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Volumn 109, Issue 45, 2012, Pages 18541-18546

HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo

Author keywords

T lymphocyte homing; Two photon intravital microscopy

Indexed keywords

ACTIN; NEF PROTEIN;

EID: 84868585862     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1204322109     Document Type: Article
Times cited : (58)

References (45)
  • 1
    • 77958470465 scopus 로고    scopus 로고
    • Human immunodeficiency virus (HIV) type-1, HIV-2 and simian immunodeficiency virus Nef proteins
    • Laguette N, Brégnard C, Benichou S, Basmaciogullari S (2010) Human immunodeficiency virus (HIV) type-1, HIV-2 and simian immunodeficiency virus Nef proteins. Mol Aspects Med 31(5):418-433.
    • (2010) Mol Aspects Med , vol.31 , Issue.5 , pp. 418-433
    • Laguette, N.1    Brégnard, C.2    Benichou, S.3    Basmaciogullari, S.4
  • 3
    • 70350312836 scopus 로고    scopus 로고
    • Inhibition of T-cell receptor-induced actin remodeling and relocalization of Lck are evolutionarily conserved activities of lentiviral Nef proteins
    • Rudolph JM, Eickel N, Haller C, Schindler M, Fackler OT (2009) Inhibition of T-cell receptor-induced actin remodeling and relocalization of Lck are evolutionarily conserved activities of lentiviral Nef proteins. J Virol 83(22):11528-11539.
    • (2009) J Virol , vol.83 , Issue.22 , pp. 11528-11539
    • Rudolph, J.M.1    Eickel, N.2    Haller, C.3    Schindler, M.4    Fackler, O.T.5
  • 4
    • 77950514618 scopus 로고    scopus 로고
    • Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling
    • Stolp B, Abraham L, Rudolph JM, Fackler OT (2010) Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling. J Virol 84(8):3935-3948.
    • (2010) J Virol , vol.84 , Issue.8 , pp. 3935-3948
    • Stolp, B.1    Abraham, L.2    Rudolph, J.M.3    Fackler, O.T.4
  • 5
    • 68549123450 scopus 로고    scopus 로고
    • HIV-1 Nef interferes with host cell motility by deregulation of Cofilin
    • Stolp B, et al. (2009) HIV-1 Nef interferes with host cell motility by deregulation of Cofilin. Cell Host Microbe 6(2):174-186.
    • (2009) Cell Host Microbe , vol.6 , Issue.2 , pp. 174-186
    • Stolp, B.1
  • 6
    • 0033153464 scopus 로고    scopus 로고
    • Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
    • DOI 10.1016/S1097-2765(01)80005-8
    • Fackler OT, Luo W, Geyer M, Alberts AS, Peterlin BM (1999) Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Mol Cell 3(6):729-739. (Pubitemid 29323051)
    • (1999) Molecular Cell , vol.3 , Issue.6 , pp. 729-739
    • Fackler, O.T.1    Luo, W.2    Geyer, M.3    Alberts, A.S.4    Peterlin, B.M.5
  • 7
    • 43749116673 scopus 로고    scopus 로고
    • HIV-1 Nef disrupts the podocyte actin cytoskeleton by interacting with diaphanous interacting protein
    • Lu TC, et al. (2008) HIV-1 Nef disrupts the podocyte actin cytoskeleton by interacting with diaphanous interacting protein. J Biol Chem 283(13):8173-8182.
    • (2008) J Biol Chem , vol.283 , Issue.13 , pp. 8173-8182
    • Lu, T.C.1
  • 8
    • 77649228424 scopus 로고    scopus 로고
    • HIV-1 Nef inhibits ruffles, induces filopodia, and modulates migration of infected lymphocytes
    • Nobile C, et al. (2010) HIV-1 Nef inhibits ruffles, induces filopodia, and modulates migration of infected lymphocytes. J Virol 84(5):2282-2293.
    • (2010) J Virol , vol.84 , Issue.5 , pp. 2282-2293
    • Nobile, C.1
  • 9
    • 33644778761 scopus 로고    scopus 로고
    • A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2
    • DOI 10.1128/JVI.80.6.3050-3061.2006
    • Agopian K, Wei BL, Garcia JV, Gabuzda D (2006) A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2. J Virol 80(6):3050-3061. (Pubitemid 43346400)
    • (2006) Journal of Virology , vol.80 , Issue.6 , pp. 3050-3061
    • Agopian, K.1    Wei, B.L.2    Garcia, J.V.3    Gabuzda, D.4
  • 10
    • 80052671541 scopus 로고    scopus 로고
    • Nef does not inhibit Factin remodelling and HIV-1 cell-cell transmission at the T lymphocyte virological synapse
    • Haller C, Tibroni N, Rudolph JM, Grosse R, Fackler OT (2011) Nef does not inhibit Factin remodelling and HIV-1 cell-cell transmission at the T lymphocyte virological synapse. Eur J Cell Biol 90(11):913-921.
    • (2011) Eur J Cell Biol , vol.90 , Issue.11 , pp. 913-921
    • Haller, C.1    Tibroni, N.2    Rudolph, J.M.3    Grosse, R.4    Fackler, O.T.5
  • 11
    • 36349022028 scopus 로고    scopus 로고
    • Association of Nef with p21-activated kinase 2 is dispensable for efficient human immunodeficiency virus type 1 replication and cytopathicity in ex vivo-infected human lymphoid tissue
    • DOI 10.1128/JVI.01436-07
    • Schindler M, et al. (2007) Association of Nef with p21-activated kinase 2 is dispensable for efficient human immunodeficiency virus type 1 replication and cytopathicity in ex vivo-infected human lymphoid tissue. J Virol 81(23):13005-13014. (Pubitemid 350156939)
    • (2007) Journal of Virology , vol.81 , Issue.23 , pp. 13005-13014
    • Schindler, M.1    Rajan, D.2    Specht, A.3    Ritter, C.4    Pulkkinen, K.5    Saksela, K.6    Kirchhoff, F.7
  • 13
    • 19344363916 scopus 로고    scopus 로고
    • HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis
    • Janardhan A, Swigut T, Hill B, Myers MP, Skowronski J (2004) HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis. PLoS Biol 2(1):E6.
    • (2004) PLoS Biol , vol.2 , Issue.1
    • Janardhan, A.1    Swigut, T.2    Hill, B.3    Myers, M.P.4    Skowronski, J.5
  • 14
    • 70350719372 scopus 로고    scopus 로고
    • HIV-1 Nef-mediated inhibition of T cell migration and its molecular determinants
    • Park IW, He JJ (2009) HIV-1 Nef-mediated inhibition of T cell migration and its molecular determinants. J Leukoc Biol 86(5):1171-1178.
    • (2009) J Leukoc Biol , vol.86 , Issue.5 , pp. 1171-1178
    • Park, I.W.1    He, J.J.2
  • 16
    • 77956525904 scopus 로고    scopus 로고
    • Comprehensive analysis of lymph node stroma-expressed Ig superfamily members reveals redundant and nonredundant roles for ICAM-1, ICAM-2, and VCAM-1 in lymphocyte homing
    • Boscacci RT, et al. (2010) Comprehensive analysis of lymph node stroma-expressed Ig superfamily members reveals redundant and nonredundant roles for ICAM-1, ICAM-2, and VCAM-1 in lymphocyte homing. Blood 116(6):915-925.
    • (2010) Blood , vol.116 , Issue.6 , pp. 915-925
    • Boscacci, R.T.1
  • 17
  • 18
    • 23944437624 scopus 로고    scopus 로고
    • Chemokine control of lymphocyte trafficking: A general overview
    • DOI 10.1111/j.1365-2567.2005.02183.x
    • Stein JV, Nombela-Arrieta C (2005) Chemokine control of lymphocyte trafficking: A general overview. Immunology 116(1):1-12. (Pubitemid 41208347)
    • (2005) Immunology , vol.116 , Issue.1 , pp. 1-12
    • Stein, J.V.1    Nombela-Arrieta, C.2
  • 19
    • 77955546541 scopus 로고    scopus 로고
    • Ultrastructural localization of extracellular matrix proteins of the lymph node cortex: Evidence supporting the reticular network as a pathway for lymphocyte migration
    • Sobocinski GP, et al. (2010) Ultrastructural localization of extracellular matrix proteins of the lymph node cortex: Evidence supporting the reticular network as a pathway for lymphocyte migration. BMC Immunol 11:42.
    • (2010) BMC Immunol , vol.11 , pp. 42
    • Sobocinski, G.P.1
  • 20
    • 34447569374 scopus 로고    scopus 로고
    • Gene transfer of human TCR in primary murine T cells is improved by pseudo-typing with amphotropic and ecotropic envelopes
    • DOI 10.1002/jgm.1047
    • Pouw NM, Westerlaken EJ, Willemsen RA, Debets R (2007) Gene transfer of human TCR in primary murine T cells is improved by pseudo-typing with amphotropic and ecotropic envelopes. J Gene Med 9(7):561-570. (Pubitemid 47073988)
    • (2007) Journal of Gene Medicine , vol.9 , Issue.7 , pp. 561-570
    • Pouw, N.M.C.1    Westerlaken, E.J.2    Willemsen, R.A.3    Debets, R.4
  • 21
    • 84856077084 scopus 로고    scopus 로고
    • HIV-1 Nef compensates for disorganization of the immunological synapse by inducing trans-Golgi network-associated Lck signaling
    • Pan X, et al. (2012) HIV-1 Nef compensates for disorganization of the immunological synapse by inducing trans-Golgi network-associated Lck signaling. Blood 119(3):786-797.
    • (2012) Blood , vol.119 , Issue.3 , pp. 786-797
    • Pan, X.1
  • 22
    • 33745568317 scopus 로고    scopus 로고
    • A Pak- and Pix-dependent branch of the SDF-1alpha signalling pathway mediates T cell chemotaxis across restrictive barriers
    • DOI 10.1042/BJ20051655
    • Volinsky N, Gantman A, Yablonski D (2006) A Pak-and Pix-dependent branch of the SDF-1alpha signalling pathway mediates T cell chemotaxis across restrictive barriers. Biochem J 397(1):213-222. (Pubitemid 44032853)
    • (2006) Biochemical Journal , vol.397 , Issue.1 , pp. 213-222
    • Volinsky, N.1    Gantman, A.2    Yablonski, D.3
  • 23
    • 78650475426 scopus 로고    scopus 로고
    • Critical roles for Rac GTPases in T-cell migration to and within lymph nodes
    • Faroudi M, et al. (2010) Critical roles for Rac GTPases in T-cell migration to and within lymph nodes. Blood 116(25):5536-5547.
    • (2010) Blood , vol.116 , Issue.25 , pp. 5536-5547
    • Faroudi, M.1
  • 24
    • 78049504134 scopus 로고    scopus 로고
    • Differential roles for endothelial ICAM-1, ICAM-2, and VCAM-1 in shear-resistant T cell arrest, polarization, and directed crawling on blood-brain barrier endothelium
    • Steiner O, et al. (2010) Differential roles for endothelial ICAM-1, ICAM-2, and VCAM-1 in shear-resistant T cell arrest, polarization, and directed crawling on blood-brain barrier endothelium. J Immunol 185(8):4846-4855.
    • (2010) J Immunol , vol.185 , Issue.8 , pp. 4846-4855
    • Steiner, O.1
  • 25
    • 83755222547 scopus 로고    scopus 로고
    • Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots
    • Shulman Z, et al. (2012) Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots. Nat Immunol 13(1):67-76.
    • (2012) Nat Immunol , vol.13 , Issue.1 , pp. 67-76
    • Shulman, Z.1
  • 26
    • 79952095980 scopus 로고    scopus 로고
    • Chemokine triggered integrin activation and actin remodeling events guiding lymphocyte migration across vascular barriers
    • Alon R, Shulman Z (2011) Chemokine triggered integrin activation and actin remodeling events guiding lymphocyte migration across vascular barriers. Exp Cell Res 317(5):632-641.
    • (2011) Exp Cell Res , vol.317 , Issue.5 , pp. 632-641
    • Alon, R.1    Shulman, Z.2
  • 28
    • 80052649537 scopus 로고    scopus 로고
    • In vivo analysis of uropod function during physiological T cell trafficking
    • Soriano SF, et al. (2011) In vivo analysis of uropod function during physiological T cell trafficking. J Immunol 187(5):2356-2364.
    • (2011) J Immunol , vol.187 , Issue.5 , pp. 2356-2364
    • Soriano, S.F.1
  • 29
    • 84867329009 scopus 로고    scopus 로고
    • HIV-infected T cells are migratory vehicles for viral dissemination
    • Murooka TT, et al. (2012) HIV-infected T cells are migratory vehicles for viral dissemination. Nature 490(7419):283-287.
    • (2012) Nature , vol.490 , Issue.7419 , pp. 283-287
    • Murooka, T.T.1
  • 30
    • 84862197035 scopus 로고    scopus 로고
    • Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation
    • Mukerji J, Olivieri KC, Misra V, Agopian KA, Gabuzda D (2012) Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation. Retrovirology 9:33.
    • (2012) Retrovirology , vol.9 , pp. 33
    • Mukerji, J.1    Olivieri, K.C.2    Misra, V.3    Agopian, K.A.4    Gabuzda, D.5
  • 31
    • 79751485813 scopus 로고    scopus 로고
    • Mechanisms of leukocyte transendothelial migration
    • Muller WA (2011) Mechanisms of leukocyte transendothelial migration. Annu Rev Pathol 6:323-344.
    • (2011) Annu Rev Pathol , vol.6 , pp. 323-344
    • Muller, W.A.1
  • 32
    • 0035379580 scopus 로고    scopus 로고
    • Shear forces promote lymphocyte migration across vascular endothelium bearing apical chemokines
    • DOI 10.1038/88710
    • Cinamon G, Shinder V, Alon R (2001) Shear forces promote lymphocyte migration across vascular endothelium bearing apical chemokines. Nat Immunol 2(6):515-522. (Pubitemid 33705853)
    • (2001) Nature Immunology , vol.2 , Issue.6 , pp. 515-522
    • Cinamon, G.1    Shinder, V.2    Alon, R.3
  • 33
    • 67349253158 scopus 로고    scopus 로고
    • The Rac activator Tiam1 controls efficient T-cell trafficking and route of transendothelial migration
    • Gérard A, van der Kammen RA, Janssen H, Ellenbroek SI, Collard JG (2009) The Rac activator Tiam1 controls efficient T-cell trafficking and route of transendothelial migration. Blood 113(24):6138-6147.
    • (2009) Blood , vol.113 , Issue.24 , pp. 6138-6147
    • Gérard, A.1    Van Der Kammen, R.A.2    Janssen, H.3    Ellenbroek, S.I.4    Collard, J.G.5
  • 34
    • 77955887642 scopus 로고    scopus 로고
    • Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration
    • Heasman SJ, Carlin LM, Cox S, Ng T, Ridley AJ (2010) Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration. J Cell Biol 190(4):553-563.
    • (2010) J Cell Biol , vol.190 , Issue.4 , pp. 553-563
    • Heasman, S.J.1    Carlin, L.M.2    Cox, S.3    Ng, T.4    Ridley, A.J.5
  • 35
    • 33947411398 scopus 로고    scopus 로고
    • A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress
    • Nombela-Arrieta C, et al. (2007) A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress. J Exp Med 204(3):497-510.
    • (2007) J Exp Med , vol.204 , Issue.3 , pp. 497-510
    • Nombela-Arrieta, C.1
  • 36
    • 33748304311 scopus 로고    scopus 로고
    • DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migration
    • DOI 10.1182/blood-2006-04-017608
    • Shulman Z, et al. (2006) DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migration. Blood 108(7):2150-2158. (Pubitemid 44497494)
    • (2006) Blood , vol.108 , Issue.7 , pp. 2150-2158
    • Shulman, Z.1    Pasvolsky, R.2    Woolf, E.3    Grabovsky, V.4    Feigelson, S.W.5    Erez, N.6    Fukui, Y.7    Alon, R.8
  • 37
    • 0242683360 scopus 로고    scopus 로고
    • Leukocyte polarization in cell migration and immune interactions
    • DOI 10.1093/emboj/18.3.501
    • Sánchez-Madrid F, del Pozo MA (1999) Leukocyte polarization in cell migration and immune interactions. EMBO J 18(3):501-511. (Pubitemid 29057235)
    • (1999) EMBO Journal , vol.18 , Issue.3 , pp. 501-511
    • Sanchez-Madrid, F.1    Del, P.M.A.2
  • 39
    • 63149142646 scopus 로고    scopus 로고
    • B cells in HIV infection and disease
    • Moir S, Fauci AS (2009) B cells in HIV infection and disease. Nat Rev Immunol 9(4):235-245.
    • (2009) Nat Rev Immunol , vol.9 , Issue.4 , pp. 235-245
    • Moir, S.1    Fauci, A.S.2
  • 40
    • 69949128211 scopus 로고    scopus 로고
    • Massive secretion by T cells is caused by HIV Nef in infected cells and by Nef transfer to bystander cells
    • Muratori C, et al. (2009) Massive secretion by T cells is caused by HIV Nef in infected cells and by Nef transfer to bystander cells. Cell Host Microbe 6(3):218-230.
    • (2009) Cell Host Microbe , vol.6 , Issue.3 , pp. 218-230
    • Muratori, C.1
  • 43
    • 69049119032 scopus 로고    scopus 로고
    • HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits
    • Xu W, et al. (2009) HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits. Nat Immunol 10 (9):1008-1017.
    • (2009) Nat Immunol , vol.10 , Issue.9 , pp. 1008-1017
    • Xu, W.1
  • 44
    • 79960052377 scopus 로고    scopus 로고
    • HIV-1 Nef impairs multiple T-cell functions in antigen-specific immune response in mice
    • Fujii H, et al. (2011) HIV-1 Nef impairs multiple T-cell functions in antigen-specific immune response in mice. Int Immunol 23(7):433-441.
    • (2011) Int Immunol , vol.23 , Issue.7 , pp. 433-441
    • Fujii, H.1


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