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Volumn 4, Issue 5, 2012, Pages 537-549

Chromatin regulators with tumor suppressor properties and their alterations in human cancers

Author keywords

chromatin; chromatin remodeling; epigenetic; genetic; histone modification; tumor suppressor

Indexed keywords

BARRIER TO AUTOINTEGRATION FACTOR; BRG1 PROTEIN; BRM PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; HISTONE ACETYLTRANSFERASE PCAF; HISTONE DEACETYLASE 2; HISTONE DEMETHYLASE; HISTONE H1; HISTONE H2A; HISTONE H2B; HISTONE H3; HISTONE H4; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN P53; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SIRTUIN 1; SIRTUIN 2; SIRTUIN 3; TRANSFORMING GROWTH FACTOR BETA;

EID: 84868592742     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.12.50     Document Type: Review
Times cited : (20)

References (124)
  • 1
    • 33847070442 scopus 로고    scopus 로고
    • The role of chromatin during transcription
    • DOI 10.1016/j.cell.2007.01.015, PII S0092867407001092
    • Li B, Carey M, Workman JL. The role of chromatin during transcription. Cell 128(4), 707-719 (2007). (Pubitemid 46273570)
    • (2007) Cell , vol.128 , Issue.4 , pp. 707-719
    • Li, B.1    Carey, M.2    Workman, J.L.3
  • 2
    • 84455200582 scopus 로고    scopus 로고
    • Combinatorial patterning of chromatin regulators uncovered by genome-Wide location analysis in human cells
    • Ram O, Goren A, Amit I et al. Combinatorial patterning of chromatin regulators uncovered by genome-Wide location analysis in human cells. Cell 147(7), 1628-1639 (2011).
    • (2011) Cell , vol.147 , Issue.7 , pp. 1628-1639
    • Ram, O.1    Goren, A.2    Amit, I.3
  • 3
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer - A mechanism for early oncogenic pathway addiction?
    • DOI 10.1038/nrc1799, PII N1799
    • Baylin SB, Ohm JE. Epigenetic gene silencing in cancer - A mechanism for early oncogenic pathway addiction? Nat. Rev. Cancer 6(2), 107-116 (2006). (Pubitemid 43361543)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.2 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 4
    • 79952384705 scopus 로고    scopus 로고
    • Cancer epigenetics reaches mainstream oncology
    • Rodriguez-Paredes M, Esteller M. Cancer epigenetics reaches mainstream oncology. Nat. Med. 17(3), 330-339 (2011).
    • (2011) Nat. Med , vol.17 , Issue.3 , pp. 330-339
    • Rodriguez-Paredes, M.1    Esteller, M.2
  • 5
    • 77953995002 scopus 로고    scopus 로고
    • Covalent hist one modifications - miswritten, misinterpreted and mis-erased in human cancers
    • Chi P, Allis CD, Wang GG. Covalent hist one modifications - miswritten, misinterpreted and mis-erased in human cancers. Nat. Rev. Cancer 10(7), 457-469 (2010).
    • (2010) Nat. Rev. Cancer , vol.10 , Issue.7 , pp. 457-469
    • Chi, P.1    Allis, C.D.2    Wang, G.G.3
  • 6
    • 78651390167 scopus 로고    scopus 로고
    • Long intergenic noncoding RNAs: New links in cancer progression
    • Tsai MC, Spitale RC, Chang HY. Long intergenic noncoding RNAs: New links in cancer progression. Cancer Res. 71(1), 3-7 (2011).
    • (2011) Cancer Res , vol.71 , Issue.1 , pp. 3-7
    • Tsai, M.C.1    Spitale, R.C.2    Chang, H.Y.3
  • 7
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • DOI 10.1016/j.cell.2007.02.005, PII S0092867407001845
    • Kouzarides T. Chromatin modifications and their function. Cell 128(4), 693-705 (2007). (Pubitemid 46273577)
    • (2007) Cell , vol.128 , Issue.4 , pp. 693-705
    • Kouzarides, T.1
  • 8
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • DOI 10.1038/47412
    • Strahl BD, Allis CD. The language of covalent hist one modifications. Nature 403(6765), 41-45 (2000). (Pubitemid 30038513)
    • (2000) Nature , vol.403 , Issue.6765 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 9
    • 78649922622 scopus 로고    scopus 로고
    • The chromatin signaling pathway: Diverse mechanisms of recruitment of hist one-modifying enzymes and varied biological outcomes
    • Smith E, Shilatifard A. The chromatin signaling pathway: Diverse mechanisms of recruitment of hist one-modifying enzymes and varied biological outcomes. Mol. Cell 40(5), 689-701 (2010).
    • (2010) Mol. Cell , vol.40 , Issue.5 , pp. 689-701
    • Smith, E.1    Shilatifard, A.2
  • 10
    • 34547890019 scopus 로고    scopus 로고
    • Functions of site-specific hist one acetylation and deacetylation
    • Shahbazian MD, Grunstein M. Functions of site-specific hist one acetylation and deacetylation. Annu. Rev. Biochem. 76, 75-100 (2007).
    • (2007) Annu. Rev. Biochem , vol.76 , pp. 75-100
    • Shahbazian, M.D.1    Grunstein, M.2
  • 11
    • 30344477367 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
    • DOI 10.1038/nrc1779
    • Minucci S, Pelicci PG. Hist one deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nat. Rev. Cancer 6(1), 38-51 (2006). (Pubitemid 43054973)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.1 , pp. 38-51
    • Minucci, S.1    Pelicci, P.G.2
  • 12
    • 0030797585 scopus 로고    scopus 로고
    • Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
    • DOI 10.1016/S0092-8674(00)80521-8
    • Gu W, Roeder RG. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 90(4), 595-606 (1997). (Pubitemid 27357952)
    • (1997) Cell , vol.90 , Issue.4 , pp. 595-606
    • Gu, W.1    Roeder, R.G.2
  • 13
    • 0035868964 scopus 로고    scopus 로고
    • P300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2
    • DOI 10.1093/emboj/20.6.1331
    • Ito A, Lai CH, Zhao X et al. p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2. EMBO J. 20(6), 1331-1340 (2001). (Pubitemid 32233973)
    • (2001) EMBO Journal , vol.20 , Issue.6 , pp. 1331-1340
    • Ito, A.1    Lai, C.-H.2    Zhao, X.3    Saito, S.4    Hamilton, M.H.5    Appella, E.6    Yao, T.-P.7
  • 17
    • 0029022770 scopus 로고
    • Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP
    • Petrij F, Giles RH, Dauwerse HG et al. Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP. Nature 376(6538), 348-351 (1995).
    • (1995) Nature , vol.376 , Issue.6538 , pp. 348-351
    • Petrij, F.1    Giles, R.H.2    Dauwerse, H.G.3
  • 18
    • 9544220768 scopus 로고    scopus 로고
    • The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-Binding protein
    • Borrow J, Stanton VP Jr, Andresen JM et al. The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-Binding protein. Nat. Genet. 14(1), 33-41 (1996).
    • (1996) Nat. Genet , vol.14 , Issue.1 , pp. 33-41
    • Borrow, J.1    Stanton Jr., V.P.2    Andresen, J.M.3
  • 19
    • 0344441910 scopus 로고    scopus 로고
    • PCAF is a coactivator for p73-mediated transactivation
    • DOI 10.1038/sj.onc.1206916
    • Zhao LY, Liu Y, Bertos NR, Yang XJ, Liao D. PCAF is a coactivator for p73-mediated transactivation. Oncogene 22(51), 8316-8329 (2003). (Pubitemid 37485524)
    • (2003) Oncogene , vol.22 , Issue.51 , pp. 8316-8329
    • Zhao, L.Y.1    Liu, Y.2    Bertos, N.R.3    Yang, X.-J.4    Liao, D.5
  • 20
    • 68349125550 scopus 로고    scopus 로고
    • Characterization of tumor suppressive function of P300/ CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma
    • Zhu C, Qin YR, Xie D et al. Characterization of tumor suppressive function of P300/ CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma. Oncogene 28(31), 2821-2828 (2009).
    • (2009) Oncogene , vol.28 , Issue.31 , pp. 2821-2828
    • Zhu, C.1    Qin, Y.R.2    Xie, D.3
  • 22
    • 1842631408 scopus 로고    scopus 로고
    • Upregulation and nuclear recruitment of HDACl in hormone refractory prostate cancer
    • DOI 10.1002/pros.20022
    • Halkidou K, Gaughan L, Cook S, Leung HY, Neal DE, Robson CN. Upregulation and nuclear recruitment of HDAC1 in hormOne refractory prostate cancer. Prostate 59(2), 177-189 (2004). (Pubitemid 38481229)
    • (2004) Prostate , vol.59 , Issue.2 , pp. 177-189
    • Halkidou, K.1    Gaughan, L.2    Cook, S.3    Leung, H.Y.4    Neal, D.E.5    Robson, C.N.6
  • 24
    • 33748451151 scopus 로고    scopus 로고
    • Anticancer activities of histone deacetylase inhibitors
    • DOI 10.1038/nrd2133, PII NRD2133
    • Bolden JE, Peart MJ, JohnstOne RW. Anticancer activities of hist one deacetylase inhibitors. Nat. Rev. Drug Discov. 5(9), 769-784 (2006). (Pubitemid 44348499)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.9 , pp. 769-784
    • Bolden, J.E.1    Peart, M.J.2    Johnstone, R.W.3
  • 25
    • 33646354640 scopus 로고    scopus 로고
    • A truncating mutation of HDAC2 in human cancers confers resistance to hist one deacetylase inhibition
    • Ropero S, Fraga MF, Ballestar E et al. A truncating mutation of HDAC2 in human cancers confers resistance to hist one deacetylase inhibition. Nat. Genet. 38(5), 566-569 (2006).
    • (2006) Nat. Genet , vol.38 , Issue.5 , pp. 566-569
    • Ropero, S.1    Fraga, M.F.2    Ballestar, E.3
  • 26
    • 2942722811 scopus 로고    scopus 로고
    • Molecular mechanisms of E2F-dependent activation and pRB-mediated repression
    • DOI 10.1242/jcs.01227
    • Frolov MV, Dyson NJ. Molecular mechanisms of E2F-dependent activation and pRB-mediated repression. J. Cell. Sci. 117(PT11), 2173-2181 (2004). (Pubitemid 38807486)
    • (2004) Journal of Cell Science , vol.117 , Issue.11 , pp. 2173-2181
    • Frolov, M.V.1    Dyson, N.J.2
  • 27
    • 77957266345 scopus 로고    scopus 로고
    • Aging and cancer: Are sirtuins the link
    • Rodriguez RM, Fraga MF. Aging and cancer: Are sirtuins the link? Future Oncol. 6(6), 905-915 (2010).
    • (2010) Future Oncol , vol.6 , Issue.6 , pp. 905-915
    • Rodriguez, R.M.1    Fraga, M.F.2
  • 28
    • 34547875773 scopus 로고    scopus 로고
    • Sirtuins: Critical regulators at the crossroads between cancer and aging
    • DOI 10.1038/sj.onc.1210616, PII 1210616
    • Saunders LR, Verdin E. Sirtuins: Critical regulators at the crossroads between cancer and aging. Oncogene 26(37), 5489-5504 (2007). (Pubitemid 47255930)
    • (2007) Oncogene , vol.26 , Issue.37 , pp. 5489-5504
    • Saunders, L.R.1    Verdin, E.2
  • 29
    • 53149137486 scopus 로고    scopus 로고
    • Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
    • Wang RH, Sengupta K, Li C et al. Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell 14(4), 312-323 (2008).
    • (2008) Cancer Cell , vol.14 , Issue.4 , pp. 312-323
    • Wang, R.H.1    Sengupta, K.2    Li, C.3
  • 30
    • 79551521179 scopus 로고    scopus 로고
    • Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation
    • Powell MJ, Casimiro MC, Cordon-Cardo C et al. Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation. Cancer Res. 71(3), 964-975 (2010).
    • (2010) Cancer Res , vol.71 , Issue.3 , pp. 964-975
    • Powell, M.J.1    Casimiro, M.C.2    Cordon-Cardo, C.3
  • 31
    • 80054769188 scopus 로고    scopus 로고
    • SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity
    • Kim HS, Vassilopoulos A, Wang RH et al. SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity. Cancer Cell 20(4), 487-499 (2011).
    • (2011) Cancer Cell , vol.20 , Issue.4 , pp. 487-499
    • Kim, H.S.1    Vassilopoulos, A.2    Wang, R.H.3
  • 32
    • 79952501323 scopus 로고    scopus 로고
    • SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
    • Finley LW, Carracedo A, Lee J et al. SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization. Cancer Cell 19(3), 416-428 (2011).
    • (2011) Cancer Cell , vol.19 , Issue.3 , pp. 416-428
    • Finley, L.W.1    Carracedo, A.2    Lee, J.3
  • 33
    • 76049100577 scopus 로고    scopus 로고
    • HIF-1: Upstream and downstream of cancer metabolism
    • Semenza GL. HIF-1: Upstream and downstream of cancer metabolism. Curr. Opin. Genet. Dev. 20(1), 51-56 (2010).
    • (2010) Curr. Opin. Genet. Dev , vol.20 , Issue.1 , pp. 51-56
    • Semenza, G.L.1
  • 34
    • 74049094817 scopus 로고    scopus 로고
    • SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
    • Kim HS, Patel K, Muldoon-Jacobs K et al. SIRT3 is a mitochondria- localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. Cancer Cell 17(1), 41-52 (2010).
    • (2010) Cancer Cell , vol.17 , Issue.1 , pp. 41-52
    • Kim, H.S.1    Patel, K.2    Muldoon-Jacobs, K.3
  • 35
    • 77953644347 scopus 로고    scopus 로고
    • Reversal of hist one methylation: Biochemical and molecular mechanisms of hist one demethylases
    • Mosammaparast N, Shi Y. Reversal of hist one methylation: Biochemical and molecular mechanisms of hist one demethylases. Annu. Rev. Biochem. 79, 155-179 (2010).
    • (2010) Annu. Rev. Biochem , vol.79 , pp. 155-179
    • Mosammaparast, N.1    Shi, Y.2
  • 36
    • 78751590899 scopus 로고    scopus 로고
    • Silencing chromatin: Comparing modes and mechanisms
    • Beisel C, Paro R. Silencing chromatin: Comparing modes and mechanisms. Nat. Rev. Genet. 12(2), 123-135 (2011).
    • (2011) Nat. Rev. Genet , vol.12 , Issue.2 , pp. 123-135
    • Beisel, C.1    Paro, R.2
  • 38
    • 0345275880 scopus 로고    scopus 로고
    • Inactivation of a Histone Methyltransferase by Mutations in Human Cancers
    • Kim KC, Geng L, Huang S. Inactivation of a hist one methyltransferase by mutations in human cancers. Cancer Res. 63(22), 7619-7623 (2003). (Pubitemid 37466684)
    • (2003) Cancer Research , vol.63 , Issue.22 , pp. 7619-7623
    • Kim, K.-C.1    Geng, L.2    Huang, S.3
  • 39
    • 0035890771 scopus 로고    scopus 로고
    • Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily
    • Du Y, Carling T, Fang W, Piao Z, Sheu JC, Huang S. Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a hist one/protein methyltransferase superfamily. Cancer Res. 61(22), 8094-8099 (2001). (Pubitemid 33091596)
    • (2001) Cancer Research , vol.61 , Issue.22 , pp. 8094-8099
    • Du, Y.1    Carling, T.2    Fang, W.3    Piao, Z.4    Sheu, J.-C.5    Huang, S.6
  • 41
    • 46849115153 scopus 로고    scopus 로고
    • Hist one methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes
    • Xie P, Tian C, An L et al. Hist one methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes. Cell Signal 20(9), 1671-1678 (2008).
    • (2008) Cell Signal , vol.20 , Issue.9 , pp. 1671-1678
    • Xie, P.1    Tian, C.2    An, L.3
  • 43
    • 80051733367 scopus 로고    scopus 로고
    • P53-dependent transcription and tumor suppression are not affected in Set7/9-deficient mice
    • Lehnertz B, Rogalski JC, Schulze FM et al. p53-dependent transcription and tumor suppression are not affected in Set7/9-deficient mice. Mol. Cell 43(4), 673-680 (2011).
    • (2011) Mol. Cell , vol.43 , Issue.4 , pp. 673-680
    • Lehnertz, B.1    Rogalski, J.C.2    Schulze, F.M.3
  • 44
    • 70049111751 scopus 로고    scopus 로고
    • The mRNA expression of SETD2 in human breast cancer: Correlation with clinico-Pathological parameters
    • Al Sarakbi W, Sasi W, Jiang WG, Roberts T, Newbold RF, Mokbel K. The mRNA expression of SETD2 in human breast cancer: Correlation with clinico-Pathological parameters. BMC Cancer 9, 290 (2009).
    • (2009) BMC Cancer , vol.9 , pp. 290
    • Al Sarakbi, W.1    Sasi, W.2    Jiang, W.G.3    Roberts, T.4    Newbold, R.F.5    Mokbel, K.6
  • 45
    • 75149188170 scopus 로고    scopus 로고
    • Systematic sequencing of renal carcinoma reveals inactivation of hist one modifying genes
    • Dalgliesh GL, Furge K, Greenman C et al. Systematic sequencing of renal carcinoma reveals inactivation of hist one modifying genes. Nature 463(7279), 360-363 (2010).
    • (2010) Nature , vol.463 , Issue.7279 , pp. 360-363
    • Dalgliesh, G.L.1    Furge, K.2    Greenman, C.3
  • 46
    • 77953170322 scopus 로고    scopus 로고
    • Hist one methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma
    • Duns G, van den Berg E, van Duivenbode I et al. Hist one methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma. Cancer Res. 70(11), 4287-4291 (2010).
    • (2010) Cancer Res , vol.70 , Issue.11 , pp. 4287-4291
    • Duns, G.1    Van Den Berg, E.2    Van Duivenbode, I.3
  • 47
    • 84862907593 scopus 로고    scopus 로고
    • The genetic basis of early T-Cell precursor acute lymphoblastic leukaemia
    • Zhang J, Ding L, Holmfeldt L et al. The genetic basis of early T-Cell precursor acute lymphoblastic leukaemia. Nature 481(7380), 157-163 (2012).
    • (2012) Nature , vol.481 , Issue.7380 , pp. 157-163
    • Zhang, J.1    Ding, L.2    Holmfeldt, L.3
  • 48
    • 79959272481 scopus 로고    scopus 로고
    • Cancers and the NSD family of hist one lysine methyltransferases
    • Morishita M, di Luccio E. Cancers and the NSD family of hist one lysine methyltransferases. Biochim. Biophys. Acta 1816(2), 158-163 (2011).
    • (2011) Biochim. Biophys. Acta , vol.1816 , Issue.2 , pp. 158-163
    • Morishita, M.1    Di Luccio, E.2
  • 49
    • 42449161943 scopus 로고    scopus 로고
    • The MMSET protein is a hist one methyltransferase with characteristics of a transcriptional corepressor
    • Marango J, Shimoyama M, Nishio H et al. The MMSET protein is a hist one methyltransferase with characteristics of a transcriptional corepressor. Blood 111(6), 3145-3154 (2008).
    • (2008) Blood , vol.111 , Issue.6 , pp. 3145-3154
    • Marango, J.1    Shimoyama, M.2    Nishio, H.3
  • 50
    • 76049084596 scopus 로고    scopus 로고
    • Epigenetic inactivation of the Sotos overgrowth syndrome gene hist one methyltransferase NSD1 in human neuroblastoma and glioma
    • Berdasco M, Ropero S, Setien F et al. Epigenetic inactivation of the Sotos overgrowth syndrome gene hist one methyltransferase NSD1 in human neuroblastoma and glioma. Proc. Natl Acad. Sci. USA 106(51), 21830-21835 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.51 , pp. 21830-21835
    • Berdasco, M.1    Ropero, S.2    Setien, F.3
  • 51
    • 33847049891 scopus 로고    scopus 로고
    • The histone methyltransferase activity of WHISTLE is important for the induction of apoptosis and HDAC1-mediated transcriptional repression
    • DOI 10.1016/j.yexcr.2006.12.007, PII S0014482706005180
    • Kim SM, Kee HJ, Choe N, Kim JY, Kook H, Seo SB. The hist one methyltransferase activity of WHISTLE is important for the induction of apoptosis and HDAC1- mediated transcriptional repression. Exp. Cell Res. 313(5), 975-983 (2007). (Pubitemid 46273444)
    • (2007) Experimental Cell Research , vol.313 , Issue.5 , pp. 975-983
    • Kim, S.-M.1    Kee, H.-J.2    Choe, N.3    Kim, J.-Y.4    Kook, H.5    Kook, H.6    Seo, S.-B.7
  • 52
    • 77955268518 scopus 로고    scopus 로고
    • The NSD3L hist one methyltransferase regulates cell cycle and cell invasion in breast cancer cells
    • Zhou Z, Thomsen R, Kahns S, Nielsen AL. The NSD3L hist one methyltransferase regulates cell cycle and cell invasion in breast cancer cells. Biochem. Biophys. Res. Commun. 398(3), 565-570 (2010).
    • (2010) Biochem. Biophys. Res. Commun , vol.398 , Issue.3 , pp. 565-570
    • Zhou, Z.1    Thomsen, R.2    Kahns, S.3    Nielsen, A.L.4
  • 53
    • 35349006314 scopus 로고    scopus 로고
    • Histone lysine demethylases: Emerging roles in development, physiology and disease
    • DOI 10.1038/nrg2218, PII NRG2218
    • Shi Y. Hist one lysine demethylases: Emerging roles in development, physiology and disease. Nat. Rev. Genet. 8(11), 829-833 (2007). (Pubitemid 47609092)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.11 , pp. 829-833
    • Shi, Y.1
  • 54
    • 11144332565 scopus 로고    scopus 로고
    • Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
    • DOI 10.1016/j.cell.2004.12.012, PII S0092867404011997
    • Shi Y, Lan F, Matson C et al. Hist one demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119(7), 941-953 (2004). (Pubitemid 40037608)
    • (2004) Cell , vol.119 , Issue.7 , pp. 941-953
    • Shi, Y.1    Lan, F.2    Matson, C.3    Mulligan, P.4    Whetstine, J.R.5    Cole, P.A.6    Casero, R.A.7    Shi, Y.8
  • 55
    • 68749108259 scopus 로고    scopus 로고
    • LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer
    • Wang Y, Zhang H, Chen Y et al. LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer. Cell 138(4), 660-672 (2009).
    • (2009) Cell , vol.138 , Issue.4 , pp. 660-672
    • Wang, Y.1    Zhang, H.2    Chen, Y.3
  • 56
    • 78649815150 scopus 로고    scopus 로고
    • Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers
    • Hayami S, Kelly JD, Cho HS et al. Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers. Int. J. Cancer 128(3), 574-586 (2010).
    • (2010) Int. J. Cancer , vol.128 , Issue.3 , pp. 574-586
    • Hayami, S.1    Kelly, J.D.2    Cho, H.S.3
  • 58
    • 84862123313 scopus 로고    scopus 로고
    • The hist one demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells
    • Harris WJ, Huang X, Lynch JT et al. The hist one demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells. Cancer Cell 21(4), 473-487 (2012).
    • (2012) Cancer Cell , vol.21 , Issue.4 , pp. 473-487
    • Harris, W.J.1    Huang, X.2    Lynch, J.T.3
  • 60
    • 67349203626 scopus 로고    scopus 로고
    • Somatic mutations of the hist one H3K27 demethylase gene UTX in human cancer
    • van Haaften G, Dalgliesh GL, Davies H et al. Somatic mutations of the hist one H3K27 demethylase gene UTX in human cancer. Nat. Genet. 41(5), 521-523 (2009).
    • (2009) Nat. Genet , vol.41 , Issue.5 , pp. 521-523
    • Van Haaften, G.1    Dalgliesh, G.L.2    Davies, H.3
  • 61
    • 77951980558 scopus 로고    scopus 로고
    • The H3K27me3 demethylase dUTX is a suppressor of Notch- And Rb-dependent tumors in Drosophila
    • Herz HM, Madden LD, Chen Z et al. The H3K27me3 demethylase dUTX is a suppressor of Notch- And Rb-dependent tumors in Drosophila. Mol. Cell. Biol. 30(10), 2485-2497 (2010).
    • (2010) Mol. Cell. Biol , vol.30 , Issue.10 , pp. 2485-2497
    • Herz, H.M.1    Madden, L.D.2    Chen, Z.3
  • 62
    • 76749139057 scopus 로고    scopus 로고
    • The hist one demethylase UTX enables RB-dependent cell fate control
    • Wang JK, Tsai MC, Poulin G et al. The hist one demethylase UTX enables RB-dependent cell fate control. Genes Dev. 24(4), 327-332 (2010).
    • (2010) Genes Dev , vol.24 , Issue.4 , pp. 327-332
    • Wang, J.K.1    Tsai, M.C.2    Poulin, G.3
  • 63
    • 66149138053 scopus 로고    scopus 로고
    • The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene-and stress-induced senescence
    • Agger K, Cloos PA, Rudkjaer L et al. The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene-and stress-induced senescence. Genes Dev. 23(10), 1171-1176 (2009).
    • (2009) Genes Dev , vol.23 , Issue.10 , pp. 1171-1176
    • Agger, K.1    Cloos, P.A.2    Rudkjaer, L.3
  • 64
    • 84856955226 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through hist one demethylase JARID1C
    • Niu X, Zhang T, Liao L et al. The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through hist one demethylase JARID1C. Oncogene 31(6), 776-786 (2011).
    • (2011) Oncogene , vol.31 , Issue.6 , pp. 776-786
    • Niu, X.1    Zhang, T.2    Liao, L.3
  • 65
    • 84862966741 scopus 로고    scopus 로고
    • Increased expression of hist one demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-Regulating angiogenesis
    • Osawa T, Muramatsu M, Wang F et al. Increased expression of hist one demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-Regulating angiogenesis. Proc. Natl Acad. Sci. USA 108(51), 20725-20729 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , Issue.51 , pp. 20725-20729
    • Osawa, T.1    Muramatsu, M.2    Wang, F.3
  • 66
    • 80155131102 scopus 로고    scopus 로고
    • Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14
    • Li Q, Shi L, Gui B et al. Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14. Cancer Res. 71(21), 6899-6908 (2011).
    • (2011) Cancer Res , vol.71 , Issue.21 , pp. 6899-6908
    • Li, Q.1    Shi, L.2    Gui, B.3
  • 67
    • 80053203114 scopus 로고    scopus 로고
    • The hist one demethylase Jarid1b (Kdm5b) is a novel compOnent of the Rb pathway and associates with E2f-target genes in MEFs during senescence
    • Nijwening JH, Geutjes EJ, Bernards R, Beijersbergen RL. The hist one demethylase Jarid1b (Kdm5b) is a novel compOnent of the Rb pathway and associates with E2f-target genes in MEFs during senescence. Plos One 6(9), e25235 (2011).
    • (2011) Plos One , vol.6 , Issue.9
    • Nijwening, J.H.1    Geutjes, E.J.2    Bernards, R.3    Beijersbergen, R.L.4
  • 68
    • 75749101495 scopus 로고    scopus 로고
    • Chromatin remodelling during development
    • Ho L, Crabtree GR. Chromatin remodelling during development. Nature 463(7280), 474-484 (2010).
    • (2010) Nature , vol.463 , Issue.7280 , pp. 474-484
    • Ho, L.1    Crabtree, G.R.2
  • 69
    • 1042290351 scopus 로고    scopus 로고
    • The SWI/SNF complex - Chromatin and cancer
    • Roberts CW, Orkin SH. The SWI/SNF complex - chromatin and cancer. Nat. Rev. Cancer 4(2), 133-142 (2004). (Pubitemid 38198741)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.2 , pp. 133-142
    • Roberts, C.W.M.1    Orkin, S.H.2
  • 70
    • 79959653996 scopus 로고    scopus 로고
    • SWI/SNF nucleosome remodellers and cancer
    • Wilson BG, Roberts CW. SWI/SNF nucleosome remodellers and cancer. Nat. Rev. Cancer 11(7), 481-492 (2011).
    • (2011) Nat. Rev. Cancer , vol.11 , Issue.7 , pp. 481-492
    • Wilson, B.G.1    Roberts, C.W.2
  • 73
    • 0034610395 scopus 로고    scopus 로고
    • Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice
    • Roberts CW, Galusha SA, McMenamin ME, Fletcher CD, Orkin SH. Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice. Proc. Natl Acad. Sci. USA 97(25), 13796-13800 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , Issue.25 , pp. 13796-13800
    • Roberts, C.W.1    Galusha, S.A.2    McMenamin, M.E.3    Fletcher, C.D.4    Orkin, S.H.5
  • 74
    • 0042452295 scopus 로고    scopus 로고
    • Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5
    • DOI 10.1016/S1535-6108(02)00185-X
    • Roberts CW, Leroux MM, Fleming MD, Orkin SH. Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5. Cancer Cell 2(5), 415-425 (2002). (Pubitemid 41039107)
    • (2002) Cancer Cell , vol.2 , Issue.5 , pp. 415-425
    • Roberts, C.W.M.1    Leroux, M.M.2    Fleming, M.D.3    Orkin, S.H.4
  • 77
    • 77957955244 scopus 로고    scopus 로고
    • Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation
    • Wilson BG, Wang X, Shen X et al. Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation. Cancer Cell 18(4), 316-328 (2010).
    • (2010) Cancer Cell , vol.18 , Issue.4 , pp. 316-328
    • Wilson, B.G.1    Wang, X.2    Shen, X.3
  • 78
    • 53549095222 scopus 로고    scopus 로고
    • Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability
    • McKenna ES, Sansam CG, Cho YJ et al. Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability. Mol. Cell. Biol. 28(20), 6223-6233 (2008).
    • (2008) Mol. Cell. Biol , vol.28 , Issue.20 , pp. 6223-6233
    • McKenna, E.S.1    Sansam, C.G.2    Cho, Y.J.3
  • 80
    • 0034326257 scopus 로고    scopus 로고
    • BRG1, a compOnent of the SWI-SNF complex, is mutated in multiple human tumor cell lines
    • Wong AK, Shanahan F, Chen Y et al. BRG1, a compOnent of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res. 60(21), 6171-6177 (2000).
    • (2000) Cancer Res , vol.60 , Issue.21 , pp. 6171-6177
    • Wong, A.K.1    Shanahan, F.2    Chen, Y.3
  • 81
    • 79551572835 scopus 로고    scopus 로고
    • Massive parallel DNA pyrosequencing analysis of the tumor suppressor BRG1/SMARCA4 in lung primary tumors
    • Rodriguez-Nieto S, Canada A, Pros E et al. Massive parallel DNA pyrosequencing analysis of the tumor suppressor BRG1/SMARCA4 in lung primary tumors. Hum. Mutat. 32(2), e1999-e2017 (2011).
    • (2011) Hum. Mutat , vol.32 , Issue.2
    • Rodriguez-Nieto, S.1    Canada, A.2    Pros, E.3
  • 82
    • 79957603182 scopus 로고    scopus 로고
    • BRM and BRG1 subunits of the SWI/SNF chromatin remodelling complex are downregulated upon progression of benign skin lesions into invasive tumours
    • Bock VL, Lyons JG, Huang XX et al. BRM and BRG1 subunits of the SWI/SNF chromatin remodelling complex are downregulated upon progression of benign skin lesions into invasive tumours. Br. J. Dermatol. 164(6), 1221-1227 (2011).
    • (2011) Br. J. Dermatol , vol.164 , Issue.6 , pp. 1221-1227
    • Bock, V.L.1    Lyons, J.G.2    Huang, X.X.3
  • 83
    • 57749113070 scopus 로고    scopus 로고
    • The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer
    • Shen H, Powers N, Saini N et al. The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer. Cancer Res. 68(24), 10154-10162 (2008).
    • (2008) Cancer Res , vol.68 , Issue.24 , pp. 10154-10162
    • Shen, H.1    Powers, N.2    Saini, N.3
  • 84
    • 77957801917 scopus 로고    scopus 로고
    • The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB-P53 pathways
    • Alessio N, Squillaro T, Cipollaro M, Bagella L, Giordano A, Galderisi U. The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB-P53 pathways. Oncogene 29(40), 5452-5463 (2010).
    • (2010) Oncogene , vol.29 , Issue.40 , pp. 5452-5463
    • Alessio, N.1    Squillaro, T.2    Cipollaro, M.3    Bagella, L.4    Giordano, A.5    Galderisi, U.6
  • 87
    • 61349129513 scopus 로고    scopus 로고
    • The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a
    • Becker TM, Haferkamp S, Dijkstra MK et al. The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a. Mol. Cancer 8, 4 (2009).
    • (2009) Mol. Cancer , vol.8 , pp. 4
    • Becker, T.M.1    Haferkamp, S.2    Dijkstra, M.K.3
  • 89
    • 38349010480 scopus 로고    scopus 로고
    • Characterization of mammary tumors from Brg1 heterozygous mice
    • Bultman SJ, Herschkowitz JI, Godfrey V et al. Characterization of mammary tumors from Brg1 heterozygous mice. Oncogene 27(4), 460-468 (2008).
    • (2008) Oncogene , vol.27 , Issue.4 , pp. 460-468
    • Bultman, S.J.1    Herschkowitz, J.I.2    Godfrey, V.3
  • 90
    • 34250360362 scopus 로고    scopus 로고
    • Genomic and functional evidence for an ARID1A tumor suppressor role
    • DOI 10.1002/gcc.20459
    • Huang J, Zhao YL, Li Y, Fletcher JA, Xiao S. Genomic and functional evidence for an ARID1A tumor suppressor role. Genes Chromosomes Cancer 46(8), 745-750 (2007). (Pubitemid 46912345)
    • (2007) Genes Chromosomes and Cancer , vol.46 , Issue.8 , pp. 745-750
    • Huang, J.1    Zhao, Y.-L.2    Li, Y.3    Fletcher, J.A.4    Xiao, S.5
  • 91
    • 84859899141 scopus 로고    scopus 로고
    • An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer
    • Mamo A, CavallOne L, Tuzmen S et al. An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer. Oncogene 31(16), 2090-2100 (2012).
    • (2012) Oncogene , vol.31 , Issue.16 , pp. 2090-2100
    • Mamo, A.1    CavallOne, L.2    Tuzmen, S.3
  • 92
    • 77957731999 scopus 로고    scopus 로고
    • Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma
    • Jones S, Wang TL, Shih IeM et al. Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science 330(6001), 228-231 (2010).
    • (2010) Science 330 , vol.6001 , pp. 228-231
    • Jones, S.1    Wang, T.L.2    Shih, IeM.3
  • 93
    • 77957946398 scopus 로고    scopus 로고
    • ARID1A mutations in endometriosis-associated ovarian carcinomas
    • Wiegand KC, Shah SP, Al-Agha OM et al. ARID1A mutations in endometriosis-associated ovarian carcinomas. N. Engl. J. Med. 363(16), 1532-1543 (2010).
    • (2010) N. Engl. J. Med , vol.363 , Issue.16 , pp. 1532-1543
    • Wiegand, K.C.1    Shah, S.P.2    Al-Agha, O.M.3
  • 94
    • 82255183148 scopus 로고    scopus 로고
    • Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
    • Wang K, Kan J, Yuen ST et al. Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer. Nat. Genet. 43(12), 1219-1223 (2011).
    • (2011) Nat. Genet , vol.43 , Issue.12 , pp. 1219-1223
    • Wang, K.1    Kan, J.2    Yuen, S.T.3
  • 95
    • 84857467474 scopus 로고    scopus 로고
    • Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types
    • Jones S, Li M, Parsons DW et al. Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types. Hum. Mutat. 33(1), 100-103 (2012).
    • (2012) Hum. Mutat , vol.33 , Issue.1 , pp. 100-103
    • Jones, S.1    Li, M.2    Parsons, D.W.3
  • 96
    • 84862976633 scopus 로고    scopus 로고
    • Whole-Genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
    • Fujimoto A, Totoki Y, Abe T et al. Whole-Genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat. Genet. 44(7), 760-764 (2012).
    • (2012) Nat. Genet , vol.44 , Issue.7 , pp. 760-764
    • Fujimoto, A.1    Totoki, Y.2    Abe, T.3
  • 97
    • 32944462855 scopus 로고    scopus 로고
    • The c-myc gene is a direct target of mammalian SWI/SNF-related complexes during differentiation-associated cell cycle arrest
    • DOI 10.1158/0008-5472.CAN-05-3427
    • Nagl NG Jr, Zweitzig DR, Thimmapaya B, Beck GR Jr, Moran E. The c-myc gene is a direct target of mammalian SWI/SNF-Related complexes during differentiation-associated cell cycle arrest. Cancer Res. 66(3), 1289-1293 (2006). (Pubitemid 43259906)
    • (2006) Cancer Research , vol.66 , Issue.3 , pp. 1289-1293
    • Nagl Jr., N.G.1    Zweitzig, D.R.2    Thimmapaya, B.3    Beck Jr., G.R.4    Moran, E.5
  • 98
    • 80155131218 scopus 로고    scopus 로고
    • ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers
    • Guan B, Wang TL, Shih IeM. ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers. Cancer Res. 71(21), 6718-6727 (2011).
    • (2011) Cancer Res , vol.71 , Issue.21 , pp. 6718-6727
    • Guan, B.1    Wang, T.L.2    ShihIe, M.3
  • 99
    • 80052271807 scopus 로고    scopus 로고
    • Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma
    • Li M, Zhao H, Zhang X et al. Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma. Nat. Genet. 43(9), 828-829 (2011).
    • (2011) Nat. Genet , vol.43 , Issue.9 , pp. 828-829
    • Li, M.1    Zhao, H.2    Zhang, X.3
  • 100
    • 23044461703 scopus 로고    scopus 로고
    • PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes
    • DOI 10.1101/gad.1323805
    • Yan Z, Cui K, Murray DM et al. PBAF chromatin-Remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-Responsive genes. Genes Dev. 19(14), 1662-1667 (2005). (Pubitemid 41058360)
    • (2005) Genes and Development , vol.19 , Issue.14 , pp. 1662-1667
    • Yan, Z.1    Cui, K.2    Murray, D.M.3    Ling, C.4    Xue, Y.5    Gerstein, A.6    Parsons, R.7    Zhao, K.8    Wang, W.9
  • 102
    • 79251635938 scopus 로고    scopus 로고
    • Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
    • Varela I, Tarpey P, Raine K et al. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 469(7331), 539-542 (2011).
    • (2011) Nature , vol.469 , Issue.7331 , pp. 539-542
    • Varela, I.1    Tarpey, P.2    Raine, K.3
  • 103
    • 77950517628 scopus 로고    scopus 로고
    • BRD7 is a candidate tumour suppressor gene required for p53 function
    • Drost J, Mantovani F, Tocco F et al. BRD7 is a candidate tumour suppressor gene required for p53 function. Nat. Cell. Biol. 12(4), 380-389 (2010).
    • (2010) Nat. Cell. Biol , vol.12 , Issue.4 , pp. 380-389
    • Drost, J.1    Mantovani, F.2    Tocco, F.3
  • 104
    • 52449133461 scopus 로고    scopus 로고
    • Promoter methylation inhibits BRD7 expression in human nasopharyngeal carcinoma cells
    • Liu H, Zhang L, Niu Z et al. Promoter methylation inhibits BRD7 expression in human nasopharyngeal carcinoma cells. BMC Cancer 8, 253 (2008).
    • (2008) BMC Cancer , vol.8 , pp. 253
    • Liu, H.1    Zhang, L.2    Niu, Z.3
  • 105
    • 79954505570 scopus 로고    scopus 로고
    • SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis
    • Lin JR, Zeman MK, Chen JY, Yee MC, Cimprich KA. SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis. Mol. Cell 42(2), 237-249 (2011).
    • (2011) Mol. Cell , vol.42 , Issue.2 , pp. 237-249
    • Lin, J.R.1    Zeman, M.K.2    Chen, J.Y.3    Yee, M.C.4    Cimprich, K.A.5
  • 107
    • 0141813518 scopus 로고    scopus 로고
    • DNA hypermethylation and histone hypoacetylation of the HLTF gene are associated with reduced expression in gastric carcinoma
    • DOI 10.1111/j.1349-7006.2003.tb01504.x
    • Hamai Y, Oue N, Mitani Y et al. DNA hypermethylation and hist one hypoacetylation of the HLTF gene are associated with reduced expression in gastric carcinoma. Cancer Sci. 94(8), 692-698 (2003). (Pubitemid 37160926)
    • (2003) Cancer Science , vol.94 , Issue.8 , pp. 692-698
    • Hamai, Y.1    Oue, N.2    Mitani, Y.3    Nakayama, H.4    Ito, R.5    Matsusaki, K.6    Yoshida, K.7    Toge, T.8    Yasui, W.9
  • 108
    • 67651158856 scopus 로고    scopus 로고
    • Methylation of helicase-like transcription factor in serum of patients with colorectal cancer is an independent predictor of disease recurrence
    • Herbst A, Wallner M, Rahmig K et al. Methylation of helicase-like transcription factor in serum of patients with colorectal cancer is an independent predictor of disease recurrence. Eur. J. Gastroenterol. Hepatol. 21(5), 565-569 (2009).
    • (2009) Eur. J. Gastroenterol. Hepatol , vol.21 , Issue.5 , pp. 565-569
    • Herbst, A.1    Wallner, M.2    Rahmig, K.3
  • 109
    • 33645321637 scopus 로고    scopus 로고
    • Promoter methylation of helicase-like transcription factor is associated with the early stages of gastric cancer with family history
    • Kim JJ, Chung SW, Kim JH et al. Promoter methylation of helicase-like transcription factor is associated with the early stages of gastric cancer with family history. Ann. Oncol. 17(4), 657-662 (2006).
    • (2006) Ann. Oncol , vol.17 , Issue.4 , pp. 657-662
    • Kim, J.J.1    Chung, S.W.2    Kim, J.H.3
  • 110
    • 61349151633 scopus 로고    scopus 로고
    • Role of chromodomain helicase DNA-Binding protein 2 in DNA damage response signaling and tumorigenesis
    • Nagarajan P, Onami TM, Rajagopalan S, Kania S, Donnell R, Venkatachalam S. Role of chromodomain helicase DNA-Binding protein 2 in DNA damage response signaling and tumorigenesis. Oncogene 28(8), 1053-1062 (2009).
    • (2009) Oncogene , vol.28 , Issue.8 , pp. 1053-1062
    • Nagarajan, P.1    Onami, T.M.2    Rajagopalan, S.3    Kania, S.4    Donnell, R.5    Venkatachalam, S.6
  • 112
    • 79954613030 scopus 로고    scopus 로고
    • Genetic and expressional alterations of CHD genes in gastric and colorectal cancers
    • Kim MS, Chung NG, Kang MR, Yoo NJ, Lee SH. Genetic and expressional alterations of CHD genes in gastric and colorectal cancers. Histopathology 58(5), 660-668 (2011).
    • (2011) Histopathology , vol.58 , Issue.5 , pp. 660-668
    • Kim, M.S.1    Chung, N.G.2    Kang, M.R.3    Yoo, N.J.4    Lee, S.H.5
  • 113
    • 55849092083 scopus 로고    scopus 로고
    • Mutation and methylation analysis of the chromodomain-helicase-DNA binding 5 gene in ovarian cancer
    • Gorringe KL, Choong DY, Williams LH et al. Mutation and methylation analysis of the chromodomain-helicase-DNA binding 5 gene in ovarian cancer. Neoplasia 10(11), 1253-1258 (2008).
    • (2008) Neoplasia , vol.10 , Issue.11 , pp. 1253-1258
    • Gorringe, K.L.1    Choong, D.Y.2    Williams, L.H.3
  • 115
    • 54949152670 scopus 로고    scopus 로고
    • Chromatin remodeling factor CHD5 is silenced by promoter CpG island hypermethylation in human cancer
    • Mulero-Navarro S, Esteller M. Chromatin remodeling factor CHD5 is silenced by promoter CpG island hypermethylation in human cancer. Epigenetics 3(4), 210-215 (2008).
    • (2008) Epigenetics , vol.3 , Issue.4 , pp. 210-215
    • Mulero-Navarro, S.1    Esteller, M.2
  • 116
    • 77957907502 scopus 로고    scopus 로고
    • Expression of the neuron-specific protein CHD5 is an independent marker of outcome in neuroblastoma
    • Garcia I, Mayol G, Rodriguez E et al. Expression of the neuron-specific protein CHD5 is an independent marker of outcome in neuroblastoma. Mol. Cancer 9, 277 (2010).
    • (2010) Mol. Cancer , vol.9 , pp. 277
    • Garcia, I.1    Mayol, G.2    Rodriguez, E.3
  • 117
    • 80255138705 scopus 로고    scopus 로고
    • CHD5 downregulation associated with poor prognosis in epithelial ovarian cancer
    • Wong RR, Chan LK, Tsang TP et al. CHD5 downregulation associated with poor prognosis in epithelial ovarian cancer. Gynecol. Obstet. Invest. 72(3), 203-207 (2011).
    • (2011) Gynecol. Obstet. Invest , vol.72 , Issue.3 , pp. 203-207
    • Wong, R.R.1    Chan, L.K.2    Tsang, T.P.3
  • 118
    • 84860327480 scopus 로고    scopus 로고
    • Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
    • Zang ZJ, Cutcutache I, Poon SL et al. Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. Nat. Genet. 44(5), 570-574 (2012).
    • (2012) Nat. Genet , vol.44 , Issue.5 , pp. 570-574
    • Zang, Z.J.1    Cutcutache, I.2    Poon, S.L.3
  • 119
    • 84862777348 scopus 로고    scopus 로고
    • Driver mutations in hist one H3.3 and chromatin remodelling genes in paediatric glioblastoma
    • Schwartzentruber J, Korshunov A, Liu XY et al. Driver mutations in hist one H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 482(7384), 226-231 (2012).
    • (2012) Nature , vol.482 , Issue.7384 , pp. 226-231
    • Schwartzentruber, J.1    Korshunov, A.2    Liu, X.Y.3
  • 120
    • 84862777410 scopus 로고    scopus 로고
    • Somatic hist one H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-Brainstem glioblastomas
    • Wu G, Broniscer A, McEachron TA et al. Somatic hist one H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-Brainstem glioblastomas. Nat. Genet. 44(3), 251-253 (2012).
    • (2012) Nat. Genet , vol.44 , Issue.3 , pp. 251-253
    • Wu, G.1    Broniscer, A.2    McEachron, T.A.3
  • 121
    • 21744457108 scopus 로고    scopus 로고
    • Global histone modification patterns predict risk of prostate cancer recurrence
    • DOI 10.1038/nature03672
    • Seligson DB, Horvath S, Shi T et al. Global hist one modification patterns predict risk of prostate cancer recurrence. Nature 435(7046), 1262-1266 (2005). (Pubitemid 40943093)
    • (2005) Nature , vol.435 , Issue.7046 , pp. 1262-1266
    • Seligson, D.B.1    Horvath, S.2    Shi, T.3    Yu, H.4    Tze, S.5    Grunstein, M.6    Kurdistani, S.K.7
  • 124
    • 77957340047 scopus 로고    scopus 로고
    • Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and hist one modifications
    • Zhang C, Li H, Wang Y et al. Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and hist one modifications. J. Hepatol. 53(5), 889-895 (2010).
    • (2010) J. Hepatol , vol.53 , Issue.5 , pp. 889-895
    • Zhang, C.1    Li, H.2    Wang, Y.3


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