Synthesis of benzothiazole derivatives having acetamido and carbothioamido pharmacophore as anticonvulsant agents

Medicinal Chemistry Research

Volumn 21, Issue 9, 2012, Pages 2661-2670

  Amir, Mohd ^a   Asif, S ^a   Ali, Israr ^a   Hassan, Mohd Zaheen ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Acetamide; Anticonvulsant activity; Benzothiazole; Carbothioamide; Drug likeness

Indexed keywords

ACETAMIDE DERIVATIVE; ANTICONVULSIVE AGENT; BENZOTHIAZOLE DERIVATIVE; CARBAMAZEPINE; IMIDAZOLE DERIVATIVE; MORPHOLINE DERIVATIVE; N (6 CHLOROBENZOTHIAZOL 2 YL) 2 (1H IMIDAZOL 1 YL)ACETAMIDE; N (6 CHLOROBENZOTHIAZOL 2 YL) 2 (4 FLUOROBENZYLIDENE)HYDRAZINECARBOTHIOAMIDE; N (6 CHLOROBENZOTHIAZOL 2 YL) 2 (4 NITROBENZYLIDENE)HYDRAZINECARBOTHIOAMIDE; N (6 CHLOROBENZOTHIAZOL 2 YL) 2 MORPHOLINOACETAMIDE; PHENYTOIN; THIOAMIDE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DOSE COMPARISON; DRUG PENETRATION; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; IN VIVO STUDY; INFRARED SPECTROSCOPY; MOUSE; NEUROTOXICITY; NONHUMAN; PHARMACOPHORE; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; TONIC CLONIC SEIZURE;

EID: 84866352524     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-011-9791-1     Document Type: Article

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