Design, synthesis and evaluation of N-(substituted benzothiazol-2-yl)amides as anticonvulsant and neuroprotective

European Journal of Medicinal Chemistry

Volumn 58, Issue , 2012, Pages 206-213

  Hassan, Mohd Zaheen ^a   Khan, Suroor A ^a   Amir, Mohd ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Amides; Anticonvulsants; Benzothiazole; Neuroprotective agents

Indexed keywords

1 (3 DIMETHYLAMINOPROPYL) 3 ETHYLCARBODIIMIDE; 2 BENZOYL N ( 5 CHLORO 6 FLUOROBENZOTHIAZOL 2 YL)BENZAMIDE; 2 BENZOYL N ( 6 BROMOBENZOTHIAZOL 2 YL)BENZAMIDE; 2 BENZOYL N ( 6 CHLOROBENZOTHIAZOL 2 YL)BENZAMIDE; 2 BENZOYL N ( 6 FLUOROBENZOTHIAZOL 2 YL)BENZAMIDE; 2 BENZOYL N ( 6 METHOXYBENZOTHIAZOL 2 YL)BENZAMIDE; 2 BENZOYL N ( 6 METHYLBENZOTHIAZOL 2 YL)BENZAMIDE; 2 BENZOYL N ( 6 NITROBENZOTHIAZOL 2 YL)BENZAMIDE; 2 BENZOYLBENZOIC ACID; 4 OXO 4 PHENYLBUTANOIC ACID; ALKANE DERIVATIVE; ANTICONVULSIVE AGENT; BENZOIC ACID DERIVATIVE; BENZOTHIAZOLE DERIVATIVE; CARBAMAZEPINE; LACTATE DEHYDROGENASE; MALONALDEHYDE; N ( 5 CHLORO 6 FLUOROBENZOTHIAZOL 2 YL) 4 OXO 4 PHENYLBUTANAMIDE; N ( 6 ACETYLBENZOTHIAZOL 2 YL) 2 BENZOYLBENZAMIDE; N ( 6 ACETYLBENZOTHIAZOL 2 YL) 4 OXO 4 PHENYLBUTANAMIDE; N ( 6 BROMOBENZOTHIAZOL 2 YL) 4 OXO 4 PHENYLBUTANAMIDE; N ( 6 CHLOROBENZOTHIAZOL 2 YL) 4 OXO 4 PHENYLBUTANAMIDE; N ( 6 FLUOROBENZOTHIAZOL 2 YL) 4 OXO 4 PHENYLBUTANAMIDE; N ( 6 METHOXYBENZOTHIAZOL 2 YL) 4 OXO 4 PHENYLBUTANAMIDE; N ( 6 METHYLBENZOTHIAZOL 2 YL) 4 OXO 4 PHENYLBUTANAMIDE; N ( 6 NITROBENZOTHIAZOL 2 YL) 4 OXO 4 PHENYLBUTANAMIDE; PHENYTOIN; PROGABIDE; REMACEMIDE; UNCLASSIFIED DRUG; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CONVULSION; CROSS COUPLING REACTION; DRUG DESIGN; DRUG DOSE; DRUG EFFECT; DRUG SYNTHESIS; LACTATE DEHYDROGENASE BLOOD LEVEL; MOUSE; NEUROPROTECTION; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ACRYLAMIDE; AMIDES; ANIMALS; ANTICONVULSANTS; BENZOTHIAZOLES; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; FEMALE; MALE; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NEUROPROTECTIVE AGENTS; PENTYLENETETRAZOLE; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP; SWIMMING;

EID: 84868239948     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.10.002     Document Type: Article

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