-
1
-
-
33847070442
-
The role of chromatin during transcription
-
DOI 10.1016/j.cell.2007.01.015, PII S0092867407001092
-
Li B, Carey M, Workman JL. The role of chromatin during transcription. Cell 128(4), 707-719 (2007). (Pubitemid 46273570)
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 707-719
-
-
Li, B.1
Carey, M.2
Workman, J.L.3
-
2
-
-
84455200582
-
Combinatorial patterning of chromatin regulators uncovered by genome-Wide location analysis in human cells
-
Ram O, Goren A, Amit I et al. Combinatorial patterning of chromatin regulators uncovered by genome-Wide location analysis in human cells. Cell 147(7), 1628-1639 (2011).
-
(2011)
Cell
, vol.147
, Issue.7
, pp. 1628-1639
-
-
Ram, O.1
Goren, A.2
Amit, I.3
-
3
-
-
33644846509
-
Epigenetic gene silencing in cancer - A mechanism for early oncogenic pathway addiction?
-
DOI 10.1038/nrc1799, PII N1799
-
Baylin SB, Ohm JE. Epigenetic gene silencing in cancer - A mechanism for early oncogenic pathway addiction? Nat. Rev. Cancer 6(2), 107-116 (2006). (Pubitemid 43361543)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.2
, pp. 107-116
-
-
Baylin, S.B.1
Ohm, J.E.2
-
4
-
-
79952384705
-
Cancer epigenetics reaches mainstream oncology
-
Rodriguez-Paredes M, Esteller M. Cancer epigenetics reaches mainstream oncology. Nat. Med. 17(3), 330-339 (2011).
-
(2011)
Nat. Med
, vol.17
, Issue.3
, pp. 330-339
-
-
Rodriguez-Paredes, M.1
Esteller, M.2
-
5
-
-
77953995002
-
Covalent hist one modifications - miswritten, misinterpreted and mis-erased in human cancers
-
Chi P, Allis CD, Wang GG. Covalent hist one modifications - miswritten, misinterpreted and mis-erased in human cancers. Nat. Rev. Cancer 10(7), 457-469 (2010).
-
(2010)
Nat. Rev. Cancer
, vol.10
, Issue.7
, pp. 457-469
-
-
Chi, P.1
Allis, C.D.2
Wang, G.G.3
-
6
-
-
78651390167
-
Long intergenic noncoding RNAs: New links in cancer progression
-
Tsai MC, Spitale RC, Chang HY. Long intergenic noncoding RNAs: New links in cancer progression. Cancer Res. 71(1), 3-7 (2011).
-
(2011)
Cancer Res
, vol.71
, Issue.1
, pp. 3-7
-
-
Tsai, M.C.1
Spitale, R.C.2
Chang, H.Y.3
-
7
-
-
33847076849
-
Chromatin modifications and their function
-
DOI 10.1016/j.cell.2007.02.005, PII S0092867407001845
-
Kouzarides T. Chromatin modifications and their function. Cell 128(4), 693-705 (2007). (Pubitemid 46273577)
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 693-705
-
-
Kouzarides, T.1
-
8
-
-
0034610814
-
The language of covalent histone modifications
-
DOI 10.1038/47412
-
Strahl BD, Allis CD. The language of covalent hist one modifications. Nature 403(6765), 41-45 (2000). (Pubitemid 30038513)
-
(2000)
Nature
, vol.403
, Issue.6765
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
9
-
-
78649922622
-
The chromatin signaling pathway: Diverse mechanisms of recruitment of hist one-modifying enzymes and varied biological outcomes
-
Smith E, Shilatifard A. The chromatin signaling pathway: Diverse mechanisms of recruitment of hist one-modifying enzymes and varied biological outcomes. Mol. Cell 40(5), 689-701 (2010).
-
(2010)
Mol. Cell
, vol.40
, Issue.5
, pp. 689-701
-
-
Smith, E.1
Shilatifard, A.2
-
10
-
-
34547890019
-
Functions of site-specific hist one acetylation and deacetylation
-
Shahbazian MD, Grunstein M. Functions of site-specific hist one acetylation and deacetylation. Annu. Rev. Biochem. 76, 75-100 (2007).
-
(2007)
Annu. Rev. Biochem
, vol.76
, pp. 75-100
-
-
Shahbazian, M.D.1
Grunstein, M.2
-
11
-
-
30344477367
-
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
-
DOI 10.1038/nrc1779
-
Minucci S, Pelicci PG. Hist one deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nat. Rev. Cancer 6(1), 38-51 (2006). (Pubitemid 43054973)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.1
, pp. 38-51
-
-
Minucci, S.1
Pelicci, P.G.2
-
12
-
-
0030797585
-
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
-
DOI 10.1016/S0092-8674(00)80521-8
-
Gu W, Roeder RG. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 90(4), 595-606 (1997). (Pubitemid 27357952)
-
(1997)
Cell
, vol.90
, Issue.4
, pp. 595-606
-
-
Gu, W.1
Roeder, R.G.2
-
13
-
-
0035868964
-
P300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2
-
DOI 10.1093/emboj/20.6.1331
-
Ito A, Lai CH, Zhao X et al. p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2. EMBO J. 20(6), 1331-1340 (2001). (Pubitemid 32233973)
-
(2001)
EMBO Journal
, vol.20
, Issue.6
, pp. 1331-1340
-
-
Ito, A.1
Lai, C.-H.2
Zhao, X.3
Saito, S.4
Hamilton, M.H.5
Appella, E.6
Yao, T.-P.7
-
14
-
-
50149109481
-
Epigenetic reprogramming by adenovirus e1a
-
Ferrari R, Pellegrini M, Horwitz GA, Xie W, Berk AJ, Kurdistani SK. Epigenetic reprogramming by adenovirus e1a. Science 321(5892), 1086-1088 (2008).
-
(2008)
Science
, vol.321
, Issue.5892
, pp. 1086-1088
-
-
Ferrari, R.1
Pellegrini, M.2
Horwitz, G.A.3
Xie, W.4
Berk, A.J.5
Kurdistani, S.K.6
-
15
-
-
0034104047
-
Mutations truncating the EP300 acetylase in human cancers
-
DOI 10.1038/73536
-
Gayther SA, Batley SJ, Linger L et al. Mutations truncating the EP300 acetylase in human cancers. Nat. Genet. 24(3), 300-303 (2000). (Pubitemid 30132203)
-
(2000)
Nature Genetics
, vol.24
, Issue.3
, pp. 300-303
-
-
Gayther, S.A.1
Batley, S.J.2
Linger, L.3
Bannister, A.4
Thorpe, K.5
Chin, S.-F.6
Daigo, Y.7
Russell, P.8
Wilson, A.9
Sowter, H.M.10
Delhanty, J.D.A.11
Ponder, B.A.J.12
Kouzarides, T.13
Caldas, C.14
-
16
-
-
0029940574
-
P300 gene alterations in colorectal and gastric carcinomas
-
Muraoka M, Konishi M, Kikuchi-Yanoshita R et al. p300 gene alterations in colorectal and gastric carcinomas. Oncogene 12(7), 1565-1569 (1996). (Pubitemid 26132043)
-
(1996)
Oncogene
, vol.12
, Issue.7
, pp. 1565-1569
-
-
Muraoka, M.1
Konishi, M.2
Kikuchi-Yanoshita, R.3
Tanaka, K.4
Shitara, N.5
Chong, J.-M.6
Iwama, T.7
Miyaki, M.8
-
17
-
-
0029022770
-
Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP
-
Petrij F, Giles RH, Dauwerse HG et al. Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP. Nature 376(6538), 348-351 (1995).
-
(1995)
Nature
, vol.376
, Issue.6538
, pp. 348-351
-
-
Petrij, F.1
Giles, R.H.2
Dauwerse, H.G.3
-
18
-
-
9544220768
-
The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-Binding protein
-
Borrow J, Stanton VP Jr, Andresen JM et al. The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-Binding protein. Nat. Genet. 14(1), 33-41 (1996).
-
(1996)
Nat. Genet
, vol.14
, Issue.1
, pp. 33-41
-
-
Borrow, J.1
Stanton Jr., V.P.2
Andresen, J.M.3
-
19
-
-
0344441910
-
PCAF is a coactivator for p73-mediated transactivation
-
DOI 10.1038/sj.onc.1206916
-
Zhao LY, Liu Y, Bertos NR, Yang XJ, Liao D. PCAF is a coactivator for p73-mediated transactivation. Oncogene 22(51), 8316-8329 (2003). (Pubitemid 37485524)
-
(2003)
Oncogene
, vol.22
, Issue.51
, pp. 8316-8329
-
-
Zhao, L.Y.1
Liu, Y.2
Bertos, N.R.3
Yang, X.-J.4
Liao, D.5
-
20
-
-
68349125550
-
Characterization of tumor suppressive function of P300/ CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma
-
Zhu C, Qin YR, Xie D et al. Characterization of tumor suppressive function of P300/ CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma. Oncogene 28(31), 2821-2828 (2009).
-
(2009)
Oncogene
, vol.28
, Issue.31
, pp. 2821-2828
-
-
Zhu, C.1
Qin, Y.R.2
Xie, D.3
-
21
-
-
18744391052
-
Mutation analysis of CBP and PCAF reveals rare inactivating mutations in cancer cell lines but not in primary tumours
-
DOI 10.1038/sj.bjc.6600554
-
Ozdag H, Batley SJ, Forsti A et al. Mutation analysis of CBP and PCAF reveals rare inactivating mutations in cancer cell lines but not in primary tumours. Br. J. Cancer 87(10), 1162-1165 (2002). (Pubitemid 35422720)
-
(2002)
British Journal of Cancer
, vol.87
, Issue.10
, pp. 1162-1165
-
-
Ozdag, H.1
Batley, S.J.2
Forsti, A.3
Iyer, N.G.4
Daigo, Y.5
Boutell, J.6
Arends, M.J.7
Ponder, B.A.J.8
Kouzarides, T.9
Caldas, C.10
-
22
-
-
1842631408
-
Upregulation and nuclear recruitment of HDACl in hormone refractory prostate cancer
-
DOI 10.1002/pros.20022
-
Halkidou K, Gaughan L, Cook S, Leung HY, Neal DE, Robson CN. Upregulation and nuclear recruitment of HDAC1 in hormOne refractory prostate cancer. Prostate 59(2), 177-189 (2004). (Pubitemid 38481229)
-
(2004)
Prostate
, vol.59
, Issue.2
, pp. 177-189
-
-
Halkidou, K.1
Gaughan, L.2
Cook, S.3
Leung, H.Y.4
Neal, D.E.5
Robson, C.N.6
-
23
-
-
33744956666
-
Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer
-
DOI 10.1074/jbc.M510023200
-
Wilson AJ, Byun DS, Popova N et al. Hist one deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer. J. Biol. Chem. 281(19), 13548-13558 (2006). (Pubitemid 43855268)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.19
, pp. 13548-13558
-
-
Wilson, A.J.1
Byun, D.-S.2
Popova, N.3
Murray, L.B.4
L'Italien, K.5
Sowa, Y.6
Arango, D.7
Velcich, A.8
Augenlicht, L.H.9
Mariadason, J.M.10
-
24
-
-
33748451151
-
Anticancer activities of histone deacetylase inhibitors
-
DOI 10.1038/nrd2133, PII NRD2133
-
Bolden JE, Peart MJ, JohnstOne RW. Anticancer activities of hist one deacetylase inhibitors. Nat. Rev. Drug Discov. 5(9), 769-784 (2006). (Pubitemid 44348499)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.9
, pp. 769-784
-
-
Bolden, J.E.1
Peart, M.J.2
Johnstone, R.W.3
-
25
-
-
33646354640
-
A truncating mutation of HDAC2 in human cancers confers resistance to hist one deacetylase inhibition
-
Ropero S, Fraga MF, Ballestar E et al. A truncating mutation of HDAC2 in human cancers confers resistance to hist one deacetylase inhibition. Nat. Genet. 38(5), 566-569 (2006).
-
(2006)
Nat. Genet
, vol.38
, Issue.5
, pp. 566-569
-
-
Ropero, S.1
Fraga, M.F.2
Ballestar, E.3
-
26
-
-
2942722811
-
Molecular mechanisms of E2F-dependent activation and pRB-mediated repression
-
DOI 10.1242/jcs.01227
-
Frolov MV, Dyson NJ. Molecular mechanisms of E2F-dependent activation and pRB-mediated repression. J. Cell. Sci. 117(PT11), 2173-2181 (2004). (Pubitemid 38807486)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.11
, pp. 2173-2181
-
-
Frolov, M.V.1
Dyson, N.J.2
-
27
-
-
77957266345
-
Aging and cancer: Are sirtuins the link
-
Rodriguez RM, Fraga MF. Aging and cancer: Are sirtuins the link? Future Oncol. 6(6), 905-915 (2010).
-
(2010)
Future Oncol
, vol.6
, Issue.6
, pp. 905-915
-
-
Rodriguez, R.M.1
Fraga, M.F.2
-
28
-
-
34547875773
-
Sirtuins: Critical regulators at the crossroads between cancer and aging
-
DOI 10.1038/sj.onc.1210616, PII 1210616
-
Saunders LR, Verdin E. Sirtuins: Critical regulators at the crossroads between cancer and aging. Oncogene 26(37), 5489-5504 (2007). (Pubitemid 47255930)
-
(2007)
Oncogene
, vol.26
, Issue.37
, pp. 5489-5504
-
-
Saunders, L.R.1
Verdin, E.2
-
29
-
-
53149137486
-
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
-
Wang RH, Sengupta K, Li C et al. Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell 14(4), 312-323 (2008).
-
(2008)
Cancer Cell
, vol.14
, Issue.4
, pp. 312-323
-
-
Wang, R.H.1
Sengupta, K.2
Li, C.3
-
30
-
-
79551521179
-
Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation
-
Powell MJ, Casimiro MC, Cordon-Cardo C et al. Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation. Cancer Res. 71(3), 964-975 (2010).
-
(2010)
Cancer Res
, vol.71
, Issue.3
, pp. 964-975
-
-
Powell, M.J.1
Casimiro, M.C.2
Cordon-Cardo, C.3
-
31
-
-
80054769188
-
SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity
-
Kim HS, Vassilopoulos A, Wang RH et al. SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity. Cancer Cell 20(4), 487-499 (2011).
-
(2011)
Cancer Cell
, vol.20
, Issue.4
, pp. 487-499
-
-
Kim, H.S.1
Vassilopoulos, A.2
Wang, R.H.3
-
32
-
-
79952501323
-
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
-
Finley LW, Carracedo A, Lee J et al. SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization. Cancer Cell 19(3), 416-428 (2011).
-
(2011)
Cancer Cell
, vol.19
, Issue.3
, pp. 416-428
-
-
Finley, L.W.1
Carracedo, A.2
Lee, J.3
-
33
-
-
76049100577
-
HIF-1: Upstream and downstream of cancer metabolism
-
Semenza GL. HIF-1: Upstream and downstream of cancer metabolism. Curr. Opin. Genet. Dev. 20(1), 51-56 (2010).
-
(2010)
Curr. Opin. Genet. Dev
, vol.20
, Issue.1
, pp. 51-56
-
-
Semenza, G.L.1
-
34
-
-
74049094817
-
SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
-
Kim HS, Patel K, Muldoon-Jacobs K et al. SIRT3 is a mitochondria- localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. Cancer Cell 17(1), 41-52 (2010).
-
(2010)
Cancer Cell
, vol.17
, Issue.1
, pp. 41-52
-
-
Kim, H.S.1
Patel, K.2
Muldoon-Jacobs, K.3
-
35
-
-
77953644347
-
Reversal of hist one methylation: Biochemical and molecular mechanisms of hist one demethylases
-
Mosammaparast N, Shi Y. Reversal of hist one methylation: Biochemical and molecular mechanisms of hist one demethylases. Annu. Rev. Biochem. 79, 155-179 (2010).
-
(2010)
Annu. Rev. Biochem
, vol.79
, pp. 155-179
-
-
Mosammaparast, N.1
Shi, Y.2
-
36
-
-
78751590899
-
Silencing chromatin: Comparing modes and mechanisms
-
Beisel C, Paro R. Silencing chromatin: Comparing modes and mechanisms. Nat. Rev. Genet. 12(2), 123-135 (2011).
-
(2011)
Nat. Rev. Genet
, vol.12
, Issue.2
, pp. 123-135
-
-
Beisel, C.1
Paro, R.2
-
37
-
-
0032188763
-
2-M cell cycle arrest and/or apoptosis
-
He L, Yu JX, Liu L et al. RIZ1, but not the alternative RIZ2 product of the same gene, is underexpressed in breast cancer, and forced RIZ1 expression causes G2-M cell cycle arrest and/or apoptosis. Cancer Res. 58(19), 4238-4244 (1998). (Pubitemid 28450017)
-
(1998)
Cancer Research
, vol.58
, Issue.19
, pp. 4238-4244
-
-
He, L.1
Yu, J.X.2
Liu, L.3
Buyse, I.M.4
Wang, M.-S.5
Yang, Q.-C.6
Nakagawara, A.7
Brodeur, G.M.8
Shi, Y.E.9
Huang, S.10
-
38
-
-
0345275880
-
Inactivation of a Histone Methyltransferase by Mutations in Human Cancers
-
Kim KC, Geng L, Huang S. Inactivation of a hist one methyltransferase by mutations in human cancers. Cancer Res. 63(22), 7619-7623 (2003). (Pubitemid 37466684)
-
(2003)
Cancer Research
, vol.63
, Issue.22
, pp. 7619-7623
-
-
Kim, K.-C.1
Geng, L.2
Huang, S.3
-
39
-
-
0035890771
-
Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily
-
Du Y, Carling T, Fang W, Piao Z, Sheu JC, Huang S. Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a hist one/protein methyltransferase superfamily. Cancer Res. 61(22), 8094-8099 (2001). (Pubitemid 33091596)
-
(2001)
Cancer Research
, vol.61
, Issue.22
, pp. 8094-8099
-
-
Du, Y.1
Carling, T.2
Fang, W.3
Piao, Z.4
Sheu, J.-C.5
Huang, S.6
-
40
-
-
2342564968
-
Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma
-
DOI 10.1002/ijc.20090
-
Oshimo Y, Oue N, Mitani Y et al. Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma. Int. J. Cancer 110(2), 212-218 (2004). (Pubitemid 38580393)
-
(2004)
International Journal of Cancer
, vol.110
, Issue.2
, pp. 212-218
-
-
Oshimo, Y.1
Oue, N.2
Mitani, Y.3
Nakayama, H.4
Kitadai, Y.5
Yoshida, K.6
Chayama, K.7
Yasui, W.8
-
41
-
-
46849115153
-
Hist one methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes
-
Xie P, Tian C, An L et al. Hist one methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes. Cell Signal 20(9), 1671-1678 (2008).
-
(2008)
Cell Signal
, vol.20
, Issue.9
, pp. 1671-1678
-
-
Xie, P.1
Tian, C.2
An, L.3
-
42
-
-
9244247669
-
Regulation of p53 activity through lysine methylation
-
DOI 10.1038/nature03117
-
Chuikov S, Kurash JK, Wilson JR et al. Regulation of p53 activity through lysine methylation. Nature 432(7015), 353-360 (2004). (Pubitemid 39551664)
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 353-360
-
-
Chuikov, S.1
Kurash, J.K.2
Wilson, J.R.3
Xiao, B.4
Justin, N.5
Ivanov, G.S.6
McKinney, K.7
Tempst, P.8
Prives, C.9
Gamblin, S.J.10
Barlev, N.A.11
Reinberg, D.12
-
43
-
-
80051733367
-
P53-dependent transcription and tumor suppression are not affected in Set7/9-deficient mice
-
Lehnertz B, Rogalski JC, Schulze FM et al. p53-dependent transcription and tumor suppression are not affected in Set7/9-deficient mice. Mol. Cell 43(4), 673-680 (2011).
-
(2011)
Mol. Cell
, vol.43
, Issue.4
, pp. 673-680
-
-
Lehnertz, B.1
Rogalski, J.C.2
Schulze, F.M.3
-
44
-
-
70049111751
-
The mRNA expression of SETD2 in human breast cancer: Correlation with clinico-Pathological parameters
-
Al Sarakbi W, Sasi W, Jiang WG, Roberts T, Newbold RF, Mokbel K. The mRNA expression of SETD2 in human breast cancer: Correlation with clinico-Pathological parameters. BMC Cancer 9, 290 (2009).
-
(2009)
BMC Cancer
, vol.9
, pp. 290
-
-
Al Sarakbi, W.1
Sasi, W.2
Jiang, W.G.3
Roberts, T.4
Newbold, R.F.5
Mokbel, K.6
-
45
-
-
75149188170
-
Systematic sequencing of renal carcinoma reveals inactivation of hist one modifying genes
-
Dalgliesh GL, Furge K, Greenman C et al. Systematic sequencing of renal carcinoma reveals inactivation of hist one modifying genes. Nature 463(7279), 360-363 (2010).
-
(2010)
Nature
, vol.463
, Issue.7279
, pp. 360-363
-
-
Dalgliesh, G.L.1
Furge, K.2
Greenman, C.3
-
46
-
-
77953170322
-
Hist one methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma
-
Duns G, van den Berg E, van Duivenbode I et al. Hist one methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma. Cancer Res. 70(11), 4287-4291 (2010).
-
(2010)
Cancer Res
, vol.70
, Issue.11
, pp. 4287-4291
-
-
Duns, G.1
Van Den Berg, E.2
Van Duivenbode, I.3
-
47
-
-
84862907593
-
The genetic basis of early T-Cell precursor acute lymphoblastic leukaemia
-
Zhang J, Ding L, Holmfeldt L et al. The genetic basis of early T-Cell precursor acute lymphoblastic leukaemia. Nature 481(7380), 157-163 (2012).
-
(2012)
Nature
, vol.481
, Issue.7380
, pp. 157-163
-
-
Zhang, J.1
Ding, L.2
Holmfeldt, L.3
-
48
-
-
79959272481
-
Cancers and the NSD family of hist one lysine methyltransferases
-
Morishita M, di Luccio E. Cancers and the NSD family of hist one lysine methyltransferases. Biochim. Biophys. Acta 1816(2), 158-163 (2011).
-
(2011)
Biochim. Biophys. Acta
, vol.1816
, Issue.2
, pp. 158-163
-
-
Morishita, M.1
Di Luccio, E.2
-
49
-
-
42449161943
-
The MMSET protein is a hist one methyltransferase with characteristics of a transcriptional corepressor
-
Marango J, Shimoyama M, Nishio H et al. The MMSET protein is a hist one methyltransferase with characteristics of a transcriptional corepressor. Blood 111(6), 3145-3154 (2008).
-
(2008)
Blood
, vol.111
, Issue.6
, pp. 3145-3154
-
-
Marango, J.1
Shimoyama, M.2
Nishio, H.3
-
50
-
-
76049084596
-
Epigenetic inactivation of the Sotos overgrowth syndrome gene hist one methyltransferase NSD1 in human neuroblastoma and glioma
-
Berdasco M, Ropero S, Setien F et al. Epigenetic inactivation of the Sotos overgrowth syndrome gene hist one methyltransferase NSD1 in human neuroblastoma and glioma. Proc. Natl Acad. Sci. USA 106(51), 21830-21835 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, Issue.51
, pp. 21830-21835
-
-
Berdasco, M.1
Ropero, S.2
Setien, F.3
-
51
-
-
33847049891
-
The histone methyltransferase activity of WHISTLE is important for the induction of apoptosis and HDAC1-mediated transcriptional repression
-
DOI 10.1016/j.yexcr.2006.12.007, PII S0014482706005180
-
Kim SM, Kee HJ, Choe N, Kim JY, Kook H, Seo SB. The hist one methyltransferase activity of WHISTLE is important for the induction of apoptosis and HDAC1- mediated transcriptional repression. Exp. Cell Res. 313(5), 975-983 (2007). (Pubitemid 46273444)
-
(2007)
Experimental Cell Research
, vol.313
, Issue.5
, pp. 975-983
-
-
Kim, S.-M.1
Kee, H.-J.2
Choe, N.3
Kim, J.-Y.4
Kook, H.5
Kook, H.6
Seo, S.-B.7
-
52
-
-
77955268518
-
The NSD3L hist one methyltransferase regulates cell cycle and cell invasion in breast cancer cells
-
Zhou Z, Thomsen R, Kahns S, Nielsen AL. The NSD3L hist one methyltransferase regulates cell cycle and cell invasion in breast cancer cells. Biochem. Biophys. Res. Commun. 398(3), 565-570 (2010).
-
(2010)
Biochem. Biophys. Res. Commun
, vol.398
, Issue.3
, pp. 565-570
-
-
Zhou, Z.1
Thomsen, R.2
Kahns, S.3
Nielsen, A.L.4
-
53
-
-
35349006314
-
Histone lysine demethylases: Emerging roles in development, physiology and disease
-
DOI 10.1038/nrg2218, PII NRG2218
-
Shi Y. Hist one lysine demethylases: Emerging roles in development, physiology and disease. Nat. Rev. Genet. 8(11), 829-833 (2007). (Pubitemid 47609092)
-
(2007)
Nature Reviews Genetics
, vol.8
, Issue.11
, pp. 829-833
-
-
Shi, Y.1
-
54
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
DOI 10.1016/j.cell.2004.12.012, PII S0092867404011997
-
Shi Y, Lan F, Matson C et al. Hist one demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119(7), 941-953 (2004). (Pubitemid 40037608)
-
(2004)
Cell
, vol.119
, Issue.7
, pp. 941-953
-
-
Shi, Y.1
Lan, F.2
Matson, C.3
Mulligan, P.4
Whetstine, J.R.5
Cole, P.A.6
Casero, R.A.7
Shi, Y.8
-
55
-
-
68749108259
-
LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer
-
Wang Y, Zhang H, Chen Y et al. LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer. Cell 138(4), 660-672 (2009).
-
(2009)
Cell
, vol.138
, Issue.4
, pp. 660-672
-
-
Wang, Y.1
Zhang, H.2
Chen, Y.3
-
56
-
-
78649815150
-
Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers
-
Hayami S, Kelly JD, Cho HS et al. Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers. Int. J. Cancer 128(3), 574-586 (2010).
-
(2010)
Int. J. Cancer
, vol.128
, Issue.3
, pp. 574-586
-
-
Hayami, S.1
Kelly, J.D.2
Cho, H.S.3
-
57
-
-
34548513035
-
P53 is regulated by the lysine demethylase LSD1
-
DOI 10.1038/nature06092, PII NATURE06092
-
Huang J, Sengupta R, Espejo AB et al. p53 is regulated by the lysine demethylase LSD1. Nature 449(7158), 105-108 (2007). (Pubitemid 47373772)
-
(2007)
Nature
, vol.449
, Issue.7158
, pp. 105-108
-
-
Huang, J.1
Sengupta, R.2
Espejo, A.B.3
Lee, M.G.4
Dorsey, J.A.5
Richter, M.6
Opravil, S.7
Shiekhattar, R.8
Bedford, M.T.9
Jenuwein, T.10
Berger, S.L.11
-
58
-
-
84862123313
-
The hist one demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells
-
Harris WJ, Huang X, Lynch JT et al. The hist one demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells. Cancer Cell 21(4), 473-487 (2012).
-
(2012)
Cancer Cell
, vol.21
, Issue.4
, pp. 473-487
-
-
Harris, W.J.1
Huang, X.2
Lynch, J.T.3
-
59
-
-
36749082438
-
Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases
-
DOI 10.1073/pnas.0707292104
-
Hong S, Cho YW, Yu LR, Yu H, Veenstra TD, Ge K. Identification of JmjC domain-Containing UTX and JMJD3 as hist one H3 lysine 27 demethylases. Proc. Natl Acad. Sci. USA 104(47), 18439-18444 (2007). (Pubitemid 350210715)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.47
, pp. 18439-18444
-
-
Hong, S.1
Cho, Y.-W.2
Yu, L.-R.3
Yu, H.4
Veenstra, T.D.5
Ge, K.6
-
60
-
-
67349203626
-
Somatic mutations of the hist one H3K27 demethylase gene UTX in human cancer
-
van Haaften G, Dalgliesh GL, Davies H et al. Somatic mutations of the hist one H3K27 demethylase gene UTX in human cancer. Nat. Genet. 41(5), 521-523 (2009).
-
(2009)
Nat. Genet
, vol.41
, Issue.5
, pp. 521-523
-
-
Van Haaften, G.1
Dalgliesh, G.L.2
Davies, H.3
-
61
-
-
77951980558
-
The H3K27me3 demethylase dUTX is a suppressor of Notch- And Rb-dependent tumors in Drosophila
-
Herz HM, Madden LD, Chen Z et al. The H3K27me3 demethylase dUTX is a suppressor of Notch- And Rb-dependent tumors in Drosophila. Mol. Cell. Biol. 30(10), 2485-2497 (2010).
-
(2010)
Mol. Cell. Biol
, vol.30
, Issue.10
, pp. 2485-2497
-
-
Herz, H.M.1
Madden, L.D.2
Chen, Z.3
-
62
-
-
76749139057
-
The hist one demethylase UTX enables RB-dependent cell fate control
-
Wang JK, Tsai MC, Poulin G et al. The hist one demethylase UTX enables RB-dependent cell fate control. Genes Dev. 24(4), 327-332 (2010).
-
(2010)
Genes Dev
, vol.24
, Issue.4
, pp. 327-332
-
-
Wang, J.K.1
Tsai, M.C.2
Poulin, G.3
-
63
-
-
66149138053
-
The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene-and stress-induced senescence
-
Agger K, Cloos PA, Rudkjaer L et al. The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene-and stress-induced senescence. Genes Dev. 23(10), 1171-1176 (2009).
-
(2009)
Genes Dev
, vol.23
, Issue.10
, pp. 1171-1176
-
-
Agger, K.1
Cloos, P.A.2
Rudkjaer, L.3
-
64
-
-
84856955226
-
The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through hist one demethylase JARID1C
-
Niu X, Zhang T, Liao L et al. The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through hist one demethylase JARID1C. Oncogene 31(6), 776-786 (2011).
-
(2011)
Oncogene
, vol.31
, Issue.6
, pp. 776-786
-
-
Niu, X.1
Zhang, T.2
Liao, L.3
-
65
-
-
84862966741
-
Increased expression of hist one demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-Regulating angiogenesis
-
Osawa T, Muramatsu M, Wang F et al. Increased expression of hist one demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-Regulating angiogenesis. Proc. Natl Acad. Sci. USA 108(51), 20725-20729 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, Issue.51
, pp. 20725-20729
-
-
Osawa, T.1
Muramatsu, M.2
Wang, F.3
-
66
-
-
80155131102
-
Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14
-
Li Q, Shi L, Gui B et al. Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14. Cancer Res. 71(21), 6899-6908 (2011).
-
(2011)
Cancer Res
, vol.71
, Issue.21
, pp. 6899-6908
-
-
Li, Q.1
Shi, L.2
Gui, B.3
-
67
-
-
80053203114
-
The hist one demethylase Jarid1b (Kdm5b) is a novel compOnent of the Rb pathway and associates with E2f-target genes in MEFs during senescence
-
Nijwening JH, Geutjes EJ, Bernards R, Beijersbergen RL. The hist one demethylase Jarid1b (Kdm5b) is a novel compOnent of the Rb pathway and associates with E2f-target genes in MEFs during senescence. Plos One 6(9), e25235 (2011).
-
(2011)
Plos One
, vol.6
, Issue.9
-
-
Nijwening, J.H.1
Geutjes, E.J.2
Bernards, R.3
Beijersbergen, R.L.4
-
68
-
-
75749101495
-
Chromatin remodelling during development
-
Ho L, Crabtree GR. Chromatin remodelling during development. Nature 463(7280), 474-484 (2010).
-
(2010)
Nature
, vol.463
, Issue.7280
, pp. 474-484
-
-
Ho, L.1
Crabtree, G.R.2
-
69
-
-
1042290351
-
The SWI/SNF complex - Chromatin and cancer
-
Roberts CW, Orkin SH. The SWI/SNF complex - chromatin and cancer. Nat. Rev. Cancer 4(2), 133-142 (2004). (Pubitemid 38198741)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.2
, pp. 133-142
-
-
Roberts, C.W.M.1
Orkin, S.H.2
-
70
-
-
79959653996
-
SWI/SNF nucleosome remodellers and cancer
-
Wilson BG, Roberts CW. SWI/SNF nucleosome remodellers and cancer. Nat. Rev. Cancer 11(7), 481-492 (2011).
-
(2011)
Nat. Rev. Cancer
, vol.11
, Issue.7
, pp. 481-492
-
-
Wilson, B.G.1
Roberts, C.W.2
-
71
-
-
2642647094
-
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
-
DOI 10.1038/28212
-
Versteege I, Sevenet N, Lange J et al. Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer. Nature 394(6689), 203-206 (1998). (Pubitemid 28325977)
-
(1998)
Nature
, vol.394
, Issue.6689
, pp. 203-206
-
-
Versteege, I.1
Sevenet, N.2
Lange, J.3
Rousseau-Merck, M.-F.4
Ambros, P.5
Handgretinger, R.6
Aurias, A.7
Delattre, O.8
-
72
-
-
2042432488
-
Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers
-
DOI 10.1086/302639
-
Sevenet N, Sheridan E, Amram D, Schneider P, Handgretinger R, Delattre O. Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers. Am. J. Hum. Genet. 65(5), 1342-1348 (1999). (Pubitemid 30460384)
-
(1999)
American Journal of Human Genetics
, vol.65
, Issue.5
, pp. 1342-1348
-
-
Sevenet, N.1
Sheridan, E.2
Amram, D.3
Schneider, P.4
Handgretinger, R.5
Delattre, O.6
-
73
-
-
0034610395
-
Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice
-
Roberts CW, Galusha SA, McMenamin ME, Fletcher CD, Orkin SH. Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice. Proc. Natl Acad. Sci. USA 97(25), 13796-13800 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, Issue.25
, pp. 13796-13800
-
-
Roberts, C.W.1
Galusha, S.A.2
McMenamin, M.E.3
Fletcher, C.D.4
Orkin, S.H.5
-
74
-
-
0042452295
-
Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5
-
DOI 10.1016/S1535-6108(02)00185-X
-
Roberts CW, Leroux MM, Fleming MD, Orkin SH. Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5. Cancer Cell 2(5), 415-425 (2002). (Pubitemid 41039107)
-
(2002)
Cancer Cell
, vol.2
, Issue.5
, pp. 415-425
-
-
Roberts, C.W.M.1
Leroux, M.M.2
Fleming, M.D.3
Orkin, S.H.4
-
75
-
-
0036315846
-
Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5
-
DOI 10.1128/MCB.22.16.5975-5988.2002
-
Zhang ZK, Davies KP, Allen J et al. Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5. Mol. Cell. Biol. 22(16), 5975-5988 (2002). (Pubitemid 34815844)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.16
, pp. 5975-5988
-
-
Zhang, Z.-K.1
Davies, K.P.2
Allen, J.3
Zhu, L.4
Pestell, R.G.5
Zagzag, D.6
Kalpana, G.V.7
-
76
-
-
29144453238
-
Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation
-
DOI 10.1073/pnas.0509014102
-
Isakoff MS, Sansam CG, Tamayo P et al. Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation. Proc. Natl Acad. Sci. USA 102(49), 17745-17750 (2005). (Pubitemid 41803568)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.49
, pp. 17745-17750
-
-
Isakoff, M.S.1
Sansam, C.G.2
Tamayo, P.3
Subramanian, A.4
Evans, J.A.5
Fillmore, C.M.6
Wang, X.7
Biegel, J.A.8
Pomeroy, S.L.9
Mesirov, J.P.10
Roberts, C.W.M.11
-
77
-
-
77957955244
-
Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation
-
Wilson BG, Wang X, Shen X et al. Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation. Cancer Cell 18(4), 316-328 (2010).
-
(2010)
Cancer Cell
, vol.18
, Issue.4
, pp. 316-328
-
-
Wilson, B.G.1
Wang, X.2
Shen, X.3
-
78
-
-
53549095222
-
Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability
-
McKenna ES, Sansam CG, Cho YJ et al. Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability. Mol. Cell. Biol. 28(20), 6223-6233 (2008).
-
(2008)
Mol. Cell. Biol
, vol.28
, Issue.20
, pp. 6223-6233
-
-
McKenna, E.S.1
Sansam, C.G.2
Cho, Y.J.3
-
79
-
-
24644470558
-
The Brm gene suppressed at the post-transcriptional level in various human cell lines is inducible by transient HDAC inhibitor treatment, which exhibits antioncogenic potential
-
DOI 10.1038/sj.onc.1208716, PII 1208716
-
Yamamichi N, Yamamichi-Nishina M, Mizutani T et al. The Brm gene suppressed at the post-transcriptional level in various human cell lines is inducible by transient HDAC inhibitor treatment, which exhibits antioncogenic potential. Oncogene 24(35), 5471-5481 (2005). (Pubitemid 43080090)
-
(2005)
Oncogene
, vol.24
, Issue.35
, pp. 5471-5481
-
-
Yamamichi, N.1
Yamamichi-Nishina, M.2
Mizutani, T.3
Watanabe, H.4
Minoguchi, S.5
Kobayashi, N.6
Kimura, S.7
Ito, T.8
Yahagi, N.9
Ichinose, M.10
Omata, M.11
Iba, H.12
-
80
-
-
0034326257
-
BRG1, a compOnent of the SWI-SNF complex, is mutated in multiple human tumor cell lines
-
Wong AK, Shanahan F, Chen Y et al. BRG1, a compOnent of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res. 60(21), 6171-6177 (2000).
-
(2000)
Cancer Res
, vol.60
, Issue.21
, pp. 6171-6177
-
-
Wong, A.K.1
Shanahan, F.2
Chen, Y.3
-
81
-
-
79551572835
-
Massive parallel DNA pyrosequencing analysis of the tumor suppressor BRG1/SMARCA4 in lung primary tumors
-
Rodriguez-Nieto S, Canada A, Pros E et al. Massive parallel DNA pyrosequencing analysis of the tumor suppressor BRG1/SMARCA4 in lung primary tumors. Hum. Mutat. 32(2), e1999-e2017 (2011).
-
(2011)
Hum. Mutat
, vol.32
, Issue.2
-
-
Rodriguez-Nieto, S.1
Canada, A.2
Pros, E.3
-
82
-
-
79957603182
-
BRM and BRG1 subunits of the SWI/SNF chromatin remodelling complex are downregulated upon progression of benign skin lesions into invasive tumours
-
Bock VL, Lyons JG, Huang XX et al. BRM and BRG1 subunits of the SWI/SNF chromatin remodelling complex are downregulated upon progression of benign skin lesions into invasive tumours. Br. J. Dermatol. 164(6), 1221-1227 (2011).
-
(2011)
Br. J. Dermatol
, vol.164
, Issue.6
, pp. 1221-1227
-
-
Bock, V.L.1
Lyons, J.G.2
Huang, X.X.3
-
83
-
-
57749113070
-
The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer
-
Shen H, Powers N, Saini N et al. The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer. Cancer Res. 68(24), 10154-10162 (2008).
-
(2008)
Cancer Res
, vol.68
, Issue.24
, pp. 10154-10162
-
-
Shen, H.1
Powers, N.2
Saini, N.3
-
84
-
-
77957801917
-
The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB-P53 pathways
-
Alessio N, Squillaro T, Cipollaro M, Bagella L, Giordano A, Galderisi U. The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB-P53 pathways. Oncogene 29(40), 5452-5463 (2010).
-
(2010)
Oncogene
, vol.29
, Issue.40
, pp. 5452-5463
-
-
Alessio, N.1
Squillaro, T.2
Cipollaro, M.3
Bagella, L.4
Giordano, A.5
Galderisi, U.6
-
85
-
-
0028060515
-
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest
-
DOI 10.1016/0092-8674(94)90405-7
-
Dunaief JL, Strober BE, Guha S et al. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell 79(1), 119-130 (1994). (Pubitemid 24309518)
-
(1994)
Cell
, vol.79
, Issue.1
, pp. 119-130
-
-
Dunaief, J.L.1
Strober, B.E.2
Guha, S.3
Khavari, P.A.4
Alin, K.5
Luban, J.6
Begemann, M.7
Crabtree, G.R.8
Goff, S.P.9
-
86
-
-
0037085292
-
Compensation of BRG-1 function by Brm. Insight into the role of the core SWI·SNF subunits in retinoblastoma tumor suppressor signaling
-
DOI 10.1074/jbc.M109532200
-
Strobeck MW, Reisman DN, Gunawardena RW et al. Compensation of BRG-1 function by Brm: Insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling. J. Biol. Chem. 277(7), 4782-4789 (2002). (Pubitemid 34968511)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.7
, pp. 4782-4789
-
-
Strobeck, M.W.1
Reisman, D.N.2
Gunawardena, R.W.3
Betz, B.L.4
Angus, S.P.5
Knudsen, K.E.6
Kowalik, T.F.7
Weissman, B.E.8
Knudsen, E.S.9
-
87
-
-
61349129513
-
The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a
-
Becker TM, Haferkamp S, Dijkstra MK et al. The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a. Mol. Cancer 8, 4 (2009).
-
(2009)
Mol. Cancer
, vol.8
, pp. 4
-
-
Becker, T.M.1
Haferkamp, S.2
Dijkstra, M.K.3
-
88
-
-
0034608823
-
BRG-1 is required for RB-mediated cell cycle arrest
-
DOI 10.1073/pnas.97.14.7748
-
Strobeck MW, Knudsen KE, Fribourg AF et al. BRG-1 is required for RB-mediated cell cycle arrest. Proc. Natl Acad. Sci. USA 97(14), 7748-7753 (2000). (Pubitemid 30460719)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.14
, pp. 7748-7753
-
-
Strobeck, M.W.1
Knudsen, K.E.2
Fribourg, A.F.3
DeCristofaro, M.F.4
Weissman, B.E.5
Imbalzano, A.N.6
Knudsen, E.S.7
-
89
-
-
38349010480
-
Characterization of mammary tumors from Brg1 heterozygous mice
-
Bultman SJ, Herschkowitz JI, Godfrey V et al. Characterization of mammary tumors from Brg1 heterozygous mice. Oncogene 27(4), 460-468 (2008).
-
(2008)
Oncogene
, vol.27
, Issue.4
, pp. 460-468
-
-
Bultman, S.J.1
Herschkowitz, J.I.2
Godfrey, V.3
-
90
-
-
34250360362
-
Genomic and functional evidence for an ARID1A tumor suppressor role
-
DOI 10.1002/gcc.20459
-
Huang J, Zhao YL, Li Y, Fletcher JA, Xiao S. Genomic and functional evidence for an ARID1A tumor suppressor role. Genes Chromosomes Cancer 46(8), 745-750 (2007). (Pubitemid 46912345)
-
(2007)
Genes Chromosomes and Cancer
, vol.46
, Issue.8
, pp. 745-750
-
-
Huang, J.1
Zhao, Y.-L.2
Li, Y.3
Fletcher, J.A.4
Xiao, S.5
-
91
-
-
84859899141
-
An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer
-
Mamo A, CavallOne L, Tuzmen S et al. An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer. Oncogene 31(16), 2090-2100 (2012).
-
(2012)
Oncogene
, vol.31
, Issue.16
, pp. 2090-2100
-
-
Mamo, A.1
CavallOne, L.2
Tuzmen, S.3
-
92
-
-
77957731999
-
Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma
-
Jones S, Wang TL, Shih IeM et al. Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science 330(6001), 228-231 (2010).
-
(2010)
Science 330
, vol.6001
, pp. 228-231
-
-
Jones, S.1
Wang, T.L.2
Shih, IeM.3
-
93
-
-
77957946398
-
ARID1A mutations in endometriosis-associated ovarian carcinomas
-
Wiegand KC, Shah SP, Al-Agha OM et al. ARID1A mutations in endometriosis-associated ovarian carcinomas. N. Engl. J. Med. 363(16), 1532-1543 (2010).
-
(2010)
N. Engl. J. Med
, vol.363
, Issue.16
, pp. 1532-1543
-
-
Wiegand, K.C.1
Shah, S.P.2
Al-Agha, O.M.3
-
94
-
-
82255183148
-
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
-
Wang K, Kan J, Yuen ST et al. Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer. Nat. Genet. 43(12), 1219-1223 (2011).
-
(2011)
Nat. Genet
, vol.43
, Issue.12
, pp. 1219-1223
-
-
Wang, K.1
Kan, J.2
Yuen, S.T.3
-
95
-
-
84857467474
-
Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types
-
Jones S, Li M, Parsons DW et al. Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types. Hum. Mutat. 33(1), 100-103 (2012).
-
(2012)
Hum. Mutat
, vol.33
, Issue.1
, pp. 100-103
-
-
Jones, S.1
Li, M.2
Parsons, D.W.3
-
96
-
-
84862976633
-
Whole-Genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
-
Fujimoto A, Totoki Y, Abe T et al. Whole-Genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat. Genet. 44(7), 760-764 (2012).
-
(2012)
Nat. Genet
, vol.44
, Issue.7
, pp. 760-764
-
-
Fujimoto, A.1
Totoki, Y.2
Abe, T.3
-
97
-
-
32944462855
-
The c-myc gene is a direct target of mammalian SWI/SNF-related complexes during differentiation-associated cell cycle arrest
-
DOI 10.1158/0008-5472.CAN-05-3427
-
Nagl NG Jr, Zweitzig DR, Thimmapaya B, Beck GR Jr, Moran E. The c-myc gene is a direct target of mammalian SWI/SNF-Related complexes during differentiation-associated cell cycle arrest. Cancer Res. 66(3), 1289-1293 (2006). (Pubitemid 43259906)
-
(2006)
Cancer Research
, vol.66
, Issue.3
, pp. 1289-1293
-
-
Nagl Jr., N.G.1
Zweitzig, D.R.2
Thimmapaya, B.3
Beck Jr., G.R.4
Moran, E.5
-
98
-
-
80155131218
-
ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers
-
Guan B, Wang TL, Shih IeM. ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers. Cancer Res. 71(21), 6718-6727 (2011).
-
(2011)
Cancer Res
, vol.71
, Issue.21
, pp. 6718-6727
-
-
Guan, B.1
Wang, T.L.2
ShihIe, M.3
-
99
-
-
80052271807
-
Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma
-
Li M, Zhao H, Zhang X et al. Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma. Nat. Genet. 43(9), 828-829 (2011).
-
(2011)
Nat. Genet
, vol.43
, Issue.9
, pp. 828-829
-
-
Li, M.1
Zhao, H.2
Zhang, X.3
-
100
-
-
23044461703
-
PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes
-
DOI 10.1101/gad.1323805
-
Yan Z, Cui K, Murray DM et al. PBAF chromatin-Remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-Responsive genes. Genes Dev. 19(14), 1662-1667 (2005). (Pubitemid 41058360)
-
(2005)
Genes and Development
, vol.19
, Issue.14
, pp. 1662-1667
-
-
Yan, Z.1
Cui, K.2
Murray, D.M.3
Ling, C.4
Xue, Y.5
Gerstein, A.6
Parsons, R.7
Zhao, K.8
Wang, W.9
-
101
-
-
40949111565
-
BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer
-
DOI 10.1158/0008-5472.CAN-07-5276
-
Xia W, Nagase S, Montia AG et al. BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer. Cancer Res. 68(6), 1667-1674 (2008). (Pubitemid 351416550)
-
(2008)
Cancer Research
, vol.68
, Issue.6
, pp. 1667-1674
-
-
Xia, W.1
Nagase, S.2
Montia, A.G.3
Kalachikov, S.M.4
Keniry, M.5
Su, T.6
Memeo, L.7
Hibshoosh, H.8
Parsons, R.9
-
102
-
-
79251635938
-
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
-
Varela I, Tarpey P, Raine K et al. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 469(7331), 539-542 (2011).
-
(2011)
Nature
, vol.469
, Issue.7331
, pp. 539-542
-
-
Varela, I.1
Tarpey, P.2
Raine, K.3
-
103
-
-
77950517628
-
BRD7 is a candidate tumour suppressor gene required for p53 function
-
Drost J, Mantovani F, Tocco F et al. BRD7 is a candidate tumour suppressor gene required for p53 function. Nat. Cell. Biol. 12(4), 380-389 (2010).
-
(2010)
Nat. Cell. Biol
, vol.12
, Issue.4
, pp. 380-389
-
-
Drost, J.1
Mantovani, F.2
Tocco, F.3
-
104
-
-
52449133461
-
Promoter methylation inhibits BRD7 expression in human nasopharyngeal carcinoma cells
-
Liu H, Zhang L, Niu Z et al. Promoter methylation inhibits BRD7 expression in human nasopharyngeal carcinoma cells. BMC Cancer 8, 253 (2008).
-
(2008)
BMC Cancer
, vol.8
, pp. 253
-
-
Liu, H.1
Zhang, L.2
Niu, Z.3
-
105
-
-
79954505570
-
SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis
-
Lin JR, Zeman MK, Chen JY, Yee MC, Cimprich KA. SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis. Mol. Cell 42(2), 237-249 (2011).
-
(2011)
Mol. Cell
, vol.42
, Issue.2
, pp. 237-249
-
-
Lin, J.R.1
Zeman, M.K.2
Chen, J.Y.3
Yee, M.C.4
Cimprich, K.A.5
-
106
-
-
18344368006
-
HLTF gene silencing in human colon cancer
-
DOI 10.1073/pnas.062459899
-
Moinova HR, Chen WD, Shen L et al. HLTF gene silencing in human colon cancer. Proc. Natl Acad. Sci. USA 99(7), 4562-4567 (2002). (Pubitemid 34286024)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.7
, pp. 4562-4567
-
-
Moinova, H.R.1
Chen, W.-D.2
Shen, L.3
Smiraglia, D.4
Olechnowicz, J.5
Ravi, L.6
Kasturi, L.7
Myeroff, L.8
Plass, C.9
Parsons, R.10
Minna, J.11
Willson, J.K.V.12
Green, S.B.13
Issa, J.-P.14
Markowitz, S.D.15
-
107
-
-
0141813518
-
DNA hypermethylation and histone hypoacetylation of the HLTF gene are associated with reduced expression in gastric carcinoma
-
DOI 10.1111/j.1349-7006.2003.tb01504.x
-
Hamai Y, Oue N, Mitani Y et al. DNA hypermethylation and hist one hypoacetylation of the HLTF gene are associated with reduced expression in gastric carcinoma. Cancer Sci. 94(8), 692-698 (2003). (Pubitemid 37160926)
-
(2003)
Cancer Science
, vol.94
, Issue.8
, pp. 692-698
-
-
Hamai, Y.1
Oue, N.2
Mitani, Y.3
Nakayama, H.4
Ito, R.5
Matsusaki, K.6
Yoshida, K.7
Toge, T.8
Yasui, W.9
-
108
-
-
67651158856
-
Methylation of helicase-like transcription factor in serum of patients with colorectal cancer is an independent predictor of disease recurrence
-
Herbst A, Wallner M, Rahmig K et al. Methylation of helicase-like transcription factor in serum of patients with colorectal cancer is an independent predictor of disease recurrence. Eur. J. Gastroenterol. Hepatol. 21(5), 565-569 (2009).
-
(2009)
Eur. J. Gastroenterol. Hepatol
, vol.21
, Issue.5
, pp. 565-569
-
-
Herbst, A.1
Wallner, M.2
Rahmig, K.3
-
109
-
-
33645321637
-
Promoter methylation of helicase-like transcription factor is associated with the early stages of gastric cancer with family history
-
Kim JJ, Chung SW, Kim JH et al. Promoter methylation of helicase-like transcription factor is associated with the early stages of gastric cancer with family history. Ann. Oncol. 17(4), 657-662 (2006).
-
(2006)
Ann. Oncol
, vol.17
, Issue.4
, pp. 657-662
-
-
Kim, J.J.1
Chung, S.W.2
Kim, J.H.3
-
110
-
-
61349151633
-
Role of chromodomain helicase DNA-Binding protein 2 in DNA damage response signaling and tumorigenesis
-
Nagarajan P, Onami TM, Rajagopalan S, Kania S, Donnell R, Venkatachalam S. Role of chromodomain helicase DNA-Binding protein 2 in DNA damage response signaling and tumorigenesis. Oncogene 28(8), 1053-1062 (2009).
-
(2009)
Oncogene
, vol.28
, Issue.8
, pp. 1053-1062
-
-
Nagarajan, P.1
Onami, T.M.2
Rajagopalan, S.3
Kania, S.4
Donnell, R.5
Venkatachalam, S.6
-
111
-
-
33846703338
-
CHD5 Is a Tumor Suppressor at Human 1p36
-
DOI 10.1016/j.cell.2006.11.052, PII S0092867407000530
-
Bagchi A, Papazoglu C, Wu Y et al. CHD5 is a tumor suppressor at human 1p36. Cell 128(3), 459-475 (2007). (Pubitemid 46198889)
-
(2007)
Cell
, vol.128
, Issue.3
, pp. 459-475
-
-
Bagchi, A.1
Papazoglu, C.2
Wu, Y.3
Capurso, D.4
Brodt, M.5
Francis, D.6
Bredel, M.7
Vogel, H.8
Mills, A.A.9
-
112
-
-
79954613030
-
Genetic and expressional alterations of CHD genes in gastric and colorectal cancers
-
Kim MS, Chung NG, Kang MR, Yoo NJ, Lee SH. Genetic and expressional alterations of CHD genes in gastric and colorectal cancers. Histopathology 58(5), 660-668 (2011).
-
(2011)
Histopathology
, vol.58
, Issue.5
, pp. 660-668
-
-
Kim, M.S.1
Chung, N.G.2
Kang, M.R.3
Yoo, N.J.4
Lee, S.H.5
-
113
-
-
55849092083
-
Mutation and methylation analysis of the chromodomain-helicase-DNA binding 5 gene in ovarian cancer
-
Gorringe KL, Choong DY, Williams LH et al. Mutation and methylation analysis of the chromodomain-helicase-DNA binding 5 gene in ovarian cancer. Neoplasia 10(11), 1253-1258 (2008).
-
(2008)
Neoplasia
, vol.10
, Issue.11
, pp. 1253-1258
-
-
Gorringe, K.L.1
Choong, D.Y.2
Williams, L.H.3
-
114
-
-
46849107117
-
CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas
-
DOI 10.1093/jnci/djn176
-
Fujita T, Igarashi J, Okawa ER et al. CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas. J. Natl Cancer Inst. 100(13), 940-949 (2008). (Pubitemid 351957513)
-
(2008)
Journal of the National Cancer Institute
, vol.100
, Issue.13
, pp. 940-949
-
-
Fujita, T.1
Igarashi, J.2
Okawa, E.R.3
Gotoh, T.4
Manne, J.5
Kolla, V.6
Kim, J.7
Zhao, H.8
Pawel, B.R.9
London, W.B.10
Maris, J.M.11
White, P.S.12
Brodeur, G.M.13
-
115
-
-
54949152670
-
Chromatin remodeling factor CHD5 is silenced by promoter CpG island hypermethylation in human cancer
-
Mulero-Navarro S, Esteller M. Chromatin remodeling factor CHD5 is silenced by promoter CpG island hypermethylation in human cancer. Epigenetics 3(4), 210-215 (2008).
-
(2008)
Epigenetics
, vol.3
, Issue.4
, pp. 210-215
-
-
Mulero-Navarro, S.1
Esteller, M.2
-
116
-
-
77957907502
-
Expression of the neuron-specific protein CHD5 is an independent marker of outcome in neuroblastoma
-
Garcia I, Mayol G, Rodriguez E et al. Expression of the neuron-specific protein CHD5 is an independent marker of outcome in neuroblastoma. Mol. Cancer 9, 277 (2010).
-
(2010)
Mol. Cancer
, vol.9
, pp. 277
-
-
Garcia, I.1
Mayol, G.2
Rodriguez, E.3
-
117
-
-
80255138705
-
CHD5 downregulation associated with poor prognosis in epithelial ovarian cancer
-
Wong RR, Chan LK, Tsang TP et al. CHD5 downregulation associated with poor prognosis in epithelial ovarian cancer. Gynecol. Obstet. Invest. 72(3), 203-207 (2011).
-
(2011)
Gynecol. Obstet. Invest
, vol.72
, Issue.3
, pp. 203-207
-
-
Wong, R.R.1
Chan, L.K.2
Tsang, T.P.3
-
118
-
-
84860327480
-
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
-
Zang ZJ, Cutcutache I, Poon SL et al. Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. Nat. Genet. 44(5), 570-574 (2012).
-
(2012)
Nat. Genet
, vol.44
, Issue.5
, pp. 570-574
-
-
Zang, Z.J.1
Cutcutache, I.2
Poon, S.L.3
-
119
-
-
84862777348
-
Driver mutations in hist one H3.3 and chromatin remodelling genes in paediatric glioblastoma
-
Schwartzentruber J, Korshunov A, Liu XY et al. Driver mutations in hist one H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 482(7384), 226-231 (2012).
-
(2012)
Nature
, vol.482
, Issue.7384
, pp. 226-231
-
-
Schwartzentruber, J.1
Korshunov, A.2
Liu, X.Y.3
-
120
-
-
84862777410
-
Somatic hist one H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-Brainstem glioblastomas
-
Wu G, Broniscer A, McEachron TA et al. Somatic hist one H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-Brainstem glioblastomas. Nat. Genet. 44(3), 251-253 (2012).
-
(2012)
Nat. Genet
, vol.44
, Issue.3
, pp. 251-253
-
-
Wu, G.1
Broniscer, A.2
McEachron, T.A.3
-
121
-
-
21744457108
-
Global histone modification patterns predict risk of prostate cancer recurrence
-
DOI 10.1038/nature03672
-
Seligson DB, Horvath S, Shi T et al. Global hist one modification patterns predict risk of prostate cancer recurrence. Nature 435(7046), 1262-1266 (2005). (Pubitemid 40943093)
-
(2005)
Nature
, vol.435
, Issue.7046
, pp. 1262-1266
-
-
Seligson, D.B.1
Horvath, S.2
Shi, T.3
Yu, H.4
Tze, S.5
Grunstein, M.6
Kurdistani, S.K.7
-
122
-
-
35348862421
-
Global histone modifications predict prognosis of resected non-small-cell lung cancer
-
DOI 10.1200/JCO.2007.11.2599
-
Barlesi F, GiaccOne G, Gallegos-Ruiz MI et al. Global hist one modifications predict prognosis of resected non-small-Cell lung cancer. J. Clin. Oncol. 25(28), 4358-4364 (2007). (Pubitemid 350013840)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.28
, pp. 4358-4364
-
-
Barlesi, F.1
Giaccone, G.2
Gallegos-Ruiz, M.I.3
Loundou, A.4
Span, S.W.5
Lefesvre, P.6
Kruyt, F.A.E.7
Rodriguez, J.A.8
-
123
-
-
12944281108
-
Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis
-
DOI 10.1073/pnas.040579497
-
Chadwick RB, Jiang GL, Bennington GA et al. Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis. Proc. Natl Acad. Sci. USA 97(6), 2662-2667 (2000). (Pubitemid 30159228)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.6
, pp. 2662-2667
-
-
Chadwick, R.B.1
Jiang, G.-L.2
Bennington, G.A.3
Yuan, B.4
Johnson, C.K.5
Stevens, M.W.6
Niemann, T.H.7
Peltomaki, P.8
Huang, S.9
De La Chapelle, A.10
-
124
-
-
77957340047
-
Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and hist one modifications
-
Zhang C, Li H, Wang Y et al. Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and hist one modifications. J. Hepatol. 53(5), 889-895 (2010).
-
(2010)
J. Hepatol
, vol.53
, Issue.5
, pp. 889-895
-
-
Zhang, C.1
Li, H.2
Wang, Y.3
|