    • Bettencourt da Cruz A, Schwärzel M, Schulze S, Niyyati M, Heisenberg M, Kretzschmar D (2005) Disruption of the MAP1B-related protein FUTSCH leads to changes in the neuronal cytoskeleton, axonal transport defects, and progressive neurodegeneration in Drosophila. Mol Biol Cell 16:2433-2442.CrossRef Medline
    • (2005) Mol Biol Cell , vol.16 , pp. 2433-2442
    • da Bettencourt, C.A.1    Schwärzel, M.2    Schulze, S.3    Niyyati, M.4    Heisenberg, M.5    Kretzschmar, D.6
  • 4
    • 70349897797 scopus 로고    scopus 로고
    • CGB Technical Report 10. Bloomington, IN: The Center for Genomics and Bioinformatics
    • Bogart K, Andrews J (2006) Extraction of Total RNA from Drosophila. CGB Technical Report 10. Bloomington, IN: The Center for Genomics and Bioinformatics.
    • (2006) Extraction of Total RNA From Drosophila
    • Bogart, K.1    Andrews, J.2
  • 5
    • 0035112647 scopus 로고    scopus 로고
    • BACE1 is the major beta-secretase for generation of Abeta peptides by neurons
    • CrossRef Medline
    • Cai H, Wang Y, McCarthy D, Wen H, Borchelt DR, Price DL, Wong PC (2001) BACE1 is the major beta-secretase for generation of Abeta peptides by neurons. Nat Neurosci 4:233-234.CrossRef Medline
    • (2001) Nat Neurosci , vol.4 , pp. 233-234
    • Cai, H.1    Wang, Y.2    McCarthy, D.3    Wen, H.4    Borchelt, D.R.5    Price, D.L.6    Wong, P.C.7
  • 6
    • 58149503769 scopus 로고    scopus 로고
    • Neurotoxic effects induced by the Drosophila amyloid-beta peptide suggest a conserved toxic function
    • CrossRef Medline
    • Carmine-Simmen K, Proctor T, Tschäpe J, Poeck B, Triphan T, Strauss R, Kretzschmar D (2009) Neurotoxic effects induced by the Drosophila amyloid-beta peptide suggest a conserved toxic function. Neurobiol Dis 33:274-281.CrossRef Medline
    • (2009) Neurobiol Dis , vol.33 , pp. 274-281
    • Carmine-Simmen, K.1    Proctor, T.2    Tschäpe, J.3    Poeck, B.4    Triphan, T.5    Strauss, R.6    Kretzschmar, D.7
  • 9
    • 77950857749 scopus 로고    scopus 로고
    • The functional organisation of gliain the adult brain of Drosophila and other insects
    • CrossRef Medline
    • Edwards TN, Meinertzhagen IA (2010) The functional organisation of gliain the adult brain of Drosophila and other insects. Prog Neurobiol 90: 471-497.CrossRef Medline
    • (2010) Prog Neurobiol , vol.90 , pp. 471-497
    • Edwards, T.N.1    Meinertzhagen, I.A.2
  • 12
    • 33845236399 scopus 로고    scopus 로고
    • Bace1 modulates myelination in the central and peripheral nervous system
    • CrossRef Medline
    • Hu X, Hicks CW, He W, Wong P, Macklin WB, Trapp BD, Yan R (2006) Bace1 modulates myelination in the central and peripheral nervous system. Nat Neurosci 9:1520-1525.CrossRef Medline
    • (2006) Nat Neurosci , vol.9 , pp. 1520-1525
    • Hu, X.1    Hicks, C.W.2    He, W.3    Wong, P.4    Macklin, W.B.5    Trapp, B.D.6    Yan, R.7
  • 13
    • 77954394162 scopus 로고    scopus 로고
    • BACE1 deficiency causes altered neuronal activity and neurodegeneration
    • CrossRef Medline
    • Hu X, Zhou X, He W, Yang J, Xiong W, Wong P, Wilson CG, Yan R (2010) BACE1 deficiency causes altered neuronal activity and neurodegeneration. J Neurosci 30:8819-8829. CrossRef Medline
    • (2010) J Neurosci , vol.30 , pp. 8819-8829
    • Hu, X.1    Zhou, X.2    He, W.3    Yang, J.4    Xiong, W.5    Wong, P.6    Wilson, C.G.7    Yan, R.8
  • 14
    • 0033680949 scopus 로고    scopus 로고
    • Drosophila Futsch/22C10 is a MAP1B-like protein required for dendritic and axonal development
    • CrossRef Medline
    • Hummel T, Krukkert K, Roos J, Davis G, Klämbt C (2000) Drosophila Futsch/22C10 is a MAP1B-like protein required for dendritic and axonal development. Neuron 26:357-370.CrossRef Medline
    • (2000) Neuron , vol.26 , pp. 357-370
    • Hummel, T.1    Krukkert, K.2    Roos, J.3    Davis, G.4    Klämbt, C.5
  • 16
    • 79953129279 scopus 로고    scopus 로고
    • Reduced sodium channel Na(v)1.1 levels in BACE1-null mice
    • Medline
    • Kim DY, Gersbacher MT, Inquimbert P, Kovacs DM (2011) Reduced sodium channel Na(v)1.1 levels in BACE1-null mice. J Biol Chem 286: 8106-8116.Medline
    • (2011) J Biol Chem , vol.286 , pp. 8106-8116
    • Kim, D.Y.1    Gersbacher, M.T.2    Inquimbert, P.3    Kovacs, D.M.4
  • 17
    • 0036146742 scopus 로고    scopus 로고
    • Glia in development, function, and neurodegeneration of the adult insect brain
    • CrossRef Medline
    • Kretzschmar D, Pflugfelder GO (2002) Glia in development, function, and neurodegeneration of the adult insect brain. Brain Res Bull 57:121-131. CrossRef Medline
    • (2002) Brain Res Bull , vol.57 , pp. 121-131
    • Kretzschmar, D.1    Pflugfelder, G.O.2
  • 18
    • 0030864464 scopus 로고    scopus 로고
    • The swiss cheese mutant causes glial hyperwrapping and brain degeneration inDrosophila
    • Medline
    • Kretzschmar D, Hasan G, Sharma S, Heisenberg M, Benzer S (1997) The swiss cheese mutant causes glial hyperwrapping and brain degeneration inDrosophila. J Neurosci 17:7425-7432. Medline
    • (1997) J Neurosci , vol.17 , pp. 7425-7432
    • Kretzschmar, D.1    Hasan, G.2    Sharma, S.3    Heisenberg, M.4    Benzer, S.5
  • 20
    • 78649759353 scopus 로고    scopus 로고
    • Involvement of notch signaling pathway in amyloid precursor protein induced glial differentiation
    • CrossRef Medline
    • Kwak YD, Marutle A, Dantuma E, Merchant S, Bushnev S, Sugaya K (2011) Involvement of notch signaling pathway in amyloid precursor protein induced glial differentiation. Eur J Pharmacol 650:18-27.CrossRef Medline
    • (2011) Eur J Pharmacol , vol.650 , pp. 18-27
    • Kwak, Y.D.1    Marutle, A.2    Dantuma, E.3    Merchant, S.4    Bushnev, S.5    Sugaya, K.6
  • 22
    • 0030951506 scopus 로고    scopus 로고
    • Defective neurite extension is caused by a mutation in amyloid beta/A4 (A beta) protein precursor found in familial Alzheimer's disease
    • CrossRef Medline
    • Li HL, Roch JM, Sundsmo M, Otero D, Sisodia S, Thomas R, Saitoh T (1997) Defective neurite extension is caused by a mutation in amyloid beta/A4 (A beta) protein precursor found in familial Alzheimer's disease. J Neurobiol 32:469-480.CrossRef Medline
    • (1997) J Neurobiol , vol.32 , pp. 469-480
    • Li, H.L.1    Roch, J.M.2    Sundsmo, M.3    Otero, D.4    Sisodia, S.5    Thomas, R.6    Saitoh, T.7
  • 23
    • 0034652309 scopus 로고    scopus 로고
    • Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein
    • CrossRef Medline
    • Lin X, Koelsch G, Wu S, Downs D, Dashti A, Tang J (2000) Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein. Proc Natl Acad Sci U S A 97:1456-1460.CrossRef Medline
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1456-1460
    • Lin, X.1    Koelsch, G.2    Wu, S.3    Downs, D.4    Dashti, A.5    Tang, J.6
  • 24
    • 0025664016 scopus 로고
    • Identification, secretion, and neural expression of APPL, a Drosophila protein similar to human amyloid protein precursor
    • Medline
    • Luo LQ, Martin-Morris LE, White K (1990) Identification, secretion, and neural expression of APPL, a Drosophila protein similar to human amyloid protein precursor. J Neurosci 10:3849-3861. Medline
    • (1990) J Neurosci , vol.10 , pp. 3849-3861
    • Luo, L.Q.1    Martin-Morris, L.E.2    White, K.3
  • 26
    • 4344610577 scopus 로고    scopus 로고
    • Genes regulated by mating, sperm, or seminal proteins in mated female Drosophila melanogaster
    • CrossRef Medline
    • McGraw LA, Gibson G, Clark AG, Wolfner MF (2004) Genes regulated by mating, sperm, or seminal proteins in mated female Drosophila melanogaster. Curr Biol 14:1509-1514.CrossRef Medline
    • (2004) Curr Biol , vol.14 , pp. 1509-1514
    • McGraw, L.A.1    Gibson, G.2    Clark, A.G.3    Wolfner, M.F.4
  • 27
    • 49649103244 scopus 로고    scopus 로고
    • Promotion of BACE1 mRNA alternative splicing reduces amyloid beta-peptide production
    • CrossRef Medline
    • Mowrer KR, Wolfe MS (2008) Promotion of BACE1 mRNA alternative splicing reduces amyloid beta-peptide production. J Biol Chem 283: 18694-18701.CrossRef Medline
    • (2008) J Biol Chem , vol.283 , pp. 18694-18701
    • Mowrer, K.R.1    Wolfe, M.S.2
  • 28
    • 60549089207 scopus 로고    scopus 로고
    • APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
    • CrossRef Medline
    • Nikolaev A, McLaughlin T, O'Leary DD, Tessier-Lavigne M (2009) APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature: 457:981-989.CrossRef Medline
    • (2009) Nature , vol.457 , pp. 981-989
    • Nikolaev, A.1    McLaughlin, T.2    O'Leary, D.D.3    Tessier-Lavigne, M.4
  • 29
    • 33947247360 scopus 로고    scopus 로고
    • BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice
    • CrossRef Medline
    • Ohno M, Cole SL, Yasvoina M, Zhao J, Citron M, Berry R, Disterhoft JF, Vassar R (2007) BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice. Neurobiol Dis 26:134-145. CrossRef Medline
    • (2007) Neurobiol Dis , vol.26 , pp. 134-145
    • Ohno, M.1    Cole, S.L.2    Yasvoina, M.3    Zhao, J.4    Citron, M.5    Berry, R.6    Disterhoft, J.F.7    Vassar, R.8
  • 30
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • CrossRef Medline
    • Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29:e45.CrossRef Medline
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 33
    • 0027459490 scopus 로고
    • A higher control center of locomotor behavior in the Drosophila brain
    • Medline
    • Strauss R, Heisenberg M (1993) A higher control center of locomotor behavior in the Drosophila brain. J Neurosci 13:1852-1861. Medline
    • (1993) J Neurosci , vol.13 , pp. 1852-1861
    • Strauss, R.1    Heisenberg, M.2
  • 34
    • 0033568874 scopus 로고    scopus 로고
    • The Drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction
    • Medline
    • Torroja L, Packard M, Gorczyca M, White K, Budnik V (1999) The Drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction. J Neurosci 19:7793-7803.Medline
    • (1999) J Neurosci , vol.19 , pp. 7793-7803
    • Torroja, L.1    Packard, M.2    Gorczyca, M.3    White, K.4    Budnik, V.5
  • 36
    • 70350455062 scopus 로고    scopus 로고
    • The beta-secretase enzyme BACE in health and Alzheimer's disease: Regulation, cell biology, function, and therapeutic potential
    • CrossRef Medline
    • Vassar R, Kovacs DM, Yan R, Wong PC (2009) The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential. J Neurosci 29:12787-12794.CrossRef Medline
    • (2009) J Neurosci , vol.29 , pp. 12787-12794
    • Vassar, R.1    Kovacs, D.M.2    Yan, R.3    Wong, P.C.4
  • 37
    • 62349092679 scopus 로고    scopus 로고
    • MCP-1 involvement in glial differentiation of neuroprogenitor cells through APP signaling
    • Cross Ref Medline
    • Vrotsos EG, Kolattukudy PE, Sugaya K (2009) MCP-1 involvement in glial differentiation of neuroprogenitor cells through APP signaling. Brain ResBull 79:97-103.Cross Ref Medline
    • (2009) Brain ResBull , vol.79 , pp. 97-103
    • Vrotsos, E.G.1    Kolattukudy, P.E.2    Sugaya, K.3
  • 38
    • 52049107367 scopus 로고    scopus 로고
    • BACE1 knock-outs display deficits in activity-dependent potentiation of synaptic transmission at mossy fiber to CA3 synapses in the hippocampus
    • CrossRef Medline
    • Wang H, Song L, Laird F, Wong PC, Lee HK (2008) BACE1 knock-outs display deficits in activity-dependent potentiation of synaptic transmission at mossy fiber to CA3 synapses in the hippocampus. J Neurosci 28:8677-8681.CrossRef Medline
    • (2008) J Neurosci , vol.28 , pp. 8677-8681
    • Wang, H.1    Song, L.2    Laird, F.3    Wong, P.C.4    Lee, H.K.5
  • 41
    • 63949088562 scopus 로고    scopus 로고
    • Function, regulation and therapeutic properties of beta-secretase (BACE1)
    • CrossRef Medline
    • Willem M, Lammich S, Haass C (2009) Function, regulation and therapeutic properties of beta-secretase (BACE1). Semin Cell Dev Biol 20: 175-182.CrossRef Medline
    • (2009) Semin Cell Dev Biol , vol.20 , pp. 175-182
    • Willem, M.1    Lammich, S.2    Haass, C.3
  • 44
    • 0035823610 scopus 로고    scopus 로고
    • BACE2 functions asan alternative alpha-secretase in cells
    • Cross Ref Medline
    • Yan R, Munzner J B, Shuck ME, Bienkowski MJ (2001) BACE2 functions asan alternative alpha-secretase in cells. J Biol Chem 276:34019-34027. Cross Ref Medline
    • (2001) J Biol Chem , vol.276 , pp. 34019-34027
    • Yan, R.1    Munzner, J.B.2    Shuck, M.E.3    Bienkowski, M.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.